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The map label for this gene is btuB [H]

Identifier: 91788648

GI number: 91788648

Start: 2927057

End: 2928991

Strand: Reverse

Name: btuB [H]

Synonym: Bpro_2786

Alternate gene names: 91788648

Gene position: 2928991-2927057 (Counterclockwise)

Preceding gene: 91788652

Following gene: 91788647

Centisome position: 56.32

GC content: 58.81

Gene sequence:

>1935_bases
ATGAAAATCAGTGTTTTTCCCGTACGTCTTTCCGTGCTTGTCTTGTCGTTGCCCGCCGTTTCTGCGGTGCTGGCGCAAAC
CGGCCCGGCCCCCGCCTTGAACGAAGTGGTGGTGACGGGCAGCCGCGTGGCCGGGCCCCGCGAATCGCAGCCCTTTGGCA
CAAGTGTCATCACGGATGTAGATATTCAGCGGATTGGGGCCGCCACCGTGAACGATGCCATCATGCGCCTGCTGGGTGTC
GTTGGCCGTCAGGATTTCTACGGCGGTGGAGACTATGCCCTGGATTTGCGGGGCTTCGGGAGCACCGCCAGCAGTAACCA
GGTCGTGATTGTGGACGGTGTTCGCATCAATGAGGCCGATTTGAGTGGCACCCGCCTGGCTGGCATCCCGATTGAATCCG
TATTACAAATCGAAGTTATTCGCGGCAGCGGCGCGGTCTTGTACGGGGAGGGCGCGACCGGCGGCGTCATTATCGTCACC
ACCAAGGCAGGAGCCGGCGCGGCTCGTAAAAATGCGGCGTCTCTGTATGCCGGCGCTGGGAGCTACGGGCTGCGCGAGGG
GCGTGCCAACGCGACGCTGGCCAGCGGAGGATTTTCGTTGGATGTCAATGCAATGAACCGCAAGGCTGACAACCACCGCG
ATAACTTCCGCTCTGAAACCGATGCGGTATCCGCGGTTGCACAGTGGAGCAACGAGTGGCTGCGCCTGGGCGCAAGTCGG
GCACAAGACAGTCTGGACACCGGGCTGCCTGGCGGGCTGACGGCGGCGCAGTACCAAAATAATCCCCGTCAGACCACGAC
CCCCCAAAGCAAGGCGTCCATTGACAATGTTCGCAATGGCCTGTTTGCTGAAGCCGCTTTGGGCGATTGGCAACTTTTGG
CCGATGCTGGCTGGCGTGACAAAAAACTGCGCAGTGTGTCAGCTTTTGGCGCCTTCGACTATGACGTCAAGGCCACCAAC
TACGGACTGCGCGCTGTGCACAGTGCCAAACAGTCCGTCTTTTCAAACAGGCTCGTGCTCGGGACCGATTATGCAAGCTG
GCAGCGCGAGGTGCTCGGTGGTTCCACCGCAACGCAGGCTTCACGCGCGTTTTATTTTCGTGATGAGCTGACAGTTGCTT
CCATAGGCACCGTCTTGTCAGTGGGGGCACGTACAGAGCGCATTAAAAAAGACATCGCAGGTACTTCGTCAGGTCTTGCC
GATCGCCAGAATGCCTGGGAGCTGGGACTGAATCAGCCATTGAATAAAGAGGTTTCCGTTTATGGGCGCGTGGGCCGCAG
CTTTCGACTGGCCAATGCTGATGAATTTAATTTCACCTCGCCCGGCGTGACCTTGTTGCCGCAGCGCTCCACCGATGTCG
AGATTGGCTCGCGCTATGCCTCGGGGCGAGTGAAAATGGAGGCACGCTTGTACCGCAGTTCCTTGACCAATGAGATCGGC
TTCGATCCGAATGCGGCAGGTCCATTCGGCCGCGGCGCCAACGTGAACTTTGACCCGACCCGCCGCTCTGGTCTTGAACT
CGATGGCAGCTACGCTTACGCAGAAAACCTGAAGCTGCGCGTGAATGCCGCGCTGCGAAAATCCACATTTTCATCGGGTC
CGTATGCCGGTAAGGATGTACCGCTCGCACCCAATCGAACCTTTGCAGCGCATGCGGATTGGACGCCTGTGGCCGGACAT
CTTGTCAGCGGCGGTCTGAACTGGGTGTCGTCGCAGCATCCAGACTTTGCAAACCAGTGTTCCATCCCAGCCTACACCAC
GGCAGATGCACGCTACGCGTACCAGTGGCAAAAGGCCGAAGTTTCACTCGGCATCACTAACCTGTTTGACCGCAAGTTCT
ATACGCAGGCTTTTCGATGCGCCGCTGGCGTGACGAATTCCATCTATCCTGAAGCGGGGCGTGCAATCGTCGCTGCGGTG
CGGATTAAGTTCTAG

Upstream 100 bases:

>100_bases
ACAAGGTGAACGTGTGCGTCGATCATTTGACGCAGGCATTTGTAACGCTCATGCACTGGCGGGGAAGCCGGTGAGGGCAT
TTTGTTGATTGTCTGACCCC

Downstream 100 bases:

>100_bases
AGGTTCTGGAGTAAGTCATCCATGCCGGATCGTTAAGCGCAATCCCAACAGACCATGTCCGCCTCCACCTGCCCCGCCAT
TCTTGTCGCCGCCCCGGCCT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MKISVFPVRLSVLVLSLPAVSAVLAQTGPAPALNEVVVTGSRVAGPRESQPFGTSVITDVDIQRIGAATVNDAIMRLLGV
VGRQDFYGGGDYALDLRGFGSTASSNQVVIVDGVRINEADLSGTRLAGIPIESVLQIEVIRGSGAVLYGEGATGGVIIVT
TKAGAGAARKNAASLYAGAGSYGLREGRANATLASGGFSLDVNAMNRKADNHRDNFRSETDAVSAVAQWSNEWLRLGASR
AQDSLDTGLPGGLTAAQYQNNPRQTTTPQSKASIDNVRNGLFAEAALGDWQLLADAGWRDKKLRSVSAFGAFDYDVKATN
YGLRAVHSAKQSVFSNRLVLGTDYASWQREVLGGSTATQASRAFYFRDELTVASIGTVLSVGARTERIKKDIAGTSSGLA
DRQNAWELGLNQPLNKEVSVYGRVGRSFRLANADEFNFTSPGVTLLPQRSTDVEIGSRYASGRVKMEARLYRSSLTNEIG
FDPNAAGPFGRGANVNFDPTRRSGLELDGSYAYAENLKLRVNAALRKSTFSSGPYAGKDVPLAPNRTFAAHADWTPVAGH
LVSGGLNWVSSQHPDFANQCSIPAYTTADARYAYQWQKAEVSLGITNLFDRKFYTQAFRCAAGVTNSIYPEAGRAIVAAV
RIKF

Sequences:

>Translated_644_residues
MKISVFPVRLSVLVLSLPAVSAVLAQTGPAPALNEVVVTGSRVAGPRESQPFGTSVITDVDIQRIGAATVNDAIMRLLGV
VGRQDFYGGGDYALDLRGFGSTASSNQVVIVDGVRINEADLSGTRLAGIPIESVLQIEVIRGSGAVLYGEGATGGVIIVT
TKAGAGAARKNAASLYAGAGSYGLREGRANATLASGGFSLDVNAMNRKADNHRDNFRSETDAVSAVAQWSNEWLRLGASR
AQDSLDTGLPGGLTAAQYQNNPRQTTTPQSKASIDNVRNGLFAEAALGDWQLLADAGWRDKKLRSVSAFGAFDYDVKATN
YGLRAVHSAKQSVFSNRLVLGTDYASWQREVLGGSTATQASRAFYFRDELTVASIGTVLSVGARTERIKKDIAGTSSGLA
DRQNAWELGLNQPLNKEVSVYGRVGRSFRLANADEFNFTSPGVTLLPQRSTDVEIGSRYASGRVKMEARLYRSSLTNEIG
FDPNAAGPFGRGANVNFDPTRRSGLELDGSYAYAENLKLRVNAALRKSTFSSGPYAGKDVPLAPNRTFAAHADWTPVAGH
LVSGGLNWVSSQHPDFANQCSIPAYTTADARYAYQWQKAEVSLGITNLFDRKFYTQAFRCAAGVTNSIYPEAGRAIVAAV
RIKF
>Mature_644_residues
MKISVFPVRLSVLVLSLPAVSAVLAQTGPAPALNEVVVTGSRVAGPRESQPFGTSVITDVDIQRIGAATVNDAIMRLLGV
VGRQDFYGGGDYALDLRGFGSTASSNQVVIVDGVRINEADLSGTRLAGIPIESVLQIEVIRGSGAVLYGEGATGGVIIVT
TKAGAGAARKNAASLYAGAGSYGLREGRANATLASGGFSLDVNAMNRKADNHRDNFRSETDAVSAVAQWSNEWLRLGASR
AQDSLDTGLPGGLTAAQYQNNPRQTTTPQSKASIDNVRNGLFAEAALGDWQLLADAGWRDKKLRSVSAFGAFDYDVKATN
YGLRAVHSAKQSVFSNRLVLGTDYASWQREVLGGSTATQASRAFYFRDELTVASIGTVLSVGARTERIKKDIAGTSSGLA
DRQNAWELGLNQPLNKEVSVYGRVGRSFRLANADEFNFTSPGVTLLPQRSTDVEIGSRYASGRVKMEARLYRSSLTNEIG
FDPNAAGPFGRGANVNFDPTRRSGLELDGSYAYAENLKLRVNAALRKSTFSSGPYAGKDVPLAPNRTFAAHADWTPVAGH
LVSGGLNWVSSQHPDFANQCSIPAYTTADARYAYQWQKAEVSLGITNLFDRKFYTQAFRCAAGVTNSIYPEAGRAIVAAV
RIKF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790743, Length=693, Percent_Identity=21.5007215007215, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790405, Length=154, Percent_Identity=37.6623376623377, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787723, Length=320, Percent_Identity=29.0625, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788478, Length=162, Percent_Identity=30.8641975308642, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 68611; Mature: 68611

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVFPVRLSVLVLSLPAVSAVLAQTGPAPALNEVVVTGSRVAGPRESQPFGTSVITDV
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECC
DIQRIGAATVNDAIMRLLGVVGRQDFYGGGDYALDLRGFGSTASSNQVVIVDGVRINEAD
CHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECEEEECCC
LSGTRLAGIPIESVLQIEVIRGSGAVLYGEGATGGVIIVTTKAGAGAARKNAASLYAGAG
CCCCEEECCCCCCEEEEEEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCCHHEEECCC
SYGLREGRANATLASGGFSLDVNAMNRKADNHRDNFRSETDAVSAVAQWSNEWLRLGASR
CCCCCCCCCCCEEECCCCEEEEHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCHHH
AQDSLDTGLPGGLTAAQYQNNPRQTTTPQSKASIDNVRNGLFAEAALGDWQLLADAGWRD
HHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCEEHHCCCCEEEEECCCCCC
KKLRSVSAFGAFDYDVKATNYGLRAVHSAKQSVFSNRLVLGTDYASWQREVLGGSTATQA
HHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCHHHH
SRAFYFRDELTVASIGTVLSVGARTERIKKDIAGTSSGLADRQNAWELGLNQPLNKEVSV
HHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHH
YGRVGRSFRLANADEFNFTSPGVTLLPQRSTDVEIGSRYASGRVKMEARLYRSSLTNEIG
HHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCEECCCEEEHHHHHHHHHHHHHCC
FDPNAAGPFGRGANVNFDPTRRSGLELDGSYAYAENLKLRVNAALRKSTFSSGPYAGKDV
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEECCCEEEEEEHHHHCCCCCCCCCCCCC
PLAPNRTFAAHADWTPVAGHLVSGGLNWVSSQHPDFANQCSIPAYTTADARYAYQWQKAE
CCCCCCCEEECCCCCCHHHHHHHCCCHHCCCCCCCCHHCCCCCEEECCCCEEEEEEEEEE
VSLGITNLFDRKFYTQAFRCAAGVTNSIYPEAGRAIVAAVRIKF
EEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MKISVFPVRLSVLVLSLPAVSAVLAQTGPAPALNEVVVTGSRVAGPRESQPFGTSVITDV
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECC
DIQRIGAATVNDAIMRLLGVVGRQDFYGGGDYALDLRGFGSTASSNQVVIVDGVRINEAD
CHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECEEEECCC
LSGTRLAGIPIESVLQIEVIRGSGAVLYGEGATGGVIIVTTKAGAGAARKNAASLYAGAG
CCCCEEECCCCCCEEEEEEEECCCEEEECCCCCCCEEEEEECCCCCCCCCCCHHEEECCC
SYGLREGRANATLASGGFSLDVNAMNRKADNHRDNFRSETDAVSAVAQWSNEWLRLGASR
CCCCCCCCCCCEEECCCCEEEEHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCHHH
AQDSLDTGLPGGLTAAQYQNNPRQTTTPQSKASIDNVRNGLFAEAALGDWQLLADAGWRD
HHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCEEHHCCCCEEEEECCCCCC
KKLRSVSAFGAFDYDVKATNYGLRAVHSAKQSVFSNRLVLGTDYASWQREVLGGSTATQA
HHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCHHHH
SRAFYFRDELTVASIGTVLSVGARTERIKKDIAGTSSGLADRQNAWELGLNQPLNKEVSV
HHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHH
YGRVGRSFRLANADEFNFTSPGVTLLPQRSTDVEIGSRYASGRVKMEARLYRSSLTNEIG
HHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCEECCCEEEHHHHHHHHHHHHHCC
FDPNAAGPFGRGANVNFDPTRRSGLELDGSYAYAENLKLRVNAALRKSTFSSGPYAGKDV
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEECCCEEEEEEHHHHCCCCCCCCCCCCC
PLAPNRTFAAHADWTPVAGHLVSGGLNWVSSQHPDFANQCSIPAYTTADARYAYQWQKAE
CCCCCCCEEECCCCCCHHHHHHHCCCHHCCCCCCCCHHCCCCCEEECCCCEEEEEEEEEE
VSLGITNLFDRKFYTQAFRCAAGVTNSIYPEAGRAIVAAVRIKF
EEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA