| Definition | Polaromonas sp. JS666 chromosome, complete genome. |
|---|---|
| Accession | NC_007948 |
| Length | 5,200,264 |
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The map label for this gene is kduD [H]
Identifier: 91789198
GI number: 91789198
Start: 3538900
End: 3539619
Strand: Reverse
Name: kduD [H]
Synonym: Bpro_3342
Alternate gene names: 91789198
Gene position: 3539619-3538900 (Counterclockwise)
Preceding gene: 91789199
Following gene: 91789197
Centisome position: 68.07
GC content: 70.0
Gene sequence:
>720_bases ATGACTTATCAGGCAGAACTCTTCAAAGGCAAGCGGGCGCTGGTCGCCGGTGCAACACAGGGCATAGGCGCCGTGATTGC CAACCACCTCGCAGCGCTGGGCGCCGAGGTCACGGCTCTCGGGCTGGGGCCGGGCGACGGCACGCTGGACGCGGCGGTCG CCGTGCGGCAGGCCGATGTGACGTCGGCGCAGAGCCTGGACGCGGCGCTGGCCGGCATGGACCAGCTCGACATCGTCTTC AACTGCGCAGGCATCATCAAGCGCGGCGCCGAGCACGACCTGGACGTGTTCGAGCAGGTGCTGGCCGTGAACCTGACCGG CACCATGCGGGTCTGCACCGCGACGCGCGAGCGGCTCAAAGCCAGTCGCGGCTGCATCGTCAACACCGCCTCCATGCTGA GCTTTTTTGGCGGCGGCCTCGTGCCGGGCTATGCGGCCAGCAAGGGCGGAGTGGCGCAGCTCACCAAGTCGCTGGCCATT GCCTATGCTGCAGACGGCATCCGTGTCAACGCCATCGCGCCCGGCTGGATTGCCACACCGCTCACGCAGGCGCTGCAGGA CGACCCGGCACGCGCCGGCCCGATCCTGGCGCGCACGCCGCTGGGCCGCTGGGGCACGCCGGCCGATGTGGCCCAGGCCG CCATGTTCCTGTGCACGCCGGCGGCGGCGTTCATGACCGGCGTGATCCTGCCGGTCGACGGGGGCTACCTGGTGTCCTGA
Upstream 100 bases:
>100_bases GCAGGAAGGGTGCGTGCAGCTATTATTTTGATAGCGTAACGGTGGCTGTCCTGCGCTGGCGAGGCCGCTTTTACACCTAT TCGACAACCCAGGAATCCTC
Downstream 100 bases:
>100_bases TGAATTGCGGGCCGGGCCAGCAGGGATAATCCTTTTTTGCTCATCAGCCCTCACCGCACATCGCCCTGCCCATGCCCGCT TCCCGACCACCTTCCGCTGT
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 239; Mature: 238
Protein sequence:
>239_residues MTYQAELFKGKRALVAGATQGIGAVIANHLAALGAEVTALGLGPGDGTLDAAVAVRQADVTSAQSLDAALAGMDQLDIVF NCAGIIKRGAEHDLDVFEQVLAVNLTGTMRVCTATRERLKASRGCIVNTASMLSFFGGGLVPGYAASKGGVAQLTKSLAI AYAADGIRVNAIAPGWIATPLTQALQDDPARAGPILARTPLGRWGTPADVAQAAMFLCTPAAAFMTGVILPVDGGYLVS
Sequences:
>Translated_239_residues MTYQAELFKGKRALVAGATQGIGAVIANHLAALGAEVTALGLGPGDGTLDAAVAVRQADVTSAQSLDAALAGMDQLDIVF NCAGIIKRGAEHDLDVFEQVLAVNLTGTMRVCTATRERLKASRGCIVNTASMLSFFGGGLVPGYAASKGGVAQLTKSLAI AYAADGIRVNAIAPGWIATPLTQALQDDPARAGPILARTPLGRWGTPADVAQAAMFLCTPAAAFMTGVILPVDGGYLVS >Mature_238_residues TYQAELFKGKRALVAGATQGIGAVIANHLAALGAEVTALGLGPGDGTLDAAVAVRQADVTSAQSLDAALAGMDQLDIVFN CAGIIKRGAEHDLDVFEQVLAVNLTGTMRVCTATRERLKASRGCIVNTASMLSFFGGGLVPGYAASKGGVAQLTKSLAIA YAADGIRVNAIAPGWIATPLTQALQDDPARAGPILARTPLGRWGTPADVAQAAMFLCTPAAAFMTGVILPVDGGYLVS
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=35.0194552529183, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=31.9672131147541, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=33.596837944664, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI59889578, Length=170, Percent_Identity=40.5882352941176, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI40254992, Length=217, Percent_Identity=33.6405529953917, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=30.7392996108949, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI66933014, Length=195, Percent_Identity=28.7179487179487, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=26.6932270916335, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=31.1023622047244, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=30.327868852459, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI5031737, Length=237, Percent_Identity=25.3164556962025, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=35.6862745098039, Blast_Score=133, Evalue=9e-33, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=34.9593495934959, Blast_Score=130, Evalue=6e-32, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=38.1147540983607, Blast_Score=120, Evalue=6e-29, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=31.5573770491803, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=33.59375, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI2367175, Length=193, Percent_Identity=33.6787564766839, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=33.0645161290323, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1786812, Length=241, Percent_Identity=30.2904564315353, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=26.9387755102041, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=29.9610894941634, Blast_Score=67, Evalue=2e-12, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=31.0483870967742, Blast_Score=103, Evalue=5e-23, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=32.5301204819277, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=31.5573770491803, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=31.3253012048193, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=29.7297297297297, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=27.027027027027, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.2442748091603, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=27.3076923076923, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=28.3524904214559, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.5171102661597, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=27.6859504132231, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=26.9961977186312, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=28.1632653061224, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.7992277992278, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=29.6875, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=27.3764258555133, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=26.5917602996255, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=27.4131274131274, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=28.3524904214559, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=30.5555555555556, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=26.5384615384615, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=27.2373540856031, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.9693486590038, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=27.4074074074074, Blast_Score=70, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=30.8880308880309, Blast_Score=70, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17561272, Length=149, Percent_Identity=32.2147651006711, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=30.6122448979592, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=25.4752851711027, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=9e-20, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=32.6612903225806, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=35.5102040816327, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=34.5381526104418, Blast_Score=101, Evalue=3e-22, Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=33.8912133891213, Blast_Score=100, Evalue=6e-22, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=33.6, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=32.8063241106719, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI24644337, Length=170, Percent_Identity=35.8823529411765, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=30.3149606299213, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=1e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 24281; Mature: 24150
Theoretical pI: Translated: 6.50; Mature: 6.50
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYQAELFKGKRALVAGATQGIGAVIANHLAALGAEVTALGLGPGDGTLDAAVAVRQADV CCCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHH TSAQSLDAALAGMDQLDIVFNCAGIIKRGAEHDLDVFEQVLAVNLTGTMRVCTATRERLK HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH ASRGCIVNTASMLSFFGGGLVPGYAASKGGVAQLTKSLAIAYAADGIRVNAIAPGWIATP HHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHEECCCEEEEEECCCHHHHH LTQALQDDPARAGPILARTPLGRWGTPADVAQAAMFLCTPAAAFMTGVILPVDGGYLVS HHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCEECC >Mature Secondary Structure TYQAELFKGKRALVAGATQGIGAVIANHLAALGAEVTALGLGPGDGTLDAAVAVRQADV CCCHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHH TSAQSLDAALAGMDQLDIVFNCAGIIKRGAEHDLDVFEQVLAVNLTGTMRVCTATRERLK HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH ASRGCIVNTASMLSFFGGGLVPGYAASKGGVAQLTKSLAIAYAADGIRVNAIAPGWIATP HHCCCEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHEECCCEEEEEECCCHHHHH LTQALQDDPARAGPILARTPLGRWGTPADVAQAAMFLCTPAAAFMTGVILPVDGGYLVS HHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8760912; 9384377 [H]