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The map label for this gene is nuoF2 [H]

Identifier: 91788666

GI number: 91788666

Start: 2946008

End: 2947708

Strand: Direct

Name: nuoF2 [H]

Synonym: Bpro_2804

Alternate gene names: 91788666

Gene position: 2946008-2947708 (Clockwise)

Preceding gene: 91788665

Following gene: 91788667

Centisome position: 56.65

GC content: 65.78

Gene sequence:

>1701_bases
ATGAACCATCCCATCATCCCTATTGCCGTCGTGCAAGCCGCTTCCAAAGAGCGAAAACGCCAGGCACCCAAGGGACGCCG
CGTGGAGCCGAGCGCGCTGGCCGACGTGCAACGCCTGCTGGGCTCCGAGTCGCGTCAGGCCGATCTGCTCATAGAGCACC
TGCACAAGATCCAGGATCACTTTGGCCACCTGTCGGCAGCCCACCTGGCGGCGCTGGCGCAAGAGATGCGCCTGGCGCAA
ACCGAGGTGTATGAGGTCGCAACTTTTTACCATCATTTCGACGTGGTCAAGGAAGGCGAAGCCGCGCCGGCGCCCCTCAC
CGTGCGTGTGTGCGATGGTCTGTCCTGCGAGATGGCGGGCGCACGTGATTTACTGGACCGGCTCCCGGCCCTACTGGGCC
GCGAGGTACGCGTGATCGCGGCACCTTGCATCGGCCGCTGCGAGCAGGCGCCTGCCGCGGTGGTTGGCCAAAACCCCGTA
CCGAACGCCACCGCAGAGGCCGTCGTGGCCACCGTGGCAGCGAGGGCTGTACAGCACGCCCCCGAAGGCTTTTTCGACTT
TTCCAGCTACCGGGCCGCCGGCGGTTATGCGCTGCTCGCGCAATGCGTCTCGGGAGACCGCGACGTCGAATCAGTCCTCA
AGACCATGGAAGATTCGGGCCTGCGCGGCCTGGGTGGTGCCGGTTTTCCGGCCGGCCGCAAGTGGCGCATCGTCCGCGCC
GAAGCCGGCCCGCGCCTGATGGCGGTCAACATCGACGAGGGCGAACCGGGTACCTTCAAGGACCGTGTCTACCTCGAACG
CGACCCGCACCGCTTCCTTGAAGGCATGCTGATCGCCGCCTGGGCGGTGGGTATCGAGAAGATCTACATCTACCTGCGCG
ACGAATACCATGGCTGCCGCGCCATGCTCGAAACCGAGCTGGACAAACTCAGGCTGGCACCGCCGATGGCCGGCATGCCG
CAAATCGAGTTGCGCCGTGGCGCCGGCGCCTACATCTGCGGCGAAGAGTCGGCCATGATCGAATCGATCGAAGGCAAGCG
CGGCATGCCGCGGCTGCGCCCACCCTATGTGGCGCAAGTGGGCCTGTTCGGCCGCCCGACGCTGGAACACAACTTCGAGA
CCCTGTTCTGGGTCCGCGAGATCCTGGAAAAAGGCGGCGCCTGGTTTACCTCGCACGGCCGCAATGGGCGCAAGGGACTG
CGCTCGTTCTCGGTCTCGGGTCGCGTGAAGAGCCCGGGGGTCAAACTGGCGCCGGCGGGCATCACCATCCAGGAACTGAT
CGACGAACACTGCGGCGGAATGCAGGACGGGCACACCTTCTACGCCTACCTGCCGGGCGGCGCCTCGGGCGGCATCCTGC
CGGCCACCATGAACAGCATCCCGCTGGATTTCGACACACTGCAGCCCTACGGCTGCTTCATCGGGTCGGCCGCCGTGATC
GTGCTGTCCGACCAGGACACCGCCACCAATGCGGCGCGCAACATGATGCGCTTCTTCCACCACGAGTCCTGCGGCCAGTG
CACGCCCTGCCGCGTCGGCACGGCCAAGGCCGCGCACCTGATGGAAAAGCCCAAATGGGACCTCGCACTGCTGGCAGACC
TGTCGCTGGTCATGCGCGACGCATCGATCTGCGGGCTGGGCCAAGCGGCGCCCAACCCGATGGACTGCGTCGTCAAATAT
TTTCCGCACGAGCTGGCCTGA

Upstream 100 bases:

>100_bases
AGAACGGGTGATCTGAACCACGCGCAAAGTACCGGCGAGCCCGCGGCGCGAGCGTCCTGCGAGTCGATTCCAAACAAAAT
GCAAATGTAAGCGAGCCCCC

Downstream 100 bases:

>100_bases
CCGCCACACGGCCAACAAGACAAAGGGCAACGTCATGAATGCAATTACCCGACAGGAACTCGCCGAACTCGACGTGCCGC
TCGTGAGCTTCAGCCTCAAC

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit F 2; NDH-1 subunit F 2 [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MNHPIIPIAVVQAASKERKRQAPKGRRVEPSALADVQRLLGSESRQADLLIEHLHKIQDHFGHLSAAHLAALAQEMRLAQ
TEVYEVATFYHHFDVVKEGEAAPAPLTVRVCDGLSCEMAGARDLLDRLPALLGREVRVIAAPCIGRCEQAPAAVVGQNPV
PNATAEAVVATVAARAVQHAPEGFFDFSSYRAAGGYALLAQCVSGDRDVESVLKTMEDSGLRGLGGAGFPAGRKWRIVRA
EAGPRLMAVNIDEGEPGTFKDRVYLERDPHRFLEGMLIAAWAVGIEKIYIYLRDEYHGCRAMLETELDKLRLAPPMAGMP
QIELRRGAGAYICGEESAMIESIEGKRGMPRLRPPYVAQVGLFGRPTLEHNFETLFWVREILEKGGAWFTSHGRNGRKGL
RSFSVSGRVKSPGVKLAPAGITIQELIDEHCGGMQDGHTFYAYLPGGASGGILPATMNSIPLDFDTLQPYGCFIGSAAVI
VLSDQDTATNAARNMMRFFHHESCGQCTPCRVGTAKAAHLMEKPKWDLALLADLSLVMRDASICGLGQAAPNPMDCVVKY
FPHELA

Sequences:

>Translated_566_residues
MNHPIIPIAVVQAASKERKRQAPKGRRVEPSALADVQRLLGSESRQADLLIEHLHKIQDHFGHLSAAHLAALAQEMRLAQ
TEVYEVATFYHHFDVVKEGEAAPAPLTVRVCDGLSCEMAGARDLLDRLPALLGREVRVIAAPCIGRCEQAPAAVVGQNPV
PNATAEAVVATVAARAVQHAPEGFFDFSSYRAAGGYALLAQCVSGDRDVESVLKTMEDSGLRGLGGAGFPAGRKWRIVRA
EAGPRLMAVNIDEGEPGTFKDRVYLERDPHRFLEGMLIAAWAVGIEKIYIYLRDEYHGCRAMLETELDKLRLAPPMAGMP
QIELRRGAGAYICGEESAMIESIEGKRGMPRLRPPYVAQVGLFGRPTLEHNFETLFWVREILEKGGAWFTSHGRNGRKGL
RSFSVSGRVKSPGVKLAPAGITIQELIDEHCGGMQDGHTFYAYLPGGASGGILPATMNSIPLDFDTLQPYGCFIGSAAVI
VLSDQDTATNAARNMMRFFHHESCGQCTPCRVGTAKAAHLMEKPKWDLALLADLSLVMRDASICGLGQAAPNPMDCVVKY
FPHELA
>Mature_566_residues
MNHPIIPIAVVQAASKERKRQAPKGRRVEPSALADVQRLLGSESRQADLLIEHLHKIQDHFGHLSAAHLAALAQEMRLAQ
TEVYEVATFYHHFDVVKEGEAAPAPLTVRVCDGLSCEMAGARDLLDRLPALLGREVRVIAAPCIGRCEQAPAAVVGQNPV
PNATAEAVVATVAARAVQHAPEGFFDFSSYRAAGGYALLAQCVSGDRDVESVLKTMEDSGLRGLGGAGFPAGRKWRIVRA
EAGPRLMAVNIDEGEPGTFKDRVYLERDPHRFLEGMLIAAWAVGIEKIYIYLRDEYHGCRAMLETELDKLRLAPPMAGMP
QIELRRGAGAYICGEESAMIESIEGKRGMPRLRPPYVAQVGLFGRPTLEHNFETLFWVREILEKGGAWFTSHGRNGRKGL
RSFSVSGRVKSPGVKLAPAGITIQELIDEHCGGMQDGHTFYAYLPGGASGGILPATMNSIPLDFDTLQPYGCFIGSAAVI
VLSDQDTATNAARNMMRFFHHESCGQCTPCRVGTAKAAHLMEKPKWDLALLADLSLVMRDASICGLGQAAPNPMDCVVKY
FPHELA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=372, Percent_Identity=38.4408602150538, Blast_Score=252, Evalue=6e-67,
Organism=Homo sapiens, GI260656005, Length=372, Percent_Identity=38.4408602150538, Blast_Score=252, Evalue=8e-67,
Organism=Escherichia coli, GI1788620, Length=395, Percent_Identity=34.9367088607595, Blast_Score=232, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17531727, Length=450, Percent_Identity=35.5555555555556, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI19920794, Length=376, Percent_Identity=37.2340425531915, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI45550452, Length=374, Percent_Identity=35.8288770053476, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24653819, Length=379, Percent_Identity=32.7176781002639, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653817, Length=356, Percent_Identity=30.6179775280899, Blast_Score=166, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 61492; Mature: 61492

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00644 COMPLEX1_51K_1 ; PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPIIPIAVVQAASKERKRQAPKGRRVEPSALADVQRLLGSESRQADLLIEHLHKIQDH
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FGHLSAAHLAALAQEMRLAQTEVYEVATFYHHFDVVKEGEAAPAPLTVRVCDGLSCEMAG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
ARDLLDRLPALLGREVRVIAAPCIGRCEQAPAAVVGQNPVPNATAEAVVATVAARAVQHA
HHHHHHHHHHHHCCCEEEEECCHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHC
PEGFFDFSSYRAAGGYALLAQCVSGDRDVESVLKTMEDSGLRGLGGAGFPAGRKWRIVRA
CCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEE
EAGPRLMAVNIDEGEPGTFKDRVYLERDPHRFLEGMLIAAWAVGIEKIYIYLRDEYHGCR
CCCCEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHH
AMLETELDKLRLAPPMAGMPQIELRRGAGAYICGEESAMIESIEGKRGMPRLRPPYVAQV
HHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEECCCHHHHHHHCCCCCCCCCCCCHHEEE
GLFGRPTLEHNFETLFWVREILEKGGAWFTSHGRNGRKGLRSFSVSGRVKSPGVKLAPAG
CCCCCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCCCCCCCCCEEECCC
ITIQELIDEHCGGMQDGHTFYAYLPGGASGGILPATMNSIPLDFDTLQPYGCFIGSAAVI
CCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHEECCEEEE
VLSDQDTATNAARNMMRFFHHESCGQCTPCRVGTAKAAHLMEKPKWDLALLADLSLVMRD
EECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHC
ASICGLGQAAPNPMDCVVKYFPHELA
CHHCCCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MNHPIIPIAVVQAASKERKRQAPKGRRVEPSALADVQRLLGSESRQADLLIEHLHKIQDH
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FGHLSAAHLAALAQEMRLAQTEVYEVATFYHHFDVVKEGEAAPAPLTVRVCDGLSCEMAG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
ARDLLDRLPALLGREVRVIAAPCIGRCEQAPAAVVGQNPVPNATAEAVVATVAARAVQHA
HHHHHHHHHHHHCCCEEEEECCHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHC
PEGFFDFSSYRAAGGYALLAQCVSGDRDVESVLKTMEDSGLRGLGGAGFPAGRKWRIVRA
CCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEE
EAGPRLMAVNIDEGEPGTFKDRVYLERDPHRFLEGMLIAAWAVGIEKIYIYLRDEYHGCR
CCCCEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHH
AMLETELDKLRLAPPMAGMPQIELRRGAGAYICGEESAMIESIEGKRGMPRLRPPYVAQV
HHHHHHHHHHCCCCCCCCCCCCEEECCCCEEEECCCHHHHHHHCCCCCCCCCCCCHHEEE
GLFGRPTLEHNFETLFWVREILEKGGAWFTSHGRNGRKGLRSFSVSGRVKSPGVKLAPAG
CCCCCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHCCCCCCCCCCCCEEECCC
ITIQELIDEHCGGMQDGHTFYAYLPGGASGGILPATMNSIPLDFDTLQPYGCFIGSAAVI
CCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHEECCEEEE
VLSDQDTATNAARNMMRFFHHESCGQCTPCRVGTAKAAHLMEKPKWDLALLADLSLVMRD
EECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHC
ASICGLGQAAPNPMDCVVKYFPHELA
CHHCCCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]