BacMap

Definition	Polaromonas sp. JS666 chromosome, complete genome.
Accession	NC_007948
Length	5,200,264

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The map label for this gene is pldh-t [H]

Identifier: 91789539

GI number: 91789539

Start: 3904022

End: 3904792

Strand: Reverse

Name: pldh-t [H]

Synonym: Bpro_3692

Alternate gene names: 91789539

Gene position: 3904792-3904022 (Counterclockwise)

Preceding gene: 91789541

Following gene: 91789538

Centisome position: 75.09

GC content: 67.44

Gene sequence:

>771_bases
ATGGTCGCGCATAGCCAGCAAGGACTTGTGCAGGGCCGCCGCATCCTGGTGACCGGTGCGGCCCGCGGTTTGGGTTTTTC
CTTTGCCCGCACGCTGTGCGAGAGCGGCGCCCGGGTGGTGCTGGCCGATCTGCGCGAGGAGTTGCTGCAGCAGTCCGTTG
CAACCCTGCGCGCAGAAGGCTTTGACGCCAGCGGCGTGGCGGTGGATGTGGGCGACCCGGCATCGATCCAGTGCTGCGCC
GAGCAGGCGGTGGCCAACCTGGGCGGCCTGGACGGTCTCGTCAACAACGCCGCGGTGACCGACTCCGGAGGTCGCGGCAT
GGACGACATCGAGATCGCCAAGTGGGACCAGGTGATGAACGTCAACGTGCGCGGCACCTGGCTCATGACGCGTGCCTGTC
GCCCCGCGCTGCGCGCCGGTGGCCGCGGCGCCATTGTCAACCTGGCTTCAGATACTGCGATGTGGGGTGCGCCCAATCTG
CTGGCCTATGTGGCCAGCAAGGGCGCCGTGATTGCGATGACGCATTCGCTGGCCCGCGAGCTGGGCCCCGACAACATCAC
CGTCAATGCCATCGCCCCCGGCTTGGTGTTGGTGGAAGCCACGCAGTACGTGCCCGAGTCGCGGCACCGTCAATACATCG
ACCAGCGCGCGCTCCAGCGCGAGCAGATGCCCGAGGACGTCTCCGGCGCGGTGCTCTATGCGCTATCCGATCTGGCCCGG
TTCGTCACCGGCCAGGTTCTCGCCGTCAATGGCGGCTTCGTCATGCGCTGA

Upstream 100 bases:

>100_bases
CTTCAGTTGAGGTTTCTCATGTTTGAAATCATCCGCATCACCGGCCTTCCACGCAGTTTGAGGCATCAGGCCCGCAAGCA
AGCCCGCAGGGAGGTGAACC

Downstream 100 bases:

>100_bases
ACGCGCAAAACCCGAAAAACCCGCTAAACGCAATTTCAAAGGAGTGAACAATGAGTGATCTGTCTGAGCAACGGCAACTC
CCCAAAAGCTGGGACCAACC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: tPLDH [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MVAHSQQGLVQGRRILVTGAARGLGFSFARTLCESGARVVLADLREELLQQSVATLRAEGFDASGVAVDVGDPASIQCCA
EQAVANLGGLDGLVNNAAVTDSGGRGMDDIEIAKWDQVMNVNVRGTWLMTRACRPALRAGGRGAIVNLASDTAMWGAPNL
LAYVASKGAVIAMTHSLARELGPDNITVNAIAPGLVLVEATQYVPESRHRQYIDQRALQREQMPEDVSGAVLYALSDLAR
FVTGQVLAVNGGFVMR

Sequences:

>Translated_256_residues
MVAHSQQGLVQGRRILVTGAARGLGFSFARTLCESGARVVLADLREELLQQSVATLRAEGFDASGVAVDVGDPASIQCCA
EQAVANLGGLDGLVNNAAVTDSGGRGMDDIEIAKWDQVMNVNVRGTWLMTRACRPALRAGGRGAIVNLASDTAMWGAPNL
LAYVASKGAVIAMTHSLARELGPDNITVNAIAPGLVLVEATQYVPESRHRQYIDQRALQREQMPEDVSGAVLYALSDLAR
FVTGQVLAVNGGFVMR
>Mature_256_residues
MVAHSQQGLVQGRRILVTGAARGLGFSFARTLCESGARVVLADLREELLQQSVATLRAEGFDASGVAVDVGDPASIQCCA
EQAVANLGGLDGLVNNAAVTDSGGRGMDDIEIAKWDQVMNVNVRGTWLMTRACRPALRAGGRGAIVNLASDTAMWGAPNL
LAYVASKGAVIAMTHSLARELGPDNITVNAIAPGLVLVEATQYVPESRHRQYIDQRALQREQMPEDVSGAVLYALSDLAR
FVTGQVLAVNGGFVMR

Specific function: Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Oxidizes pyridoxal to 4-pyridoxolactone, but does not have activity toward pyridoxal 5'-phosphate, pyridoxine, pyridoxamine, pyridoxamine 5'-phosphat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=34.9794238683128, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=30.6451612903226, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI126723191, Length=176, Percent_Identity=36.9318181818182, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=30.0813008130081, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=33.6, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=30.952380952381, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=30.6532663316583, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=30.9160305343511, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=28.6290322580645, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=28.90625, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=30.5676855895196, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI142976729, Length=191, Percent_Identity=29.8429319371728, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=27.6150627615063, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40254986, Length=196, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542939, Length=223, Percent_Identity=30.4932735426009, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI302344755, Length=110, Percent_Identity=39.0909090909091, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=31.1004784688995, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=27.807486631016, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=28.2722513089005, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=26.5625, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=29.2553191489362, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI44680136, Length=223, Percent_Identity=29.5964125560538, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI44680133, Length=223, Percent_Identity=29.5964125560538, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI17738292, Length=223, Percent_Identity=29.5964125560538, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI32455239, Length=194, Percent_Identity=29.8969072164948, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI5031765, Length=194, Percent_Identity=29.8969072164948, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4504505, Length=232, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=33.596837944664, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=31.3492063492063, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=30.0813008130081, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=31.1284046692607, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=30.2040816326531, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=28.8461538461538, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=28.6852589641434, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=30.8, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=26.8595041322314, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787526, Length=257, Percent_Identity=29.9610894941634, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=26.4822134387352, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=27.9527559055118, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=225, Percent_Identity=29.3333333333333, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787891, Length=254, Percent_Identity=25.9842519685039, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=209, Percent_Identity=29.1866028708134, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=31.6, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=28.5714285714286, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=30.2788844621514, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=32.9317269076305, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=31.1475409836066, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=33.1658291457286, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=28.8617886178862, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=27.9352226720648, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=27.6515151515151, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=28.0155642023346, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558628, Length=202, Percent_Identity=30.6930693069307, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=26.171875, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=271, Percent_Identity=29.1512915129151, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=28.8461538461538, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=175, Percent_Identity=30.2857142857143, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=27.4809160305344, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=172, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=29.3814432989691, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=27.0992366412214, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.2030651340996, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=187, Percent_Identity=31.5508021390374, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=169, Percent_Identity=26.6272189349112, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=26.8482490272374, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=27.5193798449612, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=25.0965250965251, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=172, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=24.4186046511628, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=25.1937984496124, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=224, Percent_Identity=29.0178571428571, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=224, Percent_Identity=29.0178571428571, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=23.8461538461538, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=24.9027237354086, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=25.968992248062, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=237, Percent_Identity=32.4894514767932, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=215, Percent_Identity=27.4418604651163, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=24.5059288537549, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=30.241935483871, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.9236947791165, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=33.8709677419355, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=31.8897637795276, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.8943089430894, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=29.8387096774194, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=31.4516129032258, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357673, Length=196, Percent_Identity=30.1020408163265, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584748, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161076933, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=30.6772908366534, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641232, Length=241, Percent_Identity=32.3651452282158, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24581726, Length=195, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=28.7958115183246, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007236, Length=239, Percent_Identity=29.2887029288703, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=26.8421052631579, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.107 [H]

Molecular weight: Translated: 27016; Mature: 27016

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAHSQQGLVQGRRILVTGAARGLGFSFARTLCESGARVVLADLREELLQQSVATLRAEG
CCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCC
FDASGVAVDVGDPASIQCCAEQAVANLGGLDGLVNNAAVTDSGGRGMDDIEIAKWDQVMN
CCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCCCHHCCHHHEEE
VNVRGTWLMTRACRPALRAGGRGAIVNLASDTAMWGAPNLLAYVASKGAVIAMTHSLARE
ECCCEEEEEHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHH
LGPDNITVNAIAPGLVLVEATQYVPESRHRQYIDQRALQREQMPEDVSGAVLYALSDLAR
CCCCCEEEEEECCCEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FVTGQVLAVNGGFVMR
HHCCEEEEECCCEEEC
>Mature Secondary Structure
MVAHSQQGLVQGRRILVTGAARGLGFSFARTLCESGARVVLADLREELLQQSVATLRAEG
CCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCC
FDASGVAVDVGDPASIQCCAEQAVANLGGLDGLVNNAAVTDSGGRGMDDIEIAKWDQVMN
CCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCCCHHCCHHHEEE
VNVRGTWLMTRACRPALRAGGRGAIVNLASDTAMWGAPNLLAYVASKGAVIAMTHSLARE
ECCCEEEEEHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCEEEEEHHHHHHH
LGPDNITVNAIAPGLVLVEATQYVPESRHRQYIDQRALQREQMPEDVSGAVLYALSDLAR
CCCCCEEEEEECCCEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FVTGQVLAVNGGFVMR
HHCCEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]