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The map label for this gene is luxQ [H]

Identifier: 91788257

GI number: 91788257

Start: 2484026

End: 2485882

Strand: Reverse

Name: luxQ [H]

Synonym: Bpro_2390

Alternate gene names: 91788257

Gene position: 2485882-2484026 (Counterclockwise)

Preceding gene: 91788258

Following gene: 91788256

Centisome position: 47.8

GC content: 61.28

Gene sequence:

>1857_bases
ATGTGCGCTGGCGCACGGACTTTTCACAGCGCATCTGTAAGACTTCCGGAGTCTTCGAAAGACTTCGCACACCCCCGGCC
AGGACCCTGGAAGCGCCCCCCACAGTCGGCACTTCGCAGGATCGTCGTTACTTTTACAGGAACATGGCCCATGTCACCCA
TTTCAAATCTGAGCGTTCTTGACGCCATTGCCAAAGCCGACGGGATAGAGGTCAAGCGCCAGGAAGCCCTGCTCAAGACC
GGCGCGCTGCAGACCGCCATCCTGACCAGCGAAAATTTCTCCATCATCGCGACCGACGAGAAAGGCATCATCCAGCTCTT
CAACGTCGGCGCCGAGCGCATGCTGGGCTATATGGCGGCCGAAGTCGTCAACAAGATCAACCCCAGCGACATCCATGACC
CGCAGGAAGTGATGGCGCGGGCCCAGGCGCTGAGCGTGGAGCTCGCCACCACCATCACGCCCGGTTTCGAGGCGCTGGCC
TTCAAGGCCTCACGCGGCATTGAGGACATTTACGAGCTGACCTACATCTGCAAGGACGGCAGCCGCTTCCCGGCCATTGT
GTCGATCACCGCCCTGCGTGACGATTTCGGCACCGTCATCGGCTACCTGTTGATCGGCACCGACAACTCAGTGCGCAAGC
AGGTCGAAGTGGCCTTGAAAGAAGCGATGGCGGTGGCCGAAAAGGCCAACCTCGCCAAATCGGATTTTCTGTCCAGCATG
AGCCATGAGCTGCGCACGCCGCTCAGCGCCATCCTTGGCTTTGCGCAATTGATCGAGTCCGGCACGCCGCAGCCCACGCC
GTCGCAAAAGCGCAGCGTGGACCAGATCCTCCAGGCCGGCTGGTACCTGCTGGAGCTGATCAACGAAATCCTGGACCTGG
CGCTGATCGAGTCCGGCAGGCTCTCGCTGTCGCTGGAGCCGGTGTCGCTGGCGGAAGTCATGCTCGAATGCGAAACCCTG
GTCGAATCGCAGGCCGCCAAGCGTGGCATCCGCGTGACTTTTCCGCAGTTTTCCCTGCCCTGCTTCGTCAAGGCCGACCG
CACGCGGCTCAAGCAGGTGTTGATCAACCTGCTGTCCAACGCGATCAAGTACAACACCAGCGGCGGAACGGTGGTGCTCA
AGTGCGTGAACGTTTCGCCCCAACGCATCCGCATTTGCGTGGAAGACACCGGCGAAGGCCTGAATCCGGCCAAAATCGCC
CAGCTCTTCCAGCCCTTCAACCGCCTGGGCCAGGAGGCCAATACCGAACAAGGTACCGGCATTGGCCTGGTGATGACCAA
GCGGCTGATCGAGCTGATGGGCGGCGCCATCGGCGTGGAAAGCATTGTCGGCCAAGGCAGCGTGTTCTGGATCGAGATGG
ACCTCACCGAGGAGCGTGAGCTTCACCCGGTGCTGACAAGCCTGGCGCCGGCACTGCAAAGCCAGGTGCCGACGGATCCC
CGCGCCCACACCCTGCTGTATGTGGAAGACAACCCGGCCAACCTGATGCTGGTGGAAGACCTCATCGCGCGCCGCTCCGA
CATACGGCTGCTGTCGGCCCGGGACGGCATCAGCGGCATCGCGATGGCCAAGGCCTCGCAGCCTGACATCATCCTGATGG
ACATCAACCTGCCGGGCATCAGCGGCATCAAGGCGGTGCAGATTTTGTGCGCGGACCCCTTGACGGCGCATATTCCGGTG
GTGGCGCTCAGCGCCAACGCCATACCCCGCGACATTGAAAAAGGCATGGAGGCCGGCTTCTTCCGCTACCTCACCAAACC
CATCCGGATCAATGAATTCATGGACACCCTGGACCTGGCGCTGAAGTTTTCCAAAACAAAGTCCCCACGCCCTTCCGTAC
CGGAGAAAACCGCATGA

