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The map label for this gene is mrdB [H]

Identifier: 91781444

GI number: 91781444

Start: 75294

End: 76442

Strand: Reverse

Name: mrdB [H]

Synonym: Bxe_A4402

Alternate gene names: 91781444

Gene position: 76442-75294 (Counterclockwise)

Preceding gene: 91781445

Following gene: 91781438

Centisome position: 1.56

GC content: 62.05

Gene sequence:

>1149_bases
ATGCAATTCGACAAGCGCGCCTGGCTCGATCGCATCAAGCGGATGTTCGCGGGCTTCGACCGTCCGCTCGCACTGATCGT
GTTTCTGCTTTTGTGCGTCGGCATCGTCACGCTGTACAGCGCGAGTCTGGACGTCCCCGGCCGCGTGGAAGACCAGTTGC
GCAACATCATGCTGACGTTCGTGCTGATGTGGGCGCTCGCCAATGTTCCGCCCACCACGCTGATGCGCTTCGCGGTCCCG
CTCTACACATTCGGGATTGCGTTGCTGGTCGCGGTGGCGCTATTCGGCCTCACGCGCAAGGGCGCGAAGCGCTGGATCAA
TGTCGGCGTGGTGATCCAGCCGTCTGAAATCCTGAAGATCGCCACGCCGCTGATGCTTGCGTGGTACTACCAGCGCCGCG
AAGGCGTGATGCGCTGGTACGATTTTCTGGTCGGTCTGCTAATTCTCGCAGTGCCGGTCGGCCTGATCGCCAAACAACCC
GACCTCGGTACGGCGGTGCTGGTGTTCGCGGCCGGCTTCTTCGTGATTTACTTCGCGGGTCTGAGTTTCAAGCTGATCGT
GCCGGTGCTGATTGCAGGCGTGATCGCGGTCGGCTCCATCGCCGCCTTCCAGGACAAGATCTGTCAGCCCGAAGTGCAAT
GGCCGCTGATGCACGACTATCAGAAGCACCGTATCTGCACGCTGCTCGATCCGACCTCCGACCCGCTCGGCAAGGGCTTC
CACACCATCCAGGCCGTCATTGCGATCGGCTCGGGTGGTGCGTTCGGCAAAGGCTGGCTGAAGGGCACGCAGGCGCATCT
GGAGTTCATCCCCGAAAAGCACACCGACTTCATCTTCGCGGTGTTCTCCGAAGAGTTCGGACTGGCGGGCGGCATCGTGC
TGCTCACGCTGTACATGCTGCTGATCGCGCGCGGGCTGTATATCGCGGCCAATGGCGCGACGCTATTCGGACGCCTGCTG
GCCGGCTCGCTGACAATGGCGTTCTTCACCTACGCATTCGTGAATATCGGCATGGTGAGCGGCATCCTGCCGGTGGTCGG
CGTGCCGTTGCCGTTCATGAGCTATGGCGGCACGGCGCTGACCACGTTGGGGGTTGCCATCGGCCTCATCATGAGCATCG
CGCGGCAGAAGCGGTTGATGCAGAGCTAG

Upstream 100 bases:

>100_bases
CCGGCGCCGAGCGCCGCGGCACCGTCGCGCGATGACGGTATTCAGGCCACGTCGCCACGCCAGCCGGTTTCCGGCGGCAT
CGACGAGTAAGGAGAAAGGC

Downstream 100 bases:

>100_bases
CAAGTGCGGTGGGCATGTTGCAGAGCGCGAACATGGCCCGAAACATCGCTACACAAGCCGAAGGGGGCGCACCATCATCA
CGGAGCGCCCCCTGTTCATT

Product: putative rod shape-determining protein, rodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFDKRAWLDRIKRMFAGFDRPLALIVFLLLCVGIVTLYSASLDVPGRVEDQLRNIMLTFVLMWALANVPPTTLMRFAVP
LYTFGIALLVAVALFGLTRKGAKRWINVGVVIQPSEILKIATPLMLAWYYQRREGVMRWYDFLVGLLILAVPVGLIAKQP
DLGTAVLVFAAGFFVIYFAGLSFKLIVPVLIAGVIAVGSIAAFQDKICQPEVQWPLMHDYQKHRICTLLDPTSDPLGKGF
HTIQAVIAIGSGGAFGKGWLKGTQAHLEFIPEKHTDFIFAVFSEEFGLAGGIVLLTLYMLLIARGLYIAANGATLFGRLL
AGSLTMAFFTYAFVNIGMVSGILPVVGVPLPFMSYGGTALTTLGVAIGLIMSIARQKRLMQS

