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The map label for this gene is degU [H]

Identifier: 91790427

GI number: 91790427

Start: 4875340

End: 4876050

Strand: Reverse

Name: degU [H]

Synonym: Bpro_4598

Alternate gene names: 91790427

Gene position: 4876050-4875340 (Counterclockwise)

Preceding gene: 91790428

Following gene: 91790426

Centisome position: 93.77

GC content: 63.99

Gene sequence:

>711_bases
ATGAAAGCTGTTGAATTGCTGGTAGTCGACGACCACACCCTGTTTCGCCGCGGACTCGTTGCGCTGCTGTCGCAGGATGG
GCGCTTCGAAGTCGCTGGCGAGGCCGGCGATATCGGCGAGGCGCTGCGTTGCGTGGAGCGCAGCAAGCCGGACCTGATCC
TGCTGGACAACCACCTGCCGGGCGTTCTTGGCGTGGATGGCATCGCAGCGCTCAAGGACGCGGCCCCGGGCACCCGCATC
CTGATGTTGACCGTCAGCGAAAACGAGGACGATCTGGCTGCGGCGCTGCAGGCCGGCGCTGACGGCTATCTGCTGAAAAC
CGTGGAACTCGACAGCCTGTCCGAATCCATCATCAAGGTCCTGGACGGTGAATCCGTTGTCAGTCCGGAAATGATGACCA
AGCTGGTGGCCGCCTTCCGGTCCCGGGCGCTGTCGTCTGCAACCGGCGAGACCGCAGCGAACGAGGAAGGCCACGACGAG
GCAGCACCGGTACCGGGCAGGCAGGACGATTCGGCCATTGCGCTGCTTTCGGCGCGTGAGCGCGAGGTTCTGGCCCGGAT
CTCGCACGGTGACAGCAACAAGGTGATTGCGCGCAAGCTCGACATCGCGGAGACCACGGTGAAGATTCACGTGCAGCACA
TTCTGCGCAAGCTTCAGCTCAGTTCGCGGGTGCAGGCCGCCGTATACGCGGCCGCCCATGACCTGGGTTGA

Upstream 100 bases:

>100_bases
AACCACGGTGACGCTGACACTGCCGCCGCATCCGGAGGTGAGCGGCGGTGTGGCGACGAAGATACCGGATCCGGCACCCG
CCGACTGAGGAATGAACACG

Downstream 100 bases:

>100_bases
CAAAGATCAACGCCGGGGCTGATTGATCCGGCAGTAGTTCTTCAGAACGATGGCGGCCCGGCCGCCATCGCCTTTTCTGC
CTGATCTGCACGTTCCAAAG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKAVELLVVDDHTLFRRGLVALLSQDGRFEVAGEAGDIGEALRCVERSKPDLILLDNHLPGVLGVDGIAALKDAAPGTRI
LMLTVSENEDDLAAALQAGADGYLLKTVELDSLSESIIKVLDGESVVSPEMMTKLVAAFRSRALSSATGETAANEEGHDE
AAPVPGRQDDSAIALLSAREREVLARISHGDSNKVIARKLDIAETTVKIHVQHILRKLQLSSRVQAAVYAAAHDLG

Sequences:

>Translated_236_residues
MKAVELLVVDDHTLFRRGLVALLSQDGRFEVAGEAGDIGEALRCVERSKPDLILLDNHLPGVLGVDGIAALKDAAPGTRI
LMLTVSENEDDLAAALQAGADGYLLKTVELDSLSESIIKVLDGESVVSPEMMTKLVAAFRSRALSSATGETAANEEGHDE
AAPVPGRQDDSAIALLSAREREVLARISHGDSNKVIARKLDIAETTVKIHVQHILRKLQLSSRVQAAVYAAAHDLG
>Mature_236_residues
MKAVELLVVDDHTLFRRGLVALLSQDGRFEVAGEAGDIGEALRCVERSKPDLILLDNHLPGVLGVDGIAALKDAAPGTRI
LMLTVSENEDDLAAALQAGADGYLLKTVELDSLSESIIKVLDGESVVSPEMMTKLVAAFRSRALSSATGETAANEEGHDE
AAPVPGRQDDSAIALLSAREREVLARISHGDSNKVIARKLDIAETTVKIHVQHILRKLQLSSRVQAAVYAAAHDLG

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=224, Percent_Identity=36.1607142857143, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1787473, Length=224, Percent_Identity=37.5, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788222, Length=232, Percent_Identity=25.4310344827586, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786747, Length=237, Percent_Identity=26.1603375527426, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25084; Mature: 25084

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVELLVVDDHTLFRRGLVALLSQDGRFEVAGEAGDIGEALRCVERSKPDLILLDNHLP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEECCCCC
GVLGVDGIAALKDAAPGTRILMLTVSENEDDLAAALQAGADGYLLKTVELDSLSESIIKV
CCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHH
LDGESVVSPEMMTKLVAAFRSRALSSATGETAANEEGHDEAAPVPGRQDDSAIALLSARE
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHH
REVLARISHGDSNKVIARKLDIAETTVKIHVQHILRKLQLSSRVQAAVYAAAHDLG
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAVELLVVDDHTLFRRGLVALLSQDGRFEVAGEAGDIGEALRCVERSKPDLILLDNHLP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEECCCCC
GVLGVDGIAALKDAAPGTRILMLTVSENEDDLAAALQAGADGYLLKTVELDSLSESIIKV
CCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHH
LDGESVVSPEMMTKLVAAFRSRALSSATGETAANEEGHDEAAPVPGRQDDSAIALLSARE
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHH
REVLARISHGDSNKVIARKLDIAETTVKIHVQHILRKLQLSSRVQAAVYAAAHDLG
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]