| Definition | Burkholderia xenovorans LB400 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007951 |
| Length | 4,895,836 |
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The map label for this gene is gyrB [H]
Identifier: 91781387
GI number: 91781387
Start: 3266
End: 5737
Strand: Direct
Name: gyrB [H]
Synonym: Bxe_A4460
Alternate gene names: 91781387
Gene position: 3266-5737 (Clockwise)
Preceding gene: 91781386
Following gene: 91781391
Centisome position: 0.07
GC content: 57.48
Gene sequence:
>2472_bases ATGACTGAAACGAACAATTCGCAACCCGACAACAGCTACGGCGCATCCTCGATTCAGATCCTCGAAGGTCTGGAGGCGGT GCGCAAGCGGCCCGGGATGTACATCGGGGATACATCGGACGGGACCGGTCTGCATCACCTCGTATTTGAAGTGCTGGACA ACTCCATCGACGAAGCGTTGGCGGGGCATTGCAACGACATCCAGGTGATCATTCACGCGGACAACTCCATTTCCATCACC GACAACGGCCGCGGCGTGCCGACCGGCCTGAAGATGGACGACAAGCACGATCCGAAGCGCAGCGCCGCTGAAATCGTGAT GACCGAGTTGCACGCCGGCGGCAAGTTCGACCAGAACAGCTACAAGGTGTCCGGCGGCCTGCACGGCGTGGGCGTGTCGT GCGTGAACGCATTGTCCGCGTGGCTGCGTTTGACCATTCGCCGCGACGGCAAGAAGCACTTCATGGAATTCCACCGTGGC GTGCCGCAGAACCGCATTATCGAAGAGATCGACGGCGTGGCTGTTTCGCCGATTCAAGTCACCGGCGAGACCGAAAACCG CGGCACCGAAGTGCACTTTCTCGCCGACGAGACGATTTTCGGCAACATCGAATATCACTACGACATTCTGGCCAAGCGGA TTCGCGAACTGTCGTTCCTGAATAACGGCGTGCGAATCAAGCTGACCGATCAGCGCACCGGCAAGGAAGAAGATTTCGCG TTCGTAGGCGGCGTGAAGGGCTTTGTCGAGTACATCAACAAGAACAAGTCCGTGCTGCACCCGAACATTTTCCACATCAG CGGCGAGAAAGACGGCGTGGGCGTGGAAGTGGCGATGCAGTGGAACGACAGCTACAACGAAAACGTGCTGTGCTTCACGA ACAACATTCCGCAGCGCGATGGTGGGACGCACCTGACCGGATTGCGTGCGGCGATGACGCGCGTGTTGAACAAGTACATC AACGATCACGAAGTTGCGAAGAAGGCGAAGGTCGAGACTTCTGGCGACGATATGCGTGAAGGGTTGTCGTGCGTGTTGTC GGTGAAGGTGCCGGAGCCGAAGTTCAGCGCGCAGACGAAGGACAAGCTGGTGTCGTCGGAAGTGCGCGCGCCGGTGGAGG ATGTGGTCGCGAAGGCGCTCGAAGAGTTTCTGCTCGAGACGCCGAATGACGCGAAGATTATTTGCAGCAAGATTGTCGAT GCCGCGCGCGCGCGGGATGCGGCCCGGAAGGCGCGTGAAATGACGCGTCGCAAGGGTGTGCTCGACGGCGTGGGTCTGCC TGGGAAGCTGGCGGATTGCCAGGAGAAGGACCCGGCGAAGTCCGAGATTTATATCGTCGAAGGTGACTCGGCAGGCGGGT CGGCCAAGCAGGGCCGGGATCGGAAGTTTCAGGCGATTTTGCCGCTGCGCGGCAAGGTGCTGAATGTGGAGAAGGCGAGG TATGACAAGCTGCTTTCTTCGGAGCAGATTGTTACGCTGATTACTGCTCTCGGTTGCGGGATTGGTAAGGAAGACTACAA CCTCGATAAGCTGCGTTATCACCGCATCATCATCATGACCGATGCTGACGTTGACGGTGCGCACATCCGGACGTTGTTGC TGACGTTCTTCTATCGGCAGATGCCGGAGATGATCGAGCGTGGGTATATCTATATCGCGCAGCCGCCGCTGTTCAAGATC AAGGCGGGCAAGGACGAACGGTATTTGAAGGATGAGGCTGAGGTCAATGCTCACATTCTGAAGCTGGCGTTGCAGGGGTC GGAGTTGCTCGCTTCGGAAGGCGCTACGCCGATTACTGGAGATGCGTTGGGTGAGTTGGCTCGGGCTTATCTGTTGGCTC AGGCTGTGGTTAATCGTTTGAGCCGGTTGTATGACGCTGGGGCGCTCGAGGCTGTGATGGATGGGGTCGTTGTCGATCTG TCCAGCGAGGAAGCGGCTGAAGTGTCGGCGGCGGCGCTTGAGGCCAAGTTGCGGGATGATGCGTTGAAGCCTGAAGTTAA GGTCACGACGATGTATGACCCGGTTCGTGAACTGCGCTCGCTGCGGGTTGCGCGGACGCATCACGGGAATCAGAAGATTT CTGTGCTGGATCAGGATTTTCAGCTCACTGCTGATTACCAGCAGCTGATCAACACCGCTAATACGTTTAAGGGGTTGATT GGGACGGGTGCCGTCATCAAACGTGGCGAACGGAGTATGGCTGTTACTGACTTCAAGTCCGCTATGAAGTGGTTGTTGGC TGATGCCGAGCGAAATATCTCGAAGCAGCGCTATAAGGGCCTCGGTGAAATGAATCCTGGGCAGCTTTGGGAGACTACGA TGGATCCGACGGTGCGTCGTCTTCTTCGGGTGCAGATCGAGGATGCTATTGCGGCTGATGGCATTTTCACCACGCTCATG GGGGATGATGTGGAGCCGCGTAGGGCGTTTATTGAGTCGAATGCGTTGCGGGCGGGGAATATCGACGTTTGA
Upstream 100 bases:
>100_bases GAGAACACACCAAGGGGCGCAGCGCCCCTTTGGCGTTTTTATGGTGATTTGAAAAGTCCCGAGCAGCAACCTTGCAGCAA CGCAGAACCGGAAAAAATCC
Downstream 100 bases:
>100_bases GGGTTGTTGTAGCAAGAGCCATAAAGCTGGATTTTGGGAAGCATCCATCTGGATTTTTATTGAATGATGCGTCCCAATAG TTCAAACTGATGACGCCTGT
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 823; Mature: 822
Protein sequence:
>823_residues MTETNNSQPDNSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEALAGHCNDIQVIIHADNSISIT DNGRGVPTGLKMDDKHDPKRSAAEIVMTELHAGGKFDQNSYKVSGGLHGVGVSCVNALSAWLRLTIRRDGKKHFMEFHRG VPQNRIIEEIDGVAVSPIQVTGETENRGTEVHFLADETIFGNIEYHYDILAKRIRELSFLNNGVRIKLTDQRTGKEEDFA FVGGVKGFVEYINKNKSVLHPNIFHISGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRDGGTHLTGLRAAMTRVLNKYI NDHEVAKKAKVETSGDDMREGLSCVLSVKVPEPKFSAQTKDKLVSSEVRAPVEDVVAKALEEFLLETPNDAKIICSKIVD AARARDAARKAREMTRRKGVLDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR YDKLLSSEQIVTLITALGCGIGKEDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPEMIERGYIYIAQPPLFKI KAGKDERYLKDEAEVNAHILKLALQGSELLASEGATPITGDALGELARAYLLAQAVVNRLSRLYDAGALEAVMDGVVVDL SSEEAAEVSAAALEAKLRDDALKPEVKVTTMYDPVRELRSLRVARTHHGNQKISVLDQDFQLTADYQQLINTANTFKGLI GTGAVIKRGERSMAVTDFKSAMKWLLADAERNISKQRYKGLGEMNPGQLWETTMDPTVRRLLRVQIEDAIAADGIFTTLM GDDVEPRRAFIESNALRAGNIDV
Sequences:
>Translated_823_residues MTETNNSQPDNSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEALAGHCNDIQVIIHADNSISIT DNGRGVPTGLKMDDKHDPKRSAAEIVMTELHAGGKFDQNSYKVSGGLHGVGVSCVNALSAWLRLTIRRDGKKHFMEFHRG VPQNRIIEEIDGVAVSPIQVTGETENRGTEVHFLADETIFGNIEYHYDILAKRIRELSFLNNGVRIKLTDQRTGKEEDFA FVGGVKGFVEYINKNKSVLHPNIFHISGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRDGGTHLTGLRAAMTRVLNKYI NDHEVAKKAKVETSGDDMREGLSCVLSVKVPEPKFSAQTKDKLVSSEVRAPVEDVVAKALEEFLLETPNDAKIICSKIVD AARARDAARKAREMTRRKGVLDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR YDKLLSSEQIVTLITALGCGIGKEDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPEMIERGYIYIAQPPLFKI KAGKDERYLKDEAEVNAHILKLALQGSELLASEGATPITGDALGELARAYLLAQAVVNRLSRLYDAGALEAVMDGVVVDL SSEEAAEVSAAALEAKLRDDALKPEVKVTTMYDPVRELRSLRVARTHHGNQKISVLDQDFQLTADYQQLINTANTFKGLI GTGAVIKRGERSMAVTDFKSAMKWLLADAERNISKQRYKGLGEMNPGQLWETTMDPTVRRLLRVQIEDAIAADGIFTTLM GDDVEPRRAFIESNALRAGNIDV >Mature_822_residues TETNNSQPDNSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEALAGHCNDIQVIIHADNSISITD NGRGVPTGLKMDDKHDPKRSAAEIVMTELHAGGKFDQNSYKVSGGLHGVGVSCVNALSAWLRLTIRRDGKKHFMEFHRGV PQNRIIEEIDGVAVSPIQVTGETENRGTEVHFLADETIFGNIEYHYDILAKRIRELSFLNNGVRIKLTDQRTGKEEDFAF VGGVKGFVEYINKNKSVLHPNIFHISGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRDGGTHLTGLRAAMTRVLNKYIN DHEVAKKAKVETSGDDMREGLSCVLSVKVPEPKFSAQTKDKLVSSEVRAPVEDVVAKALEEFLLETPNDAKIICSKIVDA ARARDAARKAREMTRRKGVLDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKARY DKLLSSEQIVTLITALGCGIGKEDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPEMIERGYIYIAQPPLFKIK AGKDERYLKDEAEVNAHILKLALQGSELLASEGATPITGDALGELARAYLLAQAVVNRLSRLYDAGALEAVMDGVVVDLS SEEAAEVSAAALEAKLRDDALKPEVKVTTMYDPVRELRSLRVARTHHGNQKISVLDQDFQLTADYQQLINTANTFKGLIG TGAVIKRGERSMAVTDFKSAMKWLLADAERNISKQRYKGLGEMNPGQLWETTMDPTVRRLLRVQIEDAIAADGIFTTLMG DDVEPRRAFIESNALRAGNIDV
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=560, Percent_Identity=23.5714285714286, Blast_Score=108, Evalue=2e-23, Organism=Homo sapiens, GI19913406, Length=549, Percent_Identity=22.9508196721311, Blast_Score=102, Evalue=2e-21, Organism=Escherichia coli, GI48994957, Length=825, Percent_Identity=58.9090909090909, Blast_Score=962, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=569, Percent_Identity=37.0826010544815, Blast_Score=367, Evalue=1e-102, Organism=Caenorhabditis elegans, GI17535065, Length=598, Percent_Identity=23.4113712374582, Blast_Score=114, Evalue=2e-25, Organism=Caenorhabditis elegans, GI212645845, Length=531, Percent_Identity=23.1638418079096, Blast_Score=101, Evalue=2e-21, Organism=Caenorhabditis elegans, GI212645657, Length=154, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=608, Percent_Identity=24.5065789473684, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI17136538, Length=559, Percent_Identity=23.4347048300537, Blast_Score=107, Evalue=4e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 90827; Mature: 90696
Theoretical pI: Translated: 6.20; Mature: 6.20
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTETNNSQPDNSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEAL CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH AGHCNDIQVIIHADNSISITDNGRGVPTGLKMDDKHDPKRSAAEIVMTELHAGGKFDQNS CCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC YKVSGGLHGVGVSCVNALSAWLRLTIRRDGKKHFMEFHRGVPQNRIIEEIDGVAVSPIQV EEECCCCCCHHHHHHHHHHHHHEEHHHCCCHHHHHHHHCCCCHHHHHHHHCCCEECCEEE TGETENRGTEVHFLADETIFGNIEYHYDILAKRIRELSFLNNGVRIKLTDQRTGKEEDFA ECCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEE FVGGVKGFVEYINKNKSVLHPNIFHISGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRD EECHHHHHHHHHCCCCCEECCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCC GGTHLTGLRAAMTRVLNKYINDHEVAKKAKVETSGDDMREGLSCVLSVKVPEPKFSAQTK CCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCCCCCHHH DKLVSSEVRAPVEDVVAKALEEFLLETPNDAKIICSKIVDAARARDAARKAREMTRRKGV HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC LDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCEEECHHHH YDKLLSSEQIVTLITALGCGIGKEDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQ HHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHH MPEMIERGYIYIAQPPLFKIKAGKDERYLKDEAEVNAHILKLALQGSELLASEGATPITG HHHHHHCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCCCH DALGELARAYLLAQAVVNRLSRLYDAGALEAVMDGVVVDLSSEEAAEVSAAALEAKLRDD HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHC ALKPEVKVTTMYDPVRELRSLRVARTHHGNQKISVLDQDFQLTADYQQLINTANTFKGLI CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHHHHHH GTGAVIKRGERSMAVTDFKSAMKWLLADAERNISKQRYKGLGEMNPGQLWETTMDPTVRR CCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH LLRVQIEDAIAADGIFTTLMGDDVEPRRAFIESNALRAGNIDV HHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCC >Mature Secondary Structure TETNNSQPDNSYGASSIQILEGLEAVRKRPGMYIGDTSDGTGLHHLVFEVLDNSIDEAL CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH AGHCNDIQVIIHADNSISITDNGRGVPTGLKMDDKHDPKRSAAEIVMTELHAGGKFDQNS CCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC YKVSGGLHGVGVSCVNALSAWLRLTIRRDGKKHFMEFHRGVPQNRIIEEIDGVAVSPIQV EEECCCCCCHHHHHHHHHHHHHEEHHHCCCHHHHHHHHCCCCHHHHHHHHCCCEECCEEE TGETENRGTEVHFLADETIFGNIEYHYDILAKRIRELSFLNNGVRIKLTDQRTGKEEDFA ECCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEE FVGGVKGFVEYINKNKSVLHPNIFHISGEKDGVGVEVAMQWNDSYNENVLCFTNNIPQRD EECHHHHHHHHHCCCCCEECCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCC GGTHLTGLRAAMTRVLNKYINDHEVAKKAKVETSGDDMREGLSCVLSVKVPEPKFSAQTK CCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHCEEEEEEECCCCCCCCHHH DKLVSSEVRAPVEDVVAKALEEFLLETPNDAKIICSKIVDAARARDAARKAREMTRRKGV HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC LDGVGLPGKLADCQEKDPAKSEIYIVEGDSAGGSAKQGRDRKFQAILPLRGKVLNVEKAR CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCEEECHHHH YDKLLSSEQIVTLITALGCGIGKEDYNLDKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQ HHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHH MPEMIERGYIYIAQPPLFKIKAGKDERYLKDEAEVNAHILKLALQGSELLASEGATPITG HHHHHHCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCCCH DALGELARAYLLAQAVVNRLSRLYDAGALEAVMDGVVVDLSSEEAAEVSAAALEAKLRDD HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHC ALKPEVKVTTMYDPVRELRSLRVARTHHGNQKISVLDQDFQLTADYQQLINTANTFKGLI CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECHHHHHHHHHHHHHHHHH GTGAVIKRGERSMAVTDFKSAMKWLLADAERNISKQRYKGLGEMNPGQLWETTMDPTVRR CCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH LLRVQIEDAIAADGIFTTLMGDDVEPRRAFIESNALRAGNIDV HHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1906260 [H]