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The map label for this gene is narQ [H]

Identifier: 91790428

GI number: 91790428

Start: 4876063

End: 4877976

Strand: Reverse

Name: narQ [H]

Synonym: Bpro_4599

Alternate gene names: 91790428

Gene position: 4877976-4876063 (Counterclockwise)

Preceding gene: 91790429

Following gene: 91790427

Centisome position: 93.8

GC content: 66.56

Gene sequence:

>1914_bases
ATGCAGCACACGGCCTCGCTCTCCAAAAAACTCGTTCGCATAGGCGCCAGCCTGCTGGTCGTTTCGCTGATCTCCATCGG
GCTGACCCTTTGGGTGACGTGGCAGCTCGAGGGAGGCGCAGCGGCCGTCAATGAGGCCGGGCGCATGCGCATGCAGACCT
GGCGGCTGGTCAGCGCGGTGCAGGCCGGCGTGGAGCGCGCCGAGCTGCAGGGCCTCGTGGTCCGGTTCGATGAGAGTCTG
GCCGTGCTGCGCGAGGGGGACCCTTCCAGGCCGCTGTTCGTGCCCTGGGACGACCAGGTGCGCCAGCGTTTTGCCGAAGT
CGAGTCCCTGTGGCGCGATCAGCGGCCGTTGTGGCTGGCCGAACCGGCTCCGCAGGTGCAGGTCCTGCAGAAGGCCGGGG
AGGAGTTTGTGGCGGCCAGCGACCGCCTGGTGCTGGTGATCGAGCAGCACCAGTCCCGGCTGACCGCCATCCTGAACCTG
TTTCAGCTCCTGCTGCTGGCACTGGCCATTGGTGGGGCGGTCATCATGCTCTATACCGGGTACATGTATGTGATCAACCC
CCTGGGGCAGCTTCGCCAGGGCTTGCGCAAGCTGGAGTCCGGGGATTTCAGGACGCGTATCGAGGTCGACACCGTGGACG
AGTTTGGCCAGGTAGCGGCCGGCTTCAACCACATGGCGGCGACCCTGCAGTCGCTCTATGAAGGGCTGGAAGCCAAGGTC
GAGGCCAAGACGCGGCGCATCGAGGCGCAACACGCCCGGCTCGAGGCGCTCTACAAGGTCAGCGCATTTCTGGCCCAGGC
CGGGAGCATTGACGAGCTGGCGCGCGGGTTTGCCCAGCGCGTGCGCGCCGTGATGAAGGCCGACGCGGCAGCGGTCCGCT
GGTCTGACGATGCCAACCAGCGTTACCTGATGCTGGCTTCCGACTGCTTTCCGCAGGACCTGGTGGAGGAAGAGCGCAGC
CTGCTGGCCGGGGCCTGTGCCTGCGGCAACCTGCGGCCGGACGCGCGCACCCGCGTGATTCCGATTCTCAGCCACGACGA
AGCGCCCGTTCGCCATTGCGCCAAGGTGGGCTACGAAAGCGTGGTCAGCGTGCCGATACGGCTGCAGCAGCGCCTGCTCG
GCGAGTTCAACCTGTTCTTTCGCGCGCCTGTCCTGCTGAGCGCCGACGAAATCGAACTGCTGGATGCGCTGGCCAGCCAC
CTGGCCAGTTCGCTGGAAGGTTTGCGCGCCGACGCCCTGGACCGGGAGGCGGCGGTTGCGGAGGAGCGCGCGCTGCTGGC
GCGCAACCTGCATGACTCGATTGCGCAGTCGCTGGCATTTCTCAAGATCCAGGTGCAGCTGCTGCGGACAGCCGTGCAGA
AGGGGCAGGAGCCCCAGGTGCAGGGCGCACTCGACGAACTGGACCTCGGGCTGCGCGAAAGCATTGGCGACGTTCGCGAA
CTGCTGGTGCATTTCCGCACGCGCACCAACACCGACGACATCGAGCAGGCGCTGCAGGAAACGCTGCAGAAATTCCAGAG
CCAGACAGCTTTGCCTGCACAGCTGCAGGTCCAGGGTCAGGGTCTCCCGCTGCCGTCCGACGTTCAGGTGCAGGTGCTGC
ACGTGGTGCAGGAGGCGCTGTCCAATGTGCGCAAGCATGCCGGCGCCACGCAGGTCGACCTGGAAGTGGCCAAGGGCGCG
CGCTGGCGTTTTGTGGTGCGCGACAACGGTGCCGGTTTCGATACCGGAAAGCACCCGGGAGAGTCGCATGTCGGCCTCAA
CATCATGCGCGAGCGTGCCGGGCGCATCGGTGCCGAGGTGGACATTGTCTCCACGGCGGGTCAGGGAACCACGGTGACGC
TGACACTGCCGCCGCATCCGGAGGTGAGCGGCGGTGTGGCGACGAAGATACCGGATCCGGCACCCGCCGACTGA

Upstream 100 bases:

>100_bases
CTGCACCGGCTGGCCGGCATGGTCTGCCGGGAGTGCGCGGCACCGTCCGCTGCGCCTCGCGGGTTGCGCAATCCGGTGGA
GATCGCACGGGGCTAGAGGC

Downstream 100 bases:

>100_bases
GGAATGAACACGATGAAAGCTGTTGAATTGCTGGTAGTCGACGACCACACCCTGTTTCGCCGCGGACTCGTTGCGCTGCT
GTCGCAGGATGGGCGCTTCG

Product: signal transduction histidine kinase, nitrate/nitrite-specific, NarQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MQHTASLSKKLVRIGASLLVVSLISIGLTLWVTWQLEGGAAAVNEAGRMRMQTWRLVSAVQAGVERAELQGLVVRFDESL
AVLREGDPSRPLFVPWDDQVRQRFAEVESLWRDQRPLWLAEPAPQVQVLQKAGEEFVAASDRLVLVIEQHQSRLTAILNL
FQLLLLALAIGGAVIMLYTGYMYVINPLGQLRQGLRKLESGDFRTRIEVDTVDEFGQVAAGFNHMAATLQSLYEGLEAKV
EAKTRRIEAQHARLEALYKVSAFLAQAGSIDELARGFAQRVRAVMKADAAAVRWSDDANQRYLMLASDCFPQDLVEEERS
LLAGACACGNLRPDARTRVIPILSHDEAPVRHCAKVGYESVVSVPIRLQQRLLGEFNLFFRAPVLLSADEIELLDALASH
LASSLEGLRADALDREAAVAEERALLARNLHDSIAQSLAFLKIQVQLLRTAVQKGQEPQVQGALDELDLGLRESIGDVRE
LLVHFRTRTNTDDIEQALQETLQKFQSQTALPAQLQVQGQGLPLPSDVQVQVLHVVQEALSNVRKHAGATQVDLEVAKGA
RWRFVVRDNGAGFDTGKHPGESHVGLNIMRERAGRIGAEVDIVSTAGQGTTVTLTLPPHPEVSGGVATKIPDPAPAD

Sequences:

>Translated_637_residues
MQHTASLSKKLVRIGASLLVVSLISIGLTLWVTWQLEGGAAAVNEAGRMRMQTWRLVSAVQAGVERAELQGLVVRFDESL
AVLREGDPSRPLFVPWDDQVRQRFAEVESLWRDQRPLWLAEPAPQVQVLQKAGEEFVAASDRLVLVIEQHQSRLTAILNL
FQLLLLALAIGGAVIMLYTGYMYVINPLGQLRQGLRKLESGDFRTRIEVDTVDEFGQVAAGFNHMAATLQSLYEGLEAKV
EAKTRRIEAQHARLEALYKVSAFLAQAGSIDELARGFAQRVRAVMKADAAAVRWSDDANQRYLMLASDCFPQDLVEEERS
LLAGACACGNLRPDARTRVIPILSHDEAPVRHCAKVGYESVVSVPIRLQQRLLGEFNLFFRAPVLLSADEIELLDALASH
LASSLEGLRADALDREAAVAEERALLARNLHDSIAQSLAFLKIQVQLLRTAVQKGQEPQVQGALDELDLGLRESIGDVRE
LLVHFRTRTNTDDIEQALQETLQKFQSQTALPAQLQVQGQGLPLPSDVQVQVLHVVQEALSNVRKHAGATQVDLEVAKGA
RWRFVVRDNGAGFDTGKHPGESHVGLNIMRERAGRIGAEVDIVSTAGQGTTVTLTLPPHPEVSGGVATKIPDPAPAD
>Mature_637_residues
MQHTASLSKKLVRIGASLLVVSLISIGLTLWVTWQLEGGAAAVNEAGRMRMQTWRLVSAVQAGVERAELQGLVVRFDESL
AVLREGDPSRPLFVPWDDQVRQRFAEVESLWRDQRPLWLAEPAPQVQVLQKAGEEFVAASDRLVLVIEQHQSRLTAILNL
FQLLLLALAIGGAVIMLYTGYMYVINPLGQLRQGLRKLESGDFRTRIEVDTVDEFGQVAAGFNHMAATLQSLYEGLEAKV
EAKTRRIEAQHARLEALYKVSAFLAQAGSIDELARGFAQRVRAVMKADAAAVRWSDDANQRYLMLASDCFPQDLVEEERS
LLAGACACGNLRPDARTRVIPILSHDEAPVRHCAKVGYESVVSVPIRLQQRLLGEFNLFFRAPVLLSADEIELLDALASH
LASSLEGLRADALDREAAVAEERALLARNLHDSIAQSLAFLKIQVQLLRTAVQKGQEPQVQGALDELDLGLRESIGDVRE
LLVHFRTRTNTDDIEQALQETLQKFQSQTALPAQLQVQGQGLPLPSDVQVQVLHVVQEALSNVRKHAGATQVDLEVAKGA
RWRFVVRDNGAGFDTGKHPGESHVGLNIMRERAGRIGAEVDIVSTAGQGTTVTLTLPPHPEVSGGVATKIPDPAPAD

Specific function: Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the narL/narP proteins. NarQ probably activates narL and narP by phosphorylation. NarQ probably negatively regulates the narL protein by dephosphorylation [H]

COG id: COG3850

COG function: function code T; Signal transduction histidine kinase, nitrate/nitrite-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=623, Percent_Identity=27.4478330658106, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1787474, Length=235, Percent_Identity=32.3404255319149, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR016380
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69850; Mature: 69850

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHTASLSKKLVRIGASLLVVSLISIGLTLWVTWQLEGGAAAVNEAGRMRMQTWRLVSAV
CCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
QAGVERAELQGLVVRFDESLAVLREGDPSRPLFVPWDDQVRQRFAEVESLWRDQRPLWLA
HHHHHHHHHHHHHEEECCHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEE
EPAPQVQVLQKAGEEFVAASDRLVLVIEQHQSRLTAILNLFQLLLLALAIGGAVIMLYTG
CCCHHHHHHHHCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMYVINPLGQLRQGLRKLESGDFRTRIEVDTVDEFGQVAAGFNHMAATLQSLYEGLEAKV
HHHHHCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKTRRIEAQHARLEALYKVSAFLAQAGSIDELARGFAQRVRAVMKADAAAVRWSDDANQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHEEEECCCCCC
RYLMLASDCFPQDLVEEERSLLAGACACGNLRPDARTRVIPILSHDEAPVRHCAKVGYES
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCHHH
VVSVPIRLQQRLLGEFNLFFRAPVLLSADEIELLDALASHLASSLEGLRADALDREAAVA
HHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EERALLARNLHDSIAQSLAFLKIQVQLLRTAVQKGQEPQVQGALDELDLGLRESIGDVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHCCCHHHHHHHHHH
LLVHFRTRTNTDDIEQALQETLQKFQSQTALPAQLQVQGQGLPLPSDVQVQVLHVVQEAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
SNVRKHAGATQVDLEVAKGARWRFVVRDNGAGFDTGKHPGESHVGLNIMRERAGRIGAEV
HHHHHHCCCCEEEHEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEE
DIVSTAGQGTTVTLTLPPHPEVSGGVATKIPDPAPAD
EEEEECCCCEEEEEEECCCCCCCCCEECCCCCCCCCC
>Mature Secondary Structure
MQHTASLSKKLVRIGASLLVVSLISIGLTLWVTWQLEGGAAAVNEAGRMRMQTWRLVSAV
CCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
QAGVERAELQGLVVRFDESLAVLREGDPSRPLFVPWDDQVRQRFAEVESLWRDQRPLWLA
HHHHHHHHHHHHHEEECCHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEE
EPAPQVQVLQKAGEEFVAASDRLVLVIEQHQSRLTAILNLFQLLLLALAIGGAVIMLYTG
CCCHHHHHHHHCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YMYVINPLGQLRQGLRKLESGDFRTRIEVDTVDEFGQVAAGFNHMAATLQSLYEGLEAKV
HHHHHCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKTRRIEAQHARLEALYKVSAFLAQAGSIDELARGFAQRVRAVMKADAAAVRWSDDANQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHEEEECCCCCC
RYLMLASDCFPQDLVEEERSLLAGACACGNLRPDARTRVIPILSHDEAPVRHCAKVGYES
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCHHH
VVSVPIRLQQRLLGEFNLFFRAPVLLSADEIELLDALASHLASSLEGLRADALDREAAVA
HHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EERALLARNLHDSIAQSLAFLKIQVQLLRTAVQKGQEPQVQGALDELDLGLRESIGDVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHCCCHHHHHHHHHH
LLVHFRTRTNTDDIEQALQETLQKFQSQTALPAQLQVQGQGLPLPSDVQVQVLHVVQEAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
SNVRKHAGATQVDLEVAKGARWRFVVRDNGAGFDTGKHPGESHVGLNIMRERAGRIGAEV
HHHHHHCCCCEEEHEECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEE
DIVSTAGQGTTVTLTLPPHPEVSGGVATKIPDPAPAD
EEEEECCCCEEEEEEECCCCCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1528845; 1508040; 9205837; 9278503 [H]