Click here to switch to the map view.

The map label for this gene is lysR [H]

Identifier: 91790045

GI number: 91790045

Start: 4425912

End: 4426820

Strand: Direct

Name: lysR [H]

Synonym: Bpro_4207

Alternate gene names: 91790045

Gene position: 4425912-4426820 (Clockwise)

Preceding gene: 91790043

Following gene: 91790048

Centisome position: 85.11

GC content: 65.13

Gene sequence:

>909_bases
ATGAACCTCCGGCAACTTGAAGTCTTTCAGGCCGTCATGCAGGCCGGCAACATGAGCGCGGCCGCGCGCCTGATCTGCAT
CACGCCTTCGGCCGTCAGCAAGACCATTGCGCATACCGAGCTCCAGCTGGGCTACAAGCTGTTCACGCGCGGCAAGGGCA
CGCTGGCCCCCACGCCGGAAGCCCGGGTGCTGTTCGAAGAGTCGACAGTGATCCATTGCAAGCTCGATGAACTCAAGCGC
ATTGCGCTCAATTTGCGGCAGGCTGACGACGGCCAGGTGCGGCTGGCCGCCATCCCGTCCATCTGCCATGAGTTCTTGCC
GCTGGTGCTGGAAAAGCACCTGGCCCGCTATCCGCGCGTCAAGATTGAAGTGCGCACCCTGCACCAGGACCAGATGGTGC
AGGCCCTGCTCACGCGCAGCGTCGACTTCGCGCTGGGCTACTACGAGCACCCGCACCCGCTGCTGACCAGCCAGATGCTG
GTCAGGGGGCCACTCTATCTGGCGGTGACGCGGGATGTCTGGCTGCGCGCCGTACGCACCCGGCGCCTGAACCCGATGTC
GTTTCTGGCCAGCATGCCACTGATCCGGCTGGTGGGCGAAGACCCCATGTGCCAGTCGATTGACGAGCTGGCCGGCCACT
TGGGGCTGACGGCGCCGGCCGGCCTGCAGGTGCACACCTCCCGGCTGGCGCTGGAACTGGTCAAGCGCGGCATGGGCTGG
ACGGTGGTCGACTTCCTGACGGCCAGCAACCTGGATCCGTCATCCATCAGTGCCGTGGCACTGCATGACTTTGCACCGAT
TCCGCTGCAGATGTACTTTGCAACCAGCACGCCGCCGGGCCAGGACGCCTTGCGCCTGCTGGGCATGCTGCCAGACTTGC
TGCGCGGGGTGATGGCGTCCAGCCATTGA

Upstream 100 bases:

>100_bases
GCCTCAGGGCGAAAGGTGGCTCATCGTAGCCATGGCCAACAGGCGCAGCGATGCATAATCAAGCGCAGGGTGTGAACAAA
ACTCACACCCCTCCCAAGCC

Downstream 100 bases:

>100_bases
GCAGGCCGGATATCGCGTATCGCGAGAAGGGCTCAGCGGCGGCGCAGCACCAGCGCCAGCCCCGCAATCCCCAGGCCCAG
CGCCCACAGCGGCCACAGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MNLRQLEVFQAVMQAGNMSAAARLICITPSAVSKTIAHTELQLGYKLFTRGKGTLAPTPEARVLFEESTVIHCKLDELKR
IALNLRQADDGQVRLAAIPSICHEFLPLVLEKHLARYPRVKIEVRTLHQDQMVQALLTRSVDFALGYYEHPHPLLTSQML
VRGPLYLAVTRDVWLRAVRTRRLNPMSFLASMPLIRLVGEDPMCQSIDELAGHLGLTAPAGLQVHTSRLALELVKRGMGW
TVVDFLTASNLDPSSISAVALHDFAPIPLQMYFATSTPPGQDALRLLGMLPDLLRGVMASSH

Sequences:

>Translated_302_residues
MNLRQLEVFQAVMQAGNMSAAARLICITPSAVSKTIAHTELQLGYKLFTRGKGTLAPTPEARVLFEESTVIHCKLDELKR
IALNLRQADDGQVRLAAIPSICHEFLPLVLEKHLARYPRVKIEVRTLHQDQMVQALLTRSVDFALGYYEHPHPLLTSQML
VRGPLYLAVTRDVWLRAVRTRRLNPMSFLASMPLIRLVGEDPMCQSIDELAGHLGLTAPAGLQVHTSRLALELVKRGMGW
TVVDFLTASNLDPSSISAVALHDFAPIPLQMYFATSTPPGQDALRLLGMLPDLLRGVMASSH
>Mature_302_residues
MNLRQLEVFQAVMQAGNMSAAARLICITPSAVSKTIAHTELQLGYKLFTRGKGTLAPTPEARVLFEESTVIHCKLDELKR
IALNLRQADDGQVRLAAIPSICHEFLPLVLEKHLARYPRVKIEVRTLHQDQMVQALLTRSVDFALGYYEHPHPLLTSQML
VRGPLYLAVTRDVWLRAVRTRRLNPMSFLASMPLIRLVGEDPMCQSIDELAGHLGLTAPAGLQVHTSRLALELVKRGMGW
TVVDFLTASNLDPSSISAVALHDFAPIPLQMYFATSTPPGQDALRLLGMLPDLLRGVMASSH

Specific function: This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789204, Length=124, Percent_Identity=38.7096774193548, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788481, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788297, Length=190, Percent_Identity=24.2105263157895, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=170, Percent_Identity=25.8823529411765, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33439; Mature: 33439

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRQLEVFQAVMQAGNMSAAARLICITPSAVSKTIAHTELQLGYKLFTRGKGTLAPTPE
CCCHHHHHHHHHHHCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
ARVLFEESTVIHCKLDELKRIALNLRQADDGQVRLAAIPSICHEFLPLVLEKHLARYPRV
CEEEEECCEEEEEEHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCE
KIEVRTLHQDQMVQALLTRSVDFALGYYEHPHPLLTSQMLVRGPLYLAVTRDVWLRAVRT
EEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHH
RRLNPMSFLASMPLIRLVGEDPMCQSIDELAGHLGLTAPAGLQVHTSRLALELVKRGMGW
CCCCHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCC
TVVDFLTASNLDPSSISAVALHDFAPIPLQMYFATSTPPGQDALRLLGMLPDLLRGVMAS
CHHHHHHHCCCCCHHHHEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
SH
CC
>Mature Secondary Structure
MNLRQLEVFQAVMQAGNMSAAARLICITPSAVSKTIAHTELQLGYKLFTRGKGTLAPTPE
CCCHHHHHHHHHHHCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
ARVLFEESTVIHCKLDELKRIALNLRQADDGQVRLAAIPSICHEFLPLVLEKHLARYPRV
CEEEEECCEEEEEEHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCE
KIEVRTLHQDQMVQALLTRSVDFALGYYEHPHPLLTSQMLVRGPLYLAVTRDVWLRAVRT
EEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHH
RRLNPMSFLASMPLIRLVGEDPMCQSIDELAGHLGLTAPAGLQVHTSRLALELVKRGMGW
CCCCHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCC
TVVDFLTASNLDPSSISAVALHDFAPIPLQMYFATSTPPGQDALRLLGMLPDLLRGVMAS
CHHHHHHHCCCCCHHHHEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
SH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350602; 9278503; 2836407 [H]