Click here to switch to the map view.

The map label for this gene is ntrC [H]

Identifier: 91781437

GI number: 91781437

Start: 70294

End: 70983

Strand: Direct

Name: ntrC [H]

Synonym: Bxe_A4409

Alternate gene names: 91781437

Gene position: 70294-70983 (Clockwise)

Preceding gene: 91781436

Following gene: 91781439

Centisome position: 1.44

GC content: 64.78

Gene sequence:

>690_bases
ATGGCAACCATCCTGGTGGTAGATGATGAAATGGGCATCCGGGAATTGCTCTCGGAGATCCTGAGCGACGAAGGGCATGT
CGTGGAGGCCGCGGAAAACGCGCAGGAAGCGCGCGAGTTCCGTTTGCGCCAGGCGCCCGACCTGGTGCTGCTCGACATCT
GGATGCCCGACACCGACGGCGTGACCTTGCTCAAGGAATGGGCGGCCCAAGGGCAACTCACCATGCCGGTGATCATGATG
TCCGGCCACGCGACGATCGATACGGCGGTTGAAGCAACCAAGATCGGCGCGCTCAATTTCCTGGAAAAGCCGATTGCCTT
GCAGAAGCTGCTGAAGGCCGTCGAGCAGGGCCTCGCGCGCGGCAACGCGGCGGGTGCGCCGGGCGGCGCGGCGGCCAAGC
CGGTGTCGCCGGTGAGCGCCTCGGCGGTGGCTTCGGCGGCGGCCTTGCCGATGCTTTCCACCGACGGCCTCGGCAGCGGC
GCGCTGGCTGCGCAAACTGCCTCGATCTCGTTCGATATACCGCTGCGCGACGCGCGCGATGCGTTCGAACGCGCGTACTT
CGAATATCACCTCGCGCGTGAGAACGGCAGCATGACGCGCGTGGCGGAGAAGACCGGCCTGGAGCGCACGCACCTGTATC
GCAAGCTCAAACAACTGGGCGTCGATCTCGGCAAAAACAAAGGTGAGTGA

Upstream 100 bases:

>100_bases
GGCAGACGATGCCGCGACACCTGGAACAGGGCCGCGTCCGGCGCACGGCGGTGCGTCGCAGGGAAAGACAAAAGCAACAG
TGCAGACAAGGGCAGCGTAA

Downstream 100 bases:

>100_bases
GGCCCGTGACCGGCGCAAGTGAGGTCCGGCGCTCCGCTTGCAGATTCCATGCTCACACATTTTTTCGACAAGGGGCTTGC
CCCACTGCAGACCCTTTGAT

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MATILVVDDEMGIRELLSEILSDEGHVVEAAENAQEAREFRLRQAPDLVLLDIWMPDTDGVTLLKEWAAQGQLTMPVIMM
SGHATIDTAVEATKIGALNFLEKPIALQKLLKAVEQGLARGNAAGAPGGAAAKPVSPVSASAVASAAALPMLSTDGLGSG
ALAAQTASISFDIPLRDARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVDLGKNKGE

Sequences:

>Translated_229_residues
MATILVVDDEMGIRELLSEILSDEGHVVEAAENAQEAREFRLRQAPDLVLLDIWMPDTDGVTLLKEWAAQGQLTMPVIMM
SGHATIDTAVEATKIGALNFLEKPIALQKLLKAVEQGLARGNAAGAPGGAAAKPVSPVSASAVASAAALPMLSTDGLGSG
ALAAQTASISFDIPLRDARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVDLGKNKGE
>Mature_228_residues
ATILVVDDEMGIRELLSEILSDEGHVVEAAENAQEAREFRLRQAPDLVLLDIWMPDTDGVTLLKEWAAQGQLTMPVIMMS
GHATIDTAVEATKIGALNFLEKPIALQKLLKAVEQGLARGNAAGAPGGAAAKPVSPVSASAVASAAALPMLSTDGLGSGA
LAAQTASISFDIPLRDARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVDLGKNKGE

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=39.1304347826087, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=37.3983739837398, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=34.6774193548387, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787375, Length=131, Percent_Identity=29.0076335877863, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789809, Length=131, Percent_Identity=30.5343511450382, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786911, Length=130, Percent_Identity=32.3076923076923, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786784, Length=121, Percent_Identity=31.404958677686, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788905, Length=117, Percent_Identity=37.6068376068376, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 24377; Mature: 24246

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILVVDDEMGIRELLSEILSDEGHVVEAAENAQEAREFRLRQAPDLVLLDIWMPDTDG
CEEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
VTLLKEWAAQGQLTMPVIMMSGHATIDTAVEATKIGALNFLEKPIALQKLLKAVEQGLAR
HHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GNAAGAPGGAAAKPVSPVSASAVASAAALPMLSTDGLGSGALAAQTASISFDIPLRDARD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEEEECCCHHHHH
AFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVDLGKNKGE
HHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ATILVVDDEMGIRELLSEILSDEGHVVEAAENAQEAREFRLRQAPDLVLLDIWMPDTDG
EEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
VTLLKEWAAQGQLTMPVIMMSGHATIDTAVEATKIGALNFLEKPIALQKLLKAVEQGLAR
HHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GNAAGAPGGAAAKPVSPVSASAVASAAALPMLSTDGLGSGALAAQTASISFDIPLRDARD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEEEECCCHHHHH
AFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVDLGKNKGE
HHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8095910 [H]