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The map label for this gene is betA [C]

Identifier: 91790354

GI number: 91790354

Start: 4780563

End: 4782125

Strand: Direct

Name: betA [C]

Synonym: Bpro_4522

Alternate gene names: 91790354

Gene position: 4780563-4782125 (Clockwise)

Preceding gene: 91790353

Following gene: 91790357

Centisome position: 91.93

GC content: 62.44

Gene sequence:

>1563_bases
ATGAAAAAATCCATTCCCGTGAAGCTCGCCAAGCAGGGCCTCAAGGTCACGCAGGCCGGTGACATCACGCAGGAAAAACT
GCACCTGAAGGCCGATGCGGTGATCATCGGTTCGGGCGCTGGCGGGGCCATCGCCGCCTACGAACTGGCGCGCGCGGGCA
AGACGGTCATCGTGCTGGAGGCCGGTCCGTACATCCCGTCGGAGAAGTTCACCGAGATGCTGGCCGTCTCGATGGGAACG
CTCTACCAGGACCACGGCGGGCAGTCCAACATGCATGGCGATATTGCCATCCTGCAAGGCGCCTGTGTTGGCGGCTCCAC
GGTGGTCAATGCGGCGCTGTGCTTTCGCACGCCCGATTACTACCTGAAGCTGTGGGCCAAAGAGTTCGGCCTGAGCAACC
TCACCAAGGCGGTGATGACGCCGTACTTTGAGAAGATAGAGCGCAACCTGCACATCCGCACCGTCGCCTCGCACGAGACC
AGCCCCGGCGCGGAACTCATCGGCATTGGCATGCGCAAGCTCGGCTACCCGCCAGGCAAGGCGCGGCGCAACATCAAGGA
CTGCGCACTCACCGGCGCCTGTTTCAGCGGCTGCACTTCCGACCGCAAGCAATCCATGCTGGTGACCTACCTGCCCTGGG
CCGTGGCGCATGGCGCGACCATCTTCGCCGACACGCGTGTCACGCAAGTGCTGGCCGAGGGTGGCAAGGCCAGTGGCGTG
CTGGCCGAGGTCATCGACCCGGCTACCGGAAAGAAGAAGGCCGATGTGCGCGTTGATGCCCCCATCGTCGTGCTGGCGGC
CGGGCCGATCCAGACGCCGCTGCTGCTGCTCAAAAGCGGGCTGGCCAATAGCAGCGCACAAGTGGGCAAGAACTTCGCCT
GCCACCCGACCTTGTCGGTCACCGCTGAATTTCCCCACGAGGTCAACGACTTCCACGGCGCCACCCACTCGCTTTATATG
GACCAGCACACACTGCCCGAGAAAGGCGGCTACCTGTTGCTCAACGCGATCCAGGAGCCGGTGGAGGCTGGCTTTCAGGC
CGAGCCCGGCACCGGCAAGCCCTACGTGGCCTACATGACGGGCTACAAAAATACGATCCGCCTGATCAGCCTGATCCACG
ACAAGAATGTAGGCGAGGTGCGCTGGGAGAACGGTCAGAAGCAGATCCATTACACGGTAGACAACGATGACTTCGATGCG
ATGAAGAAAGGGCTGGTCGCCACGGCGCGCATTTTGTTTGCCTCCGGGGCGAGCAAGCTTTACCTGCCGTCATCCAACAA
GGCGGTGGTCGAGAGCGCCGATCAGGTGGAAAGCGTGATCGGCGCGTTGAAGAACGAACCGGCACGCTACAAATACACCT
CCTTCCATCCGCAGGGCACCTGCCGCATGGGGCGCAACCCGAAGACCACCGTAGTCAACCCCTACGGCGAAACGCACGAC
GTGAAAAACCTGTACGTGGCCGACGCCAGCCTGCTGCCGACCTCGATCGGCTACAACCCCTCGGAGACGGTGTACGCACT
GGCAAGCTACATCAGCGACCGCATCGTCAAGGCGCACGCGTAA

Upstream 100 bases:

>100_bases
TTGGGTTACGACGGACCAATGACCAAGCGCCTGGGCCTGAAGTCCCTGGGCAACGCACCGCTGCCGACACGCTGAACATC
ACCATTCGAGGACACACCAC

Downstream 100 bases:

>100_bases
GCATCTGTTGTGACTCTACTTTTCGTTACTGCCTGCACCATGACGTGCTCATCGAAGCGCAGGTCAATGCAACTTTTGAA
TGCATGGCGGCTGTGTTGGA

Product: glucose-methanol-choline oxidoreductase

Products: Betaine Aldehyde; Reduced Acceptor. [C]

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKKSIPVKLAKQGLKVTQAGDITQEKLHLKADAVIIGSGAGGAIAAYELARAGKTVIVLEAGPYIPSEKFTEMLAVSMGT
LYQDHGGQSNMHGDIAILQGACVGGSTVVNAALCFRTPDYYLKLWAKEFGLSNLTKAVMTPYFEKIERNLHIRTVASHET
SPGAELIGIGMRKLGYPPGKARRNIKDCALTGACFSGCTSDRKQSMLVTYLPWAVAHGATIFADTRVTQVLAEGGKASGV
LAEVIDPATGKKKADVRVDAPIVVLAAGPIQTPLLLLKSGLANSSAQVGKNFACHPTLSVTAEFPHEVNDFHGATHSLYM
DQHTLPEKGGYLLLNAIQEPVEAGFQAEPGTGKPYVAYMTGYKNTIRLISLIHDKNVGEVRWENGQKQIHYTVDNDDFDA
MKKGLVATARILFASGASKLYLPSSNKAVVESADQVESVIGALKNEPARYKYTSFHPQGTCRMGRNPKTTVVNPYGETHD
VKNLYVADASLLPTSIGYNPSETVYALASYISDRIVKAHA

Sequences:

>Translated_520_residues
MKKSIPVKLAKQGLKVTQAGDITQEKLHLKADAVIIGSGAGGAIAAYELARAGKTVIVLEAGPYIPSEKFTEMLAVSMGT
LYQDHGGQSNMHGDIAILQGACVGGSTVVNAALCFRTPDYYLKLWAKEFGLSNLTKAVMTPYFEKIERNLHIRTVASHET
SPGAELIGIGMRKLGYPPGKARRNIKDCALTGACFSGCTSDRKQSMLVTYLPWAVAHGATIFADTRVTQVLAEGGKASGV
LAEVIDPATGKKKADVRVDAPIVVLAAGPIQTPLLLLKSGLANSSAQVGKNFACHPTLSVTAEFPHEVNDFHGATHSLYM
DQHTLPEKGGYLLLNAIQEPVEAGFQAEPGTGKPYVAYMTGYKNTIRLISLIHDKNVGEVRWENGQKQIHYTVDNDDFDA
MKKGLVATARILFASGASKLYLPSSNKAVVESADQVESVIGALKNEPARYKYTSFHPQGTCRMGRNPKTTVVNPYGETHD
VKNLYVADASLLPTSIGYNPSETVYALASYISDRIVKAHA
>Mature_520_residues
MKKSIPVKLAKQGLKVTQAGDITQEKLHLKADAVIIGSGAGGAIAAYELARAGKTVIVLEAGPYIPSEKFTEMLAVSMGT
LYQDHGGQSNMHGDIAILQGACVGGSTVVNAALCFRTPDYYLKLWAKEFGLSNLTKAVMTPYFEKIERNLHIRTVASHET
SPGAELIGIGMRKLGYPPGKARRNIKDCALTGACFSGCTSDRKQSMLVTYLPWAVAHGATIFADTRVTQVLAEGGKASGV
LAEVIDPATGKKKADVRVDAPIVVLAAGPIQTPLLLLKSGLANSSAQVGKNFACHPTLSVTAEFPHEVNDFHGATHSLYM
DQHTLPEKGGYLLLNAIQEPVEAGFQAEPGTGKPYVAYMTGYKNTIRLISLIHDKNVGEVRWENGQKQIHYTVDNDDFDA
MKKGLVATARILFASGASKLYLPSSNKAVVESADQVESVIGALKNEPARYKYTSFHPQGTCRMGRNPKTTVVNPYGETHD
VKNLYVADASLLPTSIGYNPSETVYALASYISDRIVKAHA

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: 1.1.99.1 [C]

Molecular weight: Translated: 55808; Mature: 55808

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSIPVKLAKQGLKVTQAGDITQEKLHLKADAVIIGSGAGGAIAAYELARAGKTVIVLE
CCCCCCHHHHHCCCEEEECCCCCHHHEEEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
AGPYIPSEKFTEMLAVSMGTLYQDHGGQSNMHGDIAILQGACVGGSTVVNAALCFRTPDY
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHEECCCHH
YLKLWAKEFGLSNLTKAVMTPYFEKIERNLHIRTVASHETSPGAELIGIGMRKLGYPPGK
HHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCHHHCCCCCCH
ARRNIKDCALTGACFSGCTSDRKQSMLVTYLPWAVAHGATIFADTRVTQVLAEGGKASGV
HHCCHHHHHHHHHHHHCCCCCHHCCEEEEEHHHHHHCCCEEEEHHHHHHHHHCCCCCCCH
LAEVIDPATGKKKADVRVDAPIVVLAAGPIQTPLLLLKSGLANSSAQVGKNFACHPTLSV
HHHHHCCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHCCCCCCHHHCCCEECCCCEEE
TAEFPHEVNDFHGATHSLYMDQHTLPEKGGYLLLNAIQEPVEAGFQAEPGTGKPYVAYMT
EECCCCHHHHHCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCEEEEEC
GYKNTIRLISLIHDKNVGEVRWENGQKQIHYTVDNDDFDAMKKGLVATARILFASGASKL
CCCHHHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHEECCCCEE
YLPSSNKAVVESADQVESVIGALKNEPARYKYTSFHPQGTCRMGRNPKTTVVNPYGETHD
EECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEECCCCCCCC
VKNLYVADASLLPTSIGYNPSETVYALASYISDRIVKAHA
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKSIPVKLAKQGLKVTQAGDITQEKLHLKADAVIIGSGAGGAIAAYELARAGKTVIVLE
CCCCCCHHHHHCCCEEEECCCCCHHHEEEEEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
AGPYIPSEKFTEMLAVSMGTLYQDHGGQSNMHGDIAILQGACVGGSTVVNAALCFRTPDY
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHEECCCHH
YLKLWAKEFGLSNLTKAVMTPYFEKIERNLHIRTVASHETSPGAELIGIGMRKLGYPPGK
HHHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEECCHHHCCCCCCH
ARRNIKDCALTGACFSGCTSDRKQSMLVTYLPWAVAHGATIFADTRVTQVLAEGGKASGV
HHCCHHHHHHHHHHHHCCCCCHHCCEEEEEHHHHHHCCCEEEEHHHHHHHHHCCCCCCCH
LAEVIDPATGKKKADVRVDAPIVVLAAGPIQTPLLLLKSGLANSSAQVGKNFACHPTLSV
HHHHHCCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHCCCCCCHHHCCCEECCCCEEE
TAEFPHEVNDFHGATHSLYMDQHTLPEKGGYLLLNAIQEPVEAGFQAEPGTGKPYVAYMT
EECCCCHHHHHCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCEEEEEC
GYKNTIRLISLIHDKNVGEVRWENGQKQIHYTVDNDDFDAMKKGLVATARILFASGASKL
CCCHHHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHEECCCCEE
YLPSSNKAVVESADQVESVIGALKNEPARYKYTSFHPQGTCRMGRNPKTTVVNPYGETHD
EECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEECCCCCCCC
VKNLYVADASLLPTSIGYNPSETVYALASYISDRIVKAHA
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Coenzyme Q [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 7 {choline}} 1.1 {phenazine}} [C]

Substrates: Choline; Acceptor [C]

Specific reaction: Choline + Acceptor = Betaine Aldehyde + Reduced Acceptor. [C]

General reaction: Redox reaction [C]

Inhibitor: 2-Dimethylaminoethanol; Betaine aldehyde; Monoethanolamine; Semicarbazide [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]