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The map label for this gene is dtd

Identifier: 91789937

GI number: 91789937

Start: 4306643

End: 4307107

Strand: Reverse

Name: dtd

Synonym: Bpro_4098

Alternate gene names: 91789937

Gene position: 4307107-4306643 (Counterclockwise)

Preceding gene: 91789938

Following gene: 91789936

Centisome position: 82.82

GC content: 65.16

Gene sequence:

>465_bases
ATGAAGGCCGTGCTGCAGCGCGTGGCCGAAGCCCGCGTGGTGGTTGCCGGTGAGACCGTGGGCCAGATCGGTCAGGGTTT
GCTGGTGCTGGTGTGCGCCGAACGCGGCGACGCAGAAGGGCAGGCCGACAAGCTGTTGGCCAAGATACTCAAGCTGCGGA
TTTTTTCGGACGAGGCCGGCAAGATGAACCGCAGCGTGCAAGACCTCGATGGCGCAGGCAAGCAGGGCGGCCTGCTCATC
GTGAGCCAGTTCACGCTGGCCGCCGATGTGTCGGGCGGCAACCGGCCCAGCTTCACGGATGCTGCGGCCCCTGATGAGGG
GCGCCGGCTGTACGACTACTTTGTGGCGCAGGCTCTAGCCTTGCATCCCATGGTCCAGACCGGGCAGTTTGCCGCCGACA
TGCAGGTGCACCTGGTCAATGACGGGCCGGTGACCATTCCCTTGCACATCGATCCGGCAGCCTGA

Upstream 100 bases:

>100_bases
GCTGCGTGCGACCATCCAGCTGTTGCCCAGCGATGTGGAGGCCCATTTTGACGACGAGAAAGACCTGATTTGAAATGAGT
GTTGACAAGAGAACGCTGCC

Downstream 100 bases:

>100_bases
CCGGAACGCCGAATGCTATTAATTCAGTAGCGTATTGCGTGTGTTTTACAGGGCTTGCAGACAGCTTTTGCATGAAAAAT
TGAGCGCGCTGGCCGGTGAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKAVLQRVAEARVVVAGETVGQIGQGLLVLVCAERGDAEGQADKLLAKILKLRIFSDEAGKMNRSVQDLDGAGKQGGLLI
VSQFTLAADVSGGNRPSFTDAAAPDEGRRLYDYFVAQALALHPMVQTGQFAADMQVHLVNDGPVTIPLHIDPAA

Sequences:

>Translated_154_residues
MKAVLQRVAEARVVVAGETVGQIGQGLLVLVCAERGDAEGQADKLLAKILKLRIFSDEAGKMNRSVQDLDGAGKQGGLLI
VSQFTLAADVSGGNRPSFTDAAAPDEGRRLYDYFVAQALALHPMVQTGQFAADMQVHLVNDGPVTIPLHIDPAA
>Mature_154_residues
MKAVLQRVAEARVVVAGETVGQIGQGLLVLVCAERGDAEGQADKLLAKILKLRIFSDEAGKMNRSVQDLDGAGKQGGLLI
VSQFTLAADVSGGNRPSFTDAAAPDEGRRLYDYFVAQALALHPMVQTGQFAADMQVHLVNDGPVTIPLHIDPAA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=152, Percent_Identity=42.1052631578947, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790320, Length=150, Percent_Identity=54, Blast_Score=150, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=43.046357615894, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319982, Length=153, Percent_Identity=37.2549019607843, Blast_Score=91, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=41.7218543046358, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_POLSJ (Q124Q1)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550889.1
- ProteinModelPortal:   Q124Q1
- SMR:   Q124Q1
- STRING:   Q124Q1
- GeneID:   4013231
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_4098
- NMPDR:   fig|296591.1.peg.4165
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q124Q1
- ProtClustDB:   PRK05273
- BioCyc:   PSP296591:BPRO_4098-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16235; Mature: 16235

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: ACT_SITE 85-85

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLQRVAEARVVVAGETVGQIGQGLLVLVCAERGDAEGQADKLLAKILKLRIFSDEAG
CHHHHHHHHHCEEEEECCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
KMNRSVQDLDGAGKQGGLLIVSQFTLAADVSGGNRPSFTDAAAPDEGRRLYDYFVAQALA
HHCCCHHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LHPMVQTGQFAADMQVHLVNDGPVTIPLHIDPAA
HHHHHHCCCEECCEEEEEECCCCEEEEEEECCCC
>Mature Secondary Structure
MKAVLQRVAEARVVVAGETVGQIGQGLLVLVCAERGDAEGQADKLLAKILKLRIFSDEAG
CHHHHHHHHHCEEEEECCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
KMNRSVQDLDGAGKQGGLLIVSQFTLAADVSGGNRPSFTDAAAPDEGRRLYDYFVAQALA
HHCCCHHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LHPMVQTGQFAADMQVHLVNDGPVTIPLHIDPAA
HHHHHHCCCEECCEEEEEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA