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The map label for this gene is garD [H]

Identifier: 91789807

GI number: 91789807

Start: 4159368

End: 4160894

Strand: Direct

Name: garD [H]

Synonym: Bpro_3967

Alternate gene names: 91789807

Gene position: 4159368-4160894 (Clockwise)

Preceding gene: 91789806

Following gene: 91789808

Centisome position: 79.98

GC content: 66.27

Gene sequence:

>1527_bases
ATGACCCCATTCATTCGCCTTCATCCCGCCGATGACGTGCTGATCGCCCGCCAGCAACTGCTGAGCGGCACCAGCGTCGA
AGGTGTACCGGTCAAGGGCCTGATCCCGGCCGGCCACAAGATCGCCACCCACCCCATCGCGCAGGGCGAGCCGGTGCGGC
GCTACAACCAGATCATCGGCTTTGCCAGCAAACCGATTGCCGCCGGTGAGCACGTTCACACGCACAACCTCGACATGGGC
CCGAACAAGGGTGACTTCGAACGCGACTACGCCTTTGGCGCGGACGTCAAACCCGAACCGGCGCGGCGCGAGGCCACCTT
CATGGGCATCAAGCGGGCCGACGGCCGCGTTGCCACGCGCAACTACATCGGCGTGCTCACGAGCGTGAACTGCTCGGCCA
CCGCCGCGCGCGCCATCGCCGACCACTTTTCGCGGCGCACCAACCCGGCGGCGCTGGCCGCGTTCCCGAATGTCGACGGC
GTGGTGGCGCTGACCCACGGCACCGGCTGCGGCATGGACACCGAGGGGACAGGCATGCAGCTGCTGCAGCGCACGCTGGC
CGGTTATGCCACGCACGCCAACTTTGCCGCCGTGCTGGTGGTGGGACTGGGCTGCGAAGCCAACCAGATCAATGCCTGGC
TGGCGCACAGCAGCCTGCGGGAGGGCGAGACCTTCAAGGTGTTCAACATCCAGGACACGGGCGGCACGACCAAGACCGTG
GCCAAGGGCGTCGCCCTGATCAACGAAATGCTGCCCACCGTCAACAACGTGAAGCGCGAACCCTGCAGCGCTGCGCACAT
CACCATCGGCCTGCAATGCGGCGGCTCGGACGGCTACTCGGGCATCAGCGCCAACCCGGCGCTGGGCGCGGCGGTAGACC
TGCTGGTGGCGCACGGCGGCACCGCCATCCTGAGCGAGACACCCGAAATTTACGGTGCGGAACACCTGCTGACGCGCCGG
GCGGTGAAACCCGAGGTGGCTGAAAAGCTGATCCAGCGCATCAAGTGGTGGGAGCACTACACCGAGATCAACGAGGGCGA
GATGAACAACAACCCCTCGCCGGGCAACAAGGCCGGCGGGCTGACCACCATCCTGGAAAAATCGCTGGGCGCCGTCGCCA
AGGGCGGCACCAGCAACCTGCAGGCGGTCTATGAATACGCCGAGCCGGTGCAGGCCCACGGCTTTGTCTACATGGACACG
CCCGGCTACGACCCGGTCAGCGCAACCGGCCAGGTCGCCGGCGGCGCCAACCTGATCTGCTTCACGACCGGCCGCGGCTC
GGCCTATGGCTGCGCACCCTCGCCCTCGCTCAAGCTGTCGACCAACTCGGCGCTGTGGCGCAAGCAGGAAGACGACATGG
ACATCAACTGCGGCGAGATCATCGACGGCAGCAGCACGGTGGCCGAGATGGGGCAGCGCATTTTCGAGCTGGTTCTGGCC
ACCGCGTCAGGCGAACCCAGCAAGAGCGAAAAACACGGCTATGGGCAAAACGAGTTTGTGCCCTGGCAGGTCGGCGCCGT
GATGTAG

Upstream 100 bases:

>100_bases
GCCTGATTGTCATTACCTACTTCCCCAAGCTGGTGCTGTGGCTGCCCAAGATGTTTTATTGAAATGTTTTGTTGAAATGT
TTGACTGAAGAGAAATTTCC

Downstream 100 bases:

>100_bases
TCCTTTTCTTCACTCCCTCTCCCCCTGGGAGAGGGCGGGGGTGAGGGCTCTGCGCGCCGAGAGGCCCTCACCCTGACCCT
CTCCCAGGGGGGAGAGGGAA

Product: Altronate dehydratase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MTPFIRLHPADDVLIARQQLLSGTSVEGVPVKGLIPAGHKIATHPIAQGEPVRRYNQIIGFASKPIAAGEHVHTHNLDMG
PNKGDFERDYAFGADVKPEPARREATFMGIKRADGRVATRNYIGVLTSVNCSATAARAIADHFSRRTNPAALAAFPNVDG
VVALTHGTGCGMDTEGTGMQLLQRTLAGYATHANFAAVLVVGLGCEANQINAWLAHSSLREGETFKVFNIQDTGGTTKTV
AKGVALINEMLPTVNNVKREPCSAAHITIGLQCGGSDGYSGISANPALGAAVDLLVAHGGTAILSETPEIYGAEHLLTRR
AVKPEVAEKLIQRIKWWEHYTEINEGEMNNNPSPGNKAGGLTTILEKSLGAVAKGGTSNLQAVYEYAEPVQAHGFVYMDT
PGYDPVSATGQVAGGANLICFTTGRGSAYGCAPSPSLKLSTNSALWRKQEDDMDINCGEIIDGSSTVAEMGQRIFELVLA
TASGEPSKSEKHGYGQNEFVPWQVGAVM

Sequences:

>Translated_508_residues
MTPFIRLHPADDVLIARQQLLSGTSVEGVPVKGLIPAGHKIATHPIAQGEPVRRYNQIIGFASKPIAAGEHVHTHNLDMG
PNKGDFERDYAFGADVKPEPARREATFMGIKRADGRVATRNYIGVLTSVNCSATAARAIADHFSRRTNPAALAAFPNVDG
VVALTHGTGCGMDTEGTGMQLLQRTLAGYATHANFAAVLVVGLGCEANQINAWLAHSSLREGETFKVFNIQDTGGTTKTV
AKGVALINEMLPTVNNVKREPCSAAHITIGLQCGGSDGYSGISANPALGAAVDLLVAHGGTAILSETPEIYGAEHLLTRR
AVKPEVAEKLIQRIKWWEHYTEINEGEMNNNPSPGNKAGGLTTILEKSLGAVAKGGTSNLQAVYEYAEPVQAHGFVYMDT
PGYDPVSATGQVAGGANLICFTTGRGSAYGCAPSPSLKLSTNSALWRKQEDDMDINCGEIIDGSSTVAEMGQRIFELVLA
TASGEPSKSEKHGYGQNEFVPWQVGAVM
>Mature_507_residues
TPFIRLHPADDVLIARQQLLSGTSVEGVPVKGLIPAGHKIATHPIAQGEPVRRYNQIIGFASKPIAAGEHVHTHNLDMGP
NKGDFERDYAFGADVKPEPARREATFMGIKRADGRVATRNYIGVLTSVNCSATAARAIADHFSRRTNPAALAAFPNVDGV
VALTHGTGCGMDTEGTGMQLLQRTLAGYATHANFAAVLVVGLGCEANQINAWLAHSSLREGETFKVFNIQDTGGTTKTVA
KGVALINEMLPTVNNVKREPCSAAHITIGLQCGGSDGYSGISANPALGAAVDLLVAHGGTAILSETPEIYGAEHLLTRRA
VKPEVAEKLIQRIKWWEHYTEINEGEMNNNPSPGNKAGGLTTILEKSLGAVAKGGTSNLQAVYEYAEPVQAHGFVYMDTP
GYDPVSATGQVAGGANLICFTTGRGSAYGCAPSPSLKLSTNSALWRKQEDDMDINCGEIIDGSSTVAEMGQRIFELVLAT
ASGEPSKSEKHGYGQNEFVPWQVGAVM

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=491, Percent_Identity=35.4378818737271, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI1789475, Length=502, Percent_Identity=34.0637450199203, Blast_Score=271, Evalue=9e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 53728; Mature: 53597

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPFIRLHPADDVLIARQQLLSGTSVEGVPVKGLIPAGHKIATHPIAQGEPVRRYNQIIG
CCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHC
FASKPIAAGEHVHTHNLDMGPNKGDFERDYAFGADVKPEPARREATFMGIKRADGRVATR
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCEEEC
NYIGVLTSVNCSATAARAIADHFSRRTNPAALAAFPNVDGVVALTHGTGCGMDTEGTGMQ
CEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHH
LLQRTLAGYATHANFAAVLVVGLGCEANQINAWLAHSSLREGETFKVFNIQDTGGTTKTV
HHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHH
AKGVALINEMLPTVNNVKREPCSAAHITIGLQCGGSDGYSGISANPALGAAVDLLVAHGG
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCC
TAILSETPEIYGAEHLLTRRAVKPEVAEKLIQRIKWWEHYTEINEGEMNNNPSPGNKAGG
EEEECCCCHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LTTILEKSLGAVAKGGTSNLQAVYEYAEPVQAHGFVYMDTPGYDPVSATGQVAGGANLIC
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCEEEECCCCCCCCCCCCCCCCCCEEEE
FTTGRGSAYGCAPSPSLKLSTNSALWRKQEDDMDINCGEIIDGSSTVAEMGQRIFELVLA
EECCCCCCCCCCCCCCEEEECCCHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
TASGEPSKSEKHGYGQNEFVPWQVGAVM
HCCCCCCCCCCCCCCCCCCCCEECCCCC
>Mature Secondary Structure 
TPFIRLHPADDVLIARQQLLSGTSVEGVPVKGLIPAGHKIATHPIAQGEPVRRYNQIIG
CCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHC
FASKPIAAGEHVHTHNLDMGPNKGDFERDYAFGADVKPEPARREATFMGIKRADGRVATR
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCEEEC
NYIGVLTSVNCSATAARAIADHFSRRTNPAALAAFPNVDGVVALTHGTGCGMDTEGTGMQ
CEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHH
LLQRTLAGYATHANFAAVLVVGLGCEANQINAWLAHSSLREGETFKVFNIQDTGGTTKTV
HHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHH
AKGVALINEMLPTVNNVKREPCSAAHITIGLQCGGSDGYSGISANPALGAAVDLLVAHGG
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCC
TAILSETPEIYGAEHLLTRRAVKPEVAEKLIQRIKWWEHYTEINEGEMNNNPSPGNKAGG
EEEECCCCHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LTTILEKSLGAVAKGGTSNLQAVYEYAEPVQAHGFVYMDTPGYDPVSATGQVAGGANLIC
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHCCEEEECCCCCCCCCCCCCCCCCCEEEE
FTTGRGSAYGCAPSPSLKLSTNSALWRKQEDDMDINCGEIIDGSSTVAEMGQRIFELVLA
EECCCCCCCCCCCCCCEEEECCCHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHH
TASGEPSKSEKHGYGQNEFVPWQVGAVM
HCCCCCCCCCCCCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]