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The map label for this gene is dapA2 [H]

Identifier: 91788068

GI number: 91788068

Start: 2290556

End: 2291458

Strand: Reverse

Name: dapA2 [H]

Synonym: Bpro_2195

Alternate gene names: 91788068

Gene position: 2291458-2290556 (Counterclockwise)

Preceding gene: 91788070

Following gene: 91788061

Centisome position: 44.06

GC content: 65.89

Gene sequence:

>903_bases
ATGCAAACAGCGCGCAATGCAAACCAGGTAACCCCGGTAACTCCGGATTTCTCGGGGCTCTGGATCCCGCTTGTCACCCC
TTTTGACCACGGCCAGGTTGACCATGCGTCCTTGAAGCGCCTGGTGGCGCACTACCGCGGCAGCGGCATTGCCGGCCTGG
TGGCCTGCGGCTCCACGGGCGAAGCAGCAGCCTTGAGCGACGAAGAGCAGCTGGCCGTGCTGCAGGCCGTCATGCGGGAA
GCACCTGAACTGCCGGTGGTCATGGGCCTGTCGGGCTACCACCTGGGGAAAACCGCGGCGCGCATCAAAGTGCTGGGCGA
GCTGGGCATTGCCGGCATCCTGCTGCCCGCGCCCCACTACATCCGGCCTGCCCAAGCCGGCCTGATCGAGTGGTTTACCC
AGCTGGCCGACGCCAGTGCCGTGCCGGTCATCCTGTATGACATTCCCTACCGCACCGGTGTGAAGATCGAACTGGAGACC
CTGAGGGCGCTGGCCAGCCATCCACGCATCTGCGCCATCAAGGACTGCGGTGGCGACGCAGACAAAACGCAAGCGCTGAT
CAGGGACGGCCGCCTGCAGGTCTTGTGCGGCGAGGATGGCCATATTTTCTCCACCCTGGCGCAAGGCGGCCATGGTGCGA
TTGCGGCGGCGGCCCATGTGCACACGCGGCGTTTCGTCCAGGGGATGGATCTCATCAGGACCGGCGATGAGGCGCAGGCC
CGCACGCTGTGGGAGCCGCTGCTGCCGCTGATTGAAGGCTTGTTCGCCGAACCCAGCCCAGGCCCGCTGAAAGCCCTGCT
CGCGCGCCGGGGACTGGTTCGCGAAGAACTTCGCAGCCCCATGACCCCGGCCTCTGGCGCGCTGGTTGAACGCCTGCAGC
GGCTGGATGGGTTGATCGGGTAA

Upstream 100 bases:

>100_bases
GCGATGGAGCCGCCAGTTACTTTCAGGTCTTTCCTGCGTGCACCACCTCTTGTTTTGACGATGGCCTTCCAAGCCGGTCA
GTTTTTAAGGATGTGTCTTC

Downstream 100 bases:

>100_bases
ATCAGCCGCCGGTGACGGGCGGGAAAAAAGCGACTTCGCAGCCTTCGCTTAAAACGGCCGACTCGTCACTCATGACCTGG
TTCAGCGCCATGCGCACAGA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS 2 [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MQTARNANQVTPVTPDFSGLWIPLVTPFDHGQVDHASLKRLVAHYRGSGIAGLVACGSTGEAAALSDEEQLAVLQAVMRE
APELPVVMGLSGYHLGKTAARIKVLGELGIAGILLPAPHYIRPAQAGLIEWFTQLADASAVPVILYDIPYRTGVKIELET
LRALASHPRICAIKDCGGDADKTQALIRDGRLQVLCGEDGHIFSTLAQGGHGAIAAAAHVHTRRFVQGMDLIRTGDEAQA
RTLWEPLLPLIEGLFAEPSPGPLKALLARRGLVREELRSPMTPASGALVERLQRLDGLIG

Sequences:

>Translated_300_residues
MQTARNANQVTPVTPDFSGLWIPLVTPFDHGQVDHASLKRLVAHYRGSGIAGLVACGSTGEAAALSDEEQLAVLQAVMRE
APELPVVMGLSGYHLGKTAARIKVLGELGIAGILLPAPHYIRPAQAGLIEWFTQLADASAVPVILYDIPYRTGVKIELET
LRALASHPRICAIKDCGGDADKTQALIRDGRLQVLCGEDGHIFSTLAQGGHGAIAAAAHVHTRRFVQGMDLIRTGDEAQA
RTLWEPLLPLIEGLFAEPSPGPLKALLARRGLVREELRSPMTPASGALVERLQRLDGLIG
>Mature_300_residues
MQTARNANQVTPVTPDFSGLWIPLVTPFDHGQVDHASLKRLVAHYRGSGIAGLVACGSTGEAAALSDEEQLAVLQAVMRE
APELPVVMGLSGYHLGKTAARIKVLGELGIAGILLPAPHYIRPAQAGLIEWFTQLADASAVPVILYDIPYRTGVKIELET
LRALASHPRICAIKDCGGDADKTQALIRDGRLQVLCGEDGHIFSTLAQGGHGAIAAAAHVHTRRFVQGMDLIRTGDEAQA
RTLWEPLLPLIEGLFAEPSPGPLKALLARRGLVREELRSPMTPASGALVERLQRLDGLIG

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=291, Percent_Identity=28.5223367697594, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1788823, Length=277, Percent_Identity=34.2960288808664, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1786463, Length=240, Percent_Identity=31.6666666666667, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082415, Length=242, Percent_Identity=28.5123966942149, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789620, Length=285, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31987; Mature: 31987

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTARNANQVTPVTPDFSGLWIPLVTPFDHGQVDHASLKRLVAHYRGSGIAGLVACGSTG
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCC
EAAALSDEEQLAVLQAVMREAPELPVVMGLSGYHLGKTAARIKVLGELGIAGILLPAPHY
CCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEECCCCC
IRPAQAGLIEWFTQLADASAVPVILYDIPYRTGVKIELETLRALASHPRICAIKDCGGDA
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEHHHHHHHHCCCCEEEEECCCCCH
DKTQALIRDGRLQVLCGEDGHIFSTLAQGGHGAIAAAAHVHTRRFVQGMDLIRTGDEAQA
HHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RTLWEPLLPLIEGLFAEPSPGPLKALLARRGLVREELRSPMTPASGALVERLQRLDGLIG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQTARNANQVTPVTPDFSGLWIPLVTPFDHGQVDHASLKRLVAHYRGSGIAGLVACGSTG
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCC
EAAALSDEEQLAVLQAVMREAPELPVVMGLSGYHLGKTAARIKVLGELGIAGILLPAPHY
CCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEECCCCC
IRPAQAGLIEWFTQLADASAVPVILYDIPYRTGVKIELETLRALASHPRICAIKDCGGDA
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEHHHHHHHHCCCCEEEEECCCCCH
DKTQALIRDGRLQVLCGEDGHIFSTLAQGGHGAIAAAAHVHTRRFVQGMDLIRTGDEAQA
HHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RTLWEPLLPLIEGLFAEPSPGPLKALLARRGLVREELRSPMTPASGALVERLQRLDGLIG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]