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The map label for this gene is kdsA [H]

Identifier: 91789042

GI number: 91789042

Start: 3366721

End: 3367578

Strand: Direct

Name: kdsA [H]

Synonym: Bpro_3182

Alternate gene names: 91789042

Gene position: 3366721-3367578 (Clockwise)

Preceding gene: 91789041

Following gene: 91789043

Centisome position: 64.74

GC content: 61.54

Gene sequence:

>858_bases
ATGAAACTATGCGGATTTGACATTGGTCTGAACCAGCCGTTTTTCCTGATTGCCGGACCCTGCGTGGTGGAGTCCGAACA
GCTCCAGATGGACACGGCCGGCACGCTGAAAGAGATCACTTCGTCGCTGGGCATCCCCTTCATCTTCAAGTCCAGCTACG
ACAAGGCCAACCGCTCCAGCGGCACCAGTTTTCGCGGCCCCGGCATGGTCAAGGGCCTGGAAATCCTCGCCAAGGTCAAA
CGCGAGCTGAACCTGCCCCTCCTGACCGATGTCCATTCGGAAGCCGACATTGCCACCGTCGCCTCCGTGGTCGACGTGTT
GCAAACCCCGGCGTTTTTGTGCCGCCAGACCGACTTCATCCATGCGGTGGCGCAATCGGGCAAGCCGGTCAATATCAAGA
AAGGCCAGTTCCTCGCGCCGGGTGACATGAAGAACGTCATCGACAAGGCGCGGGCGGCAGCACGCGAAAAAGGCCTCAAC
GAAGACAACTTCATGGCCTGCGAGCGCGGTGCCAGTTTTGGCTACAACAACCTGGTGTCCGACATGCGCAGCCTGGCCAT
CATGCGCGAGACGAATGCCCCGGTGGTGTTTGATGCGACCCACTCGGTGCAACTCCCCGGCGGCCAGGGCACCAGCAGCG
GCGGCCAGCGCGAAATGGTGCCGGTGCTGGCACGGGCTGCGGTCGCCGTCGGTGTGGCCGGCCTCTTCATGGAAACGCAT
CCCGATCCGGCCAAGGCCCTGAGCGACGGCCCCAATGCCGTGCCGCTCAAGCACATGAAAGCCCTGCTCGAGACGCTGCT
AGAACTGGACCGCGTGACCAAGAAAAACGGCTACCTTGAAAACAGCTTCGGAGCCTGA

Upstream 100 bases:

>100_bases
CGCTGTTCAATGCCTACATTGCGGCGGTGCTTGAGCACCGCGTCAAGGCCGGCCAGGATGGCAAAGCCACGGCCAAGGCC
CTGAAAGCGGTGGCCTGACC

Downstream 100 bases:

>100_bases
CCGTGCCAAGTGCCTACATCATCGCCAACGTTACAGTTACGAACCCCGAACAATACGAAACCTATAAAAAACTCTCTAGC
ATTGCCATGCAAGTGCACGG

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKLCGFDIGLNQPFFLIAGPCVVESEQLQMDTAGTLKEITSSLGIPFIFKSSYDKANRSSGTSFRGPGMVKGLEILAKVK
RELNLPLLTDVHSEADIATVASVVDVLQTPAFLCRQTDFIHAVAQSGKPVNIKKGQFLAPGDMKNVIDKARAAAREKGLN
EDNFMACERGASFGYNNLVSDMRSLAIMRETNAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETH
PDPAKALSDGPNAVPLKHMKALLETLLELDRVTKKNGYLENSFGA

Sequences:

>Translated_285_residues
MKLCGFDIGLNQPFFLIAGPCVVESEQLQMDTAGTLKEITSSLGIPFIFKSSYDKANRSSGTSFRGPGMVKGLEILAKVK
RELNLPLLTDVHSEADIATVASVVDVLQTPAFLCRQTDFIHAVAQSGKPVNIKKGQFLAPGDMKNVIDKARAAAREKGLN
EDNFMACERGASFGYNNLVSDMRSLAIMRETNAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETH
PDPAKALSDGPNAVPLKHMKALLETLLELDRVTKKNGYLENSFGA
>Mature_285_residues
MKLCGFDIGLNQPFFLIAGPCVVESEQLQMDTAGTLKEITSSLGIPFIFKSSYDKANRSSGTSFRGPGMVKGLEILAKVK
RELNLPLLTDVHSEADIATVASVVDVLQTPAFLCRQTDFIHAVAQSGKPVNIKKGQFLAPGDMKNVIDKARAAAREKGLN
EDNFMACERGASFGYNNLVSDMRSLAIMRETNAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETH
PDPAKALSDGPNAVPLKHMKALLETLLELDRVTKKNGYLENSFGA

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=272, Percent_Identity=45.2205882352941, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 30479; Mature: 30479

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLCGFDIGLNQPFFLIAGPCVVESEQLQMDTAGTLKEITSSLGIPFIFKSSYDKANRSS
CCEECCCCCCCCCEEEEECCEEECHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCC
GTSFRGPGMVKGLEILAKVKRELNLPLLTDVHSEADIATVASVVDVLQTPAFLCRQTDFI
CCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
HAVAQSGKPVNIKKGQFLAPGDMKNVIDKARAAAREKGLNEDNFMACERGASFGYNNLVS
HHHHHCCCCCEECCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHH
DMRSLAIMRETNAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETH
HHHHHHHHHCCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PDPAKALSDGPNAVPLKHMKALLETLLELDRVTKKNGYLENSFGA
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLCGFDIGLNQPFFLIAGPCVVESEQLQMDTAGTLKEITSSLGIPFIFKSSYDKANRSS
CCEECCCCCCCCCEEEEECCEEECHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCC
GTSFRGPGMVKGLEILAKVKRELNLPLLTDVHSEADIATVASVVDVLQTPAFLCRQTDFI
CCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
HAVAQSGKPVNIKKGQFLAPGDMKNVIDKARAAAREKGLNEDNFMACERGASFGYNNLVS
HHHHHCCCCCEECCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHH
DMRSLAIMRETNAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETH
HHHHHHHHHCCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PDPAKALSDGPNAVPLKHMKALLETLLELDRVTKKNGYLENSFGA
CCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA