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The map label for this gene is siaT [H]

Identifier: 91788079

GI number: 91788079

Start: 2302973

End: 2304271

Strand: Reverse

Name: siaT [H]

Synonym: Bpro_2206

Alternate gene names: 91788079

Gene position: 2304271-2302973 (Counterclockwise)

Preceding gene: 91788080

Following gene: 91788078

Centisome position: 44.31

GC content: 61.28

Gene sequence:

>1299_bases
ATGACATCCGGAATCCTCGTTCTTGTTCTCGTGCTGGTGGCCGGCATGCTGCTGCGCATGCCCATCGGTTTTTCGATGCT
GGCCTCGGGCATTGCCTACCTGATGGTCAAGGGGCAGGACATCGGCCTGGTGGCCGAGCAGGTGGGCAACGGCCTCTACA
ACAGCTATGTGCTGCTGGCCGTGCCGCTCTTCGTGTTTGCGGCCAACATCATGAACGCCGGCACGGTGAGCGAGCGCATT
TTTGACTTCTGCCGCATCCTGGTCGGGCGCGTGCGCGGCGGCCTGGCGCAAGTGGATATTCTGGTGAGCGTGGTGTTCTC
GGGCATGAGCGGCAGCGCCATTGCCGACGCCGCCGGGCCCGGCCTGGTCACCATTCGCCAGATGCTCAAGAAGCCGGAAT
ACACACGCGGCTTTGCGGGTGCCGTGGTGGTGGCCAGCGCCACACTCGGACCCATCATTCCGCCTTCCATTCCCATGGTG
ATTTACGCCCTGGTGTCGGGCGCTTCGGTGGGGGCGCTGTTTCTGGGTGGTGTGGTGCCGGGCTTTTTGATGGCATTTTT
GATGATGGCAGTGGTGCATTTCATTGCCGTGAAACGCAACATGCCGCGTGAAGACAAAATTCCGCTGAGTGAATGGCCGA
GCATCATCTTTCGCGGCGCCCTGCCGCTGTCCATGCCCATCGTGCTGCTCGGTGGCATTTACTCCGGCGCCTTCACGCCC
ACAGAAGCCGCCGCGGTGGCTGCTTTTCATGCGCTGGTGCTGGCGGGGGTGGTTTACCGCGCGCTGACCTGGCGCACCTT
CTGGGGCGTGATCATGGAGTCCACCCGCGGCAGCGCCGTCATCACCATGATCCTGGCCGGCTCCTTCATGCTCAATTACG
CATTCACCGCCGAAGGCGTGCCGCAAGCCATGGCCACGTGGGTCGACAGCATGCAGCTCTCGCAGATCAAGTTTTTGCTG
CTGGTCAACGTGATGTTCCTGGTGCTGGGCTGCTTTCTGGATGTGTCGGTGCTGCTGCTGGTGTTTGTGCCCATGCTGCT
GCCCGCGGCCAAGCTGCTGGGCGTGGACCTGGTGCACTTTGGCGTGCTGGTGGTGCTCAACATGATGATCGGCCTGATCC
ACCCGCCCTTTGGCATGCTGCTGTTCGTAACCAAGGCGCTGACCGGCATCCCGATTGGCGAAATGATGAAAGAAGGCTGG
CATTTCCTGGTCATGCTGCTGCTCTTGCTGCTCGCCATGACCTGCTTTCCACAAATTGTGCTGTGGCTGCCGCAAACCAT
GGGCTACGGAGGCAAATAG

Upstream 100 bases:

>100_bases
TTTTGCCTTTTGTGCTGCTGCTGGCGGCACTGGTTGTTCGCTCTGCGTGGGCCATCTGGAACGCGATTCGGGGTGTTGGT
CTTGAAGCGGAGTTGCGCAT

Downstream 100 bases:

>100_bases
TGAGCCACCCGGATAGCCCCGCCGGCGCCGCAGAGCCCGTAGCAATAACAGCCACCGAAGCGCCTGCCGAGGTGGTCTGC
GTGGCCAGCTGGAATGCCGA

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTSGILVLVLVLVAGMLLRMPIGFSMLASGIAYLMVKGQDIGLVAEQVGNGLYNSYVLLAVPLFVFAANIMNAGTVSERI
FDFCRILVGRVRGGLAQVDILVSVVFSGMSGSAIADAAGPGLVTIRQMLKKPEYTRGFAGAVVVASATLGPIIPPSIPMV
IYALVSGASVGALFLGGVVPGFLMAFLMMAVVHFIAVKRNMPREDKIPLSEWPSIIFRGALPLSMPIVLLGGIYSGAFTP
TEAAAVAAFHALVLAGVVYRALTWRTFWGVIMESTRGSAVITMILAGSFMLNYAFTAEGVPQAMATWVDSMQLSQIKFLL
LVNVMFLVLGCFLDVSVLLLVFVPMLLPAAKLLGVDLVHFGVLVVLNMMIGLIHPPFGMLLFVTKALTGIPIGEMMKEGW
HFLVMLLLLLLAMTCFPQIVLWLPQTMGYGGK

Sequences:

>Translated_432_residues
MTSGILVLVLVLVAGMLLRMPIGFSMLASGIAYLMVKGQDIGLVAEQVGNGLYNSYVLLAVPLFVFAANIMNAGTVSERI
FDFCRILVGRVRGGLAQVDILVSVVFSGMSGSAIADAAGPGLVTIRQMLKKPEYTRGFAGAVVVASATLGPIIPPSIPMV
IYALVSGASVGALFLGGVVPGFLMAFLMMAVVHFIAVKRNMPREDKIPLSEWPSIIFRGALPLSMPIVLLGGIYSGAFTP
TEAAAVAAFHALVLAGVVYRALTWRTFWGVIMESTRGSAVITMILAGSFMLNYAFTAEGVPQAMATWVDSMQLSQIKFLL
LVNVMFLVLGCFLDVSVLLLVFVPMLLPAAKLLGVDLVHFGVLVVLNMMIGLIHPPFGMLLFVTKALTGIPIGEMMKEGW
HFLVMLLLLLLAMTCFPQIVLWLPQTMGYGGK
>Mature_431_residues
TSGILVLVLVLVAGMLLRMPIGFSMLASGIAYLMVKGQDIGLVAEQVGNGLYNSYVLLAVPLFVFAANIMNAGTVSERIF
DFCRILVGRVRGGLAQVDILVSVVFSGMSGSAIADAAGPGLVTIRQMLKKPEYTRGFAGAVVVASATLGPIIPPSIPMVI
YALVSGASVGALFLGGVVPGFLMAFLMMAVVHFIAVKRNMPREDKIPLSEWPSIIFRGALPLSMPIVLLGGIYSGAFTPT
EAAAVAAFHALVLAGVVYRALTWRTFWGVIMESTRGSAVITMILAGSFMLNYAFTAEGVPQAMATWVDSMQLSQIKFLLL
VNVMFLVLGCFLDVSVLLLVFVPMLLPAAKLLGVDLVHFGVLVVLNMMIGLIHPPFGMLLFVTKALTGIPIGEMMKEGWH
FLVMLLLLLLAMTCFPQIVLWLPQTMGYGGK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=395, Percent_Identity=33.1645569620253, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46121; Mature: 45990

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCC
>Mature Secondary Structure 
TSGILVLVLVLVAGMLLRMPIGFSMLASGIAYLMVKGQDIGLVAEQVGNGLYNSYVLLA
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHH
VPLFVFAANIMNAGTVSERIFDFCRILVGRVRGGLAQVDILVSVVFSGMSGSAIADAAGP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHCCCC
GLVTIRQMLKKPEYTRGFAGAVVVASATLGPIIPPSIPMVIYALVSGASVGALFLGGVVP
CHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
GFLMAFLMMAVVHFIAVKRNMPREDKIPLSEWPSIIFRGALPLSMPIVLLGGIYSGAFTP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCCC
TEAAAVAAFHALVLAGVVYRALTWRTFWGVIMESTRGSAVITMILAGSFMLNYAFTAEGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
PQAMATWVDSMQLSQIKFLLLVNVMFLVLGCFLDVSVLLLVFVPMLLPAAKLLGVDLVHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLVVLNMMIGLIHPPFGMLLFVTKALTGIPIGEMMKEGWHFLVMLLLLLLAMTCFPQIV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWLPQTMGYGGK
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]