Sequences:

>Translated_382_residues
MQFDKRAWLDRIKRMFAGFDRPLALIVFLLLCVGIVTLYSASLDVPGRVEDQLRNIMLTFVLMWALANVPPTTLMRFAVP
LYTFGIALLVAVALFGLTRKGAKRWINVGVVIQPSEILKIATPLMLAWYYQRREGVMRWYDFLVGLLILAVPVGLIAKQP
DLGTAVLVFAAGFFVIYFAGLSFKLIVPVLIAGVIAVGSIAAFQDKICQPEVQWPLMHDYQKHRICTLLDPTSDPLGKGF
HTIQAVIAIGSGGAFGKGWLKGTQAHLEFIPEKHTDFIFAVFSEEFGLAGGIVLLTLYMLLIARGLYIAANGATLFGRLL
AGSLTMAFFTYAFVNIGMVSGILPVVGVPLPFMSYGGTALTTLGVAIGLIMSIARQKRLMQS
>Mature_382_residues
MQFDKRAWLDRIKRMFAGFDRPLALIVFLLLCVGIVTLYSASLDVPGRVEDQLRNIMLTFVLMWALANVPPTTLMRFAVP
LYTFGIALLVAVALFGLTRKGAKRWINVGVVIQPSEILKIATPLMLAWYYQRREGVMRWYDFLVGLLILAVPVGLIAKQP
DLGTAVLVFAAGFFVIYFAGLSFKLIVPVLIAGVIAVGSIAAFQDKICQPEVQWPLMHDYQKHRICTLLDPTSDPLGKGF
HTIQAVIAIGSGGAFGKGWLKGTQAHLEFIPEKHTDFIFAVFSEEFGLAGGIVLLTLYMLLIARGLYIAANGATLFGRLL
AGSLTMAFFTYAFVNIGMVSGILPVVGVPLPFMSYGGTALTTLGVAIGLIMSIARQKRLMQS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=380, Percent_Identity=47.3684210526316, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1786277, Length=383, Percent_Identity=30.0261096605744, Blast_Score=155, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41797; Mature: 41797

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKRAWLDRIKRMFAGFDRPLALIVFLLLCVGIVTLYSASLDVPGRVEDQLRNIMLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWALANVPPTTLMRFAVPLYTFGIALLVAVALFGLTRKGAKRWINVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEEECCHHHHHH
ATPLMLAWYYQRREGVMRWYDFLVGLLILAVPVGLIAKQPDLGTAVLVFAAGFFVIYFAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
LSFKLIVPVLIAGVIAVGSIAAFQDKICQPEVQWPLMHDYQKHRICTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGAFGKGWLKGTQAHLEFIPEKHTDFIFAVFSEEFGLAGGIVLLTLYML
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHH
LIARGLYIAANGATLFGRLLAGSLTMAFFTYAFVNIGMVSGILPVVGVPLPFMSYGGTAL
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGVAIGLIMSIARQKRLMQS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFDKRAWLDRIKRMFAGFDRPLALIVFLLLCVGIVTLYSASLDVPGRVEDQLRNIMLTF
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWALANVPPTTLMRFAVPLYTFGIALLVAVALFGLTRKGAKRWINVGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEEECCHHHHHH
ATPLMLAWYYQRREGVMRWYDFLVGLLILAVPVGLIAKQPDLGTAVLVFAAGFFVIYFAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
LSFKLIVPVLIAGVIAVGSIAAFQDKICQPEVQWPLMHDYQKHRICTLLDPTSDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEEECCCCCCCCCHH
HTIQAVIAIGSGGAFGKGWLKGTQAHLEFIPEKHTDFIFAVFSEEFGLAGGIVLLTLYML
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHH
LIARGLYIAANGATLFGRLLAGSLTMAFFTYAFVNIGMVSGILPVVGVPLPFMSYGGTAL
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
TTLGVAIGLIMSIARQKRLMQS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]