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The map label for this gene is ahpC [C]

Identifier: 91788241

GI number: 91788241

Start: 2468333

End: 2468983

Strand: Direct

Name: ahpC [C]

Synonym: Bpro_2374

Alternate gene names: 91788241

Gene position: 2468333-2468983 (Clockwise)

Preceding gene: 91788240

Following gene: 91788242

Centisome position: 47.47

GC content: 60.22

Gene sequence:

>651_bases
ATGGCAACTCTCAGACTCGGCGACATCGCCCCTGACTTCACACAAGACTCCACGGAAGGGAAGATTTCCTTTCACGCGTG
GGCGGGCGACTCCTGGGTTGTGCTGTTTTCCCATCCCGCTGACTTCACGCCGGTATGCACCACCGAACTGGGCAAAACCG
CCGCTCTGAGCCGCGAATTTGCCAAACGCCATGTCAAACCCATCGCCATCAGCGTGGACCCGCTGGAGTCGCATGGCAAG
TGGGTGCATGACATCAACGAAACGCAAAACACCACGGTGAACTTCCCCATCCTGGCCGATGCCGACCGCAAGGTGGCCAA
CCTGTACGACATGATTCACCCGAACGCCTTGAGCACCGGCCCCACGGCCACGGTGCGCAGCGTGTTCATCATCGACCCGA
AAAAGGTGATTCGCACCACCTTCACGTACCCCGCCAGCACCGGCCGCAATTTCGACGAGATCCTGCGCGTCATTGACTCG
CTGCAGCTGACCGACGGCTACAAGGTGGCCACGCCCGTGAACTGGAAAGACGGCGACGATGTGATCATCGTGCCCAGCCT
GCAGGATCCGGCCGAGCTGGCCCAGCGTTTTCCCAAGGGATTCAAGGCCGTCAAGCCTTACCTGCGCATCACACCGCAGC
CCAACAAGTAA

Upstream 100 bases:

>100_bases
TGTGTAAATGAAGATAATTTAAGAGAAATATATTCTTTTGAGTTTTAAGGTCCGGTCCCCACAATGCCTTTCGACAACAC
AAATTGCAAAGGACCAGACC

Downstream 100 bases:

>100_bases
ATGGCCCCCACGCTTTTCGCTTTGCGTAATGCGCTGCCCCCCGAGGGGGCCGCTGCGCCTGCGGCCCGGCAAAGCCGGTT
CCGCGGCCCCGGCTTGCAAA

Product: 1-Cys peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MATLRLGDIAPDFTQDSTEGKISFHAWAGDSWVVLFSHPADFTPVCTTELGKTAALSREFAKRHVKPIAISVDPLESHGK
WVHDINETQNTTVNFPILADADRKVANLYDMIHPNALSTGPTATVRSVFIIDPKKVIRTTFTYPASTGRNFDEILRVIDS
LQLTDGYKVATPVNWKDGDDVIIVPSLQDPAELAQRFPKGFKAVKPYLRITPQPNK

Sequences:

>Translated_216_residues
MATLRLGDIAPDFTQDSTEGKISFHAWAGDSWVVLFSHPADFTPVCTTELGKTAALSREFAKRHVKPIAISVDPLESHGK
WVHDINETQNTTVNFPILADADRKVANLYDMIHPNALSTGPTATVRSVFIIDPKKVIRTTFTYPASTGRNFDEILRVIDS
LQLTDGYKVATPVNWKDGDDVIIVPSLQDPAELAQRFPKGFKAVKPYLRITPQPNK
>Mature_215_residues
ATLRLGDIAPDFTQDSTEGKISFHAWAGDSWVVLFSHPADFTPVCTTELGKTAALSREFAKRHVKPIAISVDPLESHGKW
VHDINETQNTTVNFPILADADRKVANLYDMIHPNALSTGPTATVRSVFIIDPKKVIRTTFTYPASTGRNFDEILRVIDSL
QLTDGYKVATPVNWKDGDDVIIVPSLQDPAELAQRFPKGFKAVKPYLRITPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=51.3513513513513, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI32189392, Length=193, Percent_Identity=32.6424870466321, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI4505591, Length=194, Percent_Identity=31.4432989690722, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI32455266, Length=194, Percent_Identity=31.4432989690722, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI32455264, Length=194, Percent_Identity=31.4432989690722, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI5453549, Length=169, Percent_Identity=29.585798816568, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI32483377, Length=189, Percent_Identity=29.1005291005291, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5802974, Length=169, Percent_Identity=30.1775147928994, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786822, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=222, Percent_Identity=42.3423423423423, Blast_Score=168, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=201, Percent_Identity=28.8557213930348, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32565831, Length=201, Percent_Identity=28.8557213930348, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17554494, Length=169, Percent_Identity=28.9940828402367, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=54.2452830188679, Blast_Score=218, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6323613, Length=188, Percent_Identity=30.3191489361702, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=188, Percent_Identity=29.2553191489362, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581278, Length=218, Percent_Identity=49.0825688073394, Blast_Score=216, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=51.4563106796116, Blast_Score=190, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=50.9708737864078, Blast_Score=190, Evalue=7e-49,
Organism=Drosophila melanogaster, GI17975518, Length=206, Percent_Identity=50.9708737864078, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17738015, Length=180, Percent_Identity=29.4444444444444, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17157991, Length=167, Percent_Identity=31.7365269461078, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24641739, Length=167, Percent_Identity=31.7365269461078, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=30.2197802197802, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24656348, Length=180, Percent_Identity=30, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864676, Length=180, Percent_Identity=30, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23955; Mature: 23824

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLRLGDIAPDFTQDSTEGKISFHAWAGDSWVVLFSHPADFTPVCTTELGKTAALSREF
CCEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHCCHHHHHHHHH
AKRHVKPIAISVDPLESHGKWVHDINETQNTTVNFPILADADRKVANLYDMIHPNALSTG
HHHCCCEEEEEECCCHHCCCEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCC
PTATVRSVFIIDPKKVIRTTFTYPASTGRNFDEILRVIDSLQLTDGYKVATPVNWKDGDD
CCCEEEEEEEECCHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
VIIVPSLQDPAELAQRFPKGFKAVKPYLRITPQPNK
EEEEECCCCHHHHHHHCCCHHHHHCCEEEECCCCCC
>Mature Secondary Structure 
ATLRLGDIAPDFTQDSTEGKISFHAWAGDSWVVLFSHPADFTPVCTTELGKTAALSREF
CEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHCCHHHHHHHHH
AKRHVKPIAISVDPLESHGKWVHDINETQNTTVNFPILADADRKVANLYDMIHPNALSTG
HHHCCCEEEEEECCCHHCCCEEECCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCC
PTATVRSVFIIDPKKVIRTTFTYPASTGRNFDEILRVIDSLQLTDGYKVATPVNWKDGDD
CCCEEEEEEEECCHHHHHEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
VIIVPSLQDPAELAQRFPKGFKAVKPYLRITPQPNK
EEEEECCCCHHHHHHHCCCHHHHHCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]