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The map label for this gene is thiL [H]

Identifier: 91790304

GI number: 91790304

Start: 4727588

End: 4728586

Strand: Direct

Name: thiL [H]

Synonym: Bpro_4471

Alternate gene names: 91790304

Gene position: 4727588-4728586 (Clockwise)

Preceding gene: 91790303

Following gene: 91790306

Centisome position: 90.91

GC content: 68.87

Gene sequence:

>999_bases
ATGCTTGGCCCCATGGGTGAGTTTGATCTGATTGCACGCTACTTCACACGACCTGCACGCCGCGCCGTGCTTGGCGTGGG
CGACGACTGCGCGCTGCTGCAGCCTGCACCGGGCACGCAACTGGCCATTTCCTGCGACATGCTGGTCGAAGGCCGGCACT
TTTTCCCGGATGTCGATCCTTTCAGGCTGGGCCACAAGGCGCTGGCGGTCAACCTGAGCGACCTGGCCGCCTGCGGCGCG
ACGCCGCTGGCCTTCACGCTGGCGCTCGCGCTGCCGCGCGCCGACGACGCCTGGCTGGAGCCCTTTTCGCGCGGCCTGCT
GCGCCTGGCCGATGCGCACGGCTGCGAGCTGGTCGGCGGCGACACCACACAAGGGCCACTCAATATCTGCATCACGGTGT
TCGGCGAAGTGCCTGTGGTGGGCGGCAAGGGCCAGGCCCTGCTGCGCTCGGGCGCCAGGGCCGGGGACGACCTGTATGTG
AGCGGCACGCTGGGCGATGCGCGGCTGGCCCTCGAAGCCCTGCGCGGCGCCCTGCCGCTGCCCGCCGAGGCACTGGCGCA
GGCCCGCACCCGCCTGGAGCAGCCGACGCCCAGGGTAGCGCTGGGTCAGGCCTTGCGCGGCATCGCCAGCGCCGCCATCG
ATGTGAGCGACGGCCTGCTGGGCGACCTGCGCCACATCCTGGCGGCATCGCGGGTCGGCGCCACCATCCAGACCGAACTC
GCTACCAGTTTGATAGCCTCTGGCTCCCGTTCGGCAGGGGAAAGCGCCCACATTTCCGCGGATAAGCAGCTGGAACTCAT
ACTCTCGGGCGGAGACGATTACGAGCTGGCCTTCACAGCGCCCGCGTCCGCCCGTGACGCAGTGGAGGCGGCTTCACAGC
AGGCGCAAACGCCCGTCACACGCATCGGCAGCATCGAGACCGACCCCGGCCTGCGGCTGCTCAATGCCCAGGGGCAACTC
ATGCCCGGCAGGTTCGCTTCATTTGATCACTTTGCCTGA

Upstream 100 bases:

>100_bases
GGAGCGCCTGCTGGCCGAGGTCATCCGGCAGGCCGCCCAGCGCTTTCGCGGCGGCGTGACGCATACCCAGCTGCCCTGAC
CAGGCTGGCGTACTGCCTGT

Downstream 100 bases:

>100_bases
TACGGCAGCAGCCCTTATTGGCTCAAAAATAGCTGCCACCAGCCTCTCCGGGCAGCAAGCCAGCGCTACCGCGCCCCCGC
CTCGCAGTTACTTCGCATCC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLGPMGEFDLIARYFTRPARRAVLGVGDDCALLQPAPGTQLAISCDMLVEGRHFFPDVDPFRLGHKALAVNLSDLAACGA
TPLAFTLALALPRADDAWLEPFSRGLLRLADAHGCELVGGDTTQGPLNICITVFGEVPVVGGKGQALLRSGARAGDDLYV
SGTLGDARLALEALRGALPLPAEALAQARTRLEQPTPRVALGQALRGIASAAIDVSDGLLGDLRHILAASRVGATIQTEL
ATSLIASGSRSAGESAHISADKQLELILSGGDDYELAFTAPASARDAVEAASQQAQTPVTRIGSIETDPGLRLLNAQGQL
MPGRFASFDHFA

Sequences:

>Translated_332_residues
MLGPMGEFDLIARYFTRPARRAVLGVGDDCALLQPAPGTQLAISCDMLVEGRHFFPDVDPFRLGHKALAVNLSDLAACGA
TPLAFTLALALPRADDAWLEPFSRGLLRLADAHGCELVGGDTTQGPLNICITVFGEVPVVGGKGQALLRSGARAGDDLYV
SGTLGDARLALEALRGALPLPAEALAQARTRLEQPTPRVALGQALRGIASAAIDVSDGLLGDLRHILAASRVGATIQTEL
ATSLIASGSRSAGESAHISADKQLELILSGGDDYELAFTAPASARDAVEAASQQAQTPVTRIGSIETDPGLRLLNAQGQL
MPGRFASFDHFA
>Mature_332_residues
MLGPMGEFDLIARYFTRPARRAVLGVGDDCALLQPAPGTQLAISCDMLVEGRHFFPDVDPFRLGHKALAVNLSDLAACGA
TPLAFTLALALPRADDAWLEPFSRGLLRLADAHGCELVGGDTTQGPLNICITVFGEVPVVGGKGQALLRSGARAGDDLYV
SGTLGDARLALEALRGALPLPAEALAQARTRLEQPTPRVALGQALRGIASAAIDVSDGLLGDLRHILAASRVGATIQTEL
ATSLIASGSRSAGESAHISADKQLELILSGGDDYELAFTAPASARDAVEAASQQAQTPVTRIGSIETDPGLRLLNAQGQL
MPGRFASFDHFA

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=331, Percent_Identity=45.9214501510574, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34519; Mature: 34519

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGPMGEFDLIARYFTRPARRAVLGVGDDCALLQPAPGTQLAISCDMLVEGRHFFPDVDP
CCCCCCHHHHHHHHHCCHHHHHEEECCCCCEEECCCCCCEEEEEEEEEECCCCCCCCCCH
FRLGHKALAVNLSDLAACGATPLAFTLALALPRADDAWLEPFSRGLLRLADAHGCELVGG
HHHCCCCEEEEHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEECC
DTTQGPLNICITVFGEVPVVGGKGQALLRSGARAGDDLYVSGTLGDARLALEALRGALPL
CCCCCCCEEEEEEECCCCEECCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCC
PAEALAQARTRLEQPTPRVALGQALRGIASAAIDVSDGLLGDLRHILAASRVGATIQTEL
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
ATSLIASGSRSAGESAHISADKQLELILSGGDDYELAFTAPASARDAVEAASQQAQTPVT
HHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCHH
RIGSIETDPGLRLLNAQGQLMPGRFASFDHFA
HHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLGPMGEFDLIARYFTRPARRAVLGVGDDCALLQPAPGTQLAISCDMLVEGRHFFPDVDP
CCCCCCHHHHHHHHHCCHHHHHEEECCCCCEEECCCCCCEEEEEEEEEECCCCCCCCCCH
FRLGHKALAVNLSDLAACGATPLAFTLALALPRADDAWLEPFSRGLLRLADAHGCELVGG
HHHCCCCEEEEHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEECC
DTTQGPLNICITVFGEVPVVGGKGQALLRSGARAGDDLYVSGTLGDARLALEALRGALPL
CCCCCCCEEEEEEECCCCEECCCCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCC
PAEALAQARTRLEQPTPRVALGQALRGIASAAIDVSDGLLGDLRHILAASRVGATIQTEL
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
ATSLIASGSRSAGESAHISADKQLELILSGGDDYELAFTAPASARDAVEAASQQAQTPVT
HHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCHH
RIGSIETDPGLRLLNAQGQLMPGRFASFDHFA
HHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]