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The map label for this gene is map [H]

Identifier: 91788449

GI number: 91788449

Start: 2711934

End: 2712788

Strand: Direct

Name: map [H]

Synonym: Bpro_2587

Alternate gene names: 91788449

Gene position: 2711934-2712788 (Clockwise)

Preceding gene: 91788447

Following gene: 91788450

Centisome position: 52.15

GC content: 60.58

Gene sequence:

>855_bases
ATGAGTATTACGTATAAAGATGCTGCGGGCATAGAGGGCATGCGTTTGGCCGGCAGGCTGGCGTCCGAGGTGCTGGACTA
CCTCACGCCCTTCGTCAAACCAGGCGTGACGACCAATGAAATCGACCGGCTGGCCCATGACTACATGACCCAGGTCCAGG
GCACCATTCCCGCGACCCTGGGCTACGGCCCCCCCGGCTACGTGCCCTACCCCAAATCGCTGTGCACCTCGGTCAACCAC
CAAGTGTGCCACGGCATCCCCAACGACAAGCCCCTGAAAAAAGGCGACATCGTCAACATCGATGTGACCGTCATCACCAA
GGACGGCTGGCACGGAGACAACAGCCGCATGTACCTGATCGGCGAAGCGTCGATTGCGGCCAAACGGCTGTGCAAGGTCA
CCTACGAGGCCATGTGGCAGGGCATCATGCGCGTCAAACCGGGTGTGCGTCTGGGTGACATCGGGTTTGCCATCCAGGCC
TATGCAGAAAAACAGGGGTTTTCCGTCGTGCGCGAATTCTGCGGCCACGGCGTCGGCCAGAAGTTCCATGAAGAGCCGCA
GGTGCTGCACTATGGCCGCCCCGGCACGCTGGAAGAACTCAAGCCGGGCATGACGTTCACCATCGAACCCATGATCAATG
CCGGCAAGCGCGATATCAAGGACGGCCCGGAAAAAGACGGCTGGAGCATCGTGACACGAGACCATTCGCTGTCAGCCCAG
TGGGAGCACACCATCCTTGTTTCCGAGACCGGTTACGAGGTGCTGACCGTCTCGGCGGGCAGCCCGGCCATTCCCGCATT
TGTCGCAGACTTTGTTGCCCAAAACAATCCGGCGCAGGTCCTGGTCAGCGCCTGA

Upstream 100 bases:

>100_bases
CCCTCCTTTACCGTTCACTTTGTCTCGCCACATTTCCCCTTCAATTCCGCAAAAATACCCATGCATACCCATGACATGGA
CCAGTGGGATAATCGGAAAT

Downstream 100 bases:

>100_bases
TCCGGTTGCTTTCAGTGCCGTCCTGCGCACCTTGATGCCCCCGCTCCCTACCCATGAGTGAACTGGTTCAGGTGCGGGAG
CAATACCGTGCGGGTAAAAC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSITYKDAAGIEGMRLAGRLASEVLDYLTPFVKPGVTTNEIDRLAHDYMTQVQGTIPATLGYGPPGYVPYPKSLCTSVNH
QVCHGIPNDKPLKKGDIVNIDVTVITKDGWHGDNSRMYLIGEASIAAKRLCKVTYEAMWQGIMRVKPGVRLGDIGFAIQA
YAEKQGFSVVREFCGHGVGQKFHEEPQVLHYGRPGTLEELKPGMTFTIEPMINAGKRDIKDGPEKDGWSIVTRDHSLSAQ
WEHTILVSETGYEVLTVSAGSPAIPAFVADFVAQNNPAQVLVSA

Sequences:

>Translated_284_residues
MSITYKDAAGIEGMRLAGRLASEVLDYLTPFVKPGVTTNEIDRLAHDYMTQVQGTIPATLGYGPPGYVPYPKSLCTSVNH
QVCHGIPNDKPLKKGDIVNIDVTVITKDGWHGDNSRMYLIGEASIAAKRLCKVTYEAMWQGIMRVKPGVRLGDIGFAIQA
YAEKQGFSVVREFCGHGVGQKFHEEPQVLHYGRPGTLEELKPGMTFTIEPMINAGKRDIKDGPEKDGWSIVTRDHSLSAQ
WEHTILVSETGYEVLTVSAGSPAIPAFVADFVAQNNPAQVLVSA
>Mature_283_residues
SITYKDAAGIEGMRLAGRLASEVLDYLTPFVKPGVTTNEIDRLAHDYMTQVQGTIPATLGYGPPGYVPYPKSLCTSVNHQ
VCHGIPNDKPLKKGDIVNIDVTVITKDGWHGDNSRMYLIGEASIAAKRLCKVTYEAMWQGIMRVKPGVRLGDIGFAIQAY
AEKQGFSVVREFCGHGVGQKFHEEPQVLHYGRPGTLEELKPGMTFTIEPMINAGKRDIKDGPEKDGWSIVTRDHSLSAQW
EHTILVSETGYEVLTVSAGSPAIPAFVADFVAQNNPAQVLVSA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=261, Percent_Identity=47.1264367816092, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI40385867, Length=255, Percent_Identity=38.8235294117647, Blast_Score=179, Evalue=3e-45,
Organism=Escherichia coli, GI1786364, Length=270, Percent_Identity=55.1851851851852, Blast_Score=306, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=44.2231075697211, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6323273, Length=257, Percent_Identity=43.1906614785992, Blast_Score=194, Evalue=9e-51,
Organism=Drosophila melanogaster, GI21355531, Length=262, Percent_Identity=44.6564885496183, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24583427, Length=253, Percent_Identity=40.3162055335968, Blast_Score=190, Evalue=8e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30986; Mature: 30855

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITYKDAAGIEGMRLAGRLASEVLDYLTPFVKPGVTTNEIDRLAHDYMTQVQGTIPATL
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEE
GYGPPGYVPYPKSLCTSVNHQVCHGIPNDKPLKKGDIVNIDVTVITKDGWHGDNSRMYLI
CCCCCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEE
GEASIAAKRLCKVTYEAMWQGIMRVKPGVRLGDIGFAIQAYAEKQGFSVVREFCGHGVGQ
ECHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCH
KFHEEPQVLHYGRPGTLEELKPGMTFTIEPMINAGKRDIKDGPEKDGWSIVTRDHSLSAQ
HHCCCCCEEECCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
WEHTILVSETGYEVLTVSAGSPAIPAFVADFVAQNNPAQVLVSA
EEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
SITYKDAAGIEGMRLAGRLASEVLDYLTPFVKPGVTTNEIDRLAHDYMTQVQGTIPATL
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEE
GYGPPGYVPYPKSLCTSVNHQVCHGIPNDKPLKKGDIVNIDVTVITKDGWHGDNSRMYLI
CCCCCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEE
GEASIAAKRLCKVTYEAMWQGIMRVKPGVRLGDIGFAIQAYAEKQGFSVVREFCGHGVGQ
ECHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCCH
KFHEEPQVLHYGRPGTLEELKPGMTFTIEPMINAGKRDIKDGPEKDGWSIVTRDHSLSAQ
HHCCCCCEEECCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCC
WEHTILVSETGYEVLTVSAGSPAIPAFVADFVAQNNPAQVLVSA
EEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]