| Definition | Polaromonas sp. JS666 chromosome, complete genome. |
|---|---|
| Accession | NC_007948 |
| Length | 5,200,264 |
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The map label for this gene is ykvO [H]
Identifier: 91790043
GI number: 91790043
Start: 4423830
End: 4424579
Strand: Direct
Name: ykvO [H]
Synonym: Bpro_4205
Alternate gene names: 91790043
Gene position: 4423830-4424579 (Clockwise)
Preceding gene: 91790032
Following gene: 91790045
Centisome position: 85.07
GC content: 65.33
Gene sequence:
>750_bases ATGCAGAACTTTGACAACAAAACCGTACTCGTCACCGGCGGCAGCAGCGGCATCGGCCTGGCCACCGCGCTCCAATTTGC CAAACAGGGCGCACGCGTCATCATCACGGGCCGCGACCAGGCCGCGCTGGACCGGACTCGTGCCGAGCTCGGCGCCAACG CAGTGGCCCTGCGCCATGACGCCGGTGATATCCACGCCGCCAAAGCCCTGGCGGCCAGCCTGAAAGAGCAGGGCATCACA CTGGACGCGCTGTTCGTCAACGCCGGCGTGGCGAAATTCGCGCCCCTCGAGGCCGTTGAAGAAGACATCTGGGACCAGAC CTTCAACACCAACGTCAAGGGCGCCTTCTTCACCATCCAGGCGCTGTCGCCGCTGCTCAACACGGGCGCGGCCATCATCC TGAATGGCTCCATCAACGCCCACATCGGCATGCCGAACTCCAGCGTGTACGCCGCCAGCAAGGCTGCGCTGATTTCGCTG GCCAAAACGTTGTCGGGTGAACTGATCAGCCGCGGCATCCGTGTCAACGTGGTGAGCCCCGGCCCGGTGCAAACGCCGCT CTATGGCAAGCTGGGTGTGCCCGCCGACCAGCTCGATGCGCTGGCCGCCGGCATTCAGGCGCAGGTTCCGCTGAAACGCT TCGGCACGCCCGATGAAGTGGCCAGCGCCGTCGTGTACCTGTCGTCGCCGGCGGCAGCCTTCATTGTCGGCACCGAGCTG ATCGTGGACGGCGGCATGAGCCAGCTCTGA
Upstream 100 bases:
>100_bases ATCAAAGGTAAATCCTACAGTTCATCCATCGGCGGGCACATCGCACACCGACTTCCTCCACACCTTCTCCAGACCTCCTC ACACAACCCAAGGAATCATC
Downstream 100 bases:
>100_bases GCAAGGTGAACCACAAAAAAAAAGGCGGTGCCGCAAGGCCCGCCTTTTTTTACAACGGCGCGTGCCGCGTAACGAGTCAG TACTGCCAGAAAATCCGCTG
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MQNFDNKTVLVTGGSSGIGLATALQFAKQGARVIITGRDQAALDRTRAELGANAVALRHDAGDIHAAKALAASLKEQGIT LDALFVNAGVAKFAPLEAVEEDIWDQTFNTNVKGAFFTIQALSPLLNTGAAIILNGSINAHIGMPNSSVYAASKAALISL AKTLSGELISRGIRVNVVSPGPVQTPLYGKLGVPADQLDALAAGIQAQVPLKRFGTPDEVASAVVYLSSPAAAFIVGTEL IVDGGMSQL
Sequences:
>Translated_249_residues MQNFDNKTVLVTGGSSGIGLATALQFAKQGARVIITGRDQAALDRTRAELGANAVALRHDAGDIHAAKALAASLKEQGIT LDALFVNAGVAKFAPLEAVEEDIWDQTFNTNVKGAFFTIQALSPLLNTGAAIILNGSINAHIGMPNSSVYAASKAALISL AKTLSGELISRGIRVNVVSPGPVQTPLYGKLGVPADQLDALAAGIQAQVPLKRFGTPDEVASAVVYLSSPAAAFIVGTEL IVDGGMSQL >Mature_249_residues MQNFDNKTVLVTGGSSGIGLATALQFAKQGARVIITGRDQAALDRTRAELGANAVALRHDAGDIHAAKALAASLKEQGIT LDALFVNAGVAKFAPLEAVEEDIWDQTFNTNVKGAFFTIQALSPLLNTGAAIILNGSINAHIGMPNSSVYAASKAALISL AKTLSGELISRGIRVNVVSPGPVQTPLYGKLGVPADQLDALAAGIQAQVPLKRFGTPDEVASAVVYLSSPAAAFIVGTEL IVDGGMSQL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.1285140562249, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=32.2709163346614, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=32.0158102766798, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=33.8645418326693, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=30.2788844621514, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=32.2448979591837, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=28.4, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=35.6756756756757, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI223718074, Length=206, Percent_Identity=33.9805825242718, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=31.1475409836066, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=31.5555555555556, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=34.0540540540541, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=30.6772908366534, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=32.9842931937173, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI225579078, Length=207, Percent_Identity=30.9178743961353, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=28.8617886178862, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI142976729, Length=189, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI10190746, Length=264, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=29.5336787564767, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI7706523, Length=207, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=35.7723577235772, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=34.9397590361446, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=34.2741935483871, Blast_Score=114, Evalue=9e-27, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=35.8870967741936, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=29.1338582677165, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=30.4878048780488, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=31.9838056680162, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=28.6290322580645, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=32.7868852459016, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=29.957805907173, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=30.4, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=28.2258064516129, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI1787526, Length=213, Percent_Identity=29.1079812206573, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.4591439688716, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1787545, Length=254, Percent_Identity=25.9842519685039, Blast_Score=63, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=32.5396825396825, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=31.9230769230769, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=32.1969696969697, Blast_Score=113, Evalue=7e-26, Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=34.7014925373134, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=31.9702602230483, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=30.7692307692308, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.7086614173228, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=32.4427480916031, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=30.3703703703704, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=33.9920948616601, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.1740890688259, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=31.3432835820896, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.4182509505703, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.1666666666667, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=33.2075471698113, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.5589353612167, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=30.6451612903226, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=31.0606060606061, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=30.3149606299213, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=31.6981132075472, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=30.9433962264151, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.811320754717, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.0606060606061, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.1115241635688, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=28.6274509803922, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=30.1587301587302, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17561272, Length=240, Percent_Identity=28.75, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17567345, Length=189, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=30.2681992337165, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=32.9896907216495, Blast_Score=71, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=198, Percent_Identity=30.3030303030303, Blast_Score=66, Evalue=4e-12, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=33.4661354581673, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=36.0995850622407, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.4741035856574, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=31.8897637795276, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=32.3886639676113, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=31.1023622047244, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=32.1285140562249, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=30.241935483871, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=28.643216080402, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=30.3418803418803, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI45554248, Length=236, Percent_Identity=30.9322033898305, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640117, Length=236, Percent_Identity=30.9322033898305, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24581726, Length=198, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=30.9278350515464, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=25.0996015936255, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 25587; Mature: 25587
Theoretical pI: Translated: 6.26; Mature: 6.26
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 1.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQNFDNKTVLVTGGSSGIGLATALQFAKQGARVIITGRDQAALDRTRAELGANAVALRHD CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCEEEEECC AGDIHAAKALAASLKEQGITLDALFVNAGVAKFAPLEAVEEDIWDQTFNTNVKGAFFTIQ CCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCHHHHHHHHHHHHHCCCCCCEEEEEHH ALSPLLNTGAAIILNGSINAHIGMPNSSVYAASKAALISLAKTLSGELISRGIRVNVVSP HHHHHHHCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC GPVQTPLYGKLGVPADQLDALAAGIQAQVPLKRFGTPDEVASAVVYLSSPAAAFIVGTEL CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHEEEEECCCCEEEEEEHHH IVDGGMSQL EECCCCCCC >Mature Secondary Structure MQNFDNKTVLVTGGSSGIGLATALQFAKQGARVIITGRDQAALDRTRAELGANAVALRHD CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCEEEEECC AGDIHAAKALAASLKEQGITLDALFVNAGVAKFAPLEAVEEDIWDQTFNTNVKGAFFTIQ CCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHCHHHHHHHHHHHHHCCCCCCEEEEEHH ALSPLLNTGAAIILNGSINAHIGMPNSSVYAASKAALISLAKTLSGELISRGIRVNVVSP HHHHHHHCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC GPVQTPLYGKLGVPADQLDALAAGIQAQVPLKRFGTPDEVASAVVYLSSPAAAFIVGTEL CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHEEEEECCCCEEEEEEHHH IVDGGMSQL EECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]