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The map label for this gene is acrE [H]

Identifier: 91789300

GI number: 91789300

Start: 3647410

End: 3648519

Strand: Direct

Name: acrE [H]

Synonym: Bpro_3445

Alternate gene names: 91789300

Gene position: 3647410-3648519 (Clockwise)

Preceding gene: 91789299

Following gene: 91789301

Centisome position: 70.14

GC content: 63.51

Gene sequence:

>1110_bases
ATGCTCAGGCGTTACTTCGCTACATCTATAGTCATTTGTGCATTGCCTTTGGTGTTGGCCGCTTGCGGCGACAAGGCGCA
ATCTGATCCACGTACCGAGGCGCCGCTGGTACGTGTGGCCACCATTCAGGGCTCGGTCGCTGCGTCTCGCGCGTTCACCG
GGACCGTAGCCGCTCGGGTACAAAGCGATCTGGGCTTTCGGGTCTCGGGCAAGGTGCTGGAACGCCTTGTCGATGCGGGG
CAAGCCGTTAAGCGCGGGCAAGCGCTCATGCGCATCGATCCCATCGACCTGAAGCTCGCCGCTAATGCGCAACTGGAAGC
AGTGGCCGCCGCCCGGGCGCGGGCGCAGCAAACGGCGCAGGACGAAGCCCGCTACCAGGACCTGCGCGGAACCGGTGCCA
TTTCAGCCTCAGCCTATGACCAGGTCAAGGCTGCAGCAGATGCGGCCAAAGCCCAGCTCAACGCAACCGAAGCCCAGGCC
GAAGTCGCTCGAAACGCGAGCCGCTATACGGAACTGGTGGCAGATGGCGATGGCATCGTCATGGAAACGCTGGTGGAACC
CGGCCAGGTCGTCAACGCGGGACAGGTCGTGGTGCGTCTGGCCCATGCCGGCCGCCGTGAAGCCGTCATTCAACTACCGG
AAACCTTGCGCCCTGCGGTCGGTTCAACCGGGCTGGCCACGCTCTTTGGCCAGGAAGGCGTAGCCGTTCCGACCAAACTC
AGGCAGCTCTCGAACGCCGCGGACCGGCTGACGCGCACTTTCGAAGCGCGCTATGTGCTGGATGGCGAGCTATCCAACGC
CCCATTGGGCAGCACAGTCACCGTTCAAATCCCGGACGCAAATTCCACTACGCAAGACGGCTTTTCGGTACCCATTGCTT
CCTTGTCCGACGCGGGCAAAGGGCCGGGGGTCTGGGTTATCCAGGGCGAGCCAGCCAAGGTTTCATGGCGGCCAGTAAAG
GTCCAGCGCCTGGGCGACGACAGTGCTTACATTGCGGGTCAGCTCAAGCAGGGTGACCGGATCGTCGCACTCGGCACGCA
TCTGCTGCGCGAAGGCGAGCAAATCCGCGTGGCGGCTCAAGCGCCCGTAACTGCAAGCGCGCGGCCATGA

Upstream 100 bases:

>100_bases
GTGCTTCGCAGCCTGTCACCATAAATAAAACTGTGACTATTGACTAATTTGGTCACAAGTACCATAATGAAAGTCCAATC
ATTTCGTCAATGGGACTTTC

Downstream 100 bases:

>100_bases
GCGAAGGCCGTTTCAACCTGTCGGCGCTCGCCGTGCGCGAGCGCTCCGTCACCCTGTTCCTGATCTGCCTGATCTCGTTG
GCAGGGCTCATTGCGTTCCT

Product: secretion protein HlyD

Products: NA

Alternate protein names: Protein envC [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLRRYFATSIVICALPLVLAACGDKAQSDPRTEAPLVRVATIQGSVAASRAFTGTVAARVQSDLGFRVSGKVLERLVDAG
QAVKRGQALMRIDPIDLKLAANAQLEAVAAARARAQQTAQDEARYQDLRGTGAISASAYDQVKAAADAAKAQLNATEAQA
EVARNASRYTELVADGDGIVMETLVEPGQVVNAGQVVVRLAHAGRREAVIQLPETLRPAVGSTGLATLFGQEGVAVPTKL
RQLSNAADRLTRTFEARYVLDGELSNAPLGSTVTVQIPDANSTTQDGFSVPIASLSDAGKGPGVWVIQGEPAKVSWRPVK
VQRLGDDSAYIAGQLKQGDRIVALGTHLLREGEQIRVAAQAPVTASARP

Sequences:

>Translated_369_residues
MLRRYFATSIVICALPLVLAACGDKAQSDPRTEAPLVRVATIQGSVAASRAFTGTVAARVQSDLGFRVSGKVLERLVDAG
QAVKRGQALMRIDPIDLKLAANAQLEAVAAARARAQQTAQDEARYQDLRGTGAISASAYDQVKAAADAAKAQLNATEAQA
EVARNASRYTELVADGDGIVMETLVEPGQVVNAGQVVVRLAHAGRREAVIQLPETLRPAVGSTGLATLFGQEGVAVPTKL
RQLSNAADRLTRTFEARYVLDGELSNAPLGSTVTVQIPDANSTTQDGFSVPIASLSDAGKGPGVWVIQGEPAKVSWRPVK
VQRLGDDSAYIAGQLKQGDRIVALGTHLLREGEQIRVAAQAPVTASARP
>Mature_369_residues
MLRRYFATSIVICALPLVLAACGDKAQSDPRTEAPLVRVATIQGSVAASRAFTGTVAARVQSDLGFRVSGKVLERLVDAG
QAVKRGQALMRIDPIDLKLAANAQLEAVAAARARAQQTAQDEARYQDLRGTGAISASAYDQVKAAADAAKAQLNATEAQA
EVARNASRYTELVADGDGIVMETLVEPGQVVNAGQVVVRLAHAGRREAVIQLPETLRPAVGSTGLATLFGQEGVAVPTKL
RQLSNAADRLTRTFEARYVLDGELSNAPLGSTVTVQIPDANSTTQDGFSVPIASLSDAGKGPGVWVIQGEPAKVSWRPVK
VQRLGDDSAYIAGQLKQGDRIVALGTHLLREGEQIRVAAQAPVTASARP

Specific function: May affect specific membrane functions, such as septum formation during cell division, and cell membrane permeability [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=383, Percent_Identity=24.8041775456919, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38715; Mature: 38715

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRYFATSIVICALPLVLAACGDKAQSDPRTEAPLVRVATIQGSVAASRAFTGTVAARV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
QSDLGFRVSGKVLERLVDAGQAVKRGQALMRIDPIDLKLAANAQLEAVAAARARAQQTAQ
HHCCCCEECHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHH
DEARYQDLRGTGAISASAYDQVKAAADAAKAQLNATEAQAEVARNASRYTELVADGDGIV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEE
METLVEPGQVVNAGQVVVRLAHAGRREAVIQLPETLRPAVGSTGLATLFGQEGVAVPTKL
EHHHCCCCCEECHHHHHHHHHHCCCCHHEEECCHHHHHHCCCCCHHHHHCCCCCCCHHHH
RQLSNAADRLTRTFEARYVLDGELSNAPLGSTVTVQIPDANSTTQDGFSVPIASLSDAGK
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCC
GPGVWVIQGEPAKVSWRPVKVQRLGDDSAYIAGQLKQGDRIVALGTHLLREGEQIRVAAQ
CCCEEEEECCCCEEEEEEEEEEECCCCCCEEEEECCCCCEEEEECHHHHCCCCEEEEEEE
APVTASARP
CCCCCCCCC
>Mature Secondary Structure
MLRRYFATSIVICALPLVLAACGDKAQSDPRTEAPLVRVATIQGSVAASRAFTGTVAARV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
QSDLGFRVSGKVLERLVDAGQAVKRGQALMRIDPIDLKLAANAQLEAVAAARARAQQTAQ
HHCCCCEECHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHH
DEARYQDLRGTGAISASAYDQVKAAADAAKAQLNATEAQAEVARNASRYTELVADGDGIV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEE
METLVEPGQVVNAGQVVVRLAHAGRREAVIQLPETLRPAVGSTGLATLFGQEGVAVPTKL
EHHHCCCCCEECHHHHHHHHHHCCCCHHEEECCHHHHHHCCCCCHHHHHCCCCCCCHHHH
RQLSNAADRLTRTFEARYVLDGELSNAPLGSTVTVQIPDANSTTQDGFSVPIASLSDAGK
HHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCC
GPGVWVIQGEPAKVSWRPVKVQRLGDDSAYIAGQLKQGDRIVALGTHLLREGEQIRVAAQ
CCCEEEEECCCCEEEEEEEEEEECCCCCCEEEEECCCCCEEEEECHHHHCCCCEEEEEEE
APVTASARP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1720861; 9278503 [H]