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The map label for this gene is can [H]

Identifier: 91781592

GI number: 91781592

Start: 241369

End: 242145

Strand: Reverse

Name: can [H]

Synonym: Bxe_A4254

Alternate gene names: 91781592

Gene position: 242145-241369 (Counterclockwise)

Preceding gene: 91781593

Following gene: 91781591

Centisome position: 4.95

GC content: 63.45

Gene sequence:

>777_bases
ATGAACACTAACGCTTCGCCTCCTGACAATCCGCTCTCGCATCTGTTCGACAACAACGAAGCGTGGGTTGCCCGCAAGCT
GTCCGAAGACCCTGAGTATTTTTCGCGCCTCGCTCATCAGCAGACGCCCGAGTATCTGTGGATCGGCTGCTCCGATTCGC
GCGTGCCGGCGAACCAGATCATCGGCCTGCCGCCGGGCGAAGTGTTCGTGCACAGAAACATTGCCAACGTGGTGGTGCAT
ACCGATCTGAACTGTCTGTCGGTCATCCAGTTCGCCGTCGATCTGCTGAAGGTCAAGCACATCATGGTGGTCGGCCACTA
CGGCTGCTCGGGCGTCGGCGCGGCGCTGCACGGCCGCCGCGTGGGTCTCGCGGACAACTGGCTGCATCACGTGCAGGACG
TGCGCACCAAGCATGCGGCGCTGATCGAGGAATGGCCGATCGGTGAGGCGCGTCACCGGCGCCTGGTCGAACTGAACGCG
ATCGAACAGGTGATGAACGTATGCCGCACCACCATCGTCAACGACGCGTGGGCACGCGGCCAGGAGTTGACCGTGCACGG
CTGGGCGTATGGCGTGCATGACGGCAAGGTGCGCAATCTCGGCATGACGATCCGCGAGCCGGGCGCGCTCGACGCAACCT
ATCAGAAGTGTGTGGCGGCAGTGTCGGCCGGCGGCGCACACAACGCGGACAACGACGTGGTGGCCGCCGACGCGGCGCAG
CTCGGCGACGTGCCGGCCATTGTCGAAGGCGTCATCAAGGAGCTTAAACATGAGTGA

Upstream 100 bases:

>100_bases
GCGTGAGACTCATACGCTGCTCGCCGTGTTGAATGCCTCGTCCTAACCTTATGTAACGACATCGACCGGTCAAGCGGTCG
AGCAACCACTCAGACGCACC

Downstream 100 bases:

>100_bases
GACACACATGAGCGGGACAAAAGCTGATCCGATCGTCATCGTGGGCGTGGCCCGCACGCCGATGGCGGCATTCCAGGGCG
ACTTCGCCACGCTGAGCGCG

Product: putative carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNTNASPPDNPLSHLFDNNEAWVARKLSEDPEYFSRLAHQQTPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVH
TDLNCLSVIQFAVDLLKVKHIMVVGHYGCSGVGAALHGRRVGLADNWLHHVQDVRTKHAALIEEWPIGEARHRRLVELNA
IEQVMNVCRTTIVNDAWARGQELTVHGWAYGVHDGKVRNLGMTIREPGALDATYQKCVAAVSAGGAHNADNDVVAADAAQ
LGDVPAIVEGVIKELKHE

Sequences:

>Translated_258_residues
MNTNASPPDNPLSHLFDNNEAWVARKLSEDPEYFSRLAHQQTPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVH
TDLNCLSVIQFAVDLLKVKHIMVVGHYGCSGVGAALHGRRVGLADNWLHHVQDVRTKHAALIEEWPIGEARHRRLVELNA
IEQVMNVCRTTIVNDAWARGQELTVHGWAYGVHDGKVRNLGMTIREPGALDATYQKCVAAVSAGGAHNADNDVVAADAAQ
LGDVPAIVEGVIKELKHE
>Mature_258_residues
MNTNASPPDNPLSHLFDNNEAWVARKLSEDPEYFSRLAHQQTPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVH
TDLNCLSVIQFAVDLLKVKHIMVVGHYGCSGVGAALHGRRVGLADNWLHHVQDVRTKHAALIEEWPIGEARHRRLVELNA
IEQVMNVCRTTIVNDAWARGQELTVHGWAYGVHDGKVRNLGMTIREPGALDATYQKCVAAVSAGGAHNADNDVVAADAAQ
LGDVPAIVEGVIKELKHE

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=205, Percent_Identity=52.1951219512195, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI1786534, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324292, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 28277; Mature: 28277

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNASPPDNPLSHLFDNNEAWVARKLSEDPEYFSRLAHQQTPEYLWIGCSDSRVPANQI
CCCCCCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHE
IGLPPGEVFVHRNIANVVVHTDLNCLSVIQFAVDLLKVKHIMVVGHYGCSGVGAALHGRR
ECCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCC
VGLADNWLHHVQDVRTKHAALIEEWPIGEARHRRLVELNAIEQVMNVCRTTIVNDAWARG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QELTVHGWAYGVHDGKVRNLGMTIREPGALDATYQKCVAAVSAGGAHNADNDVVAADAAQ
CEEEEEEEEEECCCCCEEECCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECHHH
LGDVPAIVEGVIKELKHE
HCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTNASPPDNPLSHLFDNNEAWVARKLSEDPEYFSRLAHQQTPEYLWIGCSDSRVPANQI
CCCCCCCCCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHE
IGLPPGEVFVHRNIANVVVHTDLNCLSVIQFAVDLLKVKHIMVVGHYGCSGVGAALHGRR
ECCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCC
VGLADNWLHHVQDVRTKHAALIEEWPIGEARHRRLVELNAIEQVMNVCRTTIVNDAWARG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QELTVHGWAYGVHDGKVRNLGMTIREPGALDATYQKCVAAVSAGGAHNADNDVVAADAAQ
CEEEEEEEEEECCCCCEEECCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECHHH
LGDVPAIVEGVIKELKHE
HCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]