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The map label for this gene is dgoD1 [H]

Identifier: 91790245

GI number: 91790245

Start: 4658443

End: 4659570

Strand: Reverse

Name: dgoD1 [H]

Synonym: Bpro_4412

Alternate gene names: 91790245

Gene position: 4659570-4658443 (Counterclockwise)

Preceding gene: 91790246

Following gene: 91790244

Centisome position: 89.6

GC content: 58.69

Gene sequence:

>1128_bases
ATGAAGATCGCAGATATCCGTTGGTATGTGGTTCCCACGCCCTTCAAGGACTTCACGATGGTCGTTGTCGAAACAGACGA
CGGCATCACCGGTGTCGGCGAGGCCACCCTCGATTACCGATCCGGCCAGGTGTGCGCAGGCATCGACGCTGCTGCCCAAT
ACCTCAAAGGCCGCAGTGCCATTGGTGTCGAGCGAATTTGGGCAGATCTTCACGACCGGATCTTCTGGCGCGGGGGGCCA
GCCGATCTGGCCGCCCTCAGCGCTATAGATCAGGCACTGTGGGACATTGCCGGAAAATCAGCCGGTCTACCAGTTCATCA
GCTTTTAGGTGGGCCTTACCGGATGCGCGTGCGTGCATATCTGAATCAATGGTGGCGCGACATCGCTAAGGGCGCGGACC
TTGTCGACCTCGCTCGGATTGCTGTCTCAGAAGGGGCAACGGCATTGAAGTGGTATCCCTTCCGCTTCCTTCCGCAGCAT
GAGCAGAACTGGGCCGTGAGGCCTATTGAAGTTCAACGAGCCGTCGACGAGGTTGCGGCTGTGCGTGCGGTAGTTGGCCC
CAACATCGATCTGATGGTGGACTTATGGCGACGGCTTGACCGAGCGGCCGCGGCGCAGTTTTGTATGCAGGTGGCTCCAT
ATAACCTGCTTTTTGTCGAAGAACCGGTGATGGCTGAGAACCTCGAGGTGCTCTCTGGCTTGGCGCGGCAGTCTCCCGTT
CGTCTTGCGACAGGTGAGCGGCTCGCGGGAAGACAGGAGTTTCGCGCGGTGATTGAACGCCAGGCAGTGGGAATTGTGCA
GCCTTCCGTTATTCGTGTTGGTGGCATCACCGAGATGCGAAAAATTGCCGTGTTGGCTGAGATTTATGGAATAGGTGTTG
CGCCCCATAACCCGGTAGGCCCCATCGCCACAGCTGCGAGCGTGCAGGTGTGCGCGGCTATTCCCAACGCGGTGATGCTC
GAAACCTATGCCAACGGCGTGCCGGCTGTTAGAGATGAATTCATGTCGGTCAACTTGCTGCTGGATGGTGACGGCTTTAA
TGTCGGCACGCGGCCTGGTTTGGGCGTTGAGGTAGATGAAAAGGCCCTGAAGCGATTGGCAACTACCAGCGGGTCCGCCC
GGCCCTGA

Upstream 100 bases:

>100_bases
CGCCGCTTCCACGCGTGCCACTGCCCAGTGCGAGCTGGGTGCACCGGACGTACTGGTAGAGATCATCGTAACGGCCGCAG
CAGGAAAAGGTTCTGCATAA

Downstream 100 bases:

>100_bases
AATCCAAGGGCCAGCCGTGTGGTGTAGCGACCTGCGGTTTCCCGGCTCCTCTTGATATTCATCCAATTAGGCGATTAAAT
TGCCTGTTGCACGTTACAAG

Product: galactonate dehydratase

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKIADIRWYVVPTPFKDFTMVVVETDDGITGVGEATLDYRSGQVCAGIDAAAQYLKGRSAIGVERIWADLHDRIFWRGGP
ADLAALSAIDQALWDIAGKSAGLPVHQLLGGPYRMRVRAYLNQWWRDIAKGADLVDLARIAVSEGATALKWYPFRFLPQH
EQNWAVRPIEVQRAVDEVAAVRAVVGPNIDLMVDLWRRLDRAAAAQFCMQVAPYNLLFVEEPVMAENLEVLSGLARQSPV
RLATGERLAGRQEFRAVIERQAVGIVQPSVIRVGGITEMRKIAVLAEIYGIGVAPHNPVGPIATAASVQVCAAIPNAVML
ETYANGVPAVRDEFMSVNLLLDGDGFNVGTRPGLGVEVDEKALKRLATTSGSARP

