Click here to switch to the map view.

The map label for this gene is aceE [H]

Identifier: 91788534

GI number: 91788534

Start: 2808568

End: 2811309

Strand: Reverse

Name: aceE [H]

Synonym: Bpro_2672

Alternate gene names: 91788534

Gene position: 2811309-2808568 (Counterclockwise)

Preceding gene: 91788538

Following gene: 91788533

Centisome position: 54.06

GC content: 60.69

Gene sequence:

>2742_bases
ATGGCTGCCAATCCAAATGAAGCCGGTGCCGACAACCTACGCGCCGCCGCGAACGATGCCTTGGGTGAGAACACCCTGGA
CAAAGACAAGCAGGAGACCCGGGAGTGGATGGATGCCCTCTCGGCGGTCATTGAAAGCGAGGGCCCGGAACGTGCCCACT
TCCTGCTTGAGCAACTGCTCGAACATGCCCGCCAGAAAAGCATTGACATGCCTTTCTCGGCCAACACCGCTTACGTCAAC
ACCATAGAAACCGACCAGGAAGAGCGCTCCCCCGGCAACCTCGAAATTGAAGAACGCCTGCGCGCCTACATGCGCTGGAA
TGCCATGGCCATGGTGGTCAAGGCCAACCGCCTGCATCCCGCGGATGGCGGCGATCTGGGTGGACATATCGGCTCGTTTG
CCTCGCTGGCCAGTCTCTTTGGTGCGGGCTTCAACCACTTCTGGCATGCCGAGAGCGAGAACCATGGCGGCGATTGCCTC
TACATCCAGGGGCATGTGTCGCCTGGCGTCTACGCACGCGCTTACCTTGAAGGCCGCCTGACGGAAGAGCAACTGCTCAA
TTTCCGCCAGGAAGTTGCTGGCAAGGGGCTTTCCAGCTACCCGCACCCCAAGCTGATGCCCGAATTCTGGCAGTTCCCCA
CGGTCTCCATGGGCCTGGGCCCCCTGATGGCGATTTACCAGGCCAGGTTCCTCAAGTACCTGCACGCCCGCGGTATTGCC
AACACCGAAAACCGCAAGGTCTGGGTGTTCTGTGGCGACGGTGAGATGGATGAAGTCGAATCGATGGGCGCCATCGGGCT
GGCCGCGCGCGAGAAGCTCGACAACCTGGTGTTCGTCATCAACTGCAACCTGCAGCGTCTGGACGGCCCGGTCCGCGGCA
ACGGCAAGATCATCCAGGAACTCGAAGGCGAGTTCCGCGGCGCCGGCTGGAATGTCATCAAGCTGATCTGGGGCAGCAAC
TGGGATCCATTGCTGGCGCGCGACAAGGACGGCGCCTTGCGCAAAGTCATGATTGACACGCTGGACGGCGACTACCAGGC
CATGAAGGCCAACGACGGCGCCTACGTGCGCAAGCATTTCTTTGGCCAGAACCCCAAGACGCTGGAGATGGTCTCCAAGA
TGAGCGACGACGACATCTGGAACCTGCGCCGTGGCGGCCACGACTCGCAAAAGGTGTATGCGGCATTCCATGCGGCCGTC
AATCACACCGGCCAGCCCACAGTGCTGCTGATCAAGACCGTCAAGGGTTTTGGCATGGGCAAGATTGGCGAGGGCAAAAA
CACGGTGCATCAGACCAAGAAACTGACGGACGATGACATCAAGATCTTCCGCGACCGCTTCAACATCCCGATTCCCGACA
GCCAGCTGGCCGACCTGCCGTTTTACAAGCCGGCCGATGACACCCCGGAAATGCGCTATCTGCACGAGCGGCGCAAGGCC
CTGGGCGGTTACCTGCCGCACCGCCGCGTCAAGGCCGACGAGAGCTTTACCGTGCCTGCGCTCGAAACCTTCAAGGCCGT
GCTCGAGCCGACCGCCGAAGGCCGTGAAATTTCCACCACGCAGGCCTACGTGCGCTTCCTCACGCAGCTGCTGCGCGACC
AGGCACTCGGCCCACGCGTGGTGCCCATCCTGGTCGATGAGGCCCGCACCTTCGGCATGGAAGGCCTGTTCCGCCAGGTG
GGCATCTACAACCCTGATGGCCAGAAGTACACGCCGGTCGATAAAGACCAGGTGATGTATTACAAGGAAGACGCCAAGGG
CCAGATCCTGCAAGAGGGCATCAACGAGGCTGGTGGCATGAGCAGCTGGATCGCAGCGGCCACTTCGTACAGCACCAATA
ACAGGATCATGGTCCCGTTCTACGTGTACTACTCGATGTTCGGTTTCCAGCGCATCGGCGACCTGGCCTGGGCGGCTGGC
GACATGCAGGCACGTGGCTTCCTGTTGGGCGGCACCTCTGGCCGGACCACACTGAATGGCGAAGGCCTGCAGCACGAAGA
CGGCCACAGCCACATCCTGGCCGGCACGATTCCCAACTGCATCAGCTACGACCCGACCTTTGCCCATGAGGTGGGTGTCA
TCCTGCACCATGGCTTGAAGCGTATGGTGGAAAAGCAGGACAACGTGTATTTTTACCTCACGCTGCTCAATGAAAACTAT
CCGATGCCAGGCCTCCAGCCCGGTACCGAAGAACAGATCATCAAGGGCATGTACCTCTGCAAGGAAGGCGCCAAGCTCAC
GCCGCGCGTACAACTGCTGGGCTCCGGCACCATCCTGCGTGAATCGATTGCCGCGCAGGAACTGCTTGAGAAAGAGTGGG
GTGTTGCCGCCAACGTGTGGAGCTGCCCGAGCTTCAATGAGTTGGCCCGCGATGGCCAGAACGCCGAACGCTGGAACCTG
CTGCACCCGACCGACAAACCCCGCGTGCCTTTTGTGGGCGAGCAGCTCGACAAGCACGCCGGCCCGGTCGTTGCATCGAC
CGACTACATGAAGGCTTACGCCGAGCAGATCCGGCCGTTTATCCCCAAGGGGCGCACCTACAAGGTCCTGGGCACCGATG
GATTTGGCCGCAGCGACTTCCGCAGCAAGCTGCGCGAGCACTTTGAAATCAACCGCCACTACATCGTGATCGCGGCCCTG
AAGGCGCTCAGCGAAGAGGGTACGGTTCCGGTTGCCAAGGTTGCCGAAGCCATCAAGAAGTACGGTATCAATGCCGACAA
GATCAATCCCCTTTATGCCTGA

Upstream 100 bases:

>100_bases
TTGCGTTTAAAACACGCCTTAGGGACAAGTCAGACACAAGCTTTGTGCGCAGCCTCAAAGTTGTGGTTCGGGTCAAACAA
GCGTTACTCAGGAGACAAAA

Downstream 100 bases:

>100_bases
TGCAGGTTTGATGCATTAGCCCGCAAGCAATCGGAGACAACAACATGGCAGTGGTAGATATTCAGGTTCCTGATATTGGG
GACTTCGACGAAGTGACGGT

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 913; Mature: 912

Protein sequence:

>913_residues
MAANPNEAGADNLRAAANDALGENTLDKDKQETREWMDALSAVIESEGPERAHFLLEQLLEHARQKSIDMPFSANTAYVN
TIETDQEERSPGNLEIEERLRAYMRWNAMAMVVKANRLHPADGGDLGGHIGSFASLASLFGAGFNHFWHAESENHGGDCL
YIQGHVSPGVYARAYLEGRLTEEQLLNFRQEVAGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA
NTENRKVWVFCGDGEMDEVESMGAIGLAAREKLDNLVFVINCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKLIWGSN
WDPLLARDKDGALRKVMIDTLDGDYQAMKANDGAYVRKHFFGQNPKTLEMVSKMSDDDIWNLRRGGHDSQKVYAAFHAAV
NHTGQPTVLLIKTVKGFGMGKIGEGKNTVHQTKKLTDDDIKIFRDRFNIPIPDSQLADLPFYKPADDTPEMRYLHERRKA
LGGYLPHRRVKADESFTVPALETFKAVLEPTAEGREISTTQAYVRFLTQLLRDQALGPRVVPILVDEARTFGMEGLFRQV
GIYNPDGQKYTPVDKDQVMYYKEDAKGQILQEGINEAGGMSSWIAAATSYSTNNRIMVPFYVYYSMFGFQRIGDLAWAAG
DMQARGFLLGGTSGRTTLNGEGLQHEDGHSHILAGTIPNCISYDPTFAHEVGVILHHGLKRMVEKQDNVYFYLTLLNENY
PMPGLQPGTEEQIIKGMYLCKEGAKLTPRVQLLGSGTILRESIAAQELLEKEWGVAANVWSCPSFNELARDGQNAERWNL
LHPTDKPRVPFVGEQLDKHAGPVVASTDYMKAYAEQIRPFIPKGRTYKVLGTDGFGRSDFRSKLREHFEINRHYIVIAAL
KALSEEGTVPVAKVAEAIKKYGINADKINPLYA

Sequences:

>Translated_913_residues
MAANPNEAGADNLRAAANDALGENTLDKDKQETREWMDALSAVIESEGPERAHFLLEQLLEHARQKSIDMPFSANTAYVN
TIETDQEERSPGNLEIEERLRAYMRWNAMAMVVKANRLHPADGGDLGGHIGSFASLASLFGAGFNHFWHAESENHGGDCL
YIQGHVSPGVYARAYLEGRLTEEQLLNFRQEVAGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA
NTENRKVWVFCGDGEMDEVESMGAIGLAAREKLDNLVFVINCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKLIWGSN
WDPLLARDKDGALRKVMIDTLDGDYQAMKANDGAYVRKHFFGQNPKTLEMVSKMSDDDIWNLRRGGHDSQKVYAAFHAAV
NHTGQPTVLLIKTVKGFGMGKIGEGKNTVHQTKKLTDDDIKIFRDRFNIPIPDSQLADLPFYKPADDTPEMRYLHERRKA
LGGYLPHRRVKADESFTVPALETFKAVLEPTAEGREISTTQAYVRFLTQLLRDQALGPRVVPILVDEARTFGMEGLFRQV
GIYNPDGQKYTPVDKDQVMYYKEDAKGQILQEGINEAGGMSSWIAAATSYSTNNRIMVPFYVYYSMFGFQRIGDLAWAAG
DMQARGFLLGGTSGRTTLNGEGLQHEDGHSHILAGTIPNCISYDPTFAHEVGVILHHGLKRMVEKQDNVYFYLTLLNENY
PMPGLQPGTEEQIIKGMYLCKEGAKLTPRVQLLGSGTILRESIAAQELLEKEWGVAANVWSCPSFNELARDGQNAERWNL
LHPTDKPRVPFVGEQLDKHAGPVVASTDYMKAYAEQIRPFIPKGRTYKVLGTDGFGRSDFRSKLREHFEINRHYIVIAAL
KALSEEGTVPVAKVAEAIKKYGINADKINPLYA
>Mature_912_residues
AANPNEAGADNLRAAANDALGENTLDKDKQETREWMDALSAVIESEGPERAHFLLEQLLEHARQKSIDMPFSANTAYVNT
IETDQEERSPGNLEIEERLRAYMRWNAMAMVVKANRLHPADGGDLGGHIGSFASLASLFGAGFNHFWHAESENHGGDCLY
IQGHVSPGVYARAYLEGRLTEEQLLNFRQEVAGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAN
TENRKVWVFCGDGEMDEVESMGAIGLAAREKLDNLVFVINCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKLIWGSNW
DPLLARDKDGALRKVMIDTLDGDYQAMKANDGAYVRKHFFGQNPKTLEMVSKMSDDDIWNLRRGGHDSQKVYAAFHAAVN
HTGQPTVLLIKTVKGFGMGKIGEGKNTVHQTKKLTDDDIKIFRDRFNIPIPDSQLADLPFYKPADDTPEMRYLHERRKAL
GGYLPHRRVKADESFTVPALETFKAVLEPTAEGREISTTQAYVRFLTQLLRDQALGPRVVPILVDEARTFGMEGLFRQVG
IYNPDGQKYTPVDKDQVMYYKEDAKGQILQEGINEAGGMSSWIAAATSYSTNNRIMVPFYVYYSMFGFQRIGDLAWAAGD
MQARGFLLGGTSGRTTLNGEGLQHEDGHSHILAGTIPNCISYDPTFAHEVGVILHHGLKRMVEKQDNVYFYLTLLNENYP
MPGLQPGTEEQIIKGMYLCKEGAKLTPRVQLLGSGTILRESIAAQELLEKEWGVAANVWSCPSFNELARDGQNAERWNLL
HPTDKPRVPFVGEQLDKHAGPVVASTDYMKAYAEQIRPFIPKGRTYKVLGTDGFGRSDFRSKLREHFEINRHYIVIAALK
ALSEEGTVPVAKVAEAIKKYGINADKINPLYA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=891, Percent_Identity=58.8103254769921, Blast_Score=1090, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 102012; Mature: 101881

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANPNEAGADNLRAAANDALGENTLDKDKQETREWMDALSAVIESEGPERAHFLLEQLL
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EHARQKSIDMPFSANTAYVNTIETDQEERSPGNLEIEERLRAYMRWNAMAMVVKANRLHP
HHHHHHCCCCCCCCCCEEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCC
ADGGDLGGHIGSFASLASLFGAGFNHFWHAESENHGGDCLYIQGHVSPGVYARAYLEGRL
CCCCCCCHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEEECCCCCCEEHHHHHCCC
TEEQLLNFRQEVAGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHCCCC
NTENRKVWVFCGDGEMDEVESMGAIGLAAREKLDNLVFVINCNLQRLDGPVRGNGKIIQE
CCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHH
LEGEFRGAGWNVIKLIWGSNWDPLLARDKDGALRKVMIDTLDGDYQAMKANDGAYVRKHF
HHHHHCCCCCEEEEEEECCCCCCCEECCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHH
FGQNPKTLEMVSKMSDDDIWNLRRGGHDSQKVYAAFHAAVNHTGQPTVLLIKTVKGFGMG
CCCCCHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
KIGEGKNTVHQTKKLTDDDIKIFRDRFNIPIPDSQLADLPFYKPADDTPEMRYLHERRKA
CCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LGGYLPHRRVKADESFTVPALETFKAVLEPTAEGREISTTQAYVRFLTQLLRDQALGPRV
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
VPILVDEARTFGMEGLFRQVGIYNPDGQKYTPVDKDQVMYYKEDAKGQILQEGINEAGGM
EEEEECHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCH
SSWIAAATSYSTNNRIMVPFYVYYSMFGFQRIGDLAWAAGDMQARGFLLGGTSGRTTLNG
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEECC
EGLQHEDGHSHILAGTIPNCISYDPTFAHEVGVILHHGLKRMVEKQDNVYFYLTLLNENY
CCCCCCCCCCEEEECCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
PMPGLQPGTEEQIIKGMYLCKEGAKLTPRVQLLGSGTILRESIAAQELLEKEWGVAANVW
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEECCC
SCPSFNELARDGQNAERWNLLHPTDKPRVPFVGEQLDKHAGPVVASTDYMKAYAEQIRPF
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHHHCC
IPKGRTYKVLGTDGFGRSDFRSKLREHFEINRHYIVIAALKALSEEGTVPVAKVAEAIKK
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHH
YGINADKINPLYA
HCCCCCCCCCCCC
>Mature Secondary Structure 
AANPNEAGADNLRAAANDALGENTLDKDKQETREWMDALSAVIESEGPERAHFLLEQLL
CCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EHARQKSIDMPFSANTAYVNTIETDQEERSPGNLEIEERLRAYMRWNAMAMVVKANRLHP
HHHHHHCCCCCCCCCCEEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCC
ADGGDLGGHIGSFASLASLFGAGFNHFWHAESENHGGDCLYIQGHVSPGVYARAYLEGRL
CCCCCCCHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEEECCCCCCEEHHHHHCCC
TEEQLLNFRQEVAGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHCHHHHHHHHHHHHHHHHHHCCCC
NTENRKVWVFCGDGEMDEVESMGAIGLAAREKLDNLVFVINCNLQRLDGPVRGNGKIIQE
CCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHH
LEGEFRGAGWNVIKLIWGSNWDPLLARDKDGALRKVMIDTLDGDYQAMKANDGAYVRKHF
HHHHHCCCCCEEEEEEECCCCCCCEECCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHH
FGQNPKTLEMVSKMSDDDIWNLRRGGHDSQKVYAAFHAAVNHTGQPTVLLIKTVKGFGMG
CCCCCHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
KIGEGKNTVHQTKKLTDDDIKIFRDRFNIPIPDSQLADLPFYKPADDTPEMRYLHERRKA
CCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LGGYLPHRRVKADESFTVPALETFKAVLEPTAEGREISTTQAYVRFLTQLLRDQALGPRV
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
VPILVDEARTFGMEGLFRQVGIYNPDGQKYTPVDKDQVMYYKEDAKGQILQEGINEAGGM
EEEEECHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCH
SSWIAAATSYSTNNRIMVPFYVYYSMFGFQRIGDLAWAAGDMQARGFLLGGTSGRTTLNG
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEECC
EGLQHEDGHSHILAGTIPNCISYDPTFAHEVGVILHHGLKRMVEKQDNVYFYLTLLNENY
CCCCCCCCCCEEEECCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCC
PMPGLQPGTEEQIIKGMYLCKEGAKLTPRVQLLGSGTILRESIAAQELLEKEWGVAANVW
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEECCC
SCPSFNELARDGQNAERWNLLHPTDKPRVPFVGEQLDKHAGPVVASTDYMKAYAEQIRPF
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEECHHHHHHHHHHHHCC
IPKGRTYKVLGTDGFGRSDFRSKLREHFEINRHYIVIAALKALSEEGTVPVAKVAEAIKK
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHH
YGINADKINPLYA
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]