Click here to switch to the map view.

The map label for this gene is kdpE [H]

Identifier: 91790091

GI number: 91790091

Start: 4480419

End: 4481105

Strand: Reverse

Name: kdpE [H]

Synonym: Bpro_4253

Alternate gene names: 91790091

Gene position: 4481105-4480419 (Counterclockwise)

Preceding gene: 91790092

Following gene: 91790090

Centisome position: 86.17

GC content: 67.69

Gene sequence:

>687_bases
ATGACCCTGCGGGTGCTGGTCGTGGAAGACGACCGGGAAATACGGGCGTTGATGCAGTCATCCCTCGCCGTGGAGGGGTT
TGACGTCCGGACCGCGGCCTCGCTGAGCGAGGCTGGCGCGCTGTTGCGCCACGACCCGCCCGATGTCATCGTTCTCGATT
TGGGGCTGCCCGACGGGGATGGCGTGCAACTGGTGCGCGAGGTGCGCCGGCAGCAGTCGGTGCCCATCATCGTGGTGTCG
GCCCGCCATCAGGAGGCGCAGAAAATCGCGCTGCTCGATGCGGGGGCGGATGACTACCTGACCAAGCCCTTCAGCGTGGG
CGAGCTGCTGGCACGCATCCGGGTTGCCCTGCGGCATCGCGGCACGGCGCTGGCCGCGGCCGTGACGGTGCATGAGCTGG
ACGATTTGCGCATTGACCTGGCGGCGCATGTGGTGCTGCGCGCCGGTGAAACCCTGCATCTCACGCCTACCGAATTCAAG
CTGCTGGCGCGCCTGGTGCGAAGCGCCGGCCGGGTGGTGACGCACCGGCAGCTGCTGGTCGACGTGTGGGGTCCTGAATT
CACCGAGCACACGCACTACCTGCGGCTCTACATGGCCCAACTGCGCGCAAAAATCGAGCAGGATCCGGCCGAGCCGCGGC
ATCTGCTGACCGAGACGGGGGTCGGTTACCGGCTGGCGGACGCCTGA

Upstream 100 bases:

>100_bases
CCCATGGCGGGCGGCTCGCGCTCAGGCGCCGCAGTGGGGGTGGCAGCTGCTTCACTGTCAGCCTGCCGATCGAGGCCCAG
CCCATAGGGAAGGACCTGCC

Downstream 100 bases:

>100_bases
GGGGGGCGCCGGCCCGGCGCCATCCTTATGCGTTCCTGATGCGGGTGCGGCGACAGTGCAGCCCTGTTCTTCATCGATCG
CTTTCAATGAATCAAATTTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTLRVLVVEDDREIRALMQSSLAVEGFDVRTAASLSEAGALLRHDPPDVIVLDLGLPDGDGVQLVREVRRQQSVPIIVVS
ARHQEAQKIALLDAGADDYLTKPFSVGELLARIRVALRHRGTALAAAVTVHELDDLRIDLAAHVVLRAGETLHLTPTEFK
LLARLVRSAGRVVTHRQLLVDVWGPEFTEHTHYLRLYMAQLRAKIEQDPAEPRHLLTETGVGYRLADA

Sequences:

>Translated_228_residues
MTLRVLVVEDDREIRALMQSSLAVEGFDVRTAASLSEAGALLRHDPPDVIVLDLGLPDGDGVQLVREVRRQQSVPIIVVS
ARHQEAQKIALLDAGADDYLTKPFSVGELLARIRVALRHRGTALAAAVTVHELDDLRIDLAAHVVLRAGETLHLTPTEFK
LLARLVRSAGRVVTHRQLLVDVWGPEFTEHTHYLRLYMAQLRAKIEQDPAEPRHLLTETGVGYRLADA
>Mature_227_residues
TLRVLVVEDDREIRALMQSSLAVEGFDVRTAASLSEAGALLRHDPPDVIVLDLGLPDGDGVQLVREVRRQQSVPIIVVSA
RHQEAQKIALLDAGADDYLTKPFSVGELLARIRVALRHRGTALAAAVTVHELDDLRIDLAAHVVLRAGETLHLTPTEFKL
LARLVRSAGRVVTHRQLLVDVWGPEFTEHTHYLRLYMAQLRAKIEQDPAEPRHLLTETGVGYRLADA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=53.6036036036036, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.2422907488987, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=34.9344978165939, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=35.8744394618834, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=31.390134529148, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=34.8214285714286, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=33.7719298245614, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=33.7777777777778, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.004329004329, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=33.6244541484716, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=33.0396475770925, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=32.1739130434783, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=30.0429184549356, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=26.7241379310345, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=28.3582089552239, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=31.8965517241379, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25252; Mature: 25121

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRVLVVEDDREIRALMQSSLAVEGFDVRTAASLSEAGALLRHDPPDVIVLDLGLPDGD
CEEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHCCCCCCEEEEECCCCCCC
GVQLVREVRRQQSVPIIVVSARHQEAQKIALLDAGADDYLTKPFSVGELLARIRVALRHR
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHC
GTALAAAVTVHELDDLRIDLAAHVVLRAGETLHLTPTEFKLLARLVRSAGRVVTHRQLLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHEE
DVWGPEFTEHTHYLRLYMAQLRAKIEQDPAEPRHLLTETGVGYRLADA
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
TLRVLVVEDDREIRALMQSSLAVEGFDVRTAASLSEAGALLRHDPPDVIVLDLGLPDGD
EEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHCCCCCCEEEEECCCCCCC
GVQLVREVRRQQSVPIIVVSARHQEAQKIALLDAGADDYLTKPFSVGELLARIRVALRHR
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHC
GTALAAAVTVHELDDLRIDLAAHVVLRAGETLHLTPTEFKLLARLVRSAGRVVTHRQLLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHEE
DVWGPEFTEHTHYLRLYMAQLRAKIEQDPAEPRHLLTETGVGYRLADA
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]