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The map label for this gene is pldh-t [H]

Identifier: 91789771

GI number: 91789771

Start: 4121566

End: 4122393

Strand: Reverse

Name: pldh-t [H]

Synonym: Bpro_3931

Alternate gene names: 91789771

Gene position: 4122393-4121566 (Counterclockwise)

Preceding gene: 91789772

Following gene: 91789769

Centisome position: 79.27

GC content: 63.53

Gene sequence:

>828_bases
ATGAATCTCAAAGGCAAGACCCTCTTCATCACCGGTGCCTCGCGCGGCATCGGGCTGGCCATCGGCAACCGGGCCGCCGC
CGACGGCGCCAATGTGGTCATCGTGGCCAAGACCACCGATGCCAACCCCAAGCTGCCCGGCACCATCTACAGCGCCGCCG
AAGAAATCCGGGCCTCTGGCGGCCAGGCGCTGGCGCTGGCTGTGGACATCCGCGACGAAGACGCCGTGAGAGTCGCCGTG
GTCAAGGCCGTGGAGACTTTTGGCGGCATCGACATCCTGGTCAACAACGCCAGCGCCATCAGCCTCACCGACACCGAGCA
CACGCCGATGAAGCGCTACGACCTGATGAACGGCGTCAATGCGCGCGGCACCTACCTGTGCACGCAGGCCTGCCTGGCCG
AGCTGAAAAAATCCGCGCAGGCCGGGCGCAACCCGCATGTGCTGACGATGTCGCCGCCGCTGTCGATGAAGCCGCACTGG
TTTGAGCACCACACGGCCTACACCATGGCCAAGTACGGCATGAGCATGTGCACGCTGGGGCATGCGGGCGAGTTCGGGAA
GTACGGCATCGCCGTCAACAGCCTGTGGCCGCGCACCGCCATTGCCACCGCCGCGCTGCAGATGCTGCCCGGGGTGGACG
TGAAGCGCTGCCGAACGCCCGAGATCCTGTCTGACGCTGCCTACCTGATCCTGACCAGCCCGAGTTCGAACACCGGCAAT
TTTTATATTGACGACGAACTGCTGGCCGCACACGGCATCACCGACCTGGAAAAATATTCGGTGACCCCGGGAACGAAAGA
CTTCATTCCGGATTTCTTCGTGGATTGA

Upstream 100 bases:

>100_bases
GGGCCTTATCAAGAACAAAGCAAGAACAAAGGCCGGTCTCCGCTGTCGATATGGGGTGGTGAGCTATCAAACATATAGCA
AGTTAAAACAGGAGACGTTC

Downstream 100 bases:

>100_bases
GCATCAGAAAACGGCCAATTCTGTTGAAAAGCTCGCTTTGAGGCGTGTCATCGTTGTCGTGCACGCAAAAGCGCACCTCC
AGCGTGCCGGCCAGGAAGGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: tPLDH [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MNLKGKTLFITGASRGIGLAIGNRAAADGANVVIVAKTTDANPKLPGTIYSAAEEIRASGGQALALAVDIRDEDAVRVAV
VKAVETFGGIDILVNNASAISLTDTEHTPMKRYDLMNGVNARGTYLCTQACLAELKKSAQAGRNPHVLTMSPPLSMKPHW
FEHHTAYTMAKYGMSMCTLGHAGEFGKYGIAVNSLWPRTAIATAALQMLPGVDVKRCRTPEILSDAAYLILTSPSSNTGN
FYIDDELLAAHGITDLEKYSVTPGTKDFIPDFFVD

Sequences:

>Translated_275_residues
MNLKGKTLFITGASRGIGLAIGNRAAADGANVVIVAKTTDANPKLPGTIYSAAEEIRASGGQALALAVDIRDEDAVRVAV
VKAVETFGGIDILVNNASAISLTDTEHTPMKRYDLMNGVNARGTYLCTQACLAELKKSAQAGRNPHVLTMSPPLSMKPHW
FEHHTAYTMAKYGMSMCTLGHAGEFGKYGIAVNSLWPRTAIATAALQMLPGVDVKRCRTPEILSDAAYLILTSPSSNTGN
FYIDDELLAAHGITDLEKYSVTPGTKDFIPDFFVD
>Mature_275_residues
MNLKGKTLFITGASRGIGLAIGNRAAADGANVVIVAKTTDANPKLPGTIYSAAEEIRASGGQALALAVDIRDEDAVRVAV
VKAVETFGGIDILVNNASAISLTDTEHTPMKRYDLMNGVNARGTYLCTQACLAELKKSAQAGRNPHVLTMSPPLSMKPHW
FEHHTAYTMAKYGMSMCTLGHAGEFGKYGIAVNSLWPRTAIATAALQMLPGVDVKRCRTPEILSDAAYLILTSPSSNTGN
FYIDDELLAAHGITDLEKYSVTPGTKDFIPDFFVD

Specific function: Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Oxidizes pyridoxal to 4-pyridoxolactone, but does not have activity toward pyridoxal 5'-phosphate, pyridoxine, pyridoxamine, pyridoxamine 5'-phosphat

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254986, Length=275, Percent_Identity=58.5454545454545, Blast_Score=306, Evalue=9e-84,
Organism=Homo sapiens, GI209862901, Length=204, Percent_Identity=29.9019607843137, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI19923983, Length=204, Percent_Identity=29.9019607843137, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI87082100, Length=196, Percent_Identity=31.6326530612245, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789208, Length=226, Percent_Identity=28.3185840707965, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=27.3764258555133, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790717, Length=197, Percent_Identity=25.8883248730964, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=272, Percent_Identity=58.0882352941177, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17558628, Length=272, Percent_Identity=60.6617647058823, Blast_Score=309, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI17544670, Length=236, Percent_Identity=27.5423728813559, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=283, Percent_Identity=25.4416961130742, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=202, Percent_Identity=28.2178217821782, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI21357673, Length=277, Percent_Identity=60.6498194945848, Blast_Score=329, Evalue=1e-90,
Organism=Drosophila melanogaster, GI21357041, Length=213, Percent_Identity=31.924882629108, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=197, Percent_Identity=30.9644670050761, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=30.8080808080808, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.107 [H]

Molecular weight: Translated: 29336; Mature: 29336

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKGKTLFITGASRGIGLAIGNRAAADGANVVIVAKTTDANPKLPGTIYSAAEEIRASG
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
GQALALAVDIRDEDAVRVAVVKAVETFGGIDILVNNASAISLTDTEHTPMKRYDLMNGVN
CCEEEEEEEECCCCCEEHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCHHHHHHHCCCC
ARGTYLCTQACLAELKKSAQAGRNPHVLTMSPPLSMKPHWFEHHTAYTMAKYGMSMCTLG
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCHHEEECC
HAGEFGKYGIAVNSLWPRTAIATAALQMLPGVDVKRCRTPEILSDAAYLILTSPSSNTGN
CCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCHHHCCCEEEEEECCCCCCCC
FYIDDELLAAHGITDLEKYSVTPGTKDFIPDFFVD
EEECCHHHHHCCCCCHHHEECCCCCHHCCCHHHCC
>Mature Secondary Structure
MNLKGKTLFITGASRGIGLAIGNRAAADGANVVIVAKTTDANPKLPGTIYSAAEEIRASG
CCCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
GQALALAVDIRDEDAVRVAVVKAVETFGGIDILVNNASAISLTDTEHTPMKRYDLMNGVN
CCEEEEEEEECCCCCEEHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCHHHHHHHCCCC
ARGTYLCTQACLAELKKSAQAGRNPHVLTMSPPLSMKPHWFEHHTAYTMAKYGMSMCTLG
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCHHEEECC
HAGEFGKYGIAVNSLWPRTAIATAALQMLPGVDVKRCRTPEILSDAAYLILTSPSSNTGN
CCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCHHHCCCEEEEEECCCCCCCC
FYIDDELLAAHGITDLEKYSVTPGTKDFIPDFFVD
EEECCHHHHHCCCCCHHHEECCCCCHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]