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The map label for this gene is tag [H]

Identifier: 91789394

GI number: 91789394

Start: 3740974

End: 3741648

Strand: Direct

Name: tag [H]

Synonym: Bpro_3540

Alternate gene names: 91789394

Gene position: 3740974-3741648 (Clockwise)

Preceding gene: 91789391

Following gene: 91789400

Centisome position: 71.94

GC content: 64.74

Gene sequence:

>675_bases
ATGACCTCTGACACCACCGCAGCTGAAAAAACAATGTCGCCCGAGGCGACCGCCGGCCTGTTCACGGACGACGTCCGCAC
CGCCCGCTGCGCCTGGTGCCAGGCCACGCCGCTGTACCGCCACTACCATGACAGCGAGTGGGGATTCCCGGTGGCGGACG
AGCGCCGGCTGTTCGAAAAAATATGCCTTGAAGGCTTTCAGTCGGGCCTGAGCTGGCTGACCATCCTGAACAAGCGCGAA
GCCTTCCGCAGCGCTTTTGCCAATTTCGAGGCCGAACAGGTGGCCGAGTTTGGCGAGAGCGACGTCAAGCGCCTGCTGGG
CGACGCCGGCATCGTGCGGCACGCCGGCAAGATTGCCTCGACCATCAACAACGCCCGGCGCGTGATCGAACTGCGCCGCG
AGTTCGGATCGCTGGGCGCCTTCGTCTGGCGGCTGGAGCCCGAGGCGACCAGCCGGCCCAAGCGCATCACACAGGAAGCC
GTCAGGGCCATGCCGACATCGGCCGCCTCCATCGCGCTGTCCAAAGATCTGAAAAAACGTGGCTGGACCTTTGTGGGGCC
AACCACCCTGTACGCCTTCATGCAGGCCATGGGGCTGGTCAATGACCATCTGGAAGGTTGCGCCAGCCGGCAAAAGGCCC
TGGCCGCCCGTGCAGCGTTCAAGCCACCGCGTTAG

Upstream 100 bases:

>100_bases
CCTTCGCGTCCCTGGTGGCTTGCAAAGCCCTGTCGGCGTACCTGCATGCGGCGCCGAACATCCTTAAAAAACCACCCCAT
CAAGGGGCCTAAAATTTCGT

Downstream 100 bases:

>100_bases
AGCCAGAGAGATACCCTGCGCGGCATCCGCCCGCCTTTCCCCTATCCTGTCCCTACAGCCACCGTGCGCGCTTGAAGCGC
CAGTAGAGCAGCGAGCAGGC

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTSDTTAAEKTMSPEATAGLFTDDVRTARCAWCQATPLYRHYHDSEWGFPVADERRLFEKICLEGFQSGLSWLTILNKRE
AFRSAFANFEAEQVAEFGESDVKRLLGDAGIVRHAGKIASTINNARRVIELRREFGSLGAFVWRLEPEATSRPKRITQEA
VRAMPTSAASIALSKDLKKRGWTFVGPTTLYAFMQAMGLVNDHLEGCASRQKALAARAAFKPPR

Sequences:

>Translated_224_residues
MTSDTTAAEKTMSPEATAGLFTDDVRTARCAWCQATPLYRHYHDSEWGFPVADERRLFEKICLEGFQSGLSWLTILNKRE
AFRSAFANFEAEQVAEFGESDVKRLLGDAGIVRHAGKIASTINNARRVIELRREFGSLGAFVWRLEPEATSRPKRITQEA
VRAMPTSAASIALSKDLKKRGWTFVGPTTLYAFMQAMGLVNDHLEGCASRQKALAARAAFKPPR
>Mature_223_residues
TSDTTAAEKTMSPEATAGLFTDDVRTARCAWCQATPLYRHYHDSEWGFPVADERRLFEKICLEGFQSGLSWLTILNKREA
FRSAFANFEAEQVAEFGESDVKRLLGDAGIVRHAGKIASTINNARRVIELRREFGSLGAFVWRLEPEATSRPKRITQEAV
RAMPTSAASIALSKDLKKRGWTFVGPTTLYAFMQAMGLVNDHLEGCASRQKALAARAAFKPPR

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=181, Percent_Identity=49.7237569060773, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 24947; Mature: 24815

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDTTAAEKTMSPEATAGLFTDDVRTARCAWCQATPLYRHYHDSEWGFPVADERRLFEK
CCCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHH
ICLEGFQSGLSWLTILNKREAFRSAFANFEAEQVAEFGESDVKRLLGDAGIVRHAGKIAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
TINNARRVIELRREFGSLGAFVWRLEPEATSRPKRITQEAVRAMPTSAASIALSKDLKKR
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GWTFVGPTTLYAFMQAMGLVNDHLEGCASRQKALAARAAFKPPR
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSDTTAAEKTMSPEATAGLFTDDVRTARCAWCQATPLYRHYHDSEWGFPVADERRLFEK
CCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHH
ICLEGFQSGLSWLTILNKREAFRSAFANFEAEQVAEFGESDVKRLLGDAGIVRHAGKIAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
TINNARRVIELRREFGSLGAFVWRLEPEATSRPKRITQEAVRAMPTSAASIALSKDLKKR
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GWTFVGPTTLYAFMQAMGLVNDHLEGCASRQKALAARAAFKPPR
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]