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The map label for this gene is 91788258

Identifier: 91788258

GI number: 91788258

Start: 2486043

End: 2487401

Strand: Reverse

Name: 91788258

Synonym: Bpro_2391

Alternate gene names: NA

Gene position: 2487401-2486043 (Counterclockwise)

Preceding gene: 91788259

Following gene: 91788257

Centisome position: 47.83

GC content: 65.56

Gene sequence:

>1359_bases
ATGAACCCGCATCCAACCCAGCACAGTCCCCGCGACACCGCAGTGCGCGAAGGACTGCGCCGGCACCTTCTGCCACTGGA
AGACGGTGCCGGCGCCCATGACCCCCTGATGCGGCTGATCGGACAGGCCCGCTTCGCCCTCCTCGGTGAAGCCTCCCACG
GTACGCAGGAGTTCTACCGCGAACGGGCCGAGATCACCAAACGGCTGATCACCGAAAAGAGCTTTAACGCCGTGGTCGTC
GAAGGCGACTGGCCCGACGCACTGCGCGTTAACCGTTATGTGCGCGGCCTGTCGGATGACAAGGACGCGGTGGCCGCACT
GTCGGGCTTCCAGCGGTTTCCGGCCTGGATGTGGCGCAATACGGTGGTGGTTGATTTCGTTGAATGGCTGCGTGACCACA
ACAGCGGTCTGGCACCCAGGCAGCAGACCGGCTTTTACGGTCTGGACCTCTACAGCCTGTTCAGCTCCATTCAGGCGGTG
CTCGCTTACCTCGACCAGGCAGATCCTGAAGCGGCACGCCGCGCCCGCTACCGTTATGCCTGCCTCGACCATGCGGCAGA
AGACAGCCAGGCCTACGGCTACGCAGCCGCCTTTGGCCTGGGAGCGAGCTGCGAGGACGAGGTGGTGCAGCAGCTGCGCG
ACATGAATCGCCGCGCCGGTGAGTTTTCACCGGTCAACGGGCTGGAGTGGGACGAGGCTTTCTTTGCCCAGCAGAACGCA
CGCCTGGTACGCAACGCCGAAGAGTACTACCGCACCATGTTTCACGGCCGGGTCTCCTCCTGGAATCTGCGCGACAGCCA
CATGGTGGAGACGCTCCAGGCGCTGGACCGCCACCTGACCGCCAACGGCCCGCCGCCGCGTATTGCGGTCTGGGCGCACA
ACTCCCACCTGGGCGATGCCTCGGCCACCCAGATGGGCGAACGGGGCGAATGGAATGTGGGCCAGCTCATGCGCGACCGC
TACGCGGGCGACGCCGTGCTGGTGGGCTTCAGCACCCATCATGGCTGGGTCACGGCCGCATCGGATTGGGGTGAAGCCGC
ACACCGCAAGCGGGTGCGTCCGGGTCAGCCCGGCAGCTGGGAGGACATGTTTCACCAGACGGGCTCGGCCCGCTTCATGC
TGGCGCTGCGTGACAACGCGGCCCTGCGCCCCCTGCTGGCGCCGCTGCGGCTGCAACGGGCCATCGGCGTGATCTACCGA
CCCGAAACGGAACGCCACAGCCACTACTTTCACACCCACCTGGCCAGCCAGTTTGATGCGGTAATCCATCTGGACGAGAC
CAGCGCGCTGGAGCCGCTGGACAAAGGCCCGGTCTGGAACACGGGCGAAGCGCCAGAGACCTTCCCCTCTGGTATCTAA

Upstream 100 bases:

>100_bases
CCTGCTGCTGAAAAAGGCCCGGCAGGAACACCCCCCGGGCAACCCGATCGTCAGCCCGTCTTCCGGCCATTGAGCATCCC
CCGCAAAAGAGCGCTCCACC

Downstream 100 bases:

>100_bases
TCCCGGCGTCTAATCCCGGCTGAAAGCGCCCAGCCACCCAAGCAACGGCGTCAGGTCTTCCAGCTGGTGCGCCATCAGAT
TGCGCGCCGGCCCACAAAAA

Product: erythromycin esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNPHPTQHSPRDTAVREGLRRHLLPLEDGAGAHDPLMRLIGQARFALLGEASHGTQEFYRERAEITKRLITEKSFNAVVV
EGDWPDALRVNRYVRGLSDDKDAVAALSGFQRFPAWMWRNTVVVDFVEWLRDHNSGLAPRQQTGFYGLDLYSLFSSIQAV
LAYLDQADPEAARRARYRYACLDHAAEDSQAYGYAAAFGLGASCEDEVVQQLRDMNRRAGEFSPVNGLEWDEAFFAQQNA
RLVRNAEEYYRTMFHGRVSSWNLRDSHMVETLQALDRHLTANGPPPRIAVWAHNSHLGDASATQMGERGEWNVGQLMRDR
YAGDAVLVGFSTHHGWVTAASDWGEAAHRKRVRPGQPGSWEDMFHQTGSARFMLALRDNAALRPLLAPLRLQRAIGVIYR
PETERHSHYFHTHLASQFDAVIHLDETSALEPLDKGPVWNTGEAPETFPSGI

Sequences:

>Translated_452_residues
MNPHPTQHSPRDTAVREGLRRHLLPLEDGAGAHDPLMRLIGQARFALLGEASHGTQEFYRERAEITKRLITEKSFNAVVV
EGDWPDALRVNRYVRGLSDDKDAVAALSGFQRFPAWMWRNTVVVDFVEWLRDHNSGLAPRQQTGFYGLDLYSLFSSIQAV
LAYLDQADPEAARRARYRYACLDHAAEDSQAYGYAAAFGLGASCEDEVVQQLRDMNRRAGEFSPVNGLEWDEAFFAQQNA
RLVRNAEEYYRTMFHGRVSSWNLRDSHMVETLQALDRHLTANGPPPRIAVWAHNSHLGDASATQMGERGEWNVGQLMRDR
YAGDAVLVGFSTHHGWVTAASDWGEAAHRKRVRPGQPGSWEDMFHQTGSARFMLALRDNAALRPLLAPLRLQRAIGVIYR
PETERHSHYFHTHLASQFDAVIHLDETSALEPLDKGPVWNTGEAPETFPSGI
>Mature_452_residues
MNPHPTQHSPRDTAVREGLRRHLLPLEDGAGAHDPLMRLIGQARFALLGEASHGTQEFYRERAEITKRLITEKSFNAVVV
EGDWPDALRVNRYVRGLSDDKDAVAALSGFQRFPAWMWRNTVVVDFVEWLRDHNSGLAPRQQTGFYGLDLYSLFSSIQAV
LAYLDQADPEAARRARYRYACLDHAAEDSQAYGYAAAFGLGASCEDEVVQQLRDMNRRAGEFSPVNGLEWDEAFFAQQNA
RLVRNAEEYYRTMFHGRVSSWNLRDSHMVETLQALDRHLTANGPPPRIAVWAHNSHLGDASATQMGERGEWNVGQLMRDR
YAGDAVLVGFSTHHGWVTAASDWGEAAHRKRVRPGQPGSWEDMFHQTGSARFMLALRDNAALRPLLAPLRLQRAIGVIYR
PETERHSHYFHTHLASQFDAVIHLDETSALEPLDKGPVWNTGEAPETFPSGI

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007815
- InterPro:   IPR000836 [H]

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 50976; Mature: 50976

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]