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The map label for this gene is vipA [H]

Identifier: 91789837

GI number: 91789837

Start: 4192850

End: 4194130

Strand: Reverse

Name: vipA [H]

Synonym: Bpro_3997

Alternate gene names: 91789837

Gene position: 4194130-4192850 (Counterclockwise)

Preceding gene: 91789838

Following gene: 91789836

Centisome position: 80.65

GC content: 61.28

Gene sequence:

>1281_bases
ATGCAAAGTACTTCTCTTGCCCGCACTGTCGCCATCATCGGCCTGGGCTACGTAGGCCTGCCCCTGGCCGTTGAGTTTGG
TAAAAAACGCAAGGTTGTGGGCTTTGACATCAGCGCTGCTCGGGTGGCCGAACTTCAGGCAGGGCAAGACCACACGCTGG
AGGTGGAGCCCGAGCAAATGCGCAAGGCCGTGCACCTGCAGTACACCACCGACCCCGCCGCCCTGCAAGGCTGTGACCTG
TTCATCGTCACCGTGCCCACCCCCATCGACGAATACAAACGCCCCGATCTGACGCCCCTCATCAAGGCCAGTACCACCAT
AGGCAAGGTGCTGAAGAAGGGCGACATCGTCATTTACGAATCTACCGTCTACCCCGGCGCTACCGAGGAGGACTGCGTGC
CCGTGCTGGAGCAGTACTCGGGGCTGAAATTCAATGTCGATTTTTTTGCAGGCTATTCGCCGGAGCGCGTGAACCCGGGT
GACAAGACCCATCGCGTTACCACCATCAAAAAAGTCACGTCCGGCTCCACCCCCGAGGTGGCCGACCTGGTGGATGCGCT
CTACAACGAAATCGTGACTGTTGGCACCCACAAGGCCCCCAGCATCAGGGTGGCCGAGGCGGCCAAGGTGATTGAGAACA
CCCAGCGTGATGTCAACATCGCGCTCATTAATGAACTGGCGCTTATTTTCAACAGGCTCGGCATAGACACCGAAGCCGTG
CTGCAGGCGGCAGGCACCAAGTGGAACTTTTTGCCATTCCGCCCCGGCCTGGTGGGCGGGCACTGCATTGGCGTGGACCC
GTACTACCTCACGCACAAGGCCGAGGCCATTGGCTATCACCCCGAAATCATCCTCGCCGGCCGCCGCCTGAACGACAGCA
TGGGCGCCTACGTGGTCACCCAGCTCGTCAAGGCCATGACAAAGCGCCGCATCCACGTGCGGGGCGCCCGCGTGCTGGTG
ATGGGCCTGGCCTTCAAGGAAAACTGCCCAGACCTGCGCAACACCCGCGTGGTAGACATCGTGCGGGAGCTCACCGACTA
CGACGTGCAAGCCGATGTGCACGACCCCTGGGTTTCGGTCGAAGAGGCGCAGCTCGAATACGGCATCACCCCGGTGCGGC
AGCCTGAAGGCGGAACTTACGACGCCATCATCGTCGCCGTGGCGCACGAGCAGTTCAAGGCCATGGGCGCCGCTGCCTTT
CGTGCCTTGGGTAAGCCCGAGCACGTGTTGTTTGACCTGAAGTACGTGCTGACGGCGTCTGAGAGCGACCTGCGGTTATG
A

Upstream 100 bases:

>100_bases
GAAGGAGCTAAAGCAGCAGGCGCTTGATCTGGTGCAAAACAGACTTGTGTATAACGGCATGTCTTGACGGCTACTTTTAG
TGTCATAAAAAATTCTTCCT

Downstream 100 bases:

>100_bases
AAACGCGCGCCACGTCCATAATTTGCCTGGTCCAGTGGTCAATCCGTGGGCAAATAGCGAGTGAAAAATGCTTTCTGCCC
TTTCCATTTGAGTGCAGGTA

Product: UDP-glucose/GDP-mannose dehydrogenase

Products: UDP-N-acetyl-D-mannosaminuronic-acid; NADH; Proton [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MQSTSLARTVAIIGLGYVGLPLAVEFGKKRKVVGFDISAARVAELQAGQDHTLEVEPEQMRKAVHLQYTTDPAALQGCDL
FIVTVPTPIDEYKRPDLTPLIKASTTIGKVLKKGDIVIYESTVYPGATEEDCVPVLEQYSGLKFNVDFFAGYSPERVNPG
DKTHRVTTIKKVTSGSTPEVADLVDALYNEIVTVGTHKAPSIRVAEAAKVIENTQRDVNIALINELALIFNRLGIDTEAV
LQAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAEAIGYHPEIILAGRRLNDSMGAYVVTQLVKAMTKRRIHVRGARVLV
MGLAFKENCPDLRNTRVVDIVRELTDYDVQADVHDPWVSVEEAQLEYGITPVRQPEGGTYDAIIVAVAHEQFKAMGAAAF
RALGKPEHVLFDLKYVLTASESDLRL

Sequences:

>Translated_426_residues
MQSTSLARTVAIIGLGYVGLPLAVEFGKKRKVVGFDISAARVAELQAGQDHTLEVEPEQMRKAVHLQYTTDPAALQGCDL
FIVTVPTPIDEYKRPDLTPLIKASTTIGKVLKKGDIVIYESTVYPGATEEDCVPVLEQYSGLKFNVDFFAGYSPERVNPG
DKTHRVTTIKKVTSGSTPEVADLVDALYNEIVTVGTHKAPSIRVAEAAKVIENTQRDVNIALINELALIFNRLGIDTEAV
LQAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAEAIGYHPEIILAGRRLNDSMGAYVVTQLVKAMTKRRIHVRGARVLV
MGLAFKENCPDLRNTRVVDIVRELTDYDVQADVHDPWVSVEEAQLEYGITPVRQPEGGTYDAIIVAVAHEQFKAMGAAAF
RALGKPEHVLFDLKYVLTASESDLRL
>Mature_426_residues
MQSTSLARTVAIIGLGYVGLPLAVEFGKKRKVVGFDISAARVAELQAGQDHTLEVEPEQMRKAVHLQYTTDPAALQGCDL
FIVTVPTPIDEYKRPDLTPLIKASTTIGKVLKKGDIVIYESTVYPGATEEDCVPVLEQYSGLKFNVDFFAGYSPERVNPG
DKTHRVTTIKKVTSGSTPEVADLVDALYNEIVTVGTHKAPSIRVAEAAKVIENTQRDVNIALINELALIFNRLGIDTEAV
LQAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAEAIGYHPEIILAGRRLNDSMGAYVVTQLVKAMTKRRIHVRGARVLV
MGLAFKENCPDLRNTRVVDIVRELTDYDVQADVHDPWVSVEEAQLEYGITPVRQPEGGTYDAIIVAVAHEQFKAMGAAAF
RALGKPEHVLFDLKYVLTASESDLRL

Specific function: Catalyzes The Oxidation Of Udp-Mannac To Udp-N- Acetylmannosaminuronic Acid (Udp-Mannaca). [C]

COG id: COG0677

COG function: function code M; UDP-N-acetyl-D-mannosaminuronate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI48994968, Length=412, Percent_Identity=31.7961165048544, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 46749; Mature: 46749

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSTSLARTVAIIGLGYVGLPLAVEFGKKRKVVGFDISAARVAELQAGQDHTLEVEPEQM
CCCHHHHHHHHHHHCCHHCCCEEEECCCCCEEEEECCCHHHHHHHCCCCCCEEEECHHHH
RKAVHLQYTTDPAALQGCDLFIVTVPTPIDEYKRPDLTPLIKASTTIGKVLKKGDIVIYE
HCEEEEEECCCHHHHCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEE
STVYPGATEEDCVPVLEQYSGLKFNVDFFAGYSPERVNPGDKTHRVTTIKKVTSGSTPEV
CCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCHH
ADLVDALYNEIVTVGTHKAPSIRVAEAAKVIENTQRDVNIALINELALIFNRLGIDTEAV
HHHHHHHHHHEEEECCCCCCCEEHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCHHHH
LQAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAEAIGYHPEIILAGRRLNDSMGAYVVT
HHHCCCCCCEECCCCCCCCCEEECCCCEEEEECHHHCCCCCEEEEECCCCCCCHHHHHHH
QLVKAMTKRRIHVRGARVLVMGLAFKENCPDLRNTRVVDIVRELTDYDVQADVHDPWVSV
HHHHHHHHCEEEECCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCH
EEAQLEYGITPVRQPEGGTYDAIIVAVAHEQFKAMGAAAFRALGKPEHVLFDLKYVLTAS
HHHHHHCCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECC
ESDLRL
CCCCCC
>Mature Secondary Structure
MQSTSLARTVAIIGLGYVGLPLAVEFGKKRKVVGFDISAARVAELQAGQDHTLEVEPEQM
CCCHHHHHHHHHHHCCHHCCCEEEECCCCCEEEEECCCHHHHHHHCCCCCCEEEECHHHH
RKAVHLQYTTDPAALQGCDLFIVTVPTPIDEYKRPDLTPLIKASTTIGKVLKKGDIVIYE
HCEEEEEECCCHHHHCCCCEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEE
STVYPGATEEDCVPVLEQYSGLKFNVDFFAGYSPERVNPGDKTHRVTTIKKVTSGSTPEV
CCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCHH
ADLVDALYNEIVTVGTHKAPSIRVAEAAKVIENTQRDVNIALINELALIFNRLGIDTEAV
HHHHHHHHHHEEEECCCCCCCEEHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCHHHH
LQAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAEAIGYHPEIILAGRRLNDSMGAYVVT
HHHCCCCCCEECCCCCCCCCEEECCCCEEEEECHHHCCCCCEEEEECCCCCCCHHHHHHH
QLVKAMTKRRIHVRGARVLVMGLAFKENCPDLRNTRVVDIVRELTDYDVQADVHDPWVSV
HHHHHHHHCEEEECCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCH
EEAQLEYGITPVRQPEGGTYDAIIVAVAHEQFKAMGAAAFRALGKPEHVLFDLKYVLTAS
HHHHHHCCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECC
ESDLRL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-acetyl-D-mannosamine; NAD [C]

Specific reaction: UDP-N-acetyl-D-mannosamine + NAD = UDP-N-acetyl-D-mannosaminuronic-acid + NADH + Proton [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248629; 8331073; 11677608; 12644504 [H]