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The map label for this gene is aaeR [H]

Identifier: 91788240

GI number: 91788240

Start: 2467261

End: 2468166

Strand: Direct

Name: aaeR [H]

Synonym: Bpro_2373

Alternate gene names: 91788240

Gene position: 2467261-2468166 (Clockwise)

Preceding gene: 91788238

Following gene: 91788241

Centisome position: 47.44

GC content: 65.23

Gene sequence:

>906_bases
ATGCAGGACCTGAACGACATGCTGTACTTTGCCGAGGTAGCGGAGCGGGGCGGTTTTGCCGCCGCCGGGCGCTCGCTGGG
CCTGCCCAAATCGCGTCTGTCGCGCCGGGTGGCTGAGCTGGAGGCAAGGCTCGGCGTGCGACTGTTGCAGCGGACCACCC
GCAAGCTCTCGCTGACGGAGATTGGCGAGATCTACCTGCGCCACTGCAGTGCCATGCGGGATGAAGCCCTGGCGGCCGCC
GAAGCCGTGGCGCAGGTACAGGTGGAGCCTCGCGGCACCTTGCGCATCACCTGTCCGGTGACGCTGGCGCAAAGCACGCT
CGGCTACCTGGTGCCGCGCTTCATGGCGCTGCATCCCCAAGTCAAGGTCGACATGCGCGTGACCAACCGCGTGGTGGACC
TGGTGGAAGAGGGCATAGACATTGCGCTGCGCGTGCGGCCCACGCTGGAAGACAGTGGTAGCCTGGTAGTGAAAAACCTG
GGCTCGAGCGGCGGCGAATTGCTGGCCAGCCCAACGCTGTTGGCCCGTCAGGGCCGGCCCGAAAAGCCGGAAGACCTGAT
GAAGCTGGACACCGTGGCCATGTCGTGGGTGGACGGCCGTTCATCCTGGACGCTGCTGGGCCCCGAGGGACAGGAGTTTG
TGTTGCAGCACCAGCCGCGCTATGTGGCTGACGACTTGCAGACGCTCAAGCTGGCCGTGCTGGCGGGTACGGGCATAAGC
TTTTTACCCAATTCGCTCAGCGCCGCAGAGCAGCAGGCCCAGTTGCTGGTGCCCGTGCTGCCCGGCTGGGCACCCAAACC
CGGCGTAGCTCATGCCGTGTTTCCGTCGCGGCGAGGGCAGGTGCCTGCGGTGCGAAGTTTTCTGGATTATCTGGGGGAAC
GGATGAGGGGTGAGAGTCTGGTTTAA

Upstream 100 bases:

>100_bases
TGGATAGATTGTGCTGGTGCATCGATTGTTTGATAAGTCGGCAAAATTGCGATAGATTGTCCTATTCATGTAGCGAATCC
AAGAAAACGGAGAATTTCCC

Downstream 100 bases:

>100_bases
GGCTCAGGGCTTGGGCTCTTCTTAGGCTGGCTGGCCGGGGGTGCCCGAAAATCCAGACCATCGTTATGTGTAAATGAAGA
TAATTTAAGAGAAATATATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MQDLNDMLYFAEVAERGGFAAAGRSLGLPKSRLSRRVAELEARLGVRLLQRTTRKLSLTEIGEIYLRHCSAMRDEALAAA
EAVAQVQVEPRGTLRITCPVTLAQSTLGYLVPRFMALHPQVKVDMRVTNRVVDLVEEGIDIALRVRPTLEDSGSLVVKNL
GSSGGELLASPTLLARQGRPEKPEDLMKLDTVAMSWVDGRSSWTLLGPEGQEFVLQHQPRYVADDLQTLKLAVLAGTGIS
FLPNSLSAAEQQAQLLVPVLPGWAPKPGVAHAVFPSRRGQVPAVRSFLDYLGERMRGESLV

Sequences:

>Translated_301_residues
MQDLNDMLYFAEVAERGGFAAAGRSLGLPKSRLSRRVAELEARLGVRLLQRTTRKLSLTEIGEIYLRHCSAMRDEALAAA
EAVAQVQVEPRGTLRITCPVTLAQSTLGYLVPRFMALHPQVKVDMRVTNRVVDLVEEGIDIALRVRPTLEDSGSLVVKNL
GSSGGELLASPTLLARQGRPEKPEDLMKLDTVAMSWVDGRSSWTLLGPEGQEFVLQHQPRYVADDLQTLKLAVLAGTGIS
FLPNSLSAAEQQAQLLVPVLPGWAPKPGVAHAVFPSRRGQVPAVRSFLDYLGERMRGESLV
>Mature_301_residues
MQDLNDMLYFAEVAERGGFAAAGRSLGLPKSRLSRRVAELEARLGVRLLQRTTRKLSLTEIGEIYLRHCSAMRDEALAAA
EAVAQVQVEPRGTLRITCPVTLAQSTLGYLVPRFMALHPQVKVDMRVTNRVVDLVEEGIDIALRVRPTLEDSGSLVVKNL
GSSGGELLASPTLLARQGRPEKPEDLMKLDTVAMSWVDGRSSWTLLGPEGQEFVLQHQPRYVADDLQTLKLAVLAGTGIS
FLPNSLSAAEQQAQLLVPVLPGWAPKPGVAHAVFPSRRGQVPAVRSFLDYLGERMRGESLV

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=302, Percent_Identity=33.112582781457, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=32.5503355704698, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=29.1095890410959, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=29.6551724137931, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693193, Length=303, Percent_Identity=29.042904290429, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=25.4295532646048, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789440, Length=188, Percent_Identity=25.531914893617, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=32.03125, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=142, Percent_Identity=30.2816901408451, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=149, Percent_Identity=30.8724832214765, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32867; Mature: 32867

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLNDMLYFAEVAERGGFAAAGRSLGLPKSRLSRRVAELEARLGVRLLQRTTRKLSLTE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IGEIYLRHCSAMRDEALAAAEAVAQVQVEPRGTLRITCPVTLAQSTLGYLVPRFMALHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHCCC
VKVDMRVTNRVVDLVEEGIDIALRVRPTLEDSGSLVVKNLGSSGGELLASPTLLARQGRP
EEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCC
EKPEDLMKLDTVAMSWVDGRSSWTLLGPEGQEFVLQHQPRYVADDLQTLKLAVLAGTGIS
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHH
FLPNSLSAAEQQAQLLVPVLPGWAPKPGVAHAVFPSRRGQVPAVRSFLDYLGERMRGESL
HCCCHHHHHHHHHHEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCC
V
C
>Mature Secondary Structure
MQDLNDMLYFAEVAERGGFAAAGRSLGLPKSRLSRRVAELEARLGVRLLQRTTRKLSLTE
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IGEIYLRHCSAMRDEALAAAEAVAQVQVEPRGTLRITCPVTLAQSTLGYLVPRFMALHPQ
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHCCC
VKVDMRVTNRVVDLVEEGIDIALRVRPTLEDSGSLVVKNLGSSGGELLASPTLLARQGRP
EEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCC
EKPEDLMKLDTVAMSWVDGRSSWTLLGPEGQEFVLQHQPRYVADDLQTLKLAVLAGTGIS
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHH
FLPNSLSAAEQQAQLLVPVLPGWAPKPGVAHAVFPSRRGQVPAVRSFLDYLGERMRGESL
HCCCHHHHHHHHHHEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]