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The map label for this gene is kdpD [H]

Identifier: 91790092

GI number: 91790092

Start: 4481102

End: 4482646

Strand: Reverse

Name: kdpD [H]

Synonym: Bpro_4254

Alternate gene names: 91790092

Gene position: 4482646-4481102 (Counterclockwise)

Preceding gene: 91790093

Following gene: 91790091

Centisome position: 86.2

GC content: 68.54

Gene sequence:

>1545_bases
ATGATGAATGCTCCAACAGTCCAGGACGGCGATGTTGCATCGGCCCGGGGCTGGGTCACGGTTGCGTTGCTGCTGGTGGC
GGCCACGCTTGTCAGCATGTTGCTCGACCAGCATGTGGCGCTCATGAGCCAAGCCATGATTTATGTGCTGGCCGTCGTCA
TCGCCTCGTACAGGCTGCGCAGGATCGAATCGGTGGTTTGCGCGGTCGGTGCTGTGACCACCTTGAACTTCTTTTTTGTG
CCCCCGCGCTGGACCCTGGTTGTCGAGAATCGCGAGCTCTTCATCGGGCTGGCGACCATGCTGGTGCTTGCGCTGGTCAT
CAGCCATCTGGCGACGCGTCTTCGGCGCGAGTCGGAGACGGCCCGCCTGAGTGAACGGCGAGCGCGCCAGTTGCAGGGCT
TGTCCACCGACCTGGCCAGCGCGGCATCGCCGGCGGAGGTCCTGTCGCTGGGGCAGCGGGCGCTGGACACGGCCTTTGCC
GGGCCGTGCACCCTGGTGCTGGCCAATGACCGGCACGAGCTACCCGACGCGGCGGCGGAGCCGGCCGTGCTGGATGGCCT
GCGCTGCTGCATGAACGAGGCGGCCGTGCTCGGGCCGGGGACGGGACGCTGGCCGGGGCTCAATGCCTGGTACCTCCCGC
TGGGTGACAAGGCGCGCACGGTTGTCGGCGCGGCCTGCGTCCGTCCCGCGCTGTCGGGCGACACGGACGGCCGGGAGCAC
GCGCAGGCGCTGTGTGCCCTGCTGGCGCAGTCACTGTGGCGGCTGCGCCTCAGCGCGTCGGTCGCCGAGGCGCAGGGCGA
GATGCAACGCCACCAGTTGCAAAGCACCTTTCTCGCCGCGGTGTCGCACGACCTGCGCACGCCGCTGGCCGCGATCATGG
GCGCGGCATCGTCCCTGCAAACCCAGCGCGACCGGCTGCCGTTGCCGGATCAGGACCGGCTGCTCGACAGCATTGTCAAC
GAGGCGTCTTACCTGAGCGAGGTGACGGAGAACACCCTGCAATTCGTGCGGCTGTCCAGCTCGGAGCAGGCGCTTCGCCG
CGACTGGGAGTCCATCGAGGAGATTGTCGGCGCCGTGCTGGCGCGCGTGCGCCAGCGTGACCCGCAGCGCCGCATCAAGT
CCAGGGTGGCGAGTGGCTTGCCGCTGATCAGGGCGGACCCGGTGCTGCTCGCCCAGATGCTGGGCAACCTGCTCGACAAT
GCGCTGAAATACAGCGATGGCACCGTCGACCTGACAGTGGGTGTGACAGGCGTGGTCGCAGCGGTGGGGACGGCGGGGGT
GAGTGCCGACAACCTGGAACTGGAGATCGCGGTGAAAGACCGCGGACCCGGTGTTCCCGAGGCAGACCAGGAGGCGATTT
TTGAGCCCTATGCGCGCGGTGAGCAGTCCGGCCACCGGGGTGCCGGGCTGGGTCTGGCGGTGTGCCGCGCCATTGCCGCG
GCCCATGGCGGGCGGCTCGCGCTCAGGCGCCGCAGTGGGGGTGGCAGCTGCTTCACTGTCAGCCTGCCGATCGAGGCCCA
GCCCATAGGGAAGGACCTGCCATGA

Upstream 100 bases:

>100_bases
CAGCAAGACCGCGTTCTGACGCCCGCCTCGAACCGGGGCGGGCTTGTCCGCCTCTGCGTTCCTTATACATTCCTGATGGG
CCCGGTGTTACGCTGATCGC

Downstream 100 bases:

>100_bases
CCCTGCGGGTGCTGGTCGTGGAAGACGACCGGGAAATACGGGCGTTGATGCAGTCATCCCTCGCCGTGGAGGGGTTTGAC
GTCCGGACCGCGGCCTCGCT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MMNAPTVQDGDVASARGWVTVALLLVAATLVSMLLDQHVALMSQAMIYVLAVVIASYRLRRIESVVCAVGAVTTLNFFFV
PPRWTLVVENRELFIGLATMLVLALVISHLATRLRRESETARLSERRARQLQGLSTDLASAASPAEVLSLGQRALDTAFA
GPCTLVLANDRHELPDAAAEPAVLDGLRCCMNEAAVLGPGTGRWPGLNAWYLPLGDKARTVVGAACVRPALSGDTDGREH
AQALCALLAQSLWRLRLSASVAEAQGEMQRHQLQSTFLAAVSHDLRTPLAAIMGAASSLQTQRDRLPLPDQDRLLDSIVN
EASYLSEVTENTLQFVRLSSSEQALRRDWESIEEIVGAVLARVRQRDPQRRIKSRVASGLPLIRADPVLLAQMLGNLLDN
ALKYSDGTVDLTVGVTGVVAAVGTAGVSADNLELEIAVKDRGPGVPEADQEAIFEPYARGEQSGHRGAGLGLAVCRAIAA
AHGGRLALRRRSGGGSCFTVSLPIEAQPIGKDLP

Sequences:

>Translated_514_residues
MMNAPTVQDGDVASARGWVTVALLLVAATLVSMLLDQHVALMSQAMIYVLAVVIASYRLRRIESVVCAVGAVTTLNFFFV
PPRWTLVVENRELFIGLATMLVLALVISHLATRLRRESETARLSERRARQLQGLSTDLASAASPAEVLSLGQRALDTAFA
GPCTLVLANDRHELPDAAAEPAVLDGLRCCMNEAAVLGPGTGRWPGLNAWYLPLGDKARTVVGAACVRPALSGDTDGREH
AQALCALLAQSLWRLRLSASVAEAQGEMQRHQLQSTFLAAVSHDLRTPLAAIMGAASSLQTQRDRLPLPDQDRLLDSIVN
EASYLSEVTENTLQFVRLSSSEQALRRDWESIEEIVGAVLARVRQRDPQRRIKSRVASGLPLIRADPVLLAQMLGNLLDN
ALKYSDGTVDLTVGVTGVVAAVGTAGVSADNLELEIAVKDRGPGVPEADQEAIFEPYARGEQSGHRGAGLGLAVCRAIAA
AHGGRLALRRRSGGGSCFTVSLPIEAQPIGKDLP
>Mature_514_residues
MMNAPTVQDGDVASARGWVTVALLLVAATLVSMLLDQHVALMSQAMIYVLAVVIASYRLRRIESVVCAVGAVTTLNFFFV
PPRWTLVVENRELFIGLATMLVLALVISHLATRLRRESETARLSERRARQLQGLSTDLASAASPAEVLSLGQRALDTAFA
GPCTLVLANDRHELPDAAAEPAVLDGLRCCMNEAAVLGPGTGRWPGLNAWYLPLGDKARTVVGAACVRPALSGDTDGREH
AQALCALLAQSLWRLRLSASVAEAQGEMQRHQLQSTFLAAVSHDLRTPLAAIMGAASSLQTQRDRLPLPDQDRLLDSIVN
EASYLSEVTENTLQFVRLSSSEQALRRDWESIEEIVGAVLARVRQRDPQRRIKSRVASGLPLIRADPVLLAQMLGNLLDN
ALKYSDGTVDLTVGVTGVVAAVGTAGVSADNLELEIAVKDRGPGVPEADQEAIFEPYARGEQSGHRGAGLGLAVCRAIAA
AHGGRLALRRRSGGGSCFTVSLPIEAQPIGKDLP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=526, Percent_Identity=31.1787072243346, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=32.0143884892086, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=26.9076305220884, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=26.8292682926829, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=272, Percent_Identity=30.8823529411765, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=29.5546558704453, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=238, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=31.404958677686, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=28.2945736434109, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=26.7206477732794, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788279, Length=230, Percent_Identity=26.9565217391304, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789808, Length=232, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=27.9835390946502, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=25.8474576271186, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=282, Percent_Identity=25.886524822695, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=25.4237288135593, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54864; Mature: 54864

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNAPTVQDGDVASARGWVTVALLLVAATLVSMLLDQHVALMSQAMIYVLAVVIASYRLR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIESVVCAVGAVTTLNFFFVPPRWTLVVENRELFIGLATMLVLALVISHLATRLRRESET
HHHHHHHHHHHHHHHEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLSERRARQLQGLSTDLASAASPAEVLSLGQRALDTAFAGPCTLVLANDRHELPDAAAE
HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
PAVLDGLRCCMNEAAVLGPGTGRWPGLNAWYLPLGDKARTVVGAACVRPALSGDTDGREH
CHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHH
AQALCALLAQSLWRLRLSASVAEAQGEMQRHQLQSTFLAAVSHDLRTPLAAIMGAASSLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQRDRLPLPDQDRLLDSIVNEASYLSEVTENTLQFVRLSSSEQALRRDWESIEEIVGAVL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARVRQRDPQRRIKSRVASGLPLIRADPVLLAQMLGNLLDNALKYSDGTVDLTVGVTGVVA
HHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHH
AVGTAGVSADNLELEIAVKDRGPGVPEADQEAIFEPYARGEQSGHRGAGLGLAVCRAIAA
HHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AHGGRLALRRRSGGGSCFTVSLPIEAQPIGKDLP
HCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MMNAPTVQDGDVASARGWVTVALLLVAATLVSMLLDQHVALMSQAMIYVLAVVIASYRLR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIESVVCAVGAVTTLNFFFVPPRWTLVVENRELFIGLATMLVLALVISHLATRLRRESET
HHHHHHHHHHHHHHHEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLSERRARQLQGLSTDLASAASPAEVLSLGQRALDTAFAGPCTLVLANDRHELPDAAAE
HHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
PAVLDGLRCCMNEAAVLGPGTGRWPGLNAWYLPLGDKARTVVGAACVRPALSGDTDGREH
CHHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHH
AQALCALLAQSLWRLRLSASVAEAQGEMQRHQLQSTFLAAVSHDLRTPLAAIMGAASSLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQRDRLPLPDQDRLLDSIVNEASYLSEVTENTLQFVRLSSSEQALRRDWESIEEIVGAVL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ARVRQRDPQRRIKSRVASGLPLIRADPVLLAQMLGNLLDNALKYSDGTVDLTVGVTGVVA
HHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHH
AVGTAGVSADNLELEIAVKDRGPGVPEADQEAIFEPYARGEQSGHRGAGLGLAVCRAIAA
HHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AHGGRLALRRRSGGGSCFTVSLPIEAQPIGKDLP
HCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]