Sequences:

>Translated_375_residues
MKIADIRWYVVPTPFKDFTMVVVETDDGITGVGEATLDYRSGQVCAGIDAAAQYLKGRSAIGVERIWADLHDRIFWRGGP
ADLAALSAIDQALWDIAGKSAGLPVHQLLGGPYRMRVRAYLNQWWRDIAKGADLVDLARIAVSEGATALKWYPFRFLPQH
EQNWAVRPIEVQRAVDEVAAVRAVVGPNIDLMVDLWRRLDRAAAAQFCMQVAPYNLLFVEEPVMAENLEVLSGLARQSPV
RLATGERLAGRQEFRAVIERQAVGIVQPSVIRVGGITEMRKIAVLAEIYGIGVAPHNPVGPIATAASVQVCAAIPNAVML
ETYANGVPAVRDEFMSVNLLLDGDGFNVGTRPGLGVEVDEKALKRLATTSGSARP
>Mature_375_residues
MKIADIRWYVVPTPFKDFTMVVVETDDGITGVGEATLDYRSGQVCAGIDAAAQYLKGRSAIGVERIWADLHDRIFWRGGP
ADLAALSAIDQALWDIAGKSAGLPVHQLLGGPYRMRVRAYLNQWWRDIAKGADLVDLARIAVSEGATALKWYPFRFLPQH
EQNWAVRPIEVQRAVDEVAAVRAVVGPNIDLMVDLWRRLDRAAAAQFCMQVAPYNLLFVEEPVMAENLEVLSGLARQSPV
RLATGERLAGRQEFRAVIERQAVGIVQPSVIRVGGITEMRKIAVLAEIYGIGVAPHNPVGPIATAASVQVCAAIPNAVML
ETYANGVPAVRDEFMSVNLLLDGDGFNVGTRPGLGVEVDEKALKRLATTSGSARP

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=379, Percent_Identity=34.0369393139842, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787864, Length=384, Percent_Identity=30.7291666666667, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI226510960, Length=362, Percent_Identity=27.6243093922652, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 40787; Mature: 40787

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00908 MR_MLE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIADIRWYVVPTPFKDFTMVVVETDDGITGVGEATLDYRSGQVCAGIDAAAQYLKGRSA
CCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCCCEEECHHHHHHHHCCCCC
IGVERIWADLHDRIFWRGGPADLAALSAIDQALWDIAGKSAGLPVHQLLGGPYRMRVRAY
CCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHH
LNQWWRDIAKGADLVDLARIAVSEGATALKWYPFRFLPQHEQNWAVRPIEVQRAVDEVAA
HHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHH
VRAVVGPNIDLMVDLWRRLDRAAAAQFCMQVAPYNLLFVEEPVMAENLEVLSGLARQSPV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCE
RLATGERLAGRQEFRAVIERQAVGIVQPSVIRVGGITEMRKIAVLAEIYGIGVAPHNPVG
EEECCCHHCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
PIATAASVQVCAAIPNAVMLETYANGVPAVRDEFMSVNLLLDGDGFNVGTRPGLGVEVDE
CHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHCCEEEEEEEECCCCCCCCCCCCCCEECH
KALKRLATTSGSARP
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIADIRWYVVPTPFKDFTMVVVETDDGITGVGEATLDYRSGQVCAGIDAAAQYLKGRSA
CCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCEEECCCCCEEECHHHHHHHHCCCCC
IGVERIWADLHDRIFWRGGPADLAALSAIDQALWDIAGKSAGLPVHQLLGGPYRMRVRAY
CCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHH
LNQWWRDIAKGADLVDLARIAVSEGATALKWYPFRFLPQHEQNWAVRPIEVQRAVDEVAA
HHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHH
VRAVVGPNIDLMVDLWRRLDRAAAAQFCMQVAPYNLLFVEEPVMAENLEVLSGLARQSPV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCE
RLATGERLAGRQEFRAVIERQAVGIVQPSVIRVGGITEMRKIAVLAEIYGIGVAPHNPVG
EEECCCHHCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
PIATAASVQVCAAIPNAVMLETYANGVPAVRDEFMSVNLLLDGDGFNVGTRPGLGVEVDE
CHHHHHHHHHHHHCCCCEEEHHHHCCCCHHHHCCEEEEEEEECCCCCCCCCCCCCCEECH
KALKRLATTSGSARP
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA