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The map label for this gene is tlpA [H]

Identifier: 91789356

GI number: 91789356

Start: 3699856

End: 3700527

Strand: Direct

Name: tlpA [H]

Synonym: Bpro_3502

Alternate gene names: 91789356

Gene position: 3699856-3700527 (Clockwise)

Preceding gene: 91789355

Following gene: 91789357

Centisome position: 71.15

GC content: 65.48

Gene sequence:

>672_bases
GTGAAGGACAGAACAACGGGCCGCCCGGAGGTCGCCGCTATTGACCCCGCCCACGCCGTGCAGGCGAAGACGGCGCGGCC
GCGCGCCGCGGCAGGAAGAAGGGCCTTGCTCGTGCTGCCCATCGTGGCAGGACTGTTTGCCGTTGTGCCGCTGCTTGATC
GAATGCGTAGTCCGCAATCCGCCGGCCTCGACCTCGTCCTTCATGCGCGCCCGAAGGAATTGCCGAATCTGCGGTTCTCC
GATGGGGGAACGCAGACGAGCCTGGCCACCTTCCGAGGCAAGGTCGTGCTGCTCAACGTGTGGGCCACATGGTGCCCGCC
GTGCCTCGAAGAAATGCCGGCCCTGGATCGTTTGCAGGCCGCGCTGGGTGGGCCGCACTTCGAAGTCGTCGCACTCTCAA
TCGATCACGGTGGCCTGCCGGTCGTGCAGGCATTCTTCGATCGCACAAGCATCAAGCACCTGCAGTCATACATGGACACG
TTCGGCGACGCATCTTCGAATCTCGGTGTGGCCGGTGTTCCGCTGACGCTGCTCATCGACCGGGAGGGCCGCGAGATCGG
CCGCAAACTCGGTCCGGCGGCGTGGGACGACCCGCGGATGGTCCAACTGATACACAGCCACATGGCGCCTGGTGCGGCGC
CATCGCAACCCGAAGGTAGACCATGGCCCTGA

Upstream 100 bases:

>100_bases
GCAAGCCGGTCATCGTCGGCAGCGGCATGCAGGGGGACCGGGCCGCGGTCGTCTTCTCGCGCCCCGAGGAGATATCGATG
TTCATTCGAAGGGAGTGCCC

Downstream 100 bases:

>100_bases
GAGCATTTCCTGTCGTCGCGCTCGTGCTACTCGTGGTCGCCTGCGGCGAGCGCACGGGCGGTTCAACGTCGCCGGTCAAG
TCAGCCGACATATAACAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKDRTTGRPEVAAIDPAHAVQAKTARPRAAAGRRALLVLPIVAGLFAVVPLLDRMRSPQSAGLDLVLHARPKELPNLRFS
DGGTQTSLATFRGKVVLLNVWATWCPPCLEEMPALDRLQAALGGPHFEVVALSIDHGGLPVVQAFFDRTSIKHLQSYMDT
FGDASSNLGVAGVPLTLLIDREGREIGRKLGPAAWDDPRMVQLIHSHMAPGAAPSQPEGRPWP

Sequences:

>Translated_223_residues
MKDRTTGRPEVAAIDPAHAVQAKTARPRAAAGRRALLVLPIVAGLFAVVPLLDRMRSPQSAGLDLVLHARPKELPNLRFS
DGGTQTSLATFRGKVVLLNVWATWCPPCLEEMPALDRLQAALGGPHFEVVALSIDHGGLPVVQAFFDRTSIKHLQSYMDT
FGDASSNLGVAGVPLTLLIDREGREIGRKLGPAAWDDPRMVQLIHSHMAPGAAPSQPEGRPWP
>Mature_223_residues
MKDRTTGRPEVAAIDPAHAVQAKTARPRAAAGRRALLVLPIVAGLFAVVPLLDRMRSPQSAGLDLVLHARPKELPNLRFS
DGGTQTSLATFRGKVVLLNVWATWCPPCLEEMPALDRLQAALGGPHFEVVALSIDHGGLPVVQAFFDRTSIKHLQSYMDT
FGDASSNLGVAGVPLTLLIDREGREIGRKLGPAAWDDPRMVQLIHSHMAPGAAPSQPEGRPWP

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 24002; Mature: 24002

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRTTGRPEVAAIDPAHAVQAKTARPRAAAGRRALLVLPIVAGLFAVVPLLDRMRSPQS
CCCCCCCCCCEEEECCHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AGLDLVLHARPKELPNLRFSDGGTQTSLATFRGKVVLLNVWATWCPPCLEEMPALDRLQA
CCCEEEEECCCCCCCCCEECCCCCCHHHHHHCCCEEEEEEHHHHCCHHHHHCCHHHHHHH
ALGGPHFEVVALSIDHGGLPVVQAFFDRTSIKHLQSYMDTFGDASSNLGVAGVPLTLLID
HHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
REGREIGRKLGPAAWDDPRMVQLIHSHMAPGAAPSQPEGRPWP
CCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKDRTTGRPEVAAIDPAHAVQAKTARPRAAAGRRALLVLPIVAGLFAVVPLLDRMRSPQS
CCCCCCCCCCEEEECCHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AGLDLVLHARPKELPNLRFSDGGTQTSLATFRGKVVLLNVWATWCPPCLEEMPALDRLQA
CCCEEEEECCCCCCCCCEECCCCCCHHHHHHCCCEEEEEEHHHHCCHHHHHCCHHHHHHH
ALGGPHFEVVALSIDHGGLPVVQAFFDRTSIKHLQSYMDTFGDASSNLGVAGVPLTLLID
HHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
REGREIGRKLGPAAWDDPRMVQLIHSHMAPGAAPSQPEGRPWP
CCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]