Upstream 100 bases:

>100_bases
CAGCTGGTGCGCCATCAGATTGCGCGCCGGCCCACAAAAACCGCACAGCACCTTGCGGGCGGTCTCATTTCGTTCGCCCG
TGGTATCTTCAGGGCTCGGT

Downstream 100 bases:

>100_bases
ACACCGAATTCGACATTCTGAACGCCAGCATCCTGGTGGTGGACGACCAGGCCGCCAATGTGCAGCTGCTGGAGCAGCTT
CTGAGCAACACCGGCTACAC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MCAGARTFHSASVRLPESSKDFAHPRPGPWKRPPQSALRRIVVTFTGTWPMSPISNLSVLDAIAKADGIEVKRQEALLKT
GALQTAILTSENFSIIATDEKGIIQLFNVGAERMLGYMAAEVVNKINPSDIHDPQEVMARAQALSVELATTITPGFEALA
FKASRGIEDIYELTYICKDGSRFPAIVSITALRDDFGTVIGYLLIGTDNSVRKQVEVALKEAMAVAEKANLAKSDFLSSM
SHELRTPLSAILGFAQLIESGTPQPTPSQKRSVDQILQAGWYLLELINEILDLALIESGRLSLSLEPVSLAEVMLECETL
VESQAAKRGIRVTFPQFSLPCFVKADRTRLKQVLINLLSNAIKYNTSGGTVVLKCVNVSPQRIRICVEDTGEGLNPAKIA
QLFQPFNRLGQEANTEQGTGIGLVMTKRLIELMGGAIGVESIVGQGSVFWIEMDLTEERELHPVLTSLAPALQSQVPTDP
RAHTLLYVEDNPANLMLVEDLIARRSDIRLLSARDGISGIAMAKASQPDIILMDINLPGISGIKAVQILCADPLTAHIPV
VALSANAIPRDIEKGMEAGFFRYLTKPIRINEFMDTLDLALKFSKTKSPRPSVPEKTA

Sequences:

>Translated_618_residues
MCAGARTFHSASVRLPESSKDFAHPRPGPWKRPPQSALRRIVVTFTGTWPMSPISNLSVLDAIAKADGIEVKRQEALLKT
GALQTAILTSENFSIIATDEKGIIQLFNVGAERMLGYMAAEVVNKINPSDIHDPQEVMARAQALSVELATTITPGFEALA
FKASRGIEDIYELTYICKDGSRFPAIVSITALRDDFGTVIGYLLIGTDNSVRKQVEVALKEAMAVAEKANLAKSDFLSSM
SHELRTPLSAILGFAQLIESGTPQPTPSQKRSVDQILQAGWYLLELINEILDLALIESGRLSLSLEPVSLAEVMLECETL
VESQAAKRGIRVTFPQFSLPCFVKADRTRLKQVLINLLSNAIKYNTSGGTVVLKCVNVSPQRIRICVEDTGEGLNPAKIA
QLFQPFNRLGQEANTEQGTGIGLVMTKRLIELMGGAIGVESIVGQGSVFWIEMDLTEERELHPVLTSLAPALQSQVPTDP
RAHTLLYVEDNPANLMLVEDLIARRSDIRLLSARDGISGIAMAKASQPDIILMDINLPGISGIKAVQILCADPLTAHIPV
VALSANAIPRDIEKGMEAGFFRYLTKPIRINEFMDTLDLALKFSKTKSPRPSVPEKTA
>Mature_618_residues
MCAGARTFHSASVRLPESSKDFAHPRPGPWKRPPQSALRRIVVTFTGTWPMSPISNLSVLDAIAKADGIEVKRQEALLKT
GALQTAILTSENFSIIATDEKGIIQLFNVGAERMLGYMAAEVVNKINPSDIHDPQEVMARAQALSVELATTITPGFEALA
FKASRGIEDIYELTYICKDGSRFPAIVSITALRDDFGTVIGYLLIGTDNSVRKQVEVALKEAMAVAEKANLAKSDFLSSM
SHELRTPLSAILGFAQLIESGTPQPTPSQKRSVDQILQAGWYLLELINEILDLALIESGRLSLSLEPVSLAEVMLECETL
VESQAAKRGIRVTFPQFSLPCFVKADRTRLKQVLINLLSNAIKYNTSGGTVVLKCVNVSPQRIRICVEDTGEGLNPAKIA
QLFQPFNRLGQEANTEQGTGIGLVMTKRLIELMGGAIGVESIVGQGSVFWIEMDLTEERELHPVLTSLAPALQSQVPTDP
RAHTLLYVEDNPANLMLVEDLIARRSDIRLLSARDGISGIAMAKASQPDIILMDINLPGISGIKAVQILCADPLTAHIPV
VALSANAIPRDIEKGMEAGFFRYLTKPIRINEFMDTLDLALKFSKTKSPRPSVPEKTA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=452, Percent_Identity=30.0884955752212, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=30.9711286089239, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081816, Length=377, Percent_Identity=32.6259946949602, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1789149, Length=292, Percent_Identity=32.1917808219178, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=36.5758754863813, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=26.984126984127, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788393, Length=214, Percent_Identity=29.4392523364486, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.3913043478261, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=27.9835390946502, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786783, Length=245, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=26.3392857142857, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=26.1261261261261, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=28.7610619469027, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=296, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=25, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67273; Mature: 67273

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAGARTFHSASVRLPESSKDFAHPRPGPWKRPPQSALRRIVVTFTGTWPMSPISNLSVL
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHCEEEEEEECCCCCCCCCCHHHH
DAIAKADGIEVKRQEALLKTGALQTAILTSENFSIIATDEKGIIQLFNVGAERMLGYMAA
HHHHHCCCCCHHHHHHHHHHCCHHEEEEECCCCEEEEECCCCHHHHHHHCHHHHHHHHHH
EVVNKINPSDIHDPQEVMARAQALSVELATTITPGFEALAFKASRGIEDIYELTYICKDG
HHHHCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCC
SRFPAIVSITALRDDFGTVIGYLLIGTDNSVRKQVEVALKEAMAVAEKANLAKSDFLSSM
CCCCEEEEEEHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPLSAILGFAQLIESGTPQPTPSQKRSVDQILQAGWYLLELINEILDLALIESGR
HHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSLSLEPVSLAEVMLECETLVESQAAKRGIRVTFPQFSLPCFVKADRTRLKQVLINLLSN
EEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHH
AIKYNTSGGTVVLKCVNVSPQRIRICVEDTGEGLNPAKIAQLFQPFNRLGQEANTEQGTG
HHEECCCCCEEEEEEECCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
IGLVMTKRLIELMGGAIGVESIVGQGSVFWIEMDLTEERELHPVLTSLAPALQSQVPTDP
CHHHHHHHHHHHHCCHHCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
RAHTLLYVEDNPANLMLVEDLIARRSDIRLLSARDGISGIAMAKASQPDIILMDINLPGI
CCEEEEEEECCCCCEEEHHHHHCCCCCCEEEECCCCCCCEEEECCCCCCEEEEEECCCCC
SGIKAVQILCADPLTAHIPVVALSANAIPRDIEKGMEAGFFRYLTKPIRINEFMDTLDLA
CCHHHEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LKFSKTKSPRPSVPEKTA
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCAGARTFHSASVRLPESSKDFAHPRPGPWKRPPQSALRRIVVTFTGTWPMSPISNLSVL
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHCEEEEEEECCCCCCCCCCHHHH
DAIAKADGIEVKRQEALLKTGALQTAILTSENFSIIATDEKGIIQLFNVGAERMLGYMAA
HHHHHCCCCCHHHHHHHHHHCCHHEEEEECCCCEEEEECCCCHHHHHHHCHHHHHHHHHH
EVVNKINPSDIHDPQEVMARAQALSVELATTITPGFEALAFKASRGIEDIYELTYICKDG
HHHHCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCC
SRFPAIVSITALRDDFGTVIGYLLIGTDNSVRKQVEVALKEAMAVAEKANLAKSDFLSSM
CCCCEEEEEEHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPLSAILGFAQLIESGTPQPTPSQKRSVDQILQAGWYLLELINEILDLALIESGR
HHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSLSLEPVSLAEVMLECETLVESQAAKRGIRVTFPQFSLPCFVKADRTRLKQVLINLLSN
EEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHH
AIKYNTSGGTVVLKCVNVSPQRIRICVEDTGEGLNPAKIAQLFQPFNRLGQEANTEQGTG
HHEECCCCCEEEEEEECCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
IGLVMTKRLIELMGGAIGVESIVGQGSVFWIEMDLTEERELHPVLTSLAPALQSQVPTDP
CHHHHHHHHHHHHCCHHCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
RAHTLLYVEDNPANLMLVEDLIARRSDIRLLSARDGISGIAMAKASQPDIILMDINLPGI
CCEEEEEEECCCCCEEEHHHHHCCCCCCEEEECCCCCCCEEEECCCCCCEEEEEECCCCC
SGIKAVQILCADPLTAHIPVVALSANAIPRDIEKGMEAGFFRYLTKPIRINEFMDTLDLA
CCHHHEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LKFSKTKSPRPSVPEKTA
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]