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The map label for this gene is cirA [H]

Identifier: 91788326

GI number: 91788326

Start: 2565916

End: 2567904

Strand: Direct

Name: cirA [H]

Synonym: Bpro_2461

Alternate gene names: 91788326

Gene position: 2565916-2567904 (Clockwise)

Preceding gene: 91788325

Following gene: 91788327

Centisome position: 49.34

GC content: 59.68

Gene sequence:

>1989_bases
ATGAAAAGAGCCGCAGATATCAGAGGCGAGGGAGGCGAGGGAGGCAAATGGCGATGGCGCCGGGCAGCGACGCACGTCAG
CCGTCTGGCTGCCGTAGCATGCGTGACGTTCAAGGTGGGCGCAGTCATCGCGGCAGATGCCACAACGGGGTCCTTGTCCT
CCGTGGATTTTTCACGCATGACGCTTGAAGATCTGGCGAACATCGAGATCTCCTCGGTATTGAAGAGACCCGAGCGGCTG
AGCGATGCGGCTGCGGCGGTCTACGTGATAACGAGCGAAGACATTCGCCGGTCCGGCTATACCAGCATCCCGGAAATACT
GCGCCTTGCACCTAACCTCCAGGTCGCGCGCGAGGACTCAAGCAATTATGCGATTACGGCGCGCGGCTTCAACAGCAGGA
GCGCCAACAAGCTGGAGGTGCTGATAGACGGCCGCAGCGTGTATACGCCGCTGAACTCCGGCGTGTTCTGGGACGTGCAG
GATACCCTGATCGAAGACATAGAACGCATCGAGGTCATCAGCGGACCAGGCGGGACCCTGTGGGGCTCGAATGCCGTCAA
TGGCGTCATCAATATCATCACCCGCTCTTCACGAGATACCCAGGGTACCTTGCTGAGTGGCGGGGGCGGTACCAGGGAGC
GTGGCGCCGGTGCTCGTTATGGCGGCAAGCTGGGCGAGGACACCACGTACCGTCTATATGCAAAGGGCTTTGATCGTGAC
GGCACGCAGACCAACAGTGGCACCGACCTGCAAAATTCGTGGAACATGCAGCAGGCAGGCTTCCGGATTGACTCGGCCCG
CGCCACCGATACCTTTACCCTGCAGGGCGATGCTTACGATGGGTCGATTCATCAACGCACCCTGGCCGATAAGACCATTT
CGGGTGCAAACCTGCTTGGACGCTGGAATCGCGCATTGGCGGATGACGCAAACATCCAGGTCCAGGCCTATTACGACCGG
ACTCAACGCAACTATCCGGGCTCCGCCGGCTTCGGCGAAGTGCTCGATACCTACGACATCGACGTGCAGCATCGTTTCCG
GTGGCGCAAGGACCACGACATTGTGTGGGGCGGCGGCTACCGGCGGGAGCGCGACCATGTCGATAACAGCTTGTTCCTGC
AGTTTCTGCCGAGACAGAAGACACTGAGCCGGGCCAACATCTTTGTCCAGGACAGCATCGCGCTCAGCGAGCGCCTCAAA
TTCACGCTGGGCCTGAAACTGGAGCACAACAACTACACCGGGCTTGAATGGCAACCCAACGCGCGGCTGGCCTGGAAGCT
CAACGATCGCTCGCTGCTGTGGTCGGCTGTCTCGCGGGCGGTGCGCACGCCATCGCGCGTCGACCGCGAATTCTTTGTGC
CGGCTGTCCCGGCCCTGGCTTTCCCGGGATTCATCGGCGGAGACTTTACCTCGGAGAAACTGACCGCCTACGAGATCGGT
TACCGCGCACAACCGACTGCCGATACCTCGTTCTCCGTGTCCACCTTCTACAACGTCTACGATGACCTGCGCAGTCTCGA
ACCCTCCGCGGGTGCCGGGTCACCGCTTGTGATCGCAAACCAGATGGAGGGCAATACCTACGGCGTGGAAATGTGGGGAA
ACTACCGTGTAAACGACTGGTGGCGCTTGAGTGCCGGTTATAACTATCTCAAGAAAGATCTGAGCCTGAAGTCTGGCAGT
AGCGATACCACCAGCCTGGCGGGCTCTGAAACTGATCCGCGACACCAGTTCTCGTTGCGGTCGGCGATGAATCTGGCGCA
CAACGTGGAGCTTGATGTCTCACTGCGCTCGATCGGCACATTGTCCTCCACCCAAGTCCCTCGCTATACCGCGCTCGATG
CGCGCCTGGGCTGGAAGGTTGCCAAAGATGTCGAGGTTTCGTTGACCGCATTCAACCTGCTTGACAAGGGTCATCCGGAG
TTCGGTTCCGGATCGGCGCGCAGTGAGATCGGGCGCAGCTTCTACGCAAAAATGCTATGGAAATTCTGA

Upstream 100 bases:

>100_bases
TCGTACTGAGTCGCCCTGACCAGAGGTTTGAACACCACACTAACCAAGGTCTGGCTGAACGGGGTAACGGATGTTCGAAG
AAAAAGAAAGGAGAGAAATA

Downstream 100 bases:

>100_bases
TCAACATATTGCGCGCTGCAGCGCGCTTGCGCCCAGGCAGCGCCTTGGCTGTTGTGGCATTGGGCATGGTGCTCTTGCCC
GGCAAGGCCAGCGCGGCCGA

Product: TonB-dependent receptor, plug

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MKRAADIRGEGGEGGKWRWRRAATHVSRLAAVACVTFKVGAVIAADATTGSLSSVDFSRMTLEDLANIEISSVLKRPERL
SDAAAAVYVITSEDIRRSGYTSIPEILRLAPNLQVAREDSSNYAITARGFNSRSANKLEVLIDGRSVYTPLNSGVFWDVQ
DTLIEDIERIEVISGPGGTLWGSNAVNGVINIITRSSRDTQGTLLSGGGGTRERGAGARYGGKLGEDTTYRLYAKGFDRD
GTQTNSGTDLQNSWNMQQAGFRIDSARATDTFTLQGDAYDGSIHQRTLADKTISGANLLGRWNRALADDANIQVQAYYDR
TQRNYPGSAGFGEVLDTYDIDVQHRFRWRKDHDIVWGGGYRRERDHVDNSLFLQFLPRQKTLSRANIFVQDSIALSERLK
FTLGLKLEHNNYTGLEWQPNARLAWKLNDRSLLWSAVSRAVRTPSRVDREFFVPAVPALAFPGFIGGDFTSEKLTAYEIG
YRAQPTADTSFSVSTFYNVYDDLRSLEPSAGAGSPLVIANQMEGNTYGVEMWGNYRVNDWWRLSAGYNYLKKDLSLKSGS
SDTTSLAGSETDPRHQFSLRSAMNLAHNVELDVSLRSIGTLSSTQVPRYTALDARLGWKVAKDVEVSLTAFNLLDKGHPE
FGSGSARSEIGRSFYAKMLWKF

Sequences:

>Translated_662_residues
MKRAADIRGEGGEGGKWRWRRAATHVSRLAAVACVTFKVGAVIAADATTGSLSSVDFSRMTLEDLANIEISSVLKRPERL
SDAAAAVYVITSEDIRRSGYTSIPEILRLAPNLQVAREDSSNYAITARGFNSRSANKLEVLIDGRSVYTPLNSGVFWDVQ
DTLIEDIERIEVISGPGGTLWGSNAVNGVINIITRSSRDTQGTLLSGGGGTRERGAGARYGGKLGEDTTYRLYAKGFDRD
GTQTNSGTDLQNSWNMQQAGFRIDSARATDTFTLQGDAYDGSIHQRTLADKTISGANLLGRWNRALADDANIQVQAYYDR
TQRNYPGSAGFGEVLDTYDIDVQHRFRWRKDHDIVWGGGYRRERDHVDNSLFLQFLPRQKTLSRANIFVQDSIALSERLK
FTLGLKLEHNNYTGLEWQPNARLAWKLNDRSLLWSAVSRAVRTPSRVDREFFVPAVPALAFPGFIGGDFTSEKLTAYEIG
YRAQPTADTSFSVSTFYNVYDDLRSLEPSAGAGSPLVIANQMEGNTYGVEMWGNYRVNDWWRLSAGYNYLKKDLSLKSGS
SDTTSLAGSETDPRHQFSLRSAMNLAHNVELDVSLRSIGTLSSTQVPRYTALDARLGWKVAKDVEVSLTAFNLLDKGHPE
FGSGSARSEIGRSFYAKMLWKF
>Mature_662_residues
MKRAADIRGEGGEGGKWRWRRAATHVSRLAAVACVTFKVGAVIAADATTGSLSSVDFSRMTLEDLANIEISSVLKRPERL
SDAAAAVYVITSEDIRRSGYTSIPEILRLAPNLQVAREDSSNYAITARGFNSRSANKLEVLIDGRSVYTPLNSGVFWDVQ
DTLIEDIERIEVISGPGGTLWGSNAVNGVINIITRSSRDTQGTLLSGGGGTRERGAGARYGGKLGEDTTYRLYAKGFDRD
GTQTNSGTDLQNSWNMQQAGFRIDSARATDTFTLQGDAYDGSIHQRTLADKTISGANLLGRWNRALADDANIQVQAYYDR
TQRNYPGSAGFGEVLDTYDIDVQHRFRWRKDHDIVWGGGYRRERDHVDNSLFLQFLPRQKTLSRANIFVQDSIALSERLK
FTLGLKLEHNNYTGLEWQPNARLAWKLNDRSLLWSAVSRAVRTPSRVDREFFVPAVPALAFPGFIGGDFTSEKLTAYEIG
YRAQPTADTSFSVSTFYNVYDDLRSLEPSAGAGSPLVIANQMEGNTYGVEMWGNYRVNDWWRLSAGYNYLKKDLSLKSGS
SDTTSLAGSETDPRHQFSLRSAMNLAHNVELDVSLRSIGTLSSTQVPRYTALDARLGWKVAKDVEVSLTAFNLLDKGHPE
FGSGSARSEIGRSFYAKMLWKF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=682, Percent_Identity=22.1407624633431, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790405, Length=176, Percent_Identity=33.5227272727273, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 73285; Mature: 73285

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAADIRGEGGEGGKWRWRRAATHVSRLAAVACVTFKVGAVIAADATTGSLSSVDFSRM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECEEEEECCCCCCCCCCCHHHH
TLEDLANIEISSVLKRPERLSDAAAAVYVITSEDIRRSGYTSIPEILRLAPNLQVAREDS
HHHHHHCCCHHHHHCCHHHHCCCCEEEEEEECHHHHHCCCCCHHHHHHHCCCCEEEECCC
SNYAITARGFNSRSANKLEVLIDGRSVYTPLNSGVFWDVQDTLIEDIERIEVISGPGGTL
CCEEEEECCCCCCCCCEEEEEECCCEEECCCCCCEEEEHHHHHHHHHHHEEEEECCCCCC
WGSNAVNGVINIITRSSRDTQGTLLSGGGGTRERGAGARYGGKLGEDTTYRLYAKGFDRD
CCCHHHHHHEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GTQTNSGTDLQNSWNMQQAGFRIDSARATDTFTLQGDAYDGSIHQRTLADKTISGANLLG
CCCCCCCCCCCCCCCHHHCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHH
RWNRALADDANIQVQAYYDRTQRNYPGSAGFGEVLDTYDIDVQHRFRWRKDHDIVWGGGY
HHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHCCCCCHHHEECCCCCCEEECCCC
RRERDHVDNSLFLQFLPRQKTLSRANIFVQDSIALSERLKFTLGLKLEHNNYTGLEWQPN
CCHHHHCCCEEEEEECCCHHHHHHCEEEEECCHHHHHCEEEEEEEEEECCCCCCCEECCC
ARLAWKLNDRSLLWSAVSRAVRTPSRVDREFFVPAVPALAFPGFIGGDFTSEKLTAYEIG
CEEEEEECCCHHHHHHHHHHHCCHHHCCHHHCCCCHHHHHCCCCCCCCCCCCCEEEEECC
YRAQPTADTSFSVSTFYNVYDDLRSLEPSAGAGSPLVIANQMEGNTYGVEMWGNYRVNDW
CCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCEECCCE
WRLSAGYNYLKKDLSLKSGSSDTTSLAGSETDPRHQFSLRSAMNLAHNVELDVSLRSIGT
EEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHCCC
LSSTQVPRYTALDARLGWKVAKDVEVSLTAFNLLDKGHPEFGSGSARSEIGRSFYAKMLW
CCCCCCCCEEEECCCCCCEEECCCEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHH
KF
CC
>Mature Secondary Structure
MKRAADIRGEGGEGGKWRWRRAATHVSRLAAVACVTFKVGAVIAADATTGSLSSVDFSRM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECEEEEECCCCCCCCCCCHHHH
TLEDLANIEISSVLKRPERLSDAAAAVYVITSEDIRRSGYTSIPEILRLAPNLQVAREDS
HHHHHHCCCHHHHHCCHHHHCCCCEEEEEEECHHHHHCCCCCHHHHHHHCCCCEEEECCC
SNYAITARGFNSRSANKLEVLIDGRSVYTPLNSGVFWDVQDTLIEDIERIEVISGPGGTL
CCEEEEECCCCCCCCCEEEEEECCCEEECCCCCCEEEEHHHHHHHHHHHEEEEECCCCCC
WGSNAVNGVINIITRSSRDTQGTLLSGGGGTRERGAGARYGGKLGEDTTYRLYAKGFDRD
CCCHHHHHHEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GTQTNSGTDLQNSWNMQQAGFRIDSARATDTFTLQGDAYDGSIHQRTLADKTISGANLLG
CCCCCCCCCCCCCCCHHHCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHH
RWNRALADDANIQVQAYYDRTQRNYPGSAGFGEVLDTYDIDVQHRFRWRKDHDIVWGGGY
HHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHCCCCCHHHEECCCCCCEEECCCC
RRERDHVDNSLFLQFLPRQKTLSRANIFVQDSIALSERLKFTLGLKLEHNNYTGLEWQPN
CCHHHHCCCEEEEEECCCHHHHHHCEEEEECCHHHHHCEEEEEEEEEECCCCCCCEECCC
ARLAWKLNDRSLLWSAVSRAVRTPSRVDREFFVPAVPALAFPGFIGGDFTSEKLTAYEIG
CEEEEEECCCHHHHHHHHHHHCCHHHCCHHHCCCCHHHHHCCCCCCCCCCCCCEEEEECC
YRAQPTADTSFSVSTFYNVYDDLRSLEPSAGAGSPLVIANQMEGNTYGVEMWGNYRVNDW
CCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCEECCCE
WRLSAGYNYLKKDLSLKSGSSDTTSLAGSETDPRHQFSLRSAMNLAHNVELDVSLRSIGT
EEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHCCC
LSSTQVPRYTALDARLGWKVAKDVEVSLTAFNLLDKGHPEFGSGSARSEIGRSFYAKMLW
CCCCCCCCEEEECCCCCCEEECCCEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHH
KF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]