Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 91789463

GI number: 91789463

Start: 3813196

End: 3814335

Strand: Direct

Name: asd [H]

Synonym: Bpro_3612

Alternate gene names: 91789463

Gene position: 3813196-3814335 (Clockwise)

Preceding gene: 229558816

Following gene: 91789464

Centisome position: 73.33

GC content: 64.82

Gene sequence:

>1140_bases
ATGAAACTCAAAGGCAATCTCACAGGACTCGTCGGCTGGCGCGGCATGGTCGGCTCGGTGCTGATCGACCGGATGCAGGC
CGAAGGCGACTTCGACCTGATCGAGCCGGTTTTCTTTTCCACCTCCAATGCCGGCGGCAAGGCCCCCGCCCAGGCAAAGA
ACGAAACCACGCTCAAGAATGCCTTTGACATCGAGGCGCTCAAGAAATGCGACGTCATCATCACCGCGCAAGGCGGCGAC
TACACCTCCGAGGTGTTCCCCAAGCTCCGCGCTGCGGGCTGGACGGGCCACTGGATTGACGCGGCCTCCACGCTGCGCAT
GAACGATGACGCCGTGATCATCCTGGATCCGGTCAACCTGCCCGTCATCCAGAACGCGCTAGCCAAGGGCGGCAACAACT
GGATCGGCGGCAACTGCACGGTCAGCTGCATGCTGATGGGCGTGGGTGCACTGTACAAGGCCGGGCTCGTCGAATGGATG
ACCAGCATGACCTACCAGGCCGCTTCCGGCGGCGGCGCGCAGCACATGCGCGAGCTGCTGACCCAGTTCGGCACGCTCAA
CAGCGACGTCAAGGCTCTGCTGGACGACCCGAAATCCGCCATCCTGGAAATCGACCGCCGCGTGCTGGCCAAGCAGCAGT
CGCTGAGTGCCGGCGAAACCGCCAACTTCGGCGTCCCGCTGGGCGGCTCGCTCATCCCCTGGATCGACAAGGACCTGGGC
GACGGCATGAGCAAGGAAGAATGGAAGGGCGGCGCCGAGACCAACAAAATCCTGGGCCAGGGCGCCGCCTTTGGCACGGC
CGAAACGCCGGTCGACGGCTTCTGCGTGCGCATTGGCGCCATGCGCTGCCACAGCCAGGCCCTGACCTTCAAGCTGAAAA
AGGACGTCCCGCTGGCCGACATCGAAGCCATGATCGCCGTCGACAATGACTGGGTCAAAGTCGTGCCCAACACGCGCGAG
GCGTCGATCAAGGACCTGACGCCGGTAGCCGTGACCGGCACCATGCAGATCCCCGTCGGGCGTCTGCGCAAGCTGGCCAT
GGGCCCGGACTACCTGGGCGCCTTCACCGTCGGCGACCAGCTGCTCTGGGGGGCTGCCGAGCCGTTGCGCCGCATGCTGC
GCATCCTGCTGCAGGCTTGA

Upstream 100 bases:

>100_bases
CGACCACCATTAAAGGCTGACAAGCCCGGTTCGTCGTGCCCGCCGGCTCGATGAGCCGGGTCAAAAAGCCGTTTTTTCGT
ACTTTTTGAAGGGCAATTCC

Downstream 100 bases:

>100_bases
ACGCAGGCACGGACGGGCGGCCTGGAGGCACCCCGTCCGTCCGTAACCACTTGTCACAGGTCGTTGTCGTCAGACAACAT
CTGAAACTTGTAAGTTGATG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKLKGNLTGLVGWRGMVGSVLIDRMQAEGDFDLIEPVFFSTSNAGGKAPAQAKNETTLKNAFDIEALKKCDVIITAQGGD
YTSEVFPKLRAAGWTGHWIDAASTLRMNDDAVIILDPVNLPVIQNALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWM
TSMTYQAASGGGAQHMRELLTQFGTLNSDVKALLDDPKSAILEIDRRVLAKQQSLSAGETANFGVPLGGSLIPWIDKDLG
DGMSKEEWKGGAETNKILGQGAAFGTAETPVDGFCVRIGAMRCHSQALTFKLKKDVPLADIEAMIAVDNDWVKVVPNTRE
ASIKDLTPVAVTGTMQIPVGRLRKLAMGPDYLGAFTVGDQLLWGAAEPLRRMLRILLQA

Sequences:

>Translated_379_residues
MKLKGNLTGLVGWRGMVGSVLIDRMQAEGDFDLIEPVFFSTSNAGGKAPAQAKNETTLKNAFDIEALKKCDVIITAQGGD
YTSEVFPKLRAAGWTGHWIDAASTLRMNDDAVIILDPVNLPVIQNALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWM
TSMTYQAASGGGAQHMRELLTQFGTLNSDVKALLDDPKSAILEIDRRVLAKQQSLSAGETANFGVPLGGSLIPWIDKDLG
DGMSKEEWKGGAETNKILGQGAAFGTAETPVDGFCVRIGAMRCHSQALTFKLKKDVPLADIEAMIAVDNDWVKVVPNTRE
ASIKDLTPVAVTGTMQIPVGRLRKLAMGPDYLGAFTVGDQLLWGAAEPLRRMLRILLQA
>Mature_379_residues
MKLKGNLTGLVGWRGMVGSVLIDRMQAEGDFDLIEPVFFSTSNAGGKAPAQAKNETTLKNAFDIEALKKCDVIITAQGGD
YTSEVFPKLRAAGWTGHWIDAASTLRMNDDAVIILDPVNLPVIQNALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWM
TSMTYQAASGGGAQHMRELLTQFGTLNSDVKALLDDPKSAILEIDRRVLAKQQSLSAGETANFGVPLGGSLIPWIDKDLG
DGMSKEEWKGGAETNKILGQGAAFGTAETPVDGFCVRIGAMRCHSQALTFKLKKDVPLADIEAMIAVDNDWVKVVPNTRE
ASIKDLTPVAVTGTMQIPVGRLRKLAMGPDYLGAFTVGDQLLWGAAEPLRRMLRILLQA

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=370, Percent_Identity=62.1621621621622, Blast_Score=465, Evalue=1e-132,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 40566; Mature: 40566

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKGNLTGLVGWRGMVGSVLIDRMQAEGDFDLIEPVFFSTSNAGGKAPAQAKNETTLKN
CCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHCHHHEECCCCCCCCCCCCCCCCHHHH
AFDIEALKKCDVIITAQGGDYTSEVFPKLRAAGWTGHWIDAASTLRMNDDAVIILDPVNL
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEECCCCC
PVIQNALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWMTSMTYQAASGGGAQHMRELL
HHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TQFGTLNSDVKALLDDPKSAILEIDRRVLAKQQSLSAGETANFGVPLGGSLIPWIDKDLG
HHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHC
DGMSKEEWKGGAETNKILGQGAAFGTAETPVDGFCVRIGAMRCHSQALTFKLKKDVPLAD
CCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEEEECCCCCHHC
IEAMIAVDNDWVKVVPNTREASIKDLTPVAVTGTMQIPVGRLRKLAMGPDYLGAFTVGDQ
CEEEEEECCCEEEECCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHCCCCCCEEEECCCH
LLWGAAEPLRRMLRILLQA
HHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLKGNLTGLVGWRGMVGSVLIDRMQAEGDFDLIEPVFFSTSNAGGKAPAQAKNETTLKN
CCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHCHHHEECCCCCCCCCCCCCCCCHHHH
AFDIEALKKCDVIITAQGGDYTSEVFPKLRAAGWTGHWIDAASTLRMNDDAVIILDPVNL
HHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEECCCCC
PVIQNALAKGGNNWIGGNCTVSCMLMGVGALYKAGLVEWMTSMTYQAASGGGAQHMRELL
HHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TQFGTLNSDVKALLDDPKSAILEIDRRVLAKQQSLSAGETANFGVPLGGSLIPWIDKDLG
HHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHC
DGMSKEEWKGGAETNKILGQGAAFGTAETPVDGFCVRIGAMRCHSQALTFKLKKDVPLAD
CCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEEEECCCCCHHC
IEAMIAVDNDWVKVVPNTREASIKDLTPVAVTGTMQIPVGRLRKLAMGPDYLGAFTVGDQ
CEEEEEECCCEEEECCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHCCCCCCEEEECCCH
LLWGAAEPLRRMLRILLQA
HHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]