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The map label for this gene is gntR [H]

Identifier: 91789273

GI number: 91789273

Start: 3615199

End: 3616242

Strand: Direct

Name: gntR [H]

Synonym: Bpro_3418

Alternate gene names: 91789273

Gene position: 3615199-3616242 (Clockwise)

Preceding gene: 91789270

Following gene: 91789274

Centisome position: 69.52

GC content: 68.87

Gene sequence:

>1044_bases
ATGAACCACGAGGACACGCCAACGGACACCCAGACGCGACGAACCCGCCGGGGCAGCGGCGCCGTCACCCTGCATGACGT
GGCCAAGCTGGCCGGCGTGGCGCCCATCACCGCGTCACGCGCCCTGAACACCCCCACCCAGGTTTCAGCTGAGGTGCTGA
AGAAAGTCACCGACGCGGTGCAGCGTACCGGCTACGTGCCCAACCGGCTCGCCGGGGGCCTGGCGTCATCGCGCAGCCGC
CTGGTGGCGGCGGTCGTGCCCACCCTCAACGGCCCGGTGTTCCTGGAAACCGTGCAAGCCCTGACGGATGCCCTGGCCGA
ACAGGGCTACCAGTTGATGCTGGGCCAGAGCGGCTATGTGGATTCACGCGAGGATGCCCTGCTGGAAGCCATCATTGGCC
GCCGGCCGGACGGCATTGTGCTGACCGGCATCATGCATTCCCCCGAGGGACGCAAGCGCCTGCTGGCGGCCGGCATACCG
GTTGTCGAAACCTGGGACCTCACGCCCACCCCGCTGGACATGCTGGTCGGCTTTTCCCATGTGGATGTCGGGCGCGCGGT
GGTCGATTTTCTCTATGCCAGGGGACGACGCCGCCTGGCGATCGTGGCGGGCGACGACGAGCGTTCGACACGCCGCCACC
AGGCTTTCCAGGCCGCGGCGCGGGCCGCGGGCCTGCCCGAAGTCCGGATGGTGACCGTGCCCGCGCCGACCACCGCGAAA
AGCGGCCGCAGCGCGCTGGCCGAACTGATGCGGGACGCGGGTGATATCGATGCCGTGTTTTGCAGTTCGGACCTGCTGGC
GCTGGGCGTTCTGATGCAAGCCCAGGCCAGCGGCATTGCGGTGCCCGGGCAACTGGCCATCGTGGGCTTCGGCGACCTGG
AGTTTGCCGCCGACCTGAACCCCGCGCTGACAACAGTGCGCATCGATGGCACGGCCATCGGCCGGCAGGCCGCCCGGTTC
ATCGTGGAGCGTGCGGAAGGCCGGCCGGTGGAGCCACGGGTCGTCGACATCGGCTTCACGATTGTCGAACGGGGCAGCAC
CTGA

Upstream 100 bases:

>100_bases
TCTGGCAAATGAAACACCCGCAACAATTCCCGGCAGGCCTGGCGCCATGCATCCGCAGTGTTCGCATGACTGGTAGCGCT
ATCGTCGATAGAATCGGCCC

Downstream 100 bases:

>100_bases
TGCACATCGGGAGTGACCCGGCAATTTGTCTCCGCACCACCCCGGGCAGGCAGCCGGCATAGGCCGCGCTGCGGGCAGGC
CGGAATCCGCAGAACAGAGG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNHEDTPTDTQTRRTRRGSGAVTLHDVAKLAGVAPITASRALNTPTQVSAEVLKKVTDAVQRTGYVPNRLAGGLASSRSR
LVAAVVPTLNGPVFLETVQALTDALAEQGYQLMLGQSGYVDSREDALLEAIIGRRPDGIVLTGIMHSPEGRKRLLAAGIP
VVETWDLTPTPLDMLVGFSHVDVGRAVVDFLYARGRRRLAIVAGDDERSTRRHQAFQAAARAAGLPEVRMVTVPAPTTAK
SGRSALAELMRDAGDIDAVFCSSDLLALGVLMQAQASGIAVPGQLAIVGFGDLEFAADLNPALTTVRIDGTAIGRQAARF
IVERAEGRPVEPRVVDIGFTIVERGST

Sequences:

>Translated_347_residues
MNHEDTPTDTQTRRTRRGSGAVTLHDVAKLAGVAPITASRALNTPTQVSAEVLKKVTDAVQRTGYVPNRLAGGLASSRSR
LVAAVVPTLNGPVFLETVQALTDALAEQGYQLMLGQSGYVDSREDALLEAIIGRRPDGIVLTGIMHSPEGRKRLLAAGIP
VVETWDLTPTPLDMLVGFSHVDVGRAVVDFLYARGRRRLAIVAGDDERSTRRHQAFQAAARAAGLPEVRMVTVPAPTTAK
SGRSALAELMRDAGDIDAVFCSSDLLALGVLMQAQASGIAVPGQLAIVGFGDLEFAADLNPALTTVRIDGTAIGRQAARF
IVERAEGRPVEPRVVDIGFTIVERGST
>Mature_347_residues
MNHEDTPTDTQTRRTRRGSGAVTLHDVAKLAGVAPITASRALNTPTQVSAEVLKKVTDAVQRTGYVPNRLAGGLASSRSR
LVAAVVPTLNGPVFLETVQALTDALAEQGYQLMLGQSGYVDSREDALLEAIIGRRPDGIVLTGIMHSPEGRKRLLAAGIP
VVETWDLTPTPLDMLVGFSHVDVGRAVVDFLYARGRRRLAIVAGDDERSTRRHQAFQAAARAAGLPEVRMVTVPAPTTAK
SGRSALAELMRDAGDIDAVFCSSDLLALGVLMQAQASGIAVPGQLAIVGFGDLEFAADLNPALTTVRIDGTAIGRQAARF
IVERAEGRPVEPRVVDIGFTIVERGST

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1790715, Length=333, Percent_Identity=30.6306306306306, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=28.6549707602339, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=26.3636363636364, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787948, Length=344, Percent_Identity=25.8720930232558, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788474, Length=331, Percent_Identity=27.4924471299094, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789202, Length=329, Percent_Identity=27.0516717325228, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786540, Length=337, Percent_Identity=25.2225519287834, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=24.4582043343653, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789068, Length=301, Percent_Identity=25.9136212624585, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790689, Length=332, Percent_Identity=26.8072289156627, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787906, Length=256, Percent_Identity=26.171875, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786268, Length=154, Percent_Identity=27.9220779220779, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789456, Length=345, Percent_Identity=24.9275362318841, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36756; Mature: 36756

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHEDTPTDTQTRRTRRGSGAVTLHDVAKLAGVAPITASRALNTPTQVSAEVLKKVTDAV
CCCCCCCCCHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
QRTGYVPNRLAGGLASSRSRLVAAVVPTLNGPVFLETVQALTDALAEQGYQLMLGQSGYV
HHCCCCCHHHHCCHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCC
DSREDALLEAIIGRRPDGIVLTGIMHSPEGRKRLLAAGIPVVETWDLTPTPLDMLVGFSH
CCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHCCCCEEEECCCCCCCHHHHHCCCH
VDVGRAVVDFLYARGRRRLAIVAGDDERSTRRHQAFQAAARAAGLPEVRMVTVPAPTTAK
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
SGRSALAELMRDAGDIDAVFCSSDLLALGVLMQAQASGIAVPGQLAIVGFGDLEFAADLN
CHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEECCCC
PALTTVRIDGTAIGRQAARFIVERAEGRPVEPRVVDIGFTIVERGST
CCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCC
>Mature Secondary Structure
MNHEDTPTDTQTRRTRRGSGAVTLHDVAKLAGVAPITASRALNTPTQVSAEVLKKVTDAV
CCCCCCCCCHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
QRTGYVPNRLAGGLASSRSRLVAAVVPTLNGPVFLETVQALTDALAEQGYQLMLGQSGYV
HHCCCCCHHHHCCHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCC
DSREDALLEAIIGRRPDGIVLTGIMHSPEGRKRLLAAGIPVVETWDLTPTPLDMLVGFSH
CCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHCCCCEEEECCCCCCCHHHHHCCCH
VDVGRAVVDFLYARGRRRLAIVAGDDERSTRRHQAFQAAARAAGLPEVRMVTVPAPTTAK
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
SGRSALAELMRDAGDIDAVFCSSDLLALGVLMQAQASGIAVPGQLAIVGFGDLEFAADLN
CHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEECCCC
PALTTVRIDGTAIGRQAARFIVERAEGRPVEPRVVDIGFTIVERGST
CCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]