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The map label for this gene is siaT [H]

Identifier: 91789806

GI number: 91789806

Start: 4157935

End: 4159329

Strand: Direct

Name: siaT [H]

Synonym: Bpro_3966

Alternate gene names: 91789806

Gene position: 4157935-4159329 (Clockwise)

Preceding gene: 91789805

Following gene: 91789807

Centisome position: 79.96

GC content: 62.44

Gene sequence:

>1395_bases
ATGCTGAAAGTTGCTTTCCTGTTCCTGATGAGCGGCGGCCTGCCGGTGGCCATGGCCATGGCCGGCGCTTCGCTCCTCTA
CATCCTGTTCACCCAAAGCTCGCCGCCCTTTGTGGTGATTCACCGCATGGTCAGCGGCATTGACAGCTTTCCGCTGCTGG
CCGTGCCTTTCTTCATTCTGGCCGGCAACCTGATGAACAACGCCGGCATCACCAACCGCATCTACAACTACGCGCTGGCG
CTGGTGGGCTGGATGAAGGGCGGGCTGGGCCATGTCAACGTCGTGGGCTCGGTGGTGTTTGCCGGCATGAGCGGCACCGC
CATTGCCGACGCGGCCGGTCTGGGCACGATCGAGATCAAGGCCATGAAGGACCACGGCTACAGCACCGAATTTGCCGTGG
GCGTGACGGCGGCTTCCGCCACGCTGGGCCCCATCATTCCGCCCAGCCTGCCCTTTGTGATCTACGGCATGATGGCCAAC
GTCAGTGTTGGCGCCCTGTTTCTGGCCGGCATACTGCCGGGCGTCATGATGGCCATCCTGATGATGCTCACCGTGGCTTA
CTTCGCGCACAAGAACGGCTGGGGCGCCGACGTCAAGTTCGATTGGCGCCGCCTGAGCAAGGCGCTGATCGAAACCGCGG
TGGTCATCGGCTGGCCGCTGCTGCTGTGGCTGCTGATTGGCAAGCTTAACTTTCCGCCGCAAGTCACCGTGGCCGCCGCG
CTGGTGGCGCTGTTTGCGGCCGACAAGGCGTTCAAGTTCCAGGCCGTTCTGCCCATCATGACGCCGGTGCTGCTGATCGG
CGGCATGACGACCGGCATCTTCACGCCCACCGAAGGCGCAATTGCCGCCTGCGTCTGGTCGCTGATCCTCGGCTTTGCCT
GGTATGGCACGTTGACCTTCAAGAGTTTCGTGAAGGTCTGCCTGGATACGGTAGAGACGACAGCCACCGTGCTGTTCATC
GTGGCCGCGGCGTCCATCTTCGGCTGGATGCTCACCGCCACCGGCGTGACCACCGACATTGCCAACTGGGTGCTGGGTTT
CACCAAGGAGGCCTGGGTCTTCCTGCTGCTGGCCAATGTGCTGATGCTGTTTGTGGGCTGCTTCCTGGAGCCGACGGCGG
CCATCACGATTCTGGTGCCCATCCTGGTGCCCATCGCCGTGCAGCTGGGCGTTGACCCCGTCCATTTCGGGCTGGTGATG
GTGCTCAACCTGATGATAGGCCTGCTGCACCCACCCATGGGCATGGTGCTGTTTGTGCTGGCGCGCGTGGCCAAGCTCTC
GGTCGAGCGCACCACCATCGCCATTCTGCCCTGGCTGTTTCCGCTGCTGGGCAGCCTGATTGTCATTACCTACTTCCCCA
AGCTGGTGCTGTGGCTGCCCAAGATGTTTTATTGA

Upstream 100 bases:

>100_bases
TGCGGCCATGTGCGTGCGCTCGGTCTGGGTCATGCATGTGCACGTGAAGCGCGGCTACAGCGTGCTGGAACGCCCTGAAT
CCACCATGGAGGACCGCTAA

Downstream 100 bases:

>100_bases
AATGTTTTGTTGAAATGTTTGACTGAAGAGAAATTTCCATGACCCCATTCATTCGCCTTCATCCCGCCGATGACGTGCTG
ATCGCCCGCCAGCAACTGCT

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MLKVAFLFLMSGGLPVAMAMAGASLLYILFTQSSPPFVVIHRMVSGIDSFPLLAVPFFILAGNLMNNAGITNRIYNYALA
LVGWMKGGLGHVNVVGSVVFAGMSGTAIADAAGLGTIEIKAMKDHGYSTEFAVGVTAASATLGPIIPPSLPFVIYGMMAN
VSVGALFLAGILPGVMMAILMMLTVAYFAHKNGWGADVKFDWRRLSKALIETAVVIGWPLLLWLLIGKLNFPPQVTVAAA
LVALFAADKAFKFQAVLPIMTPVLLIGGMTTGIFTPTEGAIAACVWSLILGFAWYGTLTFKSFVKVCLDTVETTATVLFI
VAAASIFGWMLTATGVTTDIANWVLGFTKEAWVFLLLANVLMLFVGCFLEPTAAITILVPILVPIAVQLGVDPVHFGLVM
VLNLMIGLLHPPMGMVLFVLARVAKLSVERTTIAILPWLFPLLGSLIVITYFPKLVLWLPKMFY

Sequences:

>Translated_464_residues
MLKVAFLFLMSGGLPVAMAMAGASLLYILFTQSSPPFVVIHRMVSGIDSFPLLAVPFFILAGNLMNNAGITNRIYNYALA
LVGWMKGGLGHVNVVGSVVFAGMSGTAIADAAGLGTIEIKAMKDHGYSTEFAVGVTAASATLGPIIPPSLPFVIYGMMAN
VSVGALFLAGILPGVMMAILMMLTVAYFAHKNGWGADVKFDWRRLSKALIETAVVIGWPLLLWLLIGKLNFPPQVTVAAA
LVALFAADKAFKFQAVLPIMTPVLLIGGMTTGIFTPTEGAIAACVWSLILGFAWYGTLTFKSFVKVCLDTVETTATVLFI
VAAASIFGWMLTATGVTTDIANWVLGFTKEAWVFLLLANVLMLFVGCFLEPTAAITILVPILVPIAVQLGVDPVHFGLVM
VLNLMIGLLHPPMGMVLFVLARVAKLSVERTTIAILPWLFPLLGSLIVITYFPKLVLWLPKMFY
>Mature_464_residues
MLKVAFLFLMSGGLPVAMAMAGASLLYILFTQSSPPFVVIHRMVSGIDSFPLLAVPFFILAGNLMNNAGITNRIYNYALA
LVGWMKGGLGHVNVVGSVVFAGMSGTAIADAAGLGTIEIKAMKDHGYSTEFAVGVTAASATLGPIIPPSLPFVIYGMMAN
VSVGALFLAGILPGVMMAILMMLTVAYFAHKNGWGADVKFDWRRLSKALIETAVVIGWPLLLWLLIGKLNFPPQVTVAAA
LVALFAADKAFKFQAVLPIMTPVLLIGGMTTGIFTPTEGAIAACVWSLILGFAWYGTLTFKSFVKVCLDTVETTATVLFI
VAAASIFGWMLTATGVTTDIANWVLGFTKEAWVFLLLANVLMLFVGCFLEPTAAITILVPILVPIAVQLGVDPVHFGLVM
VLNLMIGLLHPPMGMVLFVLARVAKLSVERTTIAILPWLFPLLGSLIVITYFPKLVLWLPKMFY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=447, Percent_Identity=31.5436241610738, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 49611; Mature: 49611

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVAFLFLMSGGLPVAMAMAGASLLYILFTQSSPPFVVIHRMVSGIDSFPLLAVPFFIL
CHHHHHHHHHCCCCHHHHHHHHHHEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHH
AGNLMNNAGITNRIYNYALALVGWMKGGLGHVNVVGSVVFAGMSGTAIADAAGLGTIEIK
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEE
AMKDHGYSTEFAVGVTAASATLGPIIPPSLPFVIYGMMANVSVGALFLAGILPGVMMAIL
EEECCCCCCEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLTVAYFAHKNGWGADVKFDWRRLSKALIETAVVIGWPLLLWLLIGKLNFPPQVTVAAA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVALFAADKAFKFQAVLPIMTPVLLIGGMTTGIFTPTEGAIAACVWSLILGFAWYGTLTF
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSFVKVCLDTVETTATVLFIVAAASIFGWMLTATGVTTDIANWVLGFTKEAWVFLLLANV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
LMLFVGCFLEPTAAITILVPILVPIAVQLGVDPVHFGLVMVLNLMIGLLHPPMGMVLFVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ARVAKLSVERTTIAILPWLFPLLGSLIVITYFPKLVLWLPKMFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKVAFLFLMSGGLPVAMAMAGASLLYILFTQSSPPFVVIHRMVSGIDSFPLLAVPFFIL
CHHHHHHHHHCCCCHHHHHHHHHHEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHH
AGNLMNNAGITNRIYNYALALVGWMKGGLGHVNVVGSVVFAGMSGTAIADAAGLGTIEIK
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEE
AMKDHGYSTEFAVGVTAASATLGPIIPPSLPFVIYGMMANVSVGALFLAGILPGVMMAIL
EEECCCCCCEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMLTVAYFAHKNGWGADVKFDWRRLSKALIETAVVIGWPLLLWLLIGKLNFPPQVTVAAA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVALFAADKAFKFQAVLPIMTPVLLIGGMTTGIFTPTEGAIAACVWSLILGFAWYGTLTF
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KSFVKVCLDTVETTATVLFIVAAASIFGWMLTATGVTTDIANWVLGFTKEAWVFLLLANV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
LMLFVGCFLEPTAAITILVPILVPIAVQLGVDPVHFGLVMVLNLMIGLLHPPMGMVLFVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ARVAKLSVERTTIAILPWLFPLLGSLIVITYFPKLVLWLPKMFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]