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The map label for this gene is cynR [H]

Identifier: 91788345

GI number: 91788345

Start: 2596918

End: 2597829

Strand: Reverse

Name: cynR [H]

Synonym: Bpro_2482

Alternate gene names: 91788345

Gene position: 2597829-2596918 (Counterclockwise)

Preceding gene: 91788351

Following gene: 91788344

Centisome position: 49.96

GC content: 59.32

Gene sequence:

>912_bases
GTGGAACTCAGGCACTTGCGTTATTTCGTGGCTTTGGCTGAATGCCTGAATTTCACCCGCGCCGCAGAACGGGTGCACAT
CACACAATCCACCCTGTCTCACCAGATTCGCCAACTCGAAGAGGAGATTGGGGAGCTCTTGTTTGAGCGGGTGGGCAAAC
GTGTCTTGATCACGGAACGAGGAGAATTGTTTCTCAGCTACGCCGCCAAAGCGCTGAAGGAAGTCGATCAGGGCGTGGCC
GCATTGAAAGAGTCTGCCCGGGGCCTTACAGGCAAATTGCGCATCGGCTCCACACATACGTTCAACCAAGGATTCATTCC
CGAATGCATCGCCACCCTGTTGGTACGGCACCCCACCGTGAAAGTGGCCGCGAGTGAGTTCACTGCTGACGACATAGGAG
AAAGGCTGGCCTCAGGGGCGCTAGATCTGGGGATTTCCTACCGGCCACGCACCGTGGGCGACCTTTGGTTCGAGCCCCTG
TACAACGAGCAAATGGTCTTAGTCGTTTCGCCCCAGCATCCACTCGCCGGTCGGAAGCGAATCCGGTTGGTGGAGCTTCA
TCGGCAGCCTCTGGTATTGCTGCCAGAAGCTTTCGCGACCCGCGCCATGCTCGATGAGTGCTTTCGTGCATGTGATGCCG
AGCCTCTCGTGGTTGTGGAAATGAATACGCTCGCCCCCATGCTGGCACTGGTGGAAAGAACGCAGATCGGCGCCATCGTT
TCCGAAAACGCGGTGCGGGACCGCTCCACGCTGCGCGCAGTCCCACTGGAGAGCCCAACGCCCATGCGTACGCCAGGGAT
CCTCTGGAAGCGCGATGTAGACAAGACGGCGCCGATGCGCGCGTTCGCCTCCATCGTCCGTGCGATTGCACTCAGCAGCA
GATTGCGCCGGCCGTCGGACTCGAACCACTGA

Upstream 100 bases:

>100_bases
AGATGTAGGCGTATTTGACGGCGAATCAACAAAAGATAACAATGATTATTTTCAACAAAAATCATCGATACCATCGATAG
ATTTGGCATCAGGAGAAAAA

Downstream 100 bases:

>100_bases
ATACCTGGATTGATGATCGGTCGAACATCTCACGGACTTGCCTCGAAGGGCGATGACAATACGTTACGCGGCAATGCGTG
GCTGACGATAGACCCGCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Cyn operon transcriptional activator [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MELRHLRYFVALAECLNFTRAAERVHITQSTLSHQIRQLEEEIGELLFERVGKRVLITERGELFLSYAAKALKEVDQGVA
ALKESARGLTGKLRIGSTHTFNQGFIPECIATLLVRHPTVKVAASEFTADDIGERLASGALDLGISYRPRTVGDLWFEPL
YNEQMVLVVSPQHPLAGRKRIRLVELHRQPLVLLPEAFATRAMLDECFRACDAEPLVVVEMNTLAPMLALVERTQIGAIV
SENAVRDRSTLRAVPLESPTPMRTPGILWKRDVDKTAPMRAFASIVRAIALSSRLRRPSDSNH

Sequences:

>Translated_303_residues
MELRHLRYFVALAECLNFTRAAERVHITQSTLSHQIRQLEEEIGELLFERVGKRVLITERGELFLSYAAKALKEVDQGVA
ALKESARGLTGKLRIGSTHTFNQGFIPECIATLLVRHPTVKVAASEFTADDIGERLASGALDLGISYRPRTVGDLWFEPL
YNEQMVLVVSPQHPLAGRKRIRLVELHRQPLVLLPEAFATRAMLDECFRACDAEPLVVVEMNTLAPMLALVERTQIGAIV
SENAVRDRSTLRAVPLESPTPMRTPGILWKRDVDKTAPMRAFASIVRAIALSSRLRRPSDSNH
>Mature_303_residues
MELRHLRYFVALAECLNFTRAAERVHITQSTLSHQIRQLEEEIGELLFERVGKRVLITERGELFLSYAAKALKEVDQGVA
ALKESARGLTGKLRIGSTHTFNQGFIPECIATLLVRHPTVKVAASEFTADDIGERLASGALDLGISYRPRTVGDLWFEPL
YNEQMVLVVSPQHPLAGRKRIRLVELHRQPLVLLPEAFATRAMLDECFRACDAEPLVVVEMNTLAPMLALVERTQIGAIV
SENAVRDRSTLRAVPLESPTPMRTPGILWKRDVDKTAPMRAFASIVRAIALSSRLRRPSDSNH

Specific function: Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR- cynTSX intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=279, Percent_Identity=36.5591397849462, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790399, Length=273, Percent_Identity=30.03663003663, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=30.1038062283737, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787530, Length=221, Percent_Identity=31.6742081447964, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788887, Length=295, Percent_Identity=30.1694915254237, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788748, Length=230, Percent_Identity=28.2608695652174, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=26.4604810996564, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790208, Length=182, Percent_Identity=32.967032967033, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081904, Length=294, Percent_Identity=27.2108843537415, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790262, Length=196, Percent_Identity=30.1020408163265, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367136, Length=232, Percent_Identity=28.8793103448276, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789204, Length=240, Percent_Identity=27.0833333333333, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=25.3968253968254, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787806, Length=292, Percent_Identity=26.3698630136986, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=184, Percent_Identity=27.7173913043478, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788296, Length=198, Percent_Identity=29.7979797979798, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788481, Length=205, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082132, Length=175, Percent_Identity=29.1428571428571, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787589, Length=140, Percent_Identity=31.4285714285714, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789173, Length=169, Percent_Identity=30.1775147928994, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786713, Length=183, Percent_Identity=28.4153005464481, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790783, Length=147, Percent_Identity=27.2108843537415, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788626, Length=213, Percent_Identity=29.5774647887324, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33892; Mature: 33892

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLRYFVALAECLNFTRAAERVHITQSTLSHQIRQLEEEIGELLFERVGKRVLITER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GELFLSYAAKALKEVDQGVAALKESARGLTGKLRIGSTHTFNQGFIPECIATLLVRHPTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCC
KVAASEFTADDIGERLASGALDLGISYRPRTVGDLWFEPLYNEQMVLVVSPQHPLAGRKR
EEHHHHCCHHHHHHHHHCCHHHCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCHH
IRLVELHRQPLVLLPEAFATRAMLDECFRACDAEPLVVVEMNTLAPMLALVERTQIGAIV
EEHEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
SENAVRDRSTLRAVPLESPTPMRTPGILWKRDVDKTAPMRAFASIVRAIALSSRLRRPSD
HHHHHHHHHHHEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SNH
CCC
>Mature Secondary Structure
MELRHLRYFVALAECLNFTRAAERVHITQSTLSHQIRQLEEEIGELLFERVGKRVLITER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
GELFLSYAAKALKEVDQGVAALKESARGLTGKLRIGSTHTFNQGFIPECIATLLVRHPTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCC
KVAASEFTADDIGERLASGALDLGISYRPRTVGDLWFEPLYNEQMVLVVSPQHPLAGRKR
EEHHHHCCHHHHHHHHHCCHHHCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCHH
IRLVELHRQPLVLLPEAFATRAMLDECFRACDAEPLVVVEMNTLAPMLALVERTQIGAIV
EEHEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
SENAVRDRSTLRAVPLESPTPMRTPGILWKRDVDKTAPMRAFASIVRAIALSSRLRRPSD
HHHHHHHHHHHEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
SNH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]