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The map label for this gene is kdsB [H]

Identifier: 91788811

GI number: 91788811

Start: 3111957

End: 3112772

Strand: Direct

Name: kdsB [H]

Synonym: Bpro_2951

Alternate gene names: 91788811

Gene position: 3111957-3112772 (Clockwise)

Preceding gene: 91788810

Following gene: 91788812

Centisome position: 59.84

GC content: 64.83

Gene sequence:

>816_bases
ATGAGGAACTGGGTCTGTGATGTTTGCCAATTTCCTGCCCGCATGAGCATGCGCTTCACTGTCCTCATCCCGGCCCGCCT
GGCTTCCACGCGCCTGCCCAACAAACCGCTGGCCGACATGGGCGGCGCACCCATGGTCGTGCGGGTGGCGCAGCGTGCCA
TGCAAAGCACAGCTGCCCGCACGGTGGTCGCGACCGACAGCACCGACATCATCGACAAATGCGCGGCGTTTGGCGTTGCA
GCGGTACTGACCCGTGCCGACCATCCCAGCGGCAGCGACCGGCTGGCTGAAGCCTGCACCGCACTCGGCCTGGCTGACGA
TGACATCGTTGTGAATGTGCAGGGTGACGAGCCCCTGATCGACCCGGCCCTGATCGACGCGGTGGCGCGCCTGCTCAATG
AACGCCCTGACTGTGCGATGAGCACGGCGGCGCATTCGATTGACCAGATGGCTGACCTGCTCAATCCCAATGTGGTCAAG
GTGGTGCTGGATGCGCGCCAGACCGCGTTGTACTTCAGCCGTTCGCCCATCCCCGCGGCACGGGACTTTGCCGGCAAACC
CTGGTGGGAAGATGGCGAAAAGGGCTGCAAGCTGCCCAAACCGCTGCGCCACGTCGGCATCTATGGCTATCGCGTCGGCT
TCCTGCGGCAGTTTCCCACCCTGCCCCAGGCCCCGCTGGAGCAACTGGAGTCGCTGGAACAGCTGCGCGCGCTCTGGCAT
GGCCACCGGATTGCCGTGCACATTACCGATGAAGCGCCCGGCCCCGGTGTGGATACGCCGGAAGACCTGGCCAGGGCACG
CCAGTTCTTTCCATAG

Upstream 100 bases:

>100_bases
CGTGAAAAACAGGAACTCATCTCCCGCAGCGCACGGCTGGCCTACCCGGTACGCGACGGGCTGCCGGTGCTGCTGGAAAG
CGAAGCCCGAACCCTGACCG

Downstream 100 bases:

>100_bases
CAGCCCGATCAGCCTGCACCGGCTGTGTAAGCTGCCGTCAGGGGCGTGCATGCTATCCTTGCACAAGAAACAGGCGTGAG
GTTTGCGTGACGTGCCCCTC

Product: 3-deoxy-D-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRNWVCDVCQFPARMSMRFTVLIPARLASTRLPNKPLADMGGAPMVVRVAQRAMQSTAARTVVATDSTDIIDKCAAFGVA
AVLTRADHPSGSDRLAEACTALGLADDDIVVNVQGDEPLIDPALIDAVARLLNERPDCAMSTAAHSIDQMADLLNPNVVK
VVLDARQTALYFSRSPIPAARDFAGKPWWEDGEKGCKLPKPLRHVGIYGYRVGFLRQFPTLPQAPLEQLESLEQLRALWH
GHRIAVHITDEAPGPGVDTPEDLARARQFFP

Sequences:

>Translated_271_residues
MRNWVCDVCQFPARMSMRFTVLIPARLASTRLPNKPLADMGGAPMVVRVAQRAMQSTAARTVVATDSTDIIDKCAAFGVA
AVLTRADHPSGSDRLAEACTALGLADDDIVVNVQGDEPLIDPALIDAVARLLNERPDCAMSTAAHSIDQMADLLNPNVVK
VVLDARQTALYFSRSPIPAARDFAGKPWWEDGEKGCKLPKPLRHVGIYGYRVGFLRQFPTLPQAPLEQLESLEQLRALWH
GHRIAVHITDEAPGPGVDTPEDLARARQFFP
>Mature_271_residues
MRNWVCDVCQFPARMSMRFTVLIPARLASTRLPNKPLADMGGAPMVVRVAQRAMQSTAARTVVATDSTDIIDKCAAFGVA
AVLTRADHPSGSDRLAEACTALGLADDDIVVNVQGDEPLIDPALIDAVARLLNERPDCAMSTAAHSIDQMADLLNPNVVK
VVLDARQTALYFSRSPIPAARDFAGKPWWEDGEKGCKLPKPLRHVGIYGYRVGFLRQFPTLPQAPLEQLESLEQLRALWH
GHRIAVHITDEAPGPGVDTPEDLARARQFFP

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=251, Percent_Identity=49.800796812749, Blast_Score=234, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 29581; Mature: 29581

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNWVCDVCQFPARMSMRFTVLIPARLASTRLPNKPLADMGGAPMVVRVAQRAMQSTAAR
CCCCHHHHHCCCHHCCEEEEEEECHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHH
TVVATDSTDIIDKCAAFGVAAVLTRADHPSGSDRLAEACTALGLADDDIVVNVQGDEPLI
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCC
DPALIDAVARLLNERPDCAMSTAAHSIDQMADLLNPNVVKVVLDARQTALYFSRSPIPAA
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHEECCCCCCHH
RDFAGKPWWEDGEKGCKLPKPLRHVGIYGYRVGFLRQFPTLPQAPLEQLESLEQLRALWH
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GHRIAVHITDEAPGPGVDTPEDLARARQFFP
CCEEEEEEECCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRNWVCDVCQFPARMSMRFTVLIPARLASTRLPNKPLADMGGAPMVVRVAQRAMQSTAAR
CCCCHHHHHCCCHHCCEEEEEEECHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHH
TVVATDSTDIIDKCAAFGVAAVLTRADHPSGSDRLAEACTALGLADDDIVVNVQGDEPLI
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCC
DPALIDAVARLLNERPDCAMSTAAHSIDQMADLLNPNVVKVVLDARQTALYFSRSPIPAA
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHEECCCCCCHH
RDFAGKPWWEDGEKGCKLPKPLRHVGIYGYRVGFLRQFPTLPQAPLEQLESLEQLRALWH
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
GHRIAVHITDEAPGPGVDTPEDLARARQFFP
CCEEEEEEECCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA