Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 91789200

GI number: 91789200

Start: 3541059

End: 3541892

Strand: Reverse

Name: uppP

Synonym: Bpro_3344

Alternate gene names: 91789200

Gene position: 3541892-3541059 (Counterclockwise)

Preceding gene: 91789202

Following gene: 91789199

Centisome position: 68.11

GC content: 58.87

Gene sequence:

>834_bases
GTGGACATTGCACTGTTGATCAAAGCCGCCATCATGGGGGTCGTTGAAGGTTTAACCGAGTTTCTTCCCATTTCTTCCAC
TGGACACCTCATCCTTGCGGGTGCATTGCTGGGTTTTGATGACGACAAGGCCAAGGTGTTTGACATCGCCATACAGACCG
GCGCCATCTTTGCCGTCATTTTGGTGTACTGGCAAAAAATCCGCGACACGCTGGTGGCGCTTCCGACTGAAAAGCAGGCG
CAGCAATTTGCGCTGAACGTGCTGGTGGCTTTTGTGCCGGCCGTGGTGTTGGGCCTGCTGTTTGGCAAGGCCATTCAGGC
ACATCTGTTTACGCCAGTGGTGGTGGCCAGCACCTTTGTCATTGGCGGCTTCATCATCCTGTGGGCGGAAAAGCGCCAGG
AGCGCAATCCGGCCGTCGCGCGCATTCATGAAGTCGAGGCCATGACGGTGATGGATGCGCTCAAGGTCGGCCTGGTGCAG
TGCCTGGCCATGATCCCGGGCACCAGCCGCAGCGGCGCCACCATCATTGGCGGCATGTTGCTGGGGCTGTCGCGCAAGGC
CGCTACCGACTTTTCTTTTTACCTCGCCATTCCCACGCTGATTGGCGCGGGCGTCTACAGCCTGTACAAGGAGCGTGCGC
TGCTGTCCGTGGCTGATGTGCCCTTGTTCATGGTGGGGCTGGTGTTTTCGTTTGTCAGCGCGTGGCTGTGCATTCGCTGG
CTGTTGCGCTACATCTCCAGCCACAGCTTTATACCTTTTGCCTGGTACCGCATTGCCTTTGGCGTGGTCGTGCTGGCCAC
CGCGTGGAGCGGTGTGGTGACCTGGACCCCCTGA

Upstream 100 bases:

>100_bases
GGGCATGATGTGTTCAGCTTAACCGCAATGGCCCTCAGGAAAGCTTAAGCCCTCGCTCAGGATGGCGGGCGATAATCAAG
CCCAAATTTCAGGAGCCTGA

Downstream 100 bases:

>100_bases
GCATTCCACACCGCTCCCCTCGTTTTTTTGACGGGCCCGCCAGCAATGGCAGGGCCCGTTTTTCTTTGGGGCAGGGATTG
GGGTTGGGATTGGGGATCTC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MDIALLIKAAIMGVVEGLTEFLPISSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVILVYWQKIRDTLVALPTEKQA
QQFALNVLVAFVPAVVLGLLFGKAIQAHLFTPVVVASTFVIGGFIILWAEKRQERNPAVARIHEVEAMTVMDALKVGLVQ
CLAMIPGTSRSGATIIGGMLLGLSRKAATDFSFYLAIPTLIGAGVYSLYKERALLSVADVPLFMVGLVFSFVSAWLCIRW
LLRYISSHSFIPFAWYRIAFGVVVLATAWSGVVTWTP

Sequences:

>Translated_277_residues
MDIALLIKAAIMGVVEGLTEFLPISSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVILVYWQKIRDTLVALPTEKQA
QQFALNVLVAFVPAVVLGLLFGKAIQAHLFTPVVVASTFVIGGFIILWAEKRQERNPAVARIHEVEAMTVMDALKVGLVQ
CLAMIPGTSRSGATIIGGMLLGLSRKAATDFSFYLAIPTLIGAGVYSLYKERALLSVADVPLFMVGLVFSFVSAWLCIRW
LLRYISSHSFIPFAWYRIAFGVVVLATAWSGVVTWTP
>Mature_277_residues
MDIALLIKAAIMGVVEGLTEFLPISSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVILVYWQKIRDTLVALPTEKQA
QQFALNVLVAFVPAVVLGLLFGKAIQAHLFTPVVVASTFVIGGFIILWAEKRQERNPAVARIHEVEAMTVMDALKVGLVQ
CLAMIPGTSRSGATIIGGMLLGLSRKAATDFSFYLAIPTLIGAGVYSLYKERALLSVADVPLFMVGLVFSFVSAWLCIRW
LLRYISSHSFIPFAWYRIAFGVVVLATAWSGVVTWTP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=263, Percent_Identity=44.8669201520913, Blast_Score=219, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_POLSJ (Q127N8)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550152.1
- STRING:   Q127N8
- GeneID:   4013997
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3344
- NMPDR:   fig|296591.1.peg.1284
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- PhylomeDB:   Q127N8
- ProtClustDB:   PRK00281
- BioCyc:   PSP296591:BPRO_3344-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30018; Mature: 30018

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xaea9344)-; HASH(0x16b34b50)-; HASH(0x16b34d3c)-; HASH(0x16b34be0)-; HASH(0x16b354c0)-; HASH(0x15c8d7b4)-; HASH(0xaf2dd44)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIALLIKAAIMGVVEGLTEFLPISSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCEEEEHHHHHHHHHHH
LVYWQKIRDTLVALPTEKQAQQFALNVLVAFVPAVVLGLLFGKAIQAHLFTPVVVASTFV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGFIILWAEKRQERNPAVARIHEVEAMTVMDALKVGLVQCLAMIPGTSRSGATIIGGML
HHHHHEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LGLSRKAATDFSFYLAIPTLIGAGVYSLYKERALLSVADVPLFMVGLVFSFVSAWLCIRW
HHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRYISSHSFIPFAWYRIAFGVVVLATAWSGVVTWTP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECH
>Mature Secondary Structure
MDIALLIKAAIMGVVEGLTEFLPISSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCEEEEHHHHHHHHHHH
LVYWQKIRDTLVALPTEKQAQQFALNVLVAFVPAVVLGLLFGKAIQAHLFTPVVVASTFV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGFIILWAEKRQERNPAVARIHEVEAMTVMDALKVGLVQCLAMIPGTSRSGATIIGGML
HHHHHEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LGLSRKAATDFSFYLAIPTLIGAGVYSLYKERALLSVADVPLFMVGLVFSFVSAWLCIRW
HHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRYISSHSFIPFAWYRIAFGVVVLATAWSGVVTWTP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA