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The map label for this gene is btr [H]

Identifier: 91790132

GI number: 91790132

Start: 4529543

End: 4530361

Strand: Reverse

Name: btr [H]

Synonym: Bpro_4294

Alternate gene names: 91790132

Gene position: 4530361-4529543 (Counterclockwise)

Preceding gene: 91790133

Following gene: 91790131

Centisome position: 87.12

GC content: 63.25

Gene sequence:

>819_bases
ATGAAACCAACCGACCCGCAGGAGAAATGCATGTCAGGCCTGACCCTTGAAACTCCCGTTTCCCCGATCCGCTTTGTATC
CCGGCAGCCTTCCGCCCGGTCCGGGGCTGTCGCACCGCTGAAAGTTCTTTGCTCCAGTTGCCATCTGCGTGACTTGTGCC
TGCCCTGCGGAATGACGGGCATCGATGTGGCCCGCCTGGACAGTTTGATGTTCGGCCGGCGCAAGGTCAGGACTGGGGAG
GCCCTCTACCGCGAGGGTGACCGTTTCCAGTTCATTTACGCTGTGCGCAGCGGCACGTTCAAGTCCAGCCTCACGCTGGC
GGATGGCCGCGAGCAGGTCAGCGCCTTCCACATGGCGGGTGAACTGATGGGTCTGGATGGGGTGGCCCACGGCACACACG
CGAGCAGCGCCACGGCGCTGGAGGACACCGAAATCTGCGCCATTCCCTATGCGCATCTCACCGAGCTGGCGGCGGGCAAT
GCGGGCACGCAGAATCTGGTCAGCCGGCTGATGAGCCGTGAAATCGTGCGCGAGCACAGCCTCATGATGCTGCTGGGCAG
CATGAATGCCGAGGAGCGCCTGGCGGCCTTCCTGCTGAACCTGTCGCAGCGGCTGAGGGCCCGCGGCTACGCGGCCAACG
AGTTCCACCTGAGGATGTCCCGGGCCGAAATCGGCAGCTACCTGGGCATGAAGCTGGAGACCGTGAGCCGGACCTTTTCG
GCTTTTCAGCAGAAACGCCTGCTGGAGGTCGACAAGCGCCACATCCGCATTACCGATCCGGACGGTCTGACGCGGTCGTT
CGAGATGCATGTGCATTGA

Upstream 100 bases:

>100_bases
AGCGCTATCTCGACGAGGGCGCCTACCGTTTCCTCGACAAGAGCACCGAATTCGACCAGCTCGCGCAGACCGTGGCGTCC
GCGTCTGAGAGGGCTGTGCA

Downstream 100 bases:

>100_bases
GTGCTTCGCAGGTCATTGAAGCGCGGGCGGTTGATGTGAATCAAAGCGCCGCCGGGGCAGGCCCGCTAAGCTGACACGCT
TTGACCCACGACCCTGCCGC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKPTDPQEKCMSGLTLETPVSPIRFVSRQPSARSGAVAPLKVLCSSCHLRDLCLPCGMTGIDVARLDSLMFGRRKVRTGE
ALYREGDRFQFIYAVRSGTFKSSLTLADGREQVSAFHMAGELMGLDGVAHGTHASSATALEDTEICAIPYAHLTELAAGN
AGTQNLVSRLMSREIVREHSLMMLLGSMNAEERLAAFLLNLSQRLRARGYAANEFHLRMSRAEIGSYLGMKLETVSRTFS
AFQQKRLLEVDKRHIRITDPDGLTRSFEMHVH

Sequences:

>Translated_272_residues
MKPTDPQEKCMSGLTLETPVSPIRFVSRQPSARSGAVAPLKVLCSSCHLRDLCLPCGMTGIDVARLDSLMFGRRKVRTGE
ALYREGDRFQFIYAVRSGTFKSSLTLADGREQVSAFHMAGELMGLDGVAHGTHASSATALEDTEICAIPYAHLTELAAGN
AGTQNLVSRLMSREIVREHSLMMLLGSMNAEERLAAFLLNLSQRLRARGYAANEFHLRMSRAEIGSYLGMKLETVSRTFS
AFQQKRLLEVDKRHIRITDPDGLTRSFEMHVH
>Mature_272_residues
MKPTDPQEKCMSGLTLETPVSPIRFVSRQPSARSGAVAPLKVLCSSCHLRDLCLPCGMTGIDVARLDSLMFGRRKVRTGE
ALYREGDRFQFIYAVRSGTFKSSLTLADGREQVSAFHMAGELMGLDGVAHGTHASSATALEDTEICAIPYAHLTELAAGN
AGTQNLVSRLMSREIVREHSLMMLLGSMNAEERLAAFLLNLSQRLRARGYAANEFHLRMSRAEIGSYLGMKLETVSRTFS
AFQQKRLLEVDKRHIRITDPDGLTRSFEMHVH

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=233, Percent_Identity=38.1974248927039, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 30132; Mature: 30132

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTDPQEKCMSGLTLETPVSPIRFVSRQPSARSGAVAPLKVLCSSCHLRDLCLPCGMTG
CCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCC
IDVARLDSLMFGRRKVRTGEALYREGDRFQFIYAVRSGTFKSSLTLADGREQVSAFHMAG
CHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCCCEEECCCHHHHHHHHHHH
ELMGLDGVAHGTHASSATALEDTEICAIPYAHLTELAAGNAGTQNLVSRLMSREIVREHS
HHHCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LMMLLGSMNAEERLAAFLLNLSQRLRARGYAANEFHLRMSRAEIGSYLGMKLETVSRTFS
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEHHHHHHHHHCCHHHHHHHHHH
AFQQKRLLEVDKRHIRITDPDGLTRSFEMHVH
HHHHHHHHHHCCCEEEEECCCCCCCCEEEECC
>Mature Secondary Structure
MKPTDPQEKCMSGLTLETPVSPIRFVSRQPSARSGAVAPLKVLCSSCHLRDLCLPCGMTG
CCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCC
IDVARLDSLMFGRRKVRTGEALYREGDRFQFIYAVRSGTFKSSLTLADGREQVSAFHMAG
CHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCCCEEECCCHHHHHHHHHHH
ELMGLDGVAHGTHASSATALEDTEICAIPYAHLTELAAGNAGTQNLVSRLMSREIVREHS
HHHCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LMMLLGSMNAEERLAAFLLNLSQRLRARGYAANEFHLRMSRAEIGSYLGMKLETVSRTFS
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEHHHHHHHHHCCHHHHHHHHHH
AFQQKRLLEVDKRHIRITDPDGLTRSFEMHVH
HHHHHHHHHHCCCEEEEECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]