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The map label for this gene is rocF [H]

Identifier: 91790432

GI number: 91790432

Start: 4883246

End: 4884160

Strand: Direct

Name: rocF [H]

Synonym: Bpro_4603

Alternate gene names: 91790432

Gene position: 4883246-4884160 (Clockwise)

Preceding gene: 91790431

Following gene: 91790439

Centisome position: 93.9

GC content: 66.01

Gene sequence:

>915_bases
ATGACCAGACGCATCCGGCTGATTGGCGCCCCGACCGACATTGGCGCCAGTACCCGAGGCTCGTCCATGGGCCCAGAAGC
GCTGCGCGTCGCGGGACTGCAGGCAACGCTGGAAGGCCACGGCCTGACCGTCGCGGACCAGGGCAATCTGGTGGGACCGG
CCAACCCCTGGCAAGCATCCGTTAACGGCTACCGCCACCTGGCCGAAGTGGCTGCGTGGAACCGTTCGGTGCATGAGGCC
GTGCATACCGCGCTCAGCGAAAACGACATGCCGATTTTGCTGGGAGGCGACCATTGCCTGGCCATTGGCTCCATCAGCGC
GGTGGCGCGCCACTGCCGCAAGACCGGTCAGAACCTGCGCGTGCTGTGGCTGGACGCCCATGCCGACTTCAACACCAACG
ACCTGACGCCCACCGGCAACACGCACGGCATGCCGGTGGCCGTGCTGTGCGGCCACGGGCCTGCCGAGCTGACCGGCATA
GGCGGCGTGGTGCCCGCCATCCAGCCCTCGGCCGTGCGGCAGATCGGCATCCGCAGCGTGGACCAGGGCGAAAAGCGCTT
TGTCCGGGAATTGGGCCTCGAAGTGTTCGACATGCGTTACATCGACGAAATGGGCATGCGCCACACCATGCAGGCGGCAC
TGGCCGGCATGGACGACAACACCCACCTGCATGTGAGTTTTGATGTCGACTTTCTGGACGCCTCGTTTGCGCCCGGTGTG
GGCACCGCCGTCAAGGGTGGGCCGACCTACCGCGAGGCCCAGCTGTGCATGGAGATGATTGCCGACACCGGCCGGCTGGC
ATCGCTGGATGTGATGGAGCTCAACCCGGCGCTGGATGTGCGCAACGGCACGGCCGAAGTGGCACTGGACCTGATGGAAA
GCCTGTTCGGCAAGAGCACGCTGATGCGGCGCTAG

Upstream 100 bases:

>100_bases
ATCCGAAAAACCTGTTTGGCCTGTTGGCAGCCGCCCCCGGGGGCACAACCCAGGCGGCCCCGGGACTGGTCAAACCCTTC
GCTGCCGAATTGACCTCGAC

Downstream 100 bases:

>100_bases
TGCGAAGGGCCGGCGCCCGGTAGCGCCTAGATTTCCGTCACGGCCGCCAGGCGGCGCAGGACCTGCTGGACGATGTCGCT
TTGCATGTCGCGGTAAAGCA

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTRRIRLIGAPTDIGASTRGSSMGPEALRVAGLQATLEGHGLTVADQGNLVGPANPWQASVNGYRHLAEVAAWNRSVHEA
VHTALSENDMPILLGGDHCLAIGSISAVARHCRKTGQNLRVLWLDAHADFNTNDLTPTGNTHGMPVAVLCGHGPAELTGI
GGVVPAIQPSAVRQIGIRSVDQGEKRFVRELGLEVFDMRYIDEMGMRHTMQAALAGMDDNTHLHVSFDVDFLDASFAPGV
GTAVKGGPTYREAQLCMEMIADTGRLASLDVMELNPALDVRNGTAEVALDLMESLFGKSTLMRR

Sequences:

>Translated_304_residues
MTRRIRLIGAPTDIGASTRGSSMGPEALRVAGLQATLEGHGLTVADQGNLVGPANPWQASVNGYRHLAEVAAWNRSVHEA
VHTALSENDMPILLGGDHCLAIGSISAVARHCRKTGQNLRVLWLDAHADFNTNDLTPTGNTHGMPVAVLCGHGPAELTGI
GGVVPAIQPSAVRQIGIRSVDQGEKRFVRELGLEVFDMRYIDEMGMRHTMQAALAGMDDNTHLHVSFDVDFLDASFAPGV
GTAVKGGPTYREAQLCMEMIADTGRLASLDVMELNPALDVRNGTAEVALDLMESLFGKSTLMRR
>Mature_303_residues
TRRIRLIGAPTDIGASTRGSSMGPEALRVAGLQATLEGHGLTVADQGNLVGPANPWQASVNGYRHLAEVAAWNRSVHEAV
HTALSENDMPILLGGDHCLAIGSISAVARHCRKTGQNLRVLWLDAHADFNTNDLTPTGNTHGMPVAVLCGHGPAELTGIG
GVVPAIQPSAVRQIGIRSVDQGEKRFVRELGLEVFDMRYIDEMGMRHTMQAALAGMDDNTHLHVSFDVDFLDASFAPGVG
TAVKGGPTYREAQLCMEMIADTGRLASLDVMELNPALDVRNGTAEVALDLMESLFGKSTLMRR

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=305, Percent_Identity=36.3934426229508, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI10947139, Length=283, Percent_Identity=37.8091872791519, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI71996843, Length=241, Percent_Identity=32.7800829875519, Blast_Score=118, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6325146, Length=305, Percent_Identity=32.4590163934426, Blast_Score=161, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24638886, Length=305, Percent_Identity=33.7704918032787, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32464; Mature: 32333

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRIRLIGAPTDIGASTRGSSMGPEALRVAGLQATLEGHGLTVADQGNLVGPANPWQAS
CCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCEEEECCCCCCCCCCCCHHH
VNGYRHLAEVAAWNRSVHEAVHTALSENDMPILLGGDHCLAIGSISAVARHCRKTGQNLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHHCCCCEE
VLWLDAHADFNTNDLTPTGNTHGMPVAVLCGHGPAELTGIGGVVPAIQPSAVRQIGIRSV
EEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHCCCCCCCCCCCCHHHHHHHCCCCC
DQGEKRFVRELGLEVFDMRYIDEMGMRHTMQAALAGMDDNTHLHVSFDVDFLDASFAPGV
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCC
GTAVKGGPTYREAQLCMEMIADTGRLASLDVMELNPALDVRNGTAEVALDLMESLFGKST
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCHHH
LMRR
HCCC
>Mature Secondary Structure 
TRRIRLIGAPTDIGASTRGSSMGPEALRVAGLQATLEGHGLTVADQGNLVGPANPWQAS
CCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCEEEECCCCCCCCCCCCHHH
VNGYRHLAEVAAWNRSVHEAVHTALSENDMPILLGGDHCLAIGSISAVARHCRKTGQNLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHHCCCCEE
VLWLDAHADFNTNDLTPTGNTHGMPVAVLCGHGPAELTGIGGVVPAIQPSAVRQIGIRSV
EEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHCCCCCCCCCCCCHHHHHHHCCCCC
DQGEKRFVRELGLEVFDMRYIDEMGMRHTMQAALAGMDDNTHLHVSFDVDFLDASFAPGV
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCC
GTAVKGGPTYREAQLCMEMIADTGRLASLDVMELNPALDVRNGTAEVALDLMESLFGKST
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCHHHHHHHHHHHHHCHHH
LMRR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]