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The map label for this gene is gmhB [H]

Identifier: 91790039

GI number: 91790039

Start: 4418906

End: 4419490

Strand: Reverse

Name: gmhB [H]

Synonym: Bpro_4201

Alternate gene names: 91790039

Gene position: 4419490-4418906 (Counterclockwise)

Preceding gene: 91790040

Following gene: 91790038

Centisome position: 84.99

GC content: 65.3

Gene sequence:

>585_bases
ATGCAAAGCACCATGAAACTCGTCATCCTTGACCGCGACGGCACCATCAACAGCGACAGCGACGACTTCGTCAAGACGCC
GGAGGAATGGCTGCCGCTGCCCGGTGCGCTGGAGGCGATTGCCCGGCTCAACCATGCAGGCTGGCATGTCGTCATTGCAT
CCAACCAGTCAGGCCTGGGGCGGGGCTTGTTTGATGTGGCCTCGCTCAATGCGATACACGCCAAAATGAACAAGATGCTG
GCCGCCCTCGGCGGGCGCGTCGATGCCGTGTTTTACTGTCCGCACAGCCCCGAGGAAAGCTGTAACTGCCGCAAACCGCT
GCCGGGCCTGTTCGAGCAGATTGGCGCGCGTTTTGGTGTGCCACTCAAGGGGGTGCCCACCGCCGGCGATTCCCTGCGCG
ATCTGCTGGCGGGGGCCGCGGCCGGCTGCGAGCCGCACCTGGTGCTCACCGGCAAGTCGGCGCAATACCGCAACGGCGTG
CCGCCCGAAGGCATGCCGCCGGGCACCTTGGTGCATCGCGACCTGTCGGCCTTTGCCGACTTCATCCTGGAGCGCAGTGC
CCGGCCCGCACCAGCGTCGCTATAA

Upstream 100 bases:

>100_bases
CAACCGCCTCGGCCTGCTGGCCACGCTGCACCAGGCCATGAACCGCGTGGCCGACCTGTCCAAGCTGGCAACATGAGCCC
CCTCGCAGTCTGACCCTTCA

Downstream 100 bases:

>100_bases
AGAAGATAGCTGACTGTGCCCGTGAAGTAGGGGTGTAGTGGCTGCAGGCCTTCAGAGAACTTTCAAATTCACCCCGAACG
CCGGAAACACCTGACATGCC

Product: D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MQSTMKLVILDRDGTINSDSDDFVKTPEEWLPLPGALEAIARLNHAGWHVVIASNQSGLGRGLFDVASLNAIHAKMNKML
AALGGRVDAVFYCPHSPEESCNCRKPLPGLFEQIGARFGVPLKGVPTAGDSLRDLLAGAAAGCEPHLVLTGKSAQYRNGV
PPEGMPPGTLVHRDLSAFADFILERSARPAPASL

Sequences:

>Translated_194_residues
MQSTMKLVILDRDGTINSDSDDFVKTPEEWLPLPGALEAIARLNHAGWHVVIASNQSGLGRGLFDVASLNAIHAKMNKML
AALGGRVDAVFYCPHSPEESCNCRKPLPGLFEQIGARFGVPLKGVPTAGDSLRDLLAGAAAGCEPHLVLTGKSAQYRNGV
PPEGMPPGTLVHRDLSAFADFILERSARPAPASL
>Mature_194_residues
MQSTMKLVILDRDGTINSDSDDFVKTPEEWLPLPGALEAIARLNHAGWHVVIASNQSGLGRGLFDVASLNAIHAKMNKML
AALGGRVDAVFYCPHSPEESCNCRKPLPGLFEQIGARFGVPLKGVPTAGDSLRDLLAGAAAGCEPHLVLTGKSAQYRNGV
PPEGMPPGTLVHRDLSAFADFILERSARPAPASL

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=160, Percent_Identity=33.125, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082027, Length=141, Percent_Identity=31.2056737588652, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20589; Mature: 20589

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTMKLVILDRDGTINSDSDDFVKTPEEWLPLPGALEAIARLNHAGWHVVIASNQSGLG
CCCCEEEEEECCCCCCCCCCCHHHCCCHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
RGLFDVASLNAIHAKMNKMLAALGGRVDAVFYCPHSPEESCNCRKPLPGLFEQIGARFGV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
PLKGVPTAGDSLRDLLAGAAAGCEPHLVLTGKSAQYRNGVPPEGMPPGTLVHRDLSAFAD
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHHHH
FILERSARPAPASL
HHHHHCCCCCCCCC
>Mature Secondary Structure
MQSTMKLVILDRDGTINSDSDDFVKTPEEWLPLPGALEAIARLNHAGWHVVIASNQSGLG
CCCCEEEEEECCCCCCCCCCCHHHCCCHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
RGLFDVASLNAIHAKMNKMLAALGGRVDAVFYCPHSPEESCNCRKPLPGLFEQIGARFGV
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
PLKGVPTAGDSLRDLLAGAAAGCEPHLVLTGKSAQYRNGVPPEGMPPGTLVHRDLSAFAD
CCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHHHH
FILERSARPAPASL
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 12101286 [H]