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The map label for this gene is dapA [C]

Identifier: 91789274

GI number: 91789274

Start: 3616435

End: 3617421

Strand: Direct

Name: dapA [C]

Synonym: Bpro_3419

Alternate gene names: 91789274

Gene position: 3616435-3617421 (Clockwise)

Preceding gene: 91789273

Following gene: 91789275

Centisome position: 69.54

GC content: 66.06

Gene sequence:

>987_bases
ATGGTAGCGCTACCTTTACCCGGAAACGCTGATTTGTTCACCCAACCACCTCCTTCTTCACGACCCCTTCGCATGACCAC
CCCGCAAGACCTCAAGAAAATCATCTCCTACGGCCTGCTCTCGTTCCCCCTGACCGACTTCGACAGCCAGCTGCGTTTTG
CCGCAAAGCCTTTCGCCGAGCGACTGGAGTGGCTCATGCCCTACGGCGCCACGGCGCTGTTTGCGGCCGGCGGCACGGGC
GAGTTTTTCTCGCTGGAGCCGCAGGAGTACAGCGAGGTCGTGCACACCGCGATCCAGACCTGCCAGGGCCGCATGCCCAT
CATTGCCGGCGCGGGCGGCGGCACCACGCTGGCAATTCGCTATGCGCAGGAGGCCGAGCGGCTGGGCGCCCAGGGCATCC
TGCTGCTGCCCCACTACCTGACCGAAGCGACGCAGGAAGGCCTGGTGGCGCACATTGAGGCAGTGTGCAGGAGCGTCAGG
TTCGGCGTCATCGTCTACAACCGCGCCGCCTGCCGCCTGACGCCGGAGTCCCTGCTGATACTGGCCGACCGCTGCCCCAA
CCTGATCGGCTTCAAGGACGGCATTGGCGACATCGAGTCCTTCGTCACCATCCGCCGCAAGCTGGGCGACCGCTTCGCCT
ACCTTGGCGGGCTGCCCACCGCGGAAGTCTTTGCCGGCGCCTACCAGGCGATGGGCTGCCCGGTTTATTCGTCGGCCGTG
TTCAACTTCATCCCCCGCACGGCCATGGAGTTCTACAACGCCCACCACGCCGGCGACACCGCCACCACCAACCGCCTGCT
GGACGGGTTCTTCCTGCCCTACATTGCGCTGCGCAACCAGGGCCAGGGCTACGGCGTGAGCATCGTCAAGGCCGGCGCCA
CGCTGGTGGGCCACACCGCCGGACCGGTGCGCCCGCCGCTGTCGGACCTCAAGCCCGCCGAGATGGAACAGCTCGGCCAG
TTGATCGCCAAACTCGGCGCCCAGTAA

Upstream 100 bases:

>100_bases
AACAGAGGCCGAAAAGACCGGAAAAGTCAGGGATACGTAATATCCCGCATCAATTTCTGCTTGCTTTCCTCAAAAGGTAG
CGCTACCATTCAAGGCTTCA

Downstream 100 bases:

>100_bases
AGCGCCACCATCCCAGGAGACATCTTCATGAGAAAACTGTTATCTGCCCTAATGATGGGTCTGCTAGCTACGGCAAGCGT
GCATGCTCAAACCTGGCCCA

Product: 5-dehydro-4-deoxyglucarate dehydratase

Products: NA

Alternate protein names: 5-keto-4-deoxy-glucarate dehydratase; KDGDH [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MVALPLPGNADLFTQPPPSSRPLRMTTPQDLKKIISYGLLSFPLTDFDSQLRFAAKPFAERLEWLMPYGATALFAAGGTG
EFFSLEPQEYSEVVHTAIQTCQGRMPIIAGAGGGTTLAIRYAQEAERLGAQGILLLPHYLTEATQEGLVAHIEAVCRSVR
FGVIVYNRAACRLTPESLLILADRCPNLIGFKDGIGDIESFVTIRRKLGDRFAYLGGLPTAEVFAGAYQAMGCPVYSSAV
FNFIPRTAMEFYNAHHAGDTATTNRLLDGFFLPYIALRNQGQGYGVSIVKAGATLVGHTAGPVRPPLSDLKPAEMEQLGQ
LIAKLGAQ

Sequences:

>Translated_328_residues
MVALPLPGNADLFTQPPPSSRPLRMTTPQDLKKIISYGLLSFPLTDFDSQLRFAAKPFAERLEWLMPYGATALFAAGGTG
EFFSLEPQEYSEVVHTAIQTCQGRMPIIAGAGGGTTLAIRYAQEAERLGAQGILLLPHYLTEATQEGLVAHIEAVCRSVR
FGVIVYNRAACRLTPESLLILADRCPNLIGFKDGIGDIESFVTIRRKLGDRFAYLGGLPTAEVFAGAYQAMGCPVYSSAV
FNFIPRTAMEFYNAHHAGDTATTNRLLDGFFLPYIALRNQGQGYGVSIVKAGATLVGHTAGPVRPPLSDLKPAEMEQLGQ
LIAKLGAQ
>Mature_328_residues
MVALPLPGNADLFTQPPPSSRPLRMTTPQDLKKIISYGLLSFPLTDFDSQLRFAAKPFAERLEWLMPYGATALFAAGGTG
EFFSLEPQEYSEVVHTAIQTCQGRMPIIAGAGGGTTLAIRYAQEAERLGAQGILLLPHYLTEATQEGLVAHIEAVCRSVR
FGVIVYNRAACRLTPESLLILADRCPNLIGFKDGIGDIESFVTIRRKLGDRFAYLGGLPTAEVFAGAYQAMGCPVYSSAV
FNFIPRTAMEFYNAHHAGDTATTNRLLDGFFLPYIALRNQGQGYGVSIVKAGATLVGHTAGPVRPPLSDLKPAEMEQLGQ
LIAKLGAQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Escherichia coli, GI1788823, Length=178, Percent_Identity=29.7752808988764, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082415, Length=218, Percent_Identity=27.5229357798165, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786463, Length=207, Percent_Identity=28.0193236714976, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017655
- InterPro:   IPR002220 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.41 [H]

Molecular weight: Translated: 35397; Mature: 35397

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALPLPGNADLFTQPPPSSRPLRMTTPQDLKKIISYGLLSFPLTDFDSQLRFAAKPFAE
CEEECCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RLEWLMPYGATALFAAGGTGEFFSLEPQEYSEVVHTAIQTCQGRMPIIAGAGGGTTLAIR
HHHHHCCCCCCEEEECCCCCCCEECCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEE
YAQEAERLGAQGILLLPHYLTEATQEGLVAHIEAVCRSVRFGVIVYNRAACRLTPESLLI
EHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECHHHHEE
LADRCPNLIGFKDGIGDIESFVTIRRKLGDRFAYLGGLPTAEVFAGAYQAMGCPVYSSAV
EHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
FNFIPRTAMEFYNAHHAGDTATTNRLLDGFFLPYIALRNQGQGYGVSIVKAGATLVGHTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCC
GPVRPPLSDLKPAEMEQLGQLIAKLGAQ
CCCCCCHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVALPLPGNADLFTQPPPSSRPLRMTTPQDLKKIISYGLLSFPLTDFDSQLRFAAKPFAE
CEEECCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RLEWLMPYGATALFAAGGTGEFFSLEPQEYSEVVHTAIQTCQGRMPIIAGAGGGTTLAIR
HHHHHCCCCCCEEEECCCCCCCEECCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEE
YAQEAERLGAQGILLLPHYLTEATQEGLVAHIEAVCRSVRFGVIVYNRAACRLTPESLLI
EHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEECHHHHEE
LADRCPNLIGFKDGIGDIESFVTIRRKLGDRFAYLGGLPTAEVFAGAYQAMGCPVYSSAV
EHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
FNFIPRTAMEFYNAHHAGDTATTNRLLDGFFLPYIALRNQGQGYGVSIVKAGATLVGHTA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCC
GPVRPPLSDLKPAEMEQLGQLIAKLGAQ
CCCCCCHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA