Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 91788393

GI number: 91788393

Start: 2646098

End: 2647018

Strand: Reverse

Name: appC [H]

Synonym: Bpro_2530

Alternate gene names: 91788393

Gene position: 2647018-2646098 (Counterclockwise)

Preceding gene: 91788394

Following gene: 91788392

Centisome position: 50.9

GC content: 62.11

Gene sequence:

>921_bases
ATGGAAGACCTACCGCAGCGCGCCGCTGTCGAAACACCATTTGTGGAAACGCCTTTTCGGCGTTTCGCACGCAACTTCTT
CAGCAGCAAAATCGCCACGGCTGGTTTCGTCCTGCTGGTGCTGATCGTGCTGGCCGCCAGCTTTGCACCGTGGCTGTCGC
CACAGGATCCGTATGACCTGTCGCGCCTGGACGTGATGGATTCCCGGCTGGAGCCGGGCAAGGCATCGGTCGACGGCCAG
CTCACGTTTTTGCTCGGGACCGACGAGCAGGGCCGCGACATGCTGTCGGCCATTCTTTATGGCATCCGGATTTCGGTGAT
GGTCGGCGTCTCGAGCACCGTGATCGCCTTGCTGCTCGGGTTGACGCTGGGGTTGCTGGCCGGCTATTCGGGCGGGCGCC
TGGAGGCCTTCATCATGCGGATCGCCGATATCCAGCTGTCATTCCCGCCCATCCTGATCGCGCTGATTTTGCTGGCGTTG
ACGGGGCAGGGTGTCGGCAAAATCATCATTGCCCTGGTCGCCGTGCAATGGGCTTACTATGCGCGCACGGCGCGCAGTGC
GGCACTGGTGGAGCGCAAGAAAGAATACATTGAAGCGGCCACAGCTCTCGGCCTGTCGCCGGCCCGCATCATGCTGCGGC
ATTTGCTGCCGAACTGCCTGCCGCCGCTGATCGTCATTGCCGCCCTGCAGGTGGCTTCGGCGATCTCGCTCGAAGCCACC
TTGTCTTTCCTCGGCCTCGGCCTGCCGGTGACCGAGCCATCGCTGGGATTACTGATTGCCAACGGCTTTCAGTACCTGCT
GTCCGGCAAGTACTGGATCAGTTTCTTCCCCGGCATTGCCTTGCTGCTGACGGTGGTGGCGATCAACCTGGTGGCGGACC
AGCTGCGCGATGTGCTGAACCCGCGGCTGCAGACGCAATAA

Upstream 100 bases:

>100_bases
TGCTCATCGTGGTGATTTTCATTGCCATCAATCTGGTGGTCGACGTGGTCTACTCACTGCTCGATCCGCGTGTACGTTTG
TCCGATAGCAAAGGCTGAGC

Downstream 100 bases:

>100_bases
AAACCGCCTGGAAACCGCCATGACGACTTCAACCCAAGCCCGGATACCGCCCCAGATACCGACCCAGATACCGACGCTCA
GCGTCGCCCATCTGAAAACG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MEDLPQRAAVETPFVETPFRRFARNFFSSKIATAGFVLLVLIVLAASFAPWLSPQDPYDLSRLDVMDSRLEPGKASVDGQ
LTFLLGTDEQGRDMLSAILYGIRISVMVGVSSTVIALLLGLTLGLLAGYSGGRLEAFIMRIADIQLSFPPILIALILLAL
TGQGVGKIIIALVAVQWAYYARTARSAALVERKKEYIEAATALGLSPARIMLRHLLPNCLPPLIVIAALQVASAISLEAT
LSFLGLGLPVTEPSLGLLIANGFQYLLSGKYWISFFPGIALLLTVVAINLVADQLRDVLNPRLQTQ

Sequences:

>Translated_306_residues
MEDLPQRAAVETPFVETPFRRFARNFFSSKIATAGFVLLVLIVLAASFAPWLSPQDPYDLSRLDVMDSRLEPGKASVDGQ
LTFLLGTDEQGRDMLSAILYGIRISVMVGVSSTVIALLLGLTLGLLAGYSGGRLEAFIMRIADIQLSFPPILIALILLAL
TGQGVGKIIIALVAVQWAYYARTARSAALVERKKEYIEAATALGLSPARIMLRHLLPNCLPPLIVIAALQVASAISLEAT
LSFLGLGLPVTEPSLGLLIANGFQYLLSGKYWISFFPGIALLLTVVAINLVADQLRDVLNPRLQTQ
>Mature_306_residues
MEDLPQRAAVETPFVETPFRRFARNFFSSKIATAGFVLLVLIVLAASFAPWLSPQDPYDLSRLDVMDSRLEPGKASVDGQ
LTFLLGTDEQGRDMLSAILYGIRISVMVGVSSTVIALLLGLTLGLLAGYSGGRLEAFIMRIADIQLSFPPILIALILLAL
TGQGVGKIIIALVAVQWAYYARTARSAALVERKKEYIEAATALGLSPARIMLRHLLPNCLPPLIVIAALQVASAISLEAT
LSFLGLGLPVTEPSLGLLIANGFQYLLSGKYWISFFPGIALLLTVVAINLVADQLRDVLNPRLQTQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=266, Percent_Identity=40.2255639097744, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789964, Length=304, Percent_Identity=39.1447368421053, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787054, Length=290, Percent_Identity=33.1034482758621, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI1789889, Length=250, Percent_Identity=34.8, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787498, Length=304, Percent_Identity=35.5263157894737, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=32.5688073394495, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787549, Length=277, Percent_Identity=28.8808664259928, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33019; Mature: 33019

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLPQRAAVETPFVETPFRRFARNFFSSKIATAGFVLLVLIVLAASFAPWLSPQDPYDL
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SRLDVMDSRLEPGKASVDGQLTFLLGTDEQGRDMLSAILYGIRISVMVGVSSTVIALLLG
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LTLGLLAGYSGGRLEAFIMRIADIQLSFPPILIALILLALTGQGVGKIIIALVAVQWAYY
HHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARTARSAALVERKKEYIEAATALGLSPARIMLRHLLPNCLPPLIVIAALQVASAISLEAT
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFLGLGLPVTEPSLGLLIANGFQYLLSGKYWISFFPGIALLLTVVAINLVADQLRDVLN
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRLQTQ
CCCCCC
>Mature Secondary Structure
MEDLPQRAAVETPFVETPFRRFARNFFSSKIATAGFVLLVLIVLAASFAPWLSPQDPYDL
CCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SRLDVMDSRLEPGKASVDGQLTFLLGTDEQGRDMLSAILYGIRISVMVGVSSTVIALLLG
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LTLGLLAGYSGGRLEAFIMRIADIQLSFPPILIALILLALTGQGVGKIIIALVAVQWAYY
HHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARTARSAALVERKKEYIEAATALGLSPARIMLRHLLPNCLPPLIVIAALQVASAISLEAT
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFLGLGLPVTEPSLGLLIANGFQYLLSGKYWISFFPGIALLLTVVAINLVADQLRDVLN
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRLQTQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]