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The map label for this gene is surA [C]

Identifier: 91788447

GI number: 91788447

Start: 2706486

End: 2707271

Strand: Direct

Name: surA [C]

Synonym: Bpro_2585

Alternate gene names: 91788447

Gene position: 2706486-2707271 (Clockwise)

Preceding gene: 91788446

Following gene: 91788449

Centisome position: 52.05

GC content: 57.76

Gene sequence:

>786_bases
ATGAAAAAGCAATTTTTACTGGCTACCGCCGTTGCAGGGCTGCTGGCCATGGGCGCGCAAGGCGCTTTCGCGCAGAACGT
CGCCATCGTCAACGGCAAGGCAGTGCCCAAGGCGCGCCTTGATTCGCTGGCCCAGCAAATTGCCCGCTCCGGCCGTCCGG
TGACCCCCGATATGGAAAACCAGCTGCGCGAAGAAGTCATTGCGCGTGAGGTGTTCATGCAGGAAGCCGAAAAACAGGGG
CTGTCCGGCACCGACGACTTCAAGGTACAGATGGAACTGGCGCGCCAGACCATCCTGATCCGCGAACTGTTCGCGGACTA
TCAAAAGAAAAACCCGGTGACCGATGCTGATTTGAAAGGCGAGTACGACAAATTCGCCGCGGCCAACGGCGGCAAGGAGT
ACAAGGCCCGCCATATCCTGGTCGAGAAGGAAGCCGAGGCCAAGGCCATCATTGCCAGCCTGAAAAAAGGCGGCAAGTTT
GAGGACATCGCGAAGAAACAGTCCAAGGATCCAGGCTCAGGAGCCAAGGGTGGTGACCTCGACTGGGCCAATCCGTCGGG
GTATGTACCTGAGTTCAGCGAAGCGCTGCTCAAGCTCAACAAAGGACAGCTGACCGATGCGCCGGTGAAGTCGCAGTTTG
GCTACCATGTGATCCGCGTGGACGACATCCGCAATGCCCAGCTGCCTTCGTTTGAAGAGGTCAAGCCGCAAATCGCCCAG
CAAATGCAGCAGCAGAAGCTCGCCACCTTCCAGGAAGACCTGCGCAAAAAAGCGAAGATCGAATAA

Upstream 100 bases:

>100_bases
AACCCCGGTGGATGTGCTGTAAAGCCCGTAACCGCCGGCAATCAACTCCGCCCAAGATCCCAACCATTCACCAAGCGTCA
TCAAGGATTACCAACTCATC

Downstream 100 bases:

>100_bases
GCGTCAGTTGACGCTCCGGCGCGTTGTTCGCCATCTAAAAAAAACGCGGCTCAAGGCCGCGTTTTTTTGTTTCACCACAC
CATTACCCGACCCAGCGGCG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKKQFLLATAVAGLLAMGAQGAFAQNVAIVNGKAVPKARLDSLAQQIARSGRPVTPDMENQLREEVIAREVFMQEAEKQG
LSGTDDFKVQMELARQTILIRELFADYQKKNPVTDADLKGEYDKFAAANGGKEYKARHILVEKEAEAKAIIASLKKGGKF
EDIAKKQSKDPGSGAKGGDLDWANPSGYVPEFSEALLKLNKGQLTDAPVKSQFGYHVIRVDDIRNAQLPSFEEVKPQIAQ
QMQQQKLATFQEDLRKKAKIE

Sequences:

>Translated_261_residues
MKKQFLLATAVAGLLAMGAQGAFAQNVAIVNGKAVPKARLDSLAQQIARSGRPVTPDMENQLREEVIAREVFMQEAEKQG
LSGTDDFKVQMELARQTILIRELFADYQKKNPVTDADLKGEYDKFAAANGGKEYKARHILVEKEAEAKAIIASLKKGGKF
EDIAKKQSKDPGSGAKGGDLDWANPSGYVPEFSEALLKLNKGQLTDAPVKSQFGYHVIRVDDIRNAQLPSFEEVKPQIAQ
QMQQQKLATFQEDLRKKAKIE
>Mature_261_residues
MKKQFLLATAVAGLLAMGAQGAFAQNVAIVNGKAVPKARLDSLAQQIARSGRPVTPDMENQLREEVIAREVFMQEAEKQG
LSGTDDFKVQMELARQTILIRELFADYQKKNPVTDADLKGEYDKFAAANGGKEYKARHILVEKEAEAKAIIASLKKGGKF
EDIAKKQSKDPGSGAKGGDLDWANPSGYVPEFSEALLKLNKGQLTDAPVKSQFGYHVIRVDDIRNAQLPSFEEVKPQIAQ
QMQQQKLATFQEDLRKKAKIE

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=98, Percent_Identity=38.7755102040816, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1786238, Length=119, Percent_Identity=42.8571428571429, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786645, Length=137, Percent_Identity=35.7664233576642, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17537235, Length=100, Percent_Identity=41, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28789; Mature: 28789

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQFLLATAVAGLLAMGAQGAFAQNVAIVNGKAVPKARLDSLAQQIARSGRPVTPDMEN
CCCHHHHHHHHHHHHHHCCCCCHHCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
QLREEVIAREVFMQEAEKQGLSGTDDFKVQMELARQTILIRELFADYQKKNPVTDADLKG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EYDKFAAANGGKEYKARHILVEKEAEAKAIIASLKKGGKFEDIAKKQSKDPGSGAKGGDL
CHHHHHHCCCCCHHHHHHEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
DWANPSGYVPEFSEALLKLNKGQLTDAPVKSQFGYHVIRVDDIRNAQLPSFEEVKPQIAQ
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHH
QMQQQKLATFQEDLRKKAKIE
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKQFLLATAVAGLLAMGAQGAFAQNVAIVNGKAVPKARLDSLAQQIARSGRPVTPDMEN
CCCHHHHHHHHHHHHHHCCCCCHHCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
QLREEVIAREVFMQEAEKQGLSGTDDFKVQMELARQTILIRELFADYQKKNPVTDADLKG
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EYDKFAAANGGKEYKARHILVEKEAEAKAIIASLKKGGKFEDIAKKQSKDPGSGAKGGDL
CHHHHHHCCCCCHHHHHHEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
DWANPSGYVPEFSEALLKLNKGQLTDAPVKSQFGYHVIRVDDIRNAQLPSFEEVKPQIAQ
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHH
QMQQQKLATFQEDLRKKAKIE
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]