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The map label for this gene is lysN [H]

Identifier: 91789791

GI number: 91789791

Start: 4141045

End: 4142310

Strand: Direct

Name: lysN [H]

Synonym: Bpro_3951

Alternate gene names: 91789791

Gene position: 4141045-4142310 (Clockwise)

Preceding gene: 91789790

Following gene: 91789792

Centisome position: 79.63

GC content: 68.8

Gene sequence:

>1266_bases
ATGAGCGCAGCCGCGCGCACGCCGGTCCGCCCGCTCTATGCGCAGGCCAGCGGCTCGCCGATTCGTGCCATGCTGGCACT
GGCCGGACAGCCCGGCATGATTTCACTGGCAGGCGGTCATCCCGACCCCGCGCTGCTGCCGGCGGACTGGCTGCGCGAAT
GCATGCTGGCCGTGGCCTCCGGCCTGCAGGGGCACAGCCTGCAATACGGTGCCACCGAGGGCCTGCCCGCGCTGCGTGCG
GCCAGCGCCGAGCTGCTGCAACAACGCGGCCTGCAGGCCCAGGCCGAGCAAGTGGTGATCACCACCGGCTCGCAGCAGGC
CATTGACCTGCTGGCGCGGGTTCTCGTCGAGCCGGGCGCCGGCGTGGCGGTGGAGTCCTTCAACTACCCGGCCGCCCTGC
AGGCCTTCCGCTTTGCGGGTGCGCAGCTGGTGGAAGTTCCTGCCGATGCCCAGGGGCTGGATGTCGAGCGGCTCGAAAGT
GTTTTGACCAGCGCACGGCCGCGCGTGCTGTATGTGGTTCCGAACTTTGCCAACCCGACAGGTGCCGTGATGCCCCTGGC
GCGGCGCGTGCGCCTGCTGGAACTTGCCGCACGGCACGAGGTCACACTGATCGAGGACGATCCTTATGGCGAACTCTGGT
TTGGAGCGGCGCCACCGCCCTCGCTGGCGCAGATCAACCAGCAAACCGGATCACATGCGCAGGTAGCCTACATGACGAGT
TATTCCAAGGTGGTGGCCCCGGCCCTGCGCCTGGGTGTGCTGATGGCGCCGCCGGACGTGCTGCGCGCCGTCGTGCTGGC
CAAGCAGGCCGCCGATGTGCACAGCGGCTCACTGGAGCAGCTGACCCTGACCGCGATGCTGGCCTCCAGCCGCCTGGTTG
AGCACCTGGCCATGCTGCGCAAGGCCTACGCGGCCAAGGCCCGCACGCTGGCTGCTGCACTGCACGCACATTGCGGCGGG
CTGCTTGAATTCAGCGAGCCCCAGGGCGGCATGTTTGTCTGGGCCCGGCTTGCCAGCGCGTTGCCACTGATGCCGTCGCA
GGCGTGGGTGGACTTCGGCCTGCAGCACCAGGTGCTGGCCGTGCCGGGCGCCGCCTTCAGCCTTCACAACACCGCACAGC
CCTGGCTGCGCCTGAGTTTTGCCAACCCCGGTGCAGACGCCCTGCTGCAAGGCGCGCAACGCCTGGGCCGCGGGCTGCGC
AGCCTTGCCGCCACGGCCGATACGCCATCATCACGCCAACATTTCCCCGAAAGGACTTCACCATGA

Upstream 100 bases:

>100_bases
GGCATTTTCGGCATGACGGCGGCCCGCGCATGAGCCGCCGGGCCGCTCCCAAGGCCACTCCCAAGGCGAACACCGGAGCG
CTTAGCGCGGAGGTTCACCC

Downstream 100 bases:

>100_bases
GCCACGCCAATGACATTTCGTCCCTGCTGCAAAGCCTGGGCATCCACGCCGACCTGAACAGCCAGGCGTCCGCGACCCTT
GAGGTTCACACCCCGATTGA

Product: class I/II aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSAAARTPVRPLYAQASGSPIRAMLALAGQPGMISLAGGHPDPALLPADWLRECMLAVASGLQGHSLQYGATEGLPALRA
ASAELLQQRGLQAQAEQVVITTGSQQAIDLLARVLVEPGAGVAVESFNYPAALQAFRFAGAQLVEVPADAQGLDVERLES
VLTSARPRVLYVVPNFANPTGAVMPLARRVRLLELAARHEVTLIEDDPYGELWFGAAPPPSLAQINQQTGSHAQVAYMTS
YSKVVAPALRLGVLMAPPDVLRAVVLAKQAADVHSGSLEQLTLTAMLASSRLVEHLAMLRKAYAAKARTLAAALHAHCGG
LLEFSEPQGGMFVWARLASALPLMPSQAWVDFGLQHQVLAVPGAAFSLHNTAQPWLRLSFANPGADALLQGAQRLGRGLR
SLAATADTPSSRQHFPERTSP

Sequences:

>Translated_421_residues
MSAAARTPVRPLYAQASGSPIRAMLALAGQPGMISLAGGHPDPALLPADWLRECMLAVASGLQGHSLQYGATEGLPALRA
ASAELLQQRGLQAQAEQVVITTGSQQAIDLLARVLVEPGAGVAVESFNYPAALQAFRFAGAQLVEVPADAQGLDVERLES
VLTSARPRVLYVVPNFANPTGAVMPLARRVRLLELAARHEVTLIEDDPYGELWFGAAPPPSLAQINQQTGSHAQVAYMTS
YSKVVAPALRLGVLMAPPDVLRAVVLAKQAADVHSGSLEQLTLTAMLASSRLVEHLAMLRKAYAAKARTLAAALHAHCGG
LLEFSEPQGGMFVWARLASALPLMPSQAWVDFGLQHQVLAVPGAAFSLHNTAQPWLRLSFANPGADALLQGAQRLGRGLR
SLAATADTPSSRQHFPERTSP
>Mature_420_residues
SAAARTPVRPLYAQASGSPIRAMLALAGQPGMISLAGGHPDPALLPADWLRECMLAVASGLQGHSLQYGATEGLPALRAA
SAELLQQRGLQAQAEQVVITTGSQQAIDLLARVLVEPGAGVAVESFNYPAALQAFRFAGAQLVEVPADAQGLDVERLESV
LTSARPRVLYVVPNFANPTGAVMPLARRVRLLELAARHEVTLIEDDPYGELWFGAAPPPSLAQINQQTGSHAQVAYMTSY
SKVVAPALRLGVLMAPPDVLRAVVLAKQAADVHSGSLEQLTLTAMLASSRLVEHLAMLRKAYAAKARTLAAALHAHCGGL
LEFSEPQGGMFVWARLASALPLMPSQAWVDFGLQHQVLAVPGAAFSLHNTAQPWLRLSFANPGADALLQGAQRLGRGLRS
LAATADTPSSRQHFPERTSP

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=417, Percent_Identity=27.0983213429257, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI33469970, Length=417, Percent_Identity=27.0983213429257, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1790797, Length=380, Percent_Identity=27.6315789473684, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787710, Length=405, Percent_Identity=26.9135802469136, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=23.6040609137056, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321929, Length=411, Percent_Identity=23.8442822384428, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321000, Length=443, Percent_Identity=23.9277652370203, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321236, Length=470, Percent_Identity=22.1276595744681, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356535, Length=404, Percent_Identity=24.7524752475248, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 44447; Mature: 44315

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAARTPVRPLYAQASGSPIRAMLALAGQPGMISLAGGHPDPALLPADWLRECMLAVAS
CCCCCCCCCCHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
GLQGHSLQYGATEGLPALRAASAELLQQRGLQAQAEQVVITTGSQQAIDLLARVLVEPGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCC
GVAVESFNYPAALQAFRFAGAQLVEVPADAQGLDVERLESVLTSARPRVLYVVPNFANPT
CEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
GAVMPLARRVRLLELAARHEVTLIEDDPYGELWFGAAPPPSLAQINQQTGSHAQVAYMTS
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCCCHHHHHHHCCCCCEEEEEEHH
YSKVVAPALRLGVLMAPPDVLRAVVLAKQAADVHSGSLEQLTLTAMLASSRLVEHLAMLR
HHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KAYAAKARTLAAALHAHCGGLLEFSEPQGGMFVWARLASALPLMPSQAWVDFGLQHQVLA
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCEEEE
VPGAAFSLHNTAQPWLRLSFANPGADALLQGAQRLGRGLRSLAATADTPSSRQHFPERTS
CCCCCEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCC
P
C
>Mature Secondary Structure 
SAAARTPVRPLYAQASGSPIRAMLALAGQPGMISLAGGHPDPALLPADWLRECMLAVAS
CCCCCCCCCHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
GLQGHSLQYGATEGLPALRAASAELLQQRGLQAQAEQVVITTGSQQAIDLLARVLVEPGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCC
GVAVESFNYPAALQAFRFAGAQLVEVPADAQGLDVERLESVLTSARPRVLYVVPNFANPT
CEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCC
GAVMPLARRVRLLELAARHEVTLIEDDPYGELWFGAAPPPSLAQINQQTGSHAQVAYMTS
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCCCHHHHHHHCCCCCEEEEEEHH
YSKVVAPALRLGVLMAPPDVLRAVVLAKQAADVHSGSLEQLTLTAMLASSRLVEHLAMLR
HHHHHHHHHHHCEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KAYAAKARTLAAALHAHCGGLLEFSEPQGGMFVWARLASALPLMPSQAWVDFGLQHQVLA
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCEEEE
VPGAAFSLHNTAQPWLRLSFANPGADALLQGAQRLGRGLRSLAATADTPSSRQHFPERTS
CCCCCEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA