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The map label for this gene is pdxA [H]

Identifier: 91788696

GI number: 91788696

Start: 2988565

End: 2989614

Strand: Direct

Name: pdxA [H]

Synonym: Bpro_2835

Alternate gene names: 91788696

Gene position: 2988565-2989614 (Clockwise)

Preceding gene: 91788695

Following gene: 91788697

Centisome position: 57.47

GC content: 65.62

Gene sequence:

>1050_bases
ATGAGCCAACAAACCACACCGGCAACTACACCGGCAGCCACACCGGTCATTGCCCTGACGTTGGGCGATGCTGCAGGCAT
CGGCCCCGAGCTGATTGCGCGGCTGCTGAGCCAGCCCGGCATCACCGCCAACGCCAATATCGTGCTGGTCGGCGACCCCT
GGCTCTGGCAGGACGGCCAGGCCATTGCCAAACTCACCGTGCCCACGCAGGCCGTTGCCAGCCTGGCCGAGGTGCGAAAA
CGCCCCGCCCAGCGCCTACCAGCCTTCCTTGCCGTCGACACCATTCGCCCGGAGCAGGTGCAGCGCAGCCAGGCGCAGGC
CGCTTGCGGCAGCGCGGTGCTGCGGGTGCTCAACCTGTGCATGGACGGCGCCAAGCGCGGCGAGGTCGACGCCATTTGCT
TTGCCCCGCTGAACAAGCAGGCGATGAAGCTGGGCGGCCTGAAGCACGAGGACGAACTGCACCACTTTGCCGAATATCTG
GGCGTGACCGGCTACTTCTGCGAGTTCAACACCCTCGGCGACTTGTGGACCTCGCGCGTGTCCTCGCACATCCCGCTGAA
GGACGCGGCGTCCATGCTCAGCAAGGAGCGCATCGTGGATGCCGCCCGCCTGATTTACCGGTCGCTGCAGGCCAGCGGCA
CCGCCAGCCCCAAAGTGGCGATTGCGGCCTTCAACCCGCACGGCGGGGATGGTGGTATGTGCGGACGCGAAGAGATTGAC
ATCATCGAGCCGGCCGTGCGCGAGTTGCGCGCCAGCGGCTTTCCGGTCGATGGCCCCTTCCCCGCCGACACCATCTTTCT
CAAGGCGCGCGATGGTCAGTACCAGGCCATCGTCACCATGTACCACGACCAAGGGCAGATTGCCATCAAGCTCATGGGCT
TCAGCAAGGGCGTGACGGTGCAAGGCGGCTTGCCGGTGCCCATCACCACGCCGGCACACGGCACGGCTTATGACATTGCG
GGTCAGGGTGTGGCCGATGTGAATGCCACGCTCAACGCCTTTCAGATTGCCCAGCGCATGGGTACCGCCCGGCGGGAGCA
GACTGCTTGA

Upstream 100 bases:

>100_bases
ACACCGATGACGCAGGCGCAATTCGCCCAGTTTCACACTGCTGAAAACAAACGCTACGGCGACCTGATCGCCAAAAAGAA
CATCAGACTGGATTGAACCC

Downstream 100 bases:

>100_bases
GTGTTCACAGTCTCGCTACAACAAGCGACACATTCATTTTTTTAATCCGTTAAAGAATCATCATGAAAATCAAATCAGTT
CGCGCGCGTGTGTTTGAGTG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase 2 [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSQQTTPATTPAATPVIALTLGDAAGIGPELIARLLSQPGITANANIVLVGDPWLWQDGQAIAKLTVPTQAVASLAEVRK
RPAQRLPAFLAVDTIRPEQVQRSQAQAACGSAVLRVLNLCMDGAKRGEVDAICFAPLNKQAMKLGGLKHEDELHHFAEYL
GVTGYFCEFNTLGDLWTSRVSSHIPLKDAASMLSKERIVDAARLIYRSLQASGTASPKVAIAAFNPHGGDGGMCGREEID
IIEPAVRELRASGFPVDGPFPADTIFLKARDGQYQAIVTMYHDQGQIAIKLMGFSKGVTVQGGLPVPITTPAHGTAYDIA
GQGVADVNATLNAFQIAQRMGTARREQTA

Sequences:

>Translated_349_residues
MSQQTTPATTPAATPVIALTLGDAAGIGPELIARLLSQPGITANANIVLVGDPWLWQDGQAIAKLTVPTQAVASLAEVRK
RPAQRLPAFLAVDTIRPEQVQRSQAQAACGSAVLRVLNLCMDGAKRGEVDAICFAPLNKQAMKLGGLKHEDELHHFAEYL
GVTGYFCEFNTLGDLWTSRVSSHIPLKDAASMLSKERIVDAARLIYRSLQASGTASPKVAIAAFNPHGGDGGMCGREEID
IIEPAVRELRASGFPVDGPFPADTIFLKARDGQYQAIVTMYHDQGQIAIKLMGFSKGVTVQGGLPVPITTPAHGTAYDIA
GQGVADVNATLNAFQIAQRMGTARREQTA
>Mature_348_residues
SQQTTPATTPAATPVIALTLGDAAGIGPELIARLLSQPGITANANIVLVGDPWLWQDGQAIAKLTVPTQAVASLAEVRKR
PAQRLPAFLAVDTIRPEQVQRSQAQAACGSAVLRVLNLCMDGAKRGEVDAICFAPLNKQAMKLGGLKHEDELHHFAEYLG
VTGYFCEFNTLGDLWTSRVSSHIPLKDAASMLSKERIVDAARLIYRSLQASGTASPKVAIAAFNPHGGDGGMCGREEIDI
IEPAVRELRASGFPVDGPFPADTIFLKARDGQYQAIVTMYHDQGQIAIKLMGFSKGVTVQGGLPVPITTPAHGTAYDIAG
QGVADVNATLNAFQIAQRMGTARREQTA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=325, Percent_Identity=30.4615384615385, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37032; Mature: 36901

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQTTPATTPAATPVIALTLGDAAGIGPELIARLLSQPGITANANIVLVGDPWLWQDGQ
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCEECCCC
AIAKLTVPTQAVASLAEVRKRPAQRLPAFLAVDTIRPEQVQRSQAQAACGSAVLRVLNLC
EEEEEECCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
MDGAKRGEVDAICFAPLNKQAMKLGGLKHEDELHHFAEYLGVTGYFCEFNTLGDLWTSRV
HCCCCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
SSHIPLKDAASMLSKERIVDAARLIYRSLQASGTASPKVAIAAFNPHGGDGGMCGREEID
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCHH
IIEPAVRELRASGFPVDGPFPADTIFLKARDGQYQAIVTMYHDQGQIAIKLMGFSKGVTV
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCEEEEEEEECCCCEEE
QGGLPVPITTPAHGTAYDIAGQGVADVNATLNAFQIAQRMGTARREQTA
ECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQTTPATTPAATPVIALTLGDAAGIGPELIARLLSQPGITANANIVLVGDPWLWQDGQ
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCEECCCC
AIAKLTVPTQAVASLAEVRKRPAQRLPAFLAVDTIRPEQVQRSQAQAACGSAVLRVLNLC
EEEEEECCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
MDGAKRGEVDAICFAPLNKQAMKLGGLKHEDELHHFAEYLGVTGYFCEFNTLGDLWTSRV
HCCCCCCCCCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
SSHIPLKDAASMLSKERIVDAARLIYRSLQASGTASPKVAIAAFNPHGGDGGMCGREEID
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCHH
IIEPAVRELRASGFPVDGPFPADTIFLKARDGQYQAIVTMYHDQGQIAIKLMGFSKGVTV
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCEEEEEEEECCCCEEE
QGGLPVPITTPAHGTAYDIAGQGVADVNATLNAFQIAQRMGTARREQTA
ECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]