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The map label for this gene is bioC [H]

Identifier: 91781673

GI number: 91781673

Start: 322944

End: 323960

Strand: Direct

Name: bioC [H]

Synonym: Bxe_A4173

Alternate gene names: 91781673

Gene position: 322944-323960 (Clockwise)

Preceding gene: 91781670

Following gene: 91781674

Centisome position: 6.6

GC content: 65.19

Gene sequence:

>1017_bases
ATGGAGGGAAACGAACGAGTATACTTCGGGCTCTACGCCAGCACGACACTCATGTCCCCAACTCCCGCTCAATCAGGCCG
TCCGGCCTATGATTCCCAGCGCCTCCGGCGGATCTTCGACCGCCGCGCGTCGACTTTCAGCGAAGTCGCGTTCCTGCCGC
GCGAAATCGCGCAGCGCATGCGCGAGCGTCTCGACTACATCAAGGTCACGCCGTCGAGCGTGCTCGACGCCGGCTGCGGC
ATGGGTGAAGACATTCCGGCTTTGCGCGAGCGCTTTCCCGAGGCGCCGGTGTTCGGCTCCGACCTGTCGCACGGCATGCT
CACGCGCGCGCTGCAGCACGATTCGGGCGACACGAGTTGGCGACGCTTTTTGCCGGCCACGCTCGGCAAGGCGCTCGGCG
CCCGCGGACCGCGCTTCGCGCAAGCCGACTTTTCGGCGCTGCCGTTCGCGGCCGGCGCCTTCGAATTTATCTGGTCCAAT
CTGGCGCTGCACTGGCACTCACGGCCCGACCTCGTGTTTCCCGAATGGCAGCGTGTGCTGAAAGTGAACGGCTTGCTGAT
GTTCAGCACGCTCGGTCCCGACTCGCTCAAGGAGCTGCGCGGCGCCTATGCCGAAGTCGAGGCCGCGCACGGCGTTGCCT
CGCGCAAGCATGTGATCGATTTCGTCGATATGCATGATCTCGGCGATATGCTGGTCGAAAGCGGCTTCGAGATACCCGTG
ATGGACCAGGAAGTCCTGACCATTACCTATAAGTCTCCCGAATCGCTGCTCGCCGACGTGCGCCGCTGGGGCGCCTATCC
GTTCGAGCGCGAAGCGTCGTCGGGCGCCGTCGCGCGCAGGCTGCACAAGGCTTTGCTGGCGGCCCTCGAAGCCCGCCGGC
GCGCCGACGGCACGCTCGCGCTGACCTTCGAGGTGATCTATGGACACGCATGGAAAGCCGTGCCGCGCACCACGGCCGAA
GGTCATGGGATCGTGCGGATCGAGGACATCGGGCGGGGTTCGGCAAGGAATCGTTGA

Upstream 100 bases:

>100_bases
AATGCACGGCGCGCGCAAAACGCGCGAACCGGCTGCCGGAAAACGACGAAATGGACCGGAGTGGCATGACTGGGCTGTCC
GCGGAGGCCTTCCACGCTGA

Downstream 100 bases:

>100_bases
GGAATCGATGAGGCGGTAAAGACGGCATCTGTTATGCCTGAAATTAGCGCTTCAAAAGACCCGCAAAAGGTGCGTCAAAA
CCGCGCGGAGGCTTGTCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEGNERVYFGLYASTTLMSPTPAQSGRPAYDSQRLRRIFDRRASTFSEVAFLPREIAQRMRERLDYIKVTPSSVLDAGCG
MGEDIPALRERFPEAPVFGSDLSHGMLTRALQHDSGDTSWRRFLPATLGKALGARGPRFAQADFSALPFAAGAFEFIWSN
LALHWHSRPDLVFPEWQRVLKVNGLLMFSTLGPDSLKELRGAYAEVEAAHGVASRKHVIDFVDMHDLGDMLVESGFEIPV
MDQEVLTITYKSPESLLADVRRWGAYPFEREASSGAVARRLHKALLAALEARRRADGTLALTFEVIYGHAWKAVPRTTAE
GHGIVRIEDIGRGSARNR

Sequences:

>Translated_338_residues
MEGNERVYFGLYASTTLMSPTPAQSGRPAYDSQRLRRIFDRRASTFSEVAFLPREIAQRMRERLDYIKVTPSSVLDAGCG
MGEDIPALRERFPEAPVFGSDLSHGMLTRALQHDSGDTSWRRFLPATLGKALGARGPRFAQADFSALPFAAGAFEFIWSN
LALHWHSRPDLVFPEWQRVLKVNGLLMFSTLGPDSLKELRGAYAEVEAAHGVASRKHVIDFVDMHDLGDMLVESGFEIPV
MDQEVLTITYKSPESLLADVRRWGAYPFEREASSGAVARRLHKALLAALEARRRADGTLALTFEVIYGHAWKAVPRTTAE
GHGIVRIEDIGRGSARNR
>Mature_338_residues
MEGNERVYFGLYASTTLMSPTPAQSGRPAYDSQRLRRIFDRRASTFSEVAFLPREIAQRMRERLDYIKVTPSSVLDAGCG
MGEDIPALRERFPEAPVFGSDLSHGMLTRALQHDSGDTSWRRFLPATLGKALGARGPRFAQADFSALPFAAGAFEFIWSN
LALHWHSRPDLVFPEWQRVLKVNGLLMFSTLGPDSLKELRGAYAEVEAAHGVASRKHVIDFVDMHDLGDMLVESGFEIPV
MDQEVLTITYKSPESLLADVRRWGAYPFEREASSGAVARRLHKALLAALEARRRADGTLALTFEVIYGHAWKAVPRTTAE
GHGIVRIEDIGRGSARNR

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI40018642, Length=312, Percent_Identity=23.3974358974359, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786994, Length=162, Percent_Identity=32.7160493827161, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17535003, Length=312, Percent_Identity=24.6794871794872, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922210, Length=321, Percent_Identity=26.791277258567, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 37673; Mature: 37673

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGNERVYFGLYASTTLMSPTPAQSGRPAYDSQRLRRIFDRRASTFSEVAFLPREIAQRM
CCCCCEEEEEEEEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERLDYIKVTPSSVLDAGCGMGEDIPALRERFPEAPVFGSDLSHGMLTRALQHDSGDTSW
HHHHHEEECCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHH
RRFLPATLGKALGARGPRFAQADFSALPFAAGAFEFIWSNLALHWHSRPDLVFPEWQRVL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCHHHHHHH
KVNGLLMFSTLGPDSLKELRGAYAEVEAAHGVASRKHVIDFVDMHDLGDMLVESGFEIPV
HHCCEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
MDQEVLTITYKSPESLLADVRRWGAYPFEREASSGAVARRLHKALLAALEARRRADGTLA
ECCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
LTFEVIYGHAWKAVPRTTAEGHGIVRIEDIGRGSARNR
EEEEEHHCCHHHCCCCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MEGNERVYFGLYASTTLMSPTPAQSGRPAYDSQRLRRIFDRRASTFSEVAFLPREIAQRM
CCCCCEEEEEEEEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RERLDYIKVTPSSVLDAGCGMGEDIPALRERFPEAPVFGSDLSHGMLTRALQHDSGDTSW
HHHHHEEECCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHH
RRFLPATLGKALGARGPRFAQADFSALPFAAGAFEFIWSNLALHWHSRPDLVFPEWQRVL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCHHHHHHH
KVNGLLMFSTLGPDSLKELRGAYAEVEAAHGVASRKHVIDFVDMHDLGDMLVESGFEIPV
HHCCEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
MDQEVLTITYKSPESLLADVRRWGAYPFEREASSGAVARRLHKALLAALEARRRADGTLA
ECCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
LTFEVIYGHAWKAVPRTTAEGHGIVRIEDIGRGSARNR
EEEEEHHCCHHHCCCCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]