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The map label for this gene is rhmD [H]

Identifier: 91789369

GI number: 91789369

Start: 3716348

End: 3717649

Strand: Direct

Name: rhmD [H]

Synonym: Bpro_3515

Alternate gene names: 91789369

Gene position: 3716348-3717649 (Clockwise)

Preceding gene: 91789367

Following gene: 91789370

Centisome position: 71.46

GC content: 65.9

Gene sequence:

>1302_bases
GTGACTACAACCATCACCCGGCTCTCGGTTCGCGACATCCGCTTCCCCACCTCGCGCTCGCTCGATGGCTCGGACGCCAT
GAACGCGGCGCCCGACTATTCGGCCACCTACGTGGTGCTGCACACCGACGCCGCGCAAACGCTGGAAGGCCATGGGCTGA
CCTTCACGATTGGCCGCGGCAATGAAATCTGCGTGGCGGCCGTCAACTCGCTGGCTTCGTTCGTGGTGGGCCGCACGCTC
GAAGACATCACCGCCGACATGGGCGCGTTCTGGCGCAACATCACCAGCGGCGACAGCCAGCTGCGCTGGCTGGGCCCCGA
CAAGGGCGTCATGCACCTCGCGACGGCAGCCATCGTGAACGCCGTCTGGGATCTGTGGGCCAAATCGCAGGGCAAGCCGG
TGTGGAAGCTGCTGACCGACATGAGCCCGGAGCAGCTGGTGCGCTGCCTGGACTTCCGCTTTGTCACCGACGCGCTCACA
CCCGAGGAGGCCGTGGCCCTCCTGCGCCGCCAGGCGCCAACCAAGGCCTTGCGCGAGAAGGAAATGCTGGCGCAGGGCTA
CCCGGGCTACACCACGTCGGCCGGCTGGCTCGGCTATTCCGAAGACAAGGTGCGCCGCCTGGCCCGCGAAGGCGTGGCTG
AAGGCTGGACGCACTTCAAGCAGAAGGTCGGCGGCAACATCGAGGAAGACATCCGCCGCGCCACCATCCTGCGCGAAGAG
ATAGGCTGGGACCGCAAGCTGATGATGGACGCCAACCAGGTGTGGGAAGTGGACGAGTCCATCACCAACATGCGGCGCCT
GGCCGCCTTCGAGCCCTGGTGGATCGAGGAGCCGACCAGCCCGGACGACATCCTCGGCCATGCGGCCATCCGCGCGCGCA
TCGCACCGATTGGCGTGGCGACCGGCGAACACTGCCACAACCGGGTGATGTTCAAGCAGTTGCTGCAGGCCAAGGCCATC
GATTTCTGCCAGGTCGACGCGGCCCGCCTGGGTGGCCTGAACGAAGTCCTGCTGGTGGTGCTGATGGCTGCCAAGTTTGG
CGTGCCGGTGTGTCCGCATGCCGGCGGCGTGGGCCTGTGCGAGTACGTGCAGAACGTGTCGCTGTTCGATTACATCGCAG
TCTCGGGCTCGCTGGAGAACCGTGTGCTGGAGTACGTGGACCACCTGCATGAGCACTTCATCGACCCGGTGGTCATCCGC
AAAGGCCGCTACATGCCGCCGCAACGACCGGGCTACAGCATCGAGATGCATGCCGCGACCCTCAAGGAGTTCGAGTTCCC
GAACGGCTCCGCCTGGGCCTGA

Upstream 100 bases:

>100_bases
AATAGTATCGCAATATACCAAAATAAGATTGGATTGATATCGCCAATCTTTATAAGCTGTGCCATCCATTTCAACCATTT
CAACCACAGGCAAGGCAAAC

Downstream 100 bases:

>100_bases
AGATCCTGAACTTCACGTTCCTTCAAATTATCACGACATCGCTACTAACAAAGAGAGACAAGCATGAAGACATTCACTTC
CCGCATCCTGGCTGGCCTGC

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: RhamD [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTTTITRLSVRDIRFPTSRSLDGSDAMNAAPDYSATYVVLHTDAAQTLEGHGLTFTIGRGNEICVAAVNSLASFVVGRTL
EDITADMGAFWRNITSGDSQLRWLGPDKGVMHLATAAIVNAVWDLWAKSQGKPVWKLLTDMSPEQLVRCLDFRFVTDALT
PEEAVALLRRQAPTKALREKEMLAQGYPGYTTSAGWLGYSEDKVRRLAREGVAEGWTHFKQKVGGNIEEDIRRATILREE
IGWDRKLMMDANQVWEVDESITNMRRLAAFEPWWIEEPTSPDDILGHAAIRARIAPIGVATGEHCHNRVMFKQLLQAKAI
DFCQVDAARLGGLNEVLLVVLMAAKFGVPVCPHAGGVGLCEYVQNVSLFDYIAVSGSLENRVLEYVDHLHEHFIDPVVIR
KGRYMPPQRPGYSIEMHAATLKEFEFPNGSAWA

Sequences:

>Translated_433_residues
MTTTITRLSVRDIRFPTSRSLDGSDAMNAAPDYSATYVVLHTDAAQTLEGHGLTFTIGRGNEICVAAVNSLASFVVGRTL
EDITADMGAFWRNITSGDSQLRWLGPDKGVMHLATAAIVNAVWDLWAKSQGKPVWKLLTDMSPEQLVRCLDFRFVTDALT
PEEAVALLRRQAPTKALREKEMLAQGYPGYTTSAGWLGYSEDKVRRLAREGVAEGWTHFKQKVGGNIEEDIRRATILREE
IGWDRKLMMDANQVWEVDESITNMRRLAAFEPWWIEEPTSPDDILGHAAIRARIAPIGVATGEHCHNRVMFKQLLQAKAI
DFCQVDAARLGGLNEVLLVVLMAAKFGVPVCPHAGGVGLCEYVQNVSLFDYIAVSGSLENRVLEYVDHLHEHFIDPVVIR
KGRYMPPQRPGYSIEMHAATLKEFEFPNGSAWA
>Mature_432_residues
TTTITRLSVRDIRFPTSRSLDGSDAMNAAPDYSATYVVLHTDAAQTLEGHGLTFTIGRGNEICVAAVNSLASFVVGRTLE
DITADMGAFWRNITSGDSQLRWLGPDKGVMHLATAAIVNAVWDLWAKSQGKPVWKLLTDMSPEQLVRCLDFRFVTDALTP
EEAVALLRRQAPTKALREKEMLAQGYPGYTTSAGWLGYSEDKVRRLAREGVAEGWTHFKQKVGGNIEEDIRRATILREEI
GWDRKLMMDANQVWEVDESITNMRRLAAFEPWWIEEPTSPDDILGHAAIRARIAPIGVATGEHCHNRVMFKQLLQAKAID
FCQVDAARLGGLNEVLLVVLMAAKFGVPVCPHAGGVGLCEYVQNVSLFDYIAVSGSLENRVLEYVDHLHEHFIDPVVIRK
GRYMPPQRPGYSIEMHAATLKEFEFPNGSAWA

Specific function: Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR) [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=430, Percent_Identity=59.7674418604651, Blast_Score=561, Evalue=1e-160,
Organism=Homo sapiens, GI42544117, Length=416, Percent_Identity=56.9711538461538, Blast_Score=520, Evalue=1e-148,
Organism=Homo sapiens, GI186972148, Length=337, Percent_Identity=60.2373887240356, Blast_Score=452, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.90 [H]

Molecular weight: Translated: 48182; Mature: 48050

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTITRLSVRDIRFPTSRSLDGSDAMNAAPDYSATYVVLHTDAAQTLEGHGLTFTIGRG
CCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHCCCCEEEEECCC
NEICVAAVNSLASFVVGRTLEDITADMGAFWRNITSGDSQLRWLGPDKGVMHLATAAIVN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
AVWDLWAKSQGKPVWKLLTDMSPEQLVRCLDFRFVTDALTPEEAVALLRRQAPTKALREK
HHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHH
EMLAQGYPGYTTSAGWLGYSEDKVRRLAREGVAEGWTHFKQKVGGNIEEDIRRATILREE
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IGWDRKLMMDANQVWEVDESITNMRRLAAFEPWWIEEPTSPDDILGHAAIRARIAPIGVA
HCCCCEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TGEHCHNRVMFKQLLQAKAIDFCQVDAARLGGLNEVLLVVLMAAKFGVPVCPHAGGVGLC
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EYVQNVSLFDYIAVSGSLENRVLEYVDHLHEHFIDPVVIRKGRYMPPQRPGYSIEMHAAT
HHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCEEEEHHHH
LKEFEFPNGSAWA
HHHHCCCCCCCCC
>Mature Secondary Structure 
TTTITRLSVRDIRFPTSRSLDGSDAMNAAPDYSATYVVLHTDAAQTLEGHGLTFTIGRG
CCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHCCCCEEEEECCC
NEICVAAVNSLASFVVGRTLEDITADMGAFWRNITSGDSQLRWLGPDKGVMHLATAAIVN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
AVWDLWAKSQGKPVWKLLTDMSPEQLVRCLDFRFVTDALTPEEAVALLRRQAPTKALREK
HHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHH
EMLAQGYPGYTTSAGWLGYSEDKVRRLAREGVAEGWTHFKQKVGGNIEEDIRRATILREE
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IGWDRKLMMDANQVWEVDESITNMRRLAAFEPWWIEEPTSPDDILGHAAIRARIAPIGVA
HCCCCEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TGEHCHNRVMFKQLLQAKAIDFCQVDAARLGGLNEVLLVVLMAAKFGVPVCPHAGGVGLC
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EYVQNVSLFDYIAVSGSLENRVLEYVDHLHEHFIDPVVIRKGRYMPPQRPGYSIEMHAAT
HHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCEEEEHHHH
LKEFEFPNGSAWA